Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine

Chemico-Biological Interactions

Volumn 187, Issue 1-3, 2010, Pages 148-152

  Yang, Wenchao ^a   Xue, Liu ^a   Fang, Lei ^a   Chen, Xi ^a   Zhan, Chang Guo ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Cocaine addiction; Drug overdose; Enzyme therapy; Hydrolase

Indexed keywords

ACETYLTHIOCHOLINE; ALANINE; BUTYRYLTHIOCHOLINE; CHOLINESTERASE; COCAINE; GLYCINE; HUMAN SERUM ALBUMIN; SERINE; TRYPTOPHAN; TYROSINE;

ARTICLE; CATALYSIS; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG HALF LIFE; DRUG MECHANISM; EMBRYO; ENZYME ACTIVITY; ENZYME SUBSTRATE; ENZYME THERAPY; HUMAN; HUMAN CELL; HYDROLYSIS; MUTANT; WILD TYPE;

EID: 77955517250     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.01.004     Document Type: Article

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