-
1
-
-
0037050234
-
Delayed mammary gland involution in MMTV-AKT1 transgenic mice
-
Ackler, S., Ahmad, S., Tobias, C., Johnson, M.D., and Glazer, R.I. 2002. Delayed mammary gland involution in MMTV-AKT1 transgenic mice. Oncogene, 21: 198-206.
-
(2002)
Oncogene
, vol.21
, pp. 198-206
-
-
Ackler, S.1
Ahmad, S.2
Tobias, C.3
Johnson, M.D.4
Glazer, R.I.5
-
2
-
-
0001855752
-
Pathological findings in epilepsy
-
(ed. Engel, J.) (Raven Press, New York)
-
Babb T, B.W. 1987. Pathological findings in epilepsy. In Surgical Treatment of Epilepsies (ed. Engel, J.) 511-540 (Raven Press, New York).
-
(1987)
Surgical Treatment of Epilepsies
, pp. 511-540
-
-
Babb, T.B.W.1
-
3
-
-
0035733762
-
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
-
Backman, S.A., Stambolic, V., Suzuki, A., Haight, J., Elia, A., Pretorius, J., Tsao, M.S., Shannon, P., Bolon, B., Ivy, G.O., and Mak, T.W. 2001. Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Nat. Genet., 29: 396-403.
-
(2001)
Nat. Genet.
, vol.29
, pp. 396-403
-
-
Backman, S.A.1
Stambolic, V.2
Suzuki, A.3
Haight, J.4
Elia, A.5
Pretorius, J.6
Tsao, M.S.7
Shannon, P.8
Bolon, B.9
Ivy, G.O.10
Mak, T.W.11
-
4
-
-
0030980895
-
Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice
-
Bol, D.K., Kiguchi, K., Gimenez-Conti, I., Rupp, T., and DiGiovanni, J. 1997. Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice. Oncogene, 14: 1725-1734.
-
(1997)
Oncogene
, vol.14
, pp. 1725-1734
-
-
Bol, D.K.1
Kiguchi, K.2
Gimenez-Conti, I.3
Rupp, T.4
DiGiovanni, J.5
-
5
-
-
0034107671
-
Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo
-
Borlado, L.R., Redondo, C., Alvarez, B., Jimenez, C., Criado, L.M., Flores, J., Marcos, M.A., Martinez, A.C., Balomenos, D., and Carrera, A.C. 2000. Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo. Faseb J., 14: 895-903.
-
(2000)
Faseb J.
, vol.14
, pp. 895-903
-
-
Borlado, L.R.1
Redondo, C.2
Alvarez, B.3
Jimenez, C.4
Criado, L.M.5
Flores, J.6
Marcos, M.A.7
Martinez, A.C.8
Balomenos, D.9
Carrera, A.C.10
-
7
-
-
0036231778
-
Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice
-
Butler, M., McKay, R.A., Popoff, I.J., Gaarde, W.A., Witchell, D., Murray, S.F., Dean, N.M., Bhanot, S., and Monia, B.P. 2002. Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice. Diabetes, 51: 1028-1034.
-
(2002)
Diabetes
, vol.51
, pp. 1028-1034
-
-
Butler, M.1
McKay, R.A.2
Popoff, I.J.3
Gaarde, W.A.4
Witchell, D.5
Murray, S.F.6
Dean, N.M.7
Bhanot, S.8
Monia, B.P.9
-
8
-
-
85047689958
-
Cowden's disease. Association with squamous cell carcinoma of the tongue and perianal basal cell carcinoma
-
Camisa, C., Bikowski, J.B., and McDonald, S.G. 1984. Cowden's disease. Association with squamous cell carcinoma of the tongue and perianal basal cell carcinoma. Arch. Dermatol., 120: 677-678.
-
(1984)
Arch. Dermatol.
, vol.120
, pp. 677-678
-
-
Camisa, C.1
Bikowski, J.B.2
McDonald, S.G.3
-
9
-
-
0037119630
-
A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation
-
Clayton, E., Bardi, G., Bell, S.E., Chantry, D., Downes, C.P., Gray, A., Humphries, L.A., Rawlings, D., Reynolds, H., Vigorito, E., and Turner, M. 2002. A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J. Exp. Med., 196: 753-763.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 753-763
-
-
Clayton, E.1
Bardi, G.2
Bell, S.E.3
Chantry, D.4
Downes, C.P.5
Gray, A.6
Humphries, L.A.7
Rawlings, D.8
Reynolds, H.9
Vigorito, E.10
Turner, M.11
-
10
-
-
18644372367
-
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
-
Crackower, M.A., Oudit, G.Y., Kozieradzki, I., Sarao, R., Sun, H., Sasaki, T., Hirsch, E., Suzuki, A., Shioi, T., and Irie-Sasaki, J. et al. 2002. Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell, 110: 737-749.
-
(2002)
Cell
, vol.110
, pp. 737-749
-
-
Crackower, M.A.1
Oudit, G.Y.2
Kozieradzki, I.3
Sarao, R.4
Sun, H.5
Sasaki, T.6
Hirsch, E.7
Suzuki, A.8
Shioi, T.9
Irie-Sasaki, J.10
-
11
-
-
0032956396
-
The origin of marginal zone B cells in the rat
-
Dammers, P.M., de Boer, N.K., Deenen, G.J., Nieuwenhuis, P., and Kroese, F.G. 1999. The origin of marginal zone B cells in the rat. Eur. J. Immunol., 29: 1522-1531.
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 1522-1531
-
-
Dammers, P.M.1
de Boer, N.K.2
Deenen, G.J.3
Nieuwenhuis, P.4
Kroese, F.G.5
-
13
-
-
0031870959
-
Pten is essential for embryonic development and tumour suppression
-
Di Cristofano, A., Pesce, B., Cordon-Cardo, C., and Pandolfi, P.P. 1998. Pten is essential for embryonic development and tumour suppression. Nat. Genet., 19: 348-355.
-
(1998)
Nat. Genet.
, vol.19
, pp. 348-355
-
-
Di Cristofano, A.1
Pesce, B.2
Cordon-Cardo, C.3
Pandolfi, P.P.4
-
14
-
-
0034653704
-
Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion
-
DiGiovanni, J., Bol, D.K., Wilker, E., Beltran, L., Carbajal, S., Moats, S., Ramirez, A., Jorcano, J., and Kiguchi, K. 2000. Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion. Cancer Res., 60: 1561-1570.
-
(2000)
Cancer Res.
, vol.60
, pp. 1561-1570
-
-
DiGiovanni, J.1
Bol, D.K.2
Wilker, E.3
Beltran, L.4
Carbajal, S.5
Moats, S.6
Ramirez, A.7
Jorcano, J.8
Kiguchi, K.9
-
15
-
-
0027767476
-
Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas
-
Dominey, A.M., Wang, X.J., King, L.E., Jr., Nanney, L.B., Gagne, T.A., Sellheyer, K., Bundman, D.S., Longley, M.A., Rothnagel, J.A., and Greenhalgh, D.A. et al. 1993. Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas. Cell Growth Differ., 4: 1071-1082.
-
(1993)
Cell Growth Differ.
, vol.4
, pp. 1071-1082
-
-
Dominey, A.M.1
Wang, X.J.2
King L.E., Jr.3
Nanney, L.B.4
Gagne, T.A.5
Sellheyer, K.6
Bundman, D.S.7
Longley, M.A.8
Rothnagel, J.A.9
Greenhalgh, D.A.10
-
16
-
-
0024385049
-
Rapid induction of transcription of unrearranged S gamma 1 switch regions in activated murine B cells by interleukin 4
-
Esser, C. and Radbruch, A. 1989. Rapid induction of transcription of unrearranged S gamma 1 switch regions in activated murine B cells by interleukin 4. Embo J., 8: 483-488.
