Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase

Neuropsychopharmacology

Volumn 36, Issue 5, 2011, Pages 1047-1059

  Collins, Gregory T ^a   Carey, Kathy A ^a   Narasimhan, Diwahar ^a   Nichols, Joseph ^a   Berlin, Aaron A ^a   Lukacs, Nicholas W ^a   Sunahara, Roger K ^a   Woods, James H ^a   Ko, Mei Chuan ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

acute cocaine toxicity; cardiovascular; cocaine; cocaine esterase; DM CocE; rhesus monkey

Indexed keywords

CARBOXYLESTERASE; COCAINE;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; CORE TEMPERATURE; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; ELECTROCARDIOGRAPHY; FEMALE; HEART PROTECTION; HEART RATE VARIABILITY; HYPERTHERMIA; IMMUNE RESPONSE; LOCOMOTION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD PRESSURE; BODY TEMPERATURE; CARBOXYLIC ESTER HYDROLASES; CARDIOVASCULAR SYSTEM; COCAINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEART RATE; INJECTIONS, INTRAVENOUS; MACACA MULATTA; MALE; MOTOR ACTIVITY; MUTATION; RECOMBINANT PROTEINS;

EID: 79952761035     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.242     Document Type: Article

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