-
1
-
-
77952780984
-
Not all autophagy membranes are created equal
-
McEwan DG, Dikic I. Not all autophagy membranes are created equal. Cell 2010;141:564-6.
-
(2010)
Cell
, vol.141
, pp. 564-566
-
-
McEwan, D.G.1
Dikic, I.2
-
2
-
-
70449927247
-
Autophagy is required to maintain muscle mass
-
Masiero E, Agatea L, Mammucari C, et al. Autophagy is required to maintain muscle mass. Cell Metab 2009;10:507-15.
-
(2009)
Cell Metab
, vol.10
, pp. 507-515
-
-
Masiero, E.1
Agatea, L.2
Mammucari, C.3
-
3
-
-
8344242220
-
Autophagy in health and disease: A double-edged sword
-
DOI 10.1126/science.1099993
-
Shintani T, Klionsky DJ. Autophagy in health and disease: a doubleedged sword. Science 2004;306:990-5. (Pubitemid 39482894)
-
(2004)
Science
, vol.306
, Issue.5698
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
6
-
-
25144506835
-
Autophagy in cell death: An innocent convict?
-
DOI 10.1172/JCI26390
-
Levine B, Yuan J. Autophagy in cell death: an innocent convict? J Clin Invest 2005;115:2679-88. (Pubitemid 41434392)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.10
, pp. 2679-2688
-
-
Levine, B.1
Yuan, J.2
-
7
-
-
77950994646
-
Autophagy: Cellular and molecular mechanisms
-
Glick D, Barth S, Macleod KF. Autophagy: cellular and molecular mechanisms. J Pathol 2010;221:3-12.
-
(2010)
J Pathol
, vol.221
, pp. 3-12
-
-
Glick, D.1
Barth, S.2
MacLeod, K.F.3
-
8
-
-
0038309329
-
The molecular mechanism of autophagy
-
Wang CW, Klionsky DJ. The molecular mechanism of autophagy. Mol Med 2003;9:65-76. (Pubitemid 36819962)
-
(2003)
Molecular Medicine
, vol.9
, Issue.3-4
, pp. 65-76
-
-
Wang, C.-W.1
Klionsky, D.J.2
-
9
-
-
0347626252
-
Autophagy: A regulated bulk degradation process inside cells
-
DOI 10.1016/j.bbrc.2003.07.023
-
Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 2004;313:453-8. (Pubitemid 37543608)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.313
, Issue.2
, pp. 453-458
-
-
Yoshimori, T.1
-
12
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008;132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
13
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N, Yoshimori T, Levine B. Methods in mammalian autophagy research. Cell 2010;140:313-26.
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
14
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
DOI 10.1038/nature06639, PII NATURE06639
-
Mizushima N, Levine B, Cuervo AM, et al. Autophagy fights disease through cellular self-digestion. Nature 2008;451:1069-75. (Pubitemid 351317450)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
15
-
-
53049102656
-
The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function
-
Obara K, Sekito T, Niimi K, et al. The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function. J Biol Chem 2008; 283:23972-80.
-
(2008)
J Biol Chem
, vol.283
, pp. 23972-23980
-
-
Obara, K.1
Sekito, T.2
Niimi, K.3
-
16
-
-
67650021571
-
Autophagy: A double-edged sword in oncology
-
Apel A, Zentgraf H, Buchler MW, et al. Autophagy: a double-edged sword in oncology. Int J Cancer 2009;125:991-5.
-
(2009)
Int J Cancer
, vol.125
, pp. 991-995
-
-
Apel, A.1
Zentgraf, H.2
Buchler, M.W.3
-
17
-
-
65649083316
-
Autophagy and ethanol-induced liver injury
-
Donohue TM Jr. Autophagy and ethanol-induced liver injury. World J Gastroenterol 2009;15:1178-85.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 1178-1185
-
-
Donohue Jr., T.M.1
-
18
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
Hosokawa N, Hara T, Kaizuka T, et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell 2009;20:1981-91.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
-
19
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis P, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008;4:151-75. (Pubitemid 351231180)
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
Agrawal, D.K.4
Aliev, G.5
Askew, D.S.6
Baba, M.7
Baehrecke, E.H.8
Bahr, B.A.9
Ballabio, A.10
Bamber, B.A.11
Bassham, D.C.12
Bergamini, E.13
Bi, X.14
Biard-Piechaczyk, M.15
Blum, J.S.16
Bredesen, D.E.17
Brodsky, J.L.18
Brumell, J.H.19
Brunk, U.T.20
Bursch, W.21
Camougrand, N.22
Cebollero, E.23
Cecconi, F.24
Chen, Y.25
Chin, L.-S.26
Choi, A.27
Chu, C.T.28
Chung, J.29
Clarke, P.G.H.30
Clark, R.S.B.31
Clarke, S.G.32
Clave, C.33
Cleveland, J.L.34
Codogno, P.35
Colombo, M.I.36
Cotomontes, A.37
Cregg, J.M.38
Cuervo, A.M.39
Debnath, J.40
Demarchi, F.41
Dennis, P.B.42
Dennis, P.A.43
Deretic, V.44
Devenish, R.J.45
Di Sano, F.46
Dice, J.F.47
DiFiglia, M.48
Dinesh-Kumar, S.49
Distelhorst, C.W.50
Djavaheri-Mergny, M.51
Dorsey, F.C.52
Droge, W.53
Dron, M.54
Dunn Jr., W.A.55
Duszenko, M.56
Eissa, N.T.57
Elazar, Z.58
Esclatine, A.59
Eskelinen, E.-L.60
Fesus, L.61
Finley, K.D.62
Fuentes, J.M.63
Fueyo, J.64
Fujisaki, K.65
Galliot, B.66
Gao, F.-B.67
Gewirtz, D.A.68
Gibson, S.B.69
Gohla, A.70
Goldberg, A.L.71
Gonzalez, R.72
Gonzalez-Estevez, C.73
Gorski, S.74
Gottlieb, R.A.75
Haussinger, D.76
He, Y.-W.77
Heidenreich, K.78
Hill, J.A.79
Hoyer-Hansen, M.80
Hu, X.81
Huang, W.-P.82
Iwasaki, A.83
Jaattela, M.84
Jackson, W.T.85
Jiang, X.86
Jin, S.87
Johansen, T.88
Jung, J.U.89
Kadowaki, M.90
Kang, C.91
Kelekar, A.92
Kessel, D.H.93
Kiel, J.A.K.W.94
Hong, P.K.95
Kimchi, A.96
more..
