Rapid and robust protection against cocaine-induced lethality in rats by the bacterial cocaine esterase

Molecular Pharmacology

Volumn 70, Issue 6, 2006, Pages 1885-1891

  Cooper, Ziva D ^a,b   Narasimhan, Diwahar ^a   Sunahara, Roger K ^a   Mierzejewski, Pawel ^c,g   Jutkiewicz, Emily M ^a   Larsen, Nicholas A ^d   Wilson, Ian A ^e   Landry, Donald W ^f   Woods, James H ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f NewYork Presbyterian Hospital   (United States)

^g INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLESTERASE; CHOLINESTERASE; COCAINE; TROPARIL;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; CONVULSION; DOSE RESPONSE; DRUG ACTIVITY; DRUG DEGRADATION; DRUG OVERDOSE; DRUG TREATMENT FAILURE; HYDROLYSIS; IN VIVO STUDY; LETHALITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BACTERIA; BUTYRYLCHOLINESTERASE; CARBOXYLIC ESTER HYDROLASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COCAINE; HUMANS; HYDROLYSIS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33751097261     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.025999     Document Type: Article

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