-
(1989)
Embo J.
, vol.8
, pp. 483-488
-
-
Esser, C.1
Radbruch, A.2
-
17
-
-
0034613222
-
T-Independent immune response: New aspects of B cell biology
-
Fagarasan, S. and Honjo, T. 2000. T-Independent immune response: new aspects of B cell biology. Science, 290: 89-92.
-
(2000)
Science
, vol.290
, pp. 89-92
-
-
Fagarasan, S.1
Honjo, T.2
-
18
-
-
0033556333
-
Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha
-
Fruman, D.A., Snapper, S.B., Yballe, C.M., Davidson, L., Yu, J.Y., Alt, F.W., and Cantley, L.C. 1999. Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha. Science, 283: 393-397.
-
(1999)
Science
, vol.283
, pp. 393-397
-
-
Fruman, D.A.1
Snapper, S.B.2
Yballe, C.M.3
Davidson, L.4
Yu, J.Y.5
Alt, F.W.6
Cantley, L.C.7
-
19
-
-
17944375813
-
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration
-
Fukui, Y., Hashimoto, O., Sanui, T., Oono, T., Koga, H., Abe, M., Inayoshi, A., Noda, M., Oike, M., Shirai, T., and Sasazuki, T. 2001. Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature, 412: 826-831.
-
(2001)
Nature
, vol.412
, pp. 826-831
-
-
Fukui, Y.1
Hashimoto, O.2
Sanui, T.3
Oono, T.4
Koga, H.5
Abe, M.6
Inayoshi, A.7
Noda, M.8
Oike, M.9
Shirai, T.10
Sasazuki, T.11
-
20
-
-
0032567078
-
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
-
Gat, U., DasGupta, R., Degenstein, L., and Fuchs, E. 1998. De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell, 95: 605-614.
-
(1998)
Cell
, vol.95
, pp. 605-614
-
-
Gat, U.1
DasGupta, R.2
Degenstein, L.3
Fuchs, E.4
-
21
-
-
0033618410
-
Multiple ras effector pathways contribute to G(1) cell cycle progression
-
Gille, H. and Downward, J. 1999. Multiple ras effector pathways contribute to G(1) cell cycle progression. J. Biol. Chem., 274: 22033-22040.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22033-22040
-
-
Gille, H.1
Downward, J.2
-
22
-
-
0035555027
-
Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses
-
Girkontaite, I., Missy, K., Sakk, V., Harenberg, A., Tedford, K., Potzel, T., Pfeffer, K., and Fischer, K.D. 2001. Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses. Nat. Immunol., 2: 855-862.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 855-862
-
-
Girkontaite, I.1
Missy, K.2
Sakk, V.3
Harenberg, A.4
Tedford, K.5
Potzel, T.6
Pfeffer, K.7
Fischer, K.D.8
-
23
-
-
0033572644
-
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway
-
Goberdhan, D.C., Paricio, N., Goodman, E.C., Mlodzik, M., and Wilson, C. 1999. Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway. Genes Dev., 13: 3244-3258.
-
(1999)
Genes Dev.
, vol.13
, pp. 3244-3258
-
-
Goberdhan, D.C.1
Paricio, N.2
Goodman, E.C.3
Mlodzik, M.4
Wilson, C.5
-
24
-
-
0027516110
-
Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene
-
Greenhalgh, D.A., Rothnagel, J.A., Quintanilla, M.I., Orengo, C.C., Gagne, T.A., Bundman, D.S., Longley, M.A., and Roop, D.R. 1993. Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol. Carcinog., 7: 99-110.
-
(1993)
Mol. Carcinog.
, vol.7
, pp. 99-110
-
-
Greenhalgh, D.A.1
Rothnagel, J.A.2
Quintanilