Effects of cocaine esterase following its repeated administration with cocaine in mice

Drug and Alcohol Dependence

Volumn 101, Issue 3, 2009, Pages 202-209

  Ko, Mei Chuan ^a,b   Narasimhan, Diwahar ^a   Berlin, Aaron A ^a   Lukacs, Nicholas W ^a   Sunahara, Roger K ^a   Woods, James H ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Department of Psychology   (Taiwan)

Author keywords

Cocaine esterase; Cocaine toxicity; Convulsions; Immunogenicity; Lethality

Indexed keywords

CARBOXYLESTERASE; COCAINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; CONVULSION; DRUG DOSE ESCALATION; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNE RESPONSE; LETHALITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPEATED DRUG DOSE;

ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; CARBOXYLIC ESTER HYDROLASES; COCAINE; COCAINE-RELATED DISORDERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MALE; MICE; POSTURE; SEIZURES;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS;

EID: 61849163341     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2009.01.002     Document Type: Article

References (19)

1. Afonso L., Mohammad T., and Thatai D. Crack chips the heart: a review of the cardiovascular toxicity of cocaine. Am. J. Cardiol. 100 (2007) 1040-1043
2. Benowitz N.L. Clinical pharmacology and toxicology of cocaine. Pharmacol. Toxicol. 72 (1993) 3-12
3. Bresler M.M., Rosser S.J., Basran A., and Bruce N.C. Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1. Appl. Environ. Microbiol. 66 (2000) 904-908
4. Cooper Z.D., Narasimhan D., Sunahara R.K., Mierzejewski P., Jutkiewicz E.M., Larsen N.A., Wilson I.A., Landry D.W., and Woods J.H. Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase. Mol. Pharmacol. 70 (2006) 1885-1891
5. De Groot A.S., and Scott D.W. Immunogenicity of protein therapeutics. Trends Immunol. 28 (2007) 482-490
6. Devlin R.J., and Henry J.A. Clinical review: major consequences of illicit drug consumption. Crit. Care 12 (2008) p. 202 10.1186/cc6166 Epub 2008 January
7. Dickerson T.J., and Janda K.D. Recent advances for the treatment of cocaine abuse: central nervous system immunopharmacotherapy. AAPS J. 7 (2005) E579-E586
8. Egred M., and Davis G.K. Cocaine and the heart. Postgrad. Med. J. 81 (2005) 568-571
9. Gorelick D.A. Pharmacokinetic approaches to treatment of drug addiction. Exp. Rev. Clin. Pharmacol. 1 (2008) 277-290
10. Harris J.M., and Chess R.B. Effect of pegylation on pharmaceuticals. Natl. Rev. Drug Discov. 2 (2003) 214-221
11. Inaba T., Stewart D., and Kalow W. Metabolism of cocaine in man. Clin. Pharmacol. Ther. 23 (1978) 547-552
12. Ko M.C., Bowen L.D., Narasimhan D., Berlin A.A., Lukacs N.W., Sunahara R.K., Cooper Z.D., and Woods J.H. Cocaine esterase: interactions with cocaine and immune responses in mice. J. Pharmacol. Exp. Ther. 320 (2007) 926-933
13. Larsen N.A., Turner J.M., Stevens J., Rosser S.J., Basran A., Lerner R.A., Bruce N.C., and Wilson I.A. Crystal structure of a bacterial cocaine esterase. Nat. Struct. Biol. 9 (2002) 17-21
14. National Institute on Drug Abuse, 2004. Cocaine abuse and addiction. NIDA Research Report Series. NIH Publication Number 99-4342 (Rev. November 2004).
15. Substance Abuse and Mental Health Services Administration, 2006. Drug Abuse Warning Network, 2004: National Estimates of Drug-Related Emergency Department Visits (Office of Applied Studies, DAWN Series D-28, DHHS Publication No. SMA 06-4143). Rockville, MD.
16. Sofuoglu M., and Kosten T.R. Novel approaches to the treatment of cocaine addiction. CNS Drugs 19 (2005) 13-25
17. Turner J.M., Larsen N.A., Basran A., Barbas III C.F., Bruce N.C., Wilson I.A., and Lerner R.A. Biochemical characterization and structural analysis of a highly proficient cocaine esterase. Biochemistry 41 (2002) 12297-12307
18. Veronese F.M., and Mero A. The impact of PEGylation on biological therapies. BioDrugs 22 (2008) 315-329
19. Vocci F.J., Acri J., and Elkashef A. Medication development for addictive disorders: the state of the science. Am. J. Psychiatry 162 (2005) 1432-1440