-
20
-
-
0035503594
-
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
-
DOI 10.1093/emboj/20.21.5971
-
Suzuki K, Kirisako T, Kamada Y, et al. The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J 2001;20:5971-81. (Pubitemid 33049272)
-
(2001)
EMBO Journal
, vol.20
, Issue.21
, pp. 5971-5981
-
-
Suzuki, K.1
Kirisako, T.2
Kamada, Y.3
Mizushima, N.4
Noda, T.5
Ohsumi, Y.6
-
21
-
-
34248139628
-
Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae
-
DOI 10.1016/j.febslet.2007.01.096, PII S0014579307002554, Membrane Trafficking
-
Suzuki K, Ohsumi Y. Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae. FEBS Lett 2007;581: 2156-61. (Pubitemid 46709906)
-
(2007)
FEBS Letters
, vol.581
, Issue.11
, pp. 2156-2161
-
-
Suzuki, K.1
Ohsumi, Y.2
-
22
-
-
0025340880
-
Studies on the mechanisms of autophagy: Maturation of the autophagic vacuole
-
Dunn WA Jr. Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J Cell Biol 1990;110:1935-45.
-
(1990)
J Cell Biol
, vol.110
, pp. 1935-1945
-
-
Dunn Jr., W.A.1
-
23
-
-
0025217177
-
Characterization of the isolation membranes and the limiting membranes of autophagosomes in rat hepatocytes by lectin cytochemistry
-
Yamamoto A, Masaki R, Tashiro Y. Characterization of the isolation membranes and the limiting membranes of autophagosomes in rat hepatocytes by lectin cytochemistry. J Histochem Cytochem 1990;38: 573-80. (Pubitemid 20106508)
-
(1990)
Journal of Histochemistry and Cytochemistry
, vol.38
, Issue.4
, pp. 573-580
-
-
Yamamoto, A.1
Masaki, R.2
Tashiro, Y.3
-
24
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
Axe EL, Walker SA, Manifava M, et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008;182:685-701.
-
(2008)
J Cell Biol
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
Walker, S.A.2
Manifava, M.3
-
25
-
-
77953507889
-
Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation
-
Hayashi-Nishino M, Fujita N, Noda T, et al. Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation. Autophagy 2010;6:301-3.
-
(2010)
Autophagy
, vol.6
, pp. 301-303
-
-
Hayashi-Nishino, M.1
Fujita, N.2
Noda, T.3
-
26
-
-
71649112895
-
3D tomography reveals connections between the phagophore and endoplasmic reticulum
-
Yla-Anttila P, Vihinen H, Jokitalo E, et al. 3D tomography reveals connections between the phagophore and endoplasmic reticulum. Autophagy 2009;5:1180-5.
-
(2009)
Autophagy
, vol.5
, pp. 1180-1185
-
-
Yla-Anttila, P.1
Vihinen, H.2
Jokitalo, E.3
-
27
-
-
77952495224
-
Mitochondria supply membranes for autophagosome biogenesis during starvation
-
Hailey DW, Rambold AS, Satpute-Krishnan P, et al. Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 2010;141:656-67.
-
(2010)
Cell
, vol.141
, pp. 656-667
-
-
Hailey, D.W.1
Rambold, A.S.2
Satpute-Krishnan, P.3
-
28
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
DOI 10.1016/0014-5793(93)80398-E
-
Tsukada M, Ohsumi Y. Isolation and characterization of autophagydefective mutants of Saccharomyces cerevisiae. FEBS Lett 1993;333: 169-74. (Pubitemid 23306962)
-
(1993)
FEBS Letters
, vol.333
, Issue.1-2
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
29
-
-
0027936092
-
Isolation of autophagocytosis mutants of Saccharomyces cerevisiae
-
DOI 10.1016/0014-5793(94)00672-5
-
Thumm M, Egner R, Koch B, et al. Isolation of autophagocytosis mutants of Saccharomyces cerevisiae. FEBS Lett 1994;349:275-80. (Pubitemid 24263277)
-
(1994)
FEBS Letters
, vol.349
, Issue.2
, pp. 275-280
-
-
Thumm, M.1
-
30
-
-
0028800171
-
Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway
-
Harding TM, Morano KA, Scott SV, et al. Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J Cell Biol 1995;131:591-602.
-
(1995)
J Cell Biol
, vol.131
, pp. 591-602
-
-
Harding, T.M.1
Morano, K.A.2
Scott, S.V.3
-
31
-
-
0030883562
-
Glucose-induced microautophagy in Pichia pastoris requires the α-subunit of phosphofructokinase
-
Yuan W, Tuttle DL, Shi YJ, et al. Glucose-induced microautophagy in Pichia pastoris requires the alpha-subunit of phosphofructokinase. J Cell Sci 1997;110(Pt 16):1935-45. (Pubitemid 27386663)
-
(1997)
Journal of Cell Science
, vol.110
, Issue.16
, pp. 1935-1945
-
-
Yuan, W.1
Tuttle, D.L.2
Shi, Y.-J.3
Ralph, G.S.4
Dunn Jr., W.A.5
-
32
-
-
0032482219
-
Peroxisome degradation by microautophagy in Pichia pastoris: Identification of specific steps and morphological intermediates
-
DOI 10.1083/jcb.141.3.625
-
Sakai Y, Koller A, Rangell LK, et al. Peroxisome degradation by microautophagy in Pichia pastoris: identification of specific steps and morphological intermediates. J Cell Biol 1998;141:625-36. (Pubitemid 28217909)
-
(1998)
Journal of Cell Biology
, vol.141
, Issue.3
, pp. 625-636
-
-
Sakai, Y.1
Koller, A.2
Rangell, L.K.3
Keller, G.A.4
Subramani, S.5
-
33
-
-
0036163982
-
Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagy
-
DOI 10.1046/j.1356-9597.2001.00499.x
-
Mukaiyama H, Oku M, Baba M, et al. Paz2 and 13 other PAZ gene products regulate vacuolar engulfment of peroxisomes during micropexophagy. Genes Cells 2002;7:75-90. (Pubitemid 34121307)
-
(2002)
Genes to Cells
, vol.7
, Issue.1
, pp. 75-90
-
-
Mukaiyama, H.1
Oku, M.2
Baba, M.3
Samizo, T.4
Hammond, A.T.5
Glick, B.S.6
Kato, N.7
Sakai, Y.8
-
34
-
-
0028855063
-
Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha
-
Titorenko VI, Keizer I, Harder W, et al. Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha. J Bacteriol 1995; 177:357-63.
-
(1995)
J Bacteriol
, vol.177
, pp. 357-363
-
-
Titorenko, V.I.1
Keizer, I.2
Harder, W.3
-
35
-
-
10744225487
-
A unified nomenclature for yeast autophagy-related genes
-
DOI 10.1016/S1534-5807(03)00296-X, PII S153458070300296X
-
Klionsky DJ, Cregg JM, Dunn WA Jr, et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell 2003;5:539-45. (Pubitemid 37243044)
-
(2003)
Developmental Cell
, vol.5
, Issue.4
, pp. 539-545
-
-
Klionsky, D.J.1
Cregg, J.M.2
Dunn Jr., W.A.3
Emr, S.D.4
Sakai, Y.5
Sandoval, I.V.6
Sibirny, A.7
Subramani, S.8
Thumm, M.9
Veenhuis, M.10
Ohsumi, Y.11
-
36
-
-
77953543377
-
The Beclin 1-VPS34 complex- at the crossroads of autophagy and beyond
-
Funderburk SF, Wang QJ, Yue Z. The Beclin 1-VPS34 complex- at the crossroads of autophagy and beyond. Trends Cell Biol 2010;20:355-62.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
37
-
-
20344387475
-
Autophagy: Dual roles in life and death?
-
DOI 10.1038/nrm1666
-
Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 2005;6:505-10. (Pubitemid 40780562)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.6
, pp. 505-510
-
-
Baehrecke, E.H.1
-
38
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol 2010;22: 124-31.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
39
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 2009;43:67-93.
-
(2009)
Annu Rev Genet
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
41
-
-
77957597727
-
Discovery of phosphatidylinositol 3-kinase inhibitory compounds from the Screening Committee of Anticancer Drugs (SCADS) library
-
Kong D, Yamazaki K, Yamori T. Discovery of phosphatidylinositol 3-kinase inhibitory compounds from the Screening Committee of Anticancer Drugs (SCADS) library. Biol Pharm Bull 2010;33: 1600-4.
-
(2010)
Biol Pharm Bull
, vol.33
, pp. 1600-1604
-
-
Kong, D.1
Yamazaki, K.2
Yamori, T.3
-
42
-
-
39749141485
-
The regulation and function of Class III PI3Ks: Novel roles for Vps34
-
DOI 10.1042/BJ20071427
-
Backer JM. The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem J 2008;410:1-17. (Pubitemid 351300321)
-
(2008)
Biochemical Journal
, vol.410
, Issue.1
, pp. 1-17
-
-
Backer, J.M.1
-
43
-
-
77951217000
-
Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class i and III phosphoinositide 3-kinase
-
Wu YT, Tan HL, Shui G, et al. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J Biol Chem 2010;285: 10850-61.
-
(2010)
J Biol Chem
, vol.285
, pp. 10850-10861
-
-
Wu, Y.T.1
Tan, H.L.2
Shui, G.3
-
44
-
-
0032563798
-
A protein conjugation system essential for autophagy
-
DOI 10.1038/26506
-
Mizushima N, Noda T, Yoshimori T, et al. A protein conjugation system essential for autophagy. Nature 1998;395:395-8. (Pubitemid 28450691)
-
(1998)
Nature
, vol.395
, Issue.6700
, pp. 395-398
-
-
Mizushima, N.1
Noda, T.2
Yoshimori, T.3
Tanaka, Y.4
Ishii, T.5
George, M.D.6
Klionsky, D.J.7
Ohsumi, M.8
Ohsumi, Y.9
-
45
-
-
0032898636
-
Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy
-
Tanida I, Mizushima N, Kiyooka M, et al. Apg7p/Cvt2p: a novel protein-activating enzyme essential for autophagy. Mol Biol Cell 1999;10:1367-79. (Pubitemid 29230896)
-
(1999)
Molecular Biology of the Cell
, vol.10
, Issue.5
, pp. 1367-1379
-
-
Tanida, I.1
Mizushima, N.2
Kiyooka, M.3
Ohsumi, M.4
Ueno, T.5
Ohsumi, Y.6
Kominami, E.7
-
47
-
-
0033214582
-
Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast
-
DOI 10.1093/emboj/18.19.5234
-
Shintani T, Mizushima N, Ogawa Y, et al. Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast. EMBO J 1999;18:5234-41. (Pubitemid 29465574)
-
(1999)
EMBO Journal
, vol.18
, Issue.19
, pp. 5234-5241
-
-
Shintani, T.1
Mizushima, N.2
Ogawa, Y.3
Matsuura, A.4
Noda, T.5
Ohsumi, Y.6
-
49
-
-
51049118332
-
The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. "protein modifications: Beyond the usual suspects" review series
-
Geng J, Klionsky DJ. The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. "Protein modifications: beyond the usual suspects" review series. EMBO Rep 2008;9:859-64.
-
(2008)
EMBO Rep
, vol.9
, pp. 859-864
-
-
Geng, J.1
Klionsky, D.J.2
-
50
-
-
38049098543
-
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
-
Hanada T, Noda NN, Satomi Y, et al. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem 2007;282:37298-302.
-
(2007)
J Biol Chem
, vol.282
, pp. 37298-37302
-
-
Hanada, T.1
Noda, N.N.2
Satomi, Y.3
-
51
-
-
0347695019
-
A Single Protease, Apg4B, Is Specific for the Autophagy-related Ubiquitin-like Proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L
-
DOI 10.1074/jbc.M308762200
-
Hemelaar J, Lelyveld VS, Kessler BM, et al. A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L. J Biol Chem 2003; 278:51841-50. (Pubitemid 38020431)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.51
, pp. 51841-51850
-
-
Hemelaar, J.1
Lelyveld, V.S.2
Kessler, B.M.3
Ploegh, H.L.4
-
52
-
-
47549092694
-
Atg8 controls phagophore expansion during autophagosome formation
-
Xie Z, Nair U, Klionsky DJ. Atg8 controls phagophore expansion during autophagosome formation. Mol Biol Cell 2008;19:3290-8.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3290-3298
-
-
Xie, Z.1
Nair, U.2
Klionsky, D.J.3
-
53
-
-
0037134443
-
Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p
-
DOI 10.1074/jbc.M200385200
-
Tanida I, Tanida-Miyake E, Komatsu M, et al. Human Apg3p/ Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p. J Biol Chem 2002;277:13739-44. (Pubitemid 34967976)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.16
, pp. 13739-13744
-
-
Tanida, I.1
Tanida-Miyake, E.2
Komatsu, M.3
Ueno, T.4
Kominami, E.5
-
54
-
-
0035910423
-
The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
-
Tanida I, Tanida-Miyake E, Ueno T, et al. The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J Biol Chem 2001;276:1701-6. (Pubitemid 32109639)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.3
, pp. 1701-1706
-
-
Tanida, I.1
Tanida-Miyake, E.2
Ueno, T.3
Kominami, E.4
-
55
-
-
3242888703
-
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
-
DOI 10.1242/jcs.01131
-
Kabeya Y, Mizushima N, Yamamoto A, et al. LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci 2004;117:2805-12. (Pubitemid 38997262)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2805-2812
-
-
Kabeya, Y.1
Mizushima, N.2
Yamamoto, A.3
Oshitani-Okamoto, S.4
Ohsumi, Y.5
Yoshimori, T.6
-
56
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000;19:5720-8.
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
-
57
-
-
0344142468
-
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
-
DOI 10.1006/geno.1999.5851
-
Aita VM, Liang XH, Murty VV, et al. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 1999;59:59-65. (Pubitemid 29339873)
-
(1999)
Genomics
, vol.59
, Issue.1
, pp. 59-65
-
-
Aita, V.M.1
Liang, X.H.2
Murty, V.V.V.S.3
Pincus, D.L.4
Yu, W.5
Cayanis, E.6
Kalachikov, S.7
Gilliam, T.C.8
Levine, B.9
-
58
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999;402:672-6. (Pubitemid 129516338)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
59
-
-
58149084586
-
Decreased expression of autophagyrelated proteins in malignant epithelial ovarian cancer
-
Shen Y, Li DD, Wang LL, et al. Decreased expression of autophagyrelated proteins in malignant epithelial ovarian cancer. Autophagy 2008;4:1067-8.
-
(2008)
Autophagy
, vol.4
, pp. 1067-1068
-
-
Shen, Y.1
Li, D.D.2
Wang, L.L.3
-
60
-
-
34047271129
-
Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours
-
Miracco C, Cosci E, Oliveri G, et al. Protein and mRNA expression of autophagy gene Beclin 1 in human brain tumours. Int J Oncol 2007;30:429-36.
-
(2007)
Int J Oncol
, vol.30
, pp. 429-436
-
-
Miracco, C.1
Cosci, E.2
Oliveri, G.3
-
61
-
-
34848845834
-
Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells
-
DOI 10.1016/j.ygyno.2007.05.034, PII S0090825807003988
-
Wang ZH, Xu L, Duan ZL, et al. Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells. Gynecol Oncol 2007;107:107-13. (Pubitemid 47495947)
-
(2007)
Gynecologic Oncology
, vol.107
, Issue.1
, pp. 107-113
-
-
Wang, Z.-h.1
Xu, L.2
Duan, Z.-l.3
Zeng, L.-q.4
Yan, N.-h.5
Peng, Z.-l.6
-
62
-
-
19544373434
-
Beclin 1 augmented cis-diamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity
-
DOI 10.1016/j.yexcr.2005.02.023, PII S0014482705000911
-
Furuya D, Tsuji N, Yagihashi A, et al. Beclin 1 augmented cisdiamminedichloroplatinum induced apoptosis via enhancing caspase-9 activity. Exp Cell Res 2005;307:26-40. (Pubitemid 40732731)
-
(2005)
Experimental Cell Research
, vol.307
, Issue.1
, pp. 26-40
-
-
Furuya, D.1
Tsuji, N.2
Yagihashi, A.3
Watanabe, N.4
-
63
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
DOI 10.1172/JCI200320039
-
Qu X, Yu J, Bhagat G, et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 2003;112:1809-20. (Pubitemid 38063704)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
Rosen, J.7
Eskelinen, E.-L.8
Mizushima, N.9
Ohsumi, Y.10
Cattoretti, G.11
Levine, B.12
-
64
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
DOI 10.1073/pnas.2436255100
-
Yue Z, Jin S, Yang C, et al. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 2003;100:15077-82. (Pubitemid 37518019)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
65
-
-
0035870257
-
Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function
-
Liang XH, Yu J, Brown K, et al. Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res 2001;61:3443-9. (Pubitemid 32695039)
-
(2001)
Cancer Research
, vol.61
, Issue.8
, pp. 3443-3449
-
-
Xiao Huan Liang1
Yu, J.2
Brown, K.3
Levine, B.4
-
66
-
-
34249274942
-
Beclin 1 gene inhibits tumor growth in colon cancer cell lines
-
Koneri K, Goi T, Hirono Y, et al. Beclin 1 gene inhibits tumor growth in colon cancer cell lines. Anticancer Res 2007;27:1453-7 (Pubitemid 46807222)
-
(2007)
Anticancer Research
, vol.27
, Issue.3 B
, pp. 1453-1457
-
-
Koneri, K.1
Goi, T.2
Hirono, Y.3
Katayama, K.4
Yamaguchi, A.5
-
67
-
-
34347404887
-
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
-
DOI 10.1101/gad.1565707
-
Karantza-Wadsworth V, Patel S, Kravchuk O, et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev 2007;21:1621-35. (Pubitemid 47026367)
-
(2007)
Genes and Development
, vol.21
, Issue.13
, pp. 1621-1635
-
-
Karantza-Wadsworth, V.1
Patel, S.2
Kravchuk, O.3
Chen, G.4
Mathew, R.5
Jin, S.6
White, E.7
-
68
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
Liang C, Feng P, Ku B, et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 2006;8:688-99.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
-
69
-
-
33846204370
-
UVRAG: A new player in autophagy and tumor cell growth
-
Liang C, Feng P, Ku B, et al. UVRAG: a new player in autophagy and tumor cell growth. Autophagy 2007;3:69-71. (Pubitemid 46100721)
-
(2007)
Autophagy
, vol.3
, Issue.1
, pp. 69-71
-
-
Feng, C.1
Feng, P.2
Ku, B.3
Oh, B.-H.4
Jung, J.U.5
-
70
-
-
34848899280
-
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
-
DOI 10.1038/ncb1634, PII NCB1634
-
Takahashi Y, Coppola D, Matsushita N, et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 2007;9:1142-51. (Pubitemid 47500490)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.10
, pp. 1142-1151
-
-
Takahashi, Y.1
Coppola, D.2
Matsushita, N.3
Cualing, H.D.4
Sun, M.5
Sato, Y.6
Liang, C.7
Jung, J.U.8
Cheng, J.Q.9
Mule, J.J.10
Pledger, W.J.11
Wang, H.-G.12
-
71
-
-
55849126198
-
Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma
-
Coppola D, Khalil F, Eschrich SA, et al. Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma. Cancer 2008; 113:2665-70.
-
(2008)
Cancer
, vol.113
, pp. 2665-2670
-
-
Coppola, D.1
Khalil, F.2
Eschrich, S.A.3
-
72
-
-
0035929650
-
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
-
Arico S, Petiot A, Bauvy C, et al. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J Biol Chem 2001;276: 35243-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 35243-35246
-
-
Arico, S.1
Petiot, A.2
Bauvy, C.3
-
73
-
-
33644834046
-
Tumours and tremors: How PTEN regulation underlies both
-
DOI 10.1038/sj.bjc.6602994, PII 6602994
-
Kim RH, Mak TW. Tumours and tremors: how PTEN regulation underlies both. Br J Cancer 2006;94:620-4. (Pubitemid 43361890)
-
(2006)
British Journal of Cancer
, vol.94
, Issue.5
, pp. 620-624
-
-
Kim, R.H.1
Mak, T.W.2
-
74
-
-
0037310664
-
Physiological functions of Pten in mouse tissues
-
Kishimoto H, Hamada K, Saunders M, et al. Physiological functions of Pten in mouse tissues. Cell Struct Funct 2003;28:11-21. (Pubitemid 36443125)
-
(2003)
Cell Structure and Function
, vol.28
, Issue.1
, pp. 11-21
-
-
Kishimoto, H.1
Hamada, K.2
Saunders, M.3
Backman, S.4
Sasaki, T.5
Nakano, T.6
Mak, T.W.7
Suzuki, A.8
-
75
-
-
35148826938
-
Shaping Genetic Alterations in Human Cancer: The p53 Mutation Paradigm
-
DOI 10.1016/j.ccr.2007.10.001, PII S153561080700270X
-
Soussi T, Wiman KG. Shaping genetic alterations in human cancer: the p53 mutation paradigm. Cancer Cell 2007;12:303-12. (Pubitemid 47539312)
-
(2007)
Cancer Cell
, vol.12
, Issue.4
, pp. 303-312
-
-
Soussi, T.1
Wiman, K.G.2
-
76
-
-
20444363122
-
The coordinate regulation of the p53 and mTOR pathways in cells
-
DOI 10.1073/pnas.0502857102
-
Feng Z, Zhang H, Levine AJ, et al. The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci USA 2005;102: 8204-9. (Pubitemid 40800067)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.23
, pp. 8204-8209
-
-
Feng, Z.1
Zhang, H.2
Levine, A.J.3
Jin, S.4
-
77
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
DOI 10.1038/ncb1730, PII NCB1730
-
Tasdemir E, Maiuri MC, Galluzzi L, et al. Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 2008;10:676-87. (Pubitemid 351772933)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.6
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
Nannmark, U.11
Samara, C.12
Pinton, P.13
Vicencio, J.M.14
Carnuccio, R.15
Moll, U.M.16
Madeo, F.17
Paterlini-Brechot, P.18
Rizzuto, R.19
Szabadkai, G.20
Pierron, G.21
Blomgren, K.22
Tavernarakis, N.23
Codogno, P.24
Cecconi, F.25
Kroemer, G.26
more..
-
79
-
-
53649086181
-
Mutant p53 protein localized in the cytoplasm inhibits autophagy
-
Morselli E, Tasdemir E, Maiuri MC, et al. Mutant p53 protein localized in the cytoplasm inhibits autophagy. Cell Cycle 2008;7: 3056-61.
-
(2008)
Cell Cycle
, vol.7
, pp. 3056-3061
-
-
Morselli, E.1
Tasdemir, E.2
Maiuri, M.C.3
-
80
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
Green DR, Kroemer G. Cytoplasmic functions of the tumour suppressor p53. Nature 2009;458:1127-30.
-
(2009)
Nature
, vol.458
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
82
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
DOI 10.1016/j.cell.2005.07.002, PII S0092867405006926
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005;122:927-39. (Pubitemid 41345209)
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Xiao, H.L.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
83
-
-
48249087666
-
Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells
-
Akar U, Chaves-Reyez A, Barria M, et al. Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells. Autophagy 2008;4:669-79.
-
(2008)
Autophagy
, vol.4
, pp. 669-679
-
-
Akar, U.1
Chaves-Reyez, A.2
Barria, M.3
-
85
-
-
33645944960
-
Autophagy and cancer therapy
-
Kondo Y, Kondo S. Autophagy and cancer therapy. Autophagy 2006;2:85-90.
-
(2006)
Autophagy
, vol.2
, pp. 85-90
-
-
Kondo, Y.1
Kondo, S.2
-
86
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
DOI 10.1038/sj.onc.1207521
-
Gozuacik D, Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 2004;23:2891-906. (Pubitemid 38638851)
-
(2004)
Oncogene
, vol.23
, Issue.16 REV. ISS. 2
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
87
-
-
27644514227
-
Another way to die: Autophagic programmed cell death
-
DOI 10.1038/sj.cdd.4401777, PII 4401777
-
Tsujimoto Y, Shimizu S. Another way to die: autophagic programmed cell death. Cell Death Differ 2005;12 (Suppl 2):1528-34. (Pubitemid 41553989)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.SUPPL. 2
, pp. 1528-1534
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
88
-
-
77957875453
-
Rhabdastrellic acid-A induced autophagy-associated cell death through blocking Akt pathway in human cancer cells
-
Li DD, Guo JF, Huang JJ, et al. Rhabdastrellic acid-A induced autophagy-associated cell death through blocking Akt pathway in human cancer cells. PLoS One 2010;5:e12176.
-
(2010)
PLoS One
, vol.5
-
-
Li, D.D.1
Guo, J.F.2
Huang, J.J.3
-
89
-
-
33846077612
-
Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1
-
DOI 10.1016/j.leukres.2006.06.021, PII S0145212606002475
-
Qian W, Liu J, Jin J, et al. Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1. Leuk Res 2007;31:329-39. (Pubitemid 46073178)
-
(2007)
Leukemia Research
, vol.31
, Issue.3
, pp. 329-339
-
-
Qian, W.1
Liu, J.2
Jin, J.3
Ni, W.4
Xu, W.5
-
90
-
-
13944256602
-
Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3
-
DOI 10.1038/sj.onc.1208095
-
Kanzawa T, Zhang L, Xiao L, et al. Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3. Oncogene 2005;24:980-91. (Pubitemid 40313875)
-
(2005)
Oncogene
, vol.24
, Issue.6
, pp. 980-991
-
-
Kanzawa, T.1
Zhang, L.2
Xiao, L.3
Germano, I.M.4
Kondo, Y.5
Kondo, S.6
-
91
-
-
78951491924
-
Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways
-
Duan WJ, Li QS, Xia MY, et al. Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways. Biol Pharm Bull 2011;34:47-53.
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 47-53
-
-
Duan, W.J.1
Li, Q.S.2
Xia, M.Y.3
-
92
-
-
79952696802
-
Zoledronic acid induces autophagic cell death in human prostate cancer cells
-
Lin JF, Lin YC, Lin YH, et al. Zoledronic acid induces autophagic cell death in human prostate cancer cells. J Urol 2011;185:1490-6.
-
(2011)
J Urol
, vol.185
, pp. 1490-1496
-
-
Lin, J.F.1
Lin, Y.C.2
Lin, Y.H.3
-
93
-
-
78649775152
-
Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: The cellular mechanism
-
Wang N, Feng Y, Zhu M, et al. Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism. J Cell Biochem 2010;111:1426-36.
-
(2010)
J Cell Biochem
, vol.111
, pp. 1426-1436
-
-
Wang, N.1
Feng, Y.2
Zhu, M.3
-
94
-
-
79952170983
-
Alpha-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMPactivated protein kinase pathway in glioblastoma cells
-
Chao AC, Hsu YL, Liu CK, et al. alpha-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMPactivated protein kinase pathway in glioblastoma cells. J Agric Food Chem 2011;59:2086-96.
-
(2011)
J Agric Food Chem
, vol.59
, pp. 2086-2096
-
-
Chao, A.C.1
Hsu, Y.L.2
Liu, C.K.3
-
95
-
-
78649530809
-
1,1-Bis(3′-indolyl)-1-(psubstituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer
-
Vanderlaag K, Su Y, Frankel AE, et al. 1,1-Bis(3′-indolyl)-1- (psubstituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer. BMC Cancer 2010;10:669.
-
(2010)
BMC Cancer
, vol.10
, pp. 669
-
-
Vanderlaag, K.1
Su, Y.2
Frankel, A.E.3
-
96
-
-
78249265610
-
Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells
-
Li J, Wang XL, Fang YC, et al. Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells. J Asian Nat Prod Res 2010;12:992-1000.
-
(2010)
J Asian Nat Prod Res
, vol.12
, pp. 992-1000
-
-
Li, J.1
Wang, X.L.2
Fang, Y.C.3
-
97
-
-
77957660865
-
Dasatinib induces autophagic cell death in human ovarian cancer
-
Le XF, Mao W, Lu Z, et al. Dasatinib induces autophagic cell death in human ovarian cancer. Cancer 2010;116:4980-90.
-
(2010)
Cancer
, vol.116
, pp. 4980-4990
-
-
Le Mao, X.F.W.1
Lu, Z.2
-
98
-
-
76249124608
-
Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation
-
Puissant A, Robert G, Fenouille N, et al. Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation. Cancer Res 2010;70:1042-52.
-
(2010)
Cancer Res
, vol.70
, pp. 1042-1052
-
-
Puissant, A.1
Robert, G.2
Fenouille, N.3
-
99
-
-
27144503701
-
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death
-
DOI 10.1038/sj.cdd.4401651, PII 4401651
-
Hoyer-Hansen M, Bastholm L, Mathiasen IS, et al. Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death. Cell Death Differ 2005;12:1297-309. (Pubitemid 41486100)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.10
, pp. 1297-1309
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Mathiasen, I.S.3
Elling, F.4
Jaattela, M.5
-
100
-
-
77955355798
-
Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells
-
Suh Y, Afaq F, Khan N, et al. Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells. Carcinogenesis 2010;31:1424-33.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1424-1433
-
-
Suh, Y.1
Afaq, F.2
Khan, N.3
-
101
-
-
77955496813
-
Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways
-
Mujumdar N, Mackenzie TN, Dudeja V, et al. Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways. Gastroenterology 2010;139:598-608.
-
(2010)
Gastroenterology
, vol.139
, pp. 598-608
-
-
Mujumdar, N.1
MacKenzie, T.N.2
Dudeja, V.3
-
102
-
-
17144427728
-
Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors
-
Takeuchi H, Kondo Y, Fujiwara K, et al. Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Res 2005;65:3336-46. (Pubitemid 40524618)
-
(2005)
Cancer Research
, vol.65
, Issue.8
, pp. 3336-3346
-
-
Takeuchi, H.1
Kondo, Y.2
Fujiwara, K.3
Kanzawa, T.4
Aoki, H.5
Mills, G.B.6
Kondo, S.7
-
103
-
-
42649122953
-
Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells
-
Hashimoto I, Koizumi K, Tatematsu M, et al. Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells. Eur J Cancer 2008;44:1022-9.
-
(2008)
Eur J Cancer
, vol.44
, pp. 1022-1029
-
-
Hashimoto, I.1
Koizumi, K.2
Tatematsu, M.3
-
104
-
-
2642553881
-
Regulation of an ATG7-beclin 1 program of autophaglic cell death by caspase-8
-
DOI 10.1126/science.1096645
-
Yu L, Alva A, Su H, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004;304:1500-2. (Pubitemid 38720930)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1500-1502
-
-
Yu, L.1
Alva, A.2
Su, H.3
Dutt, P.4
Freundt, E.5
Welsh, S.6
Baehrecke, E.H.7
Lenardo, M.J.8
-
105
-
-
38549083274
-
Eupalinin A isolated from Eupatorium chinense L. induces autophagocytosis in human leukemia HL60 cells
-
DOI 10.1016/j.bmc.2007.10.033, PII S0968089607009030
-
Itoh T, Ito Y, Ohguchi K, et al. Eupalinin A isolated from Eupatorium chinense L. induces autophagocytosis in human leukemia HL60 cells. Bioorg Med Chem 2008;16:721-31. (Pubitemid 351163064)
-
(2008)
Bioorganic and Medicinal Chemistry
, vol.16
, Issue.2
, pp. 721-731
-
-
Itoh, T.1
Ito, Y.2
Ohguchi, K.3
Ohyama, M.4
Iinuma, M.5
Otsuki, Y.6
Nozawa, Y.7
Akao, Y.8
-
106
-
-
73649093448
-
Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell
-
Xiong HY, Guo XL, Bu XX, et al. Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell. Cancer Lett 2010;288:68-74.
-
(2010)
Cancer Lett
, vol.288
, pp. 68-74
-
-
Xiong, H.Y.1
Guo, X.L.2
Bu, X.X.3
-
107
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptopic programmed cell death dependent on autophagy genes
-
DOI 10.1038/ncb1192
-
Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004;6:1221-8. (Pubitemid 39625121)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.12
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
108
-
-
79953054421
-
Strategies to improve radiotherapy with targeted drugs
-
Begg AC, Stewart FA, Vens C. Strategies to improve radiotherapy with targeted drugs. Nat Rev Cancer 2011;11:239-53.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 239-253
-
-
Begg, A.C.1
Stewart, F.A.2
Vens, C.3
-
109
-
-
80051706047
-
Autophagy inhibition contributes to radiation sensitization of esophageal squamous carcinoma cells
-
Chen YS, Song HX, Lu Y, et al. Autophagy inhibition contributes to radiation sensitization of esophageal squamous carcinoma cells. Dis Esophagus 2011;24:437-43.
-
(2011)
Dis Esophagus
, vol.24
, pp. 437-443
-
-
Chen, Y.S.1
Song, H.X.2
Lu, Y.3
-
110
-
-
21444442926
-
Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells
-
Ito H, Daido S, Kanzawa T, et al. Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells. Int J Oncol 2005;26:1401-10.
-
(2005)
Int J Oncol
, vol.26
, pp. 1401-1410
-
-
Ito, H.1
Daido, S.2
Kanzawa, T.3
-
111
-
-
79952234227
-
Autophagy inhibition enhances etoposide-induced cell death in human hepatoma G2 cells
-
Xie BS, Zhao HC, Yao SK, et al. Autophagy inhibition enhances etoposide-induced cell death in human hepatoma G2 cells. Int J Mol Med 2011;27:599-606.
-
(2011)
Int J Mol Med
, vol.27
, pp. 599-606
-
-
Xie, B.S.1
Zhao, H.C.2
Yao, S.K.3
-
112
-
-
33746326449
-
Augmentation of oridonin-induced apoptosis observed with reduced autophagy
-
DOI 10.1254/jphs.FPJ06003X
-
Cui Q, Tashiro S, Onodera S, et al. Augmentation of oridonininduced apoptosis observed with reduced autophagy. J Pharmacol Sci 2006;101:230-9. (Pubitemid 44114317)
-
(2006)
Journal of Pharmacological Sciences
, vol.101
, Issue.3
, pp. 230-239
-
-
Cui, Q.1
Tashiro, S.-I.2
Onodera, S.3
Ikejima, T.4
-
113
-
-
77957367974
-
Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies
-
Yang PM, Liu YL, Lin YC, et al. Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies. Cancer Res 2010;70:7699-709.
-
(2010)
Cancer Res
, vol.70
, pp. 7699-7709
-
-
Yang, P.M.1
Liu, Y.L.2
Lin, Y.C.3
-
114
-
-
78650835111
-
Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway
-
Vucicevic L, Misirkic M, Janjetovic K, et al. Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. Autophagy 2011;7:40-50.
-
(2011)
Autophagy
, vol.7
, pp. 40-50
-
-
Vucicevic, L.1
Misirkic, M.2
Janjetovic, K.3
-
115
-
-
77649286874
-
Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy
-
Ren JH, He WS, Nong L, et al. Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. Cancer Biother Radiopharm 2010;25:75-80.
-
(2010)
Cancer Biother Radiopharm
, vol.25
, pp. 75-80
-
-
Ren, J.H.1
He, W.S.2
Nong, L.3
-
116
-
-
33744988159
-
Autophagy: Is it cancers friend or foe?
-
Marx J. Autophagy: is it cancers friend or foe? Science 2006;312: 1160-1.
-
(2006)
Science
, vol.312
, pp. 1160-1161
-
-
Marx, J.1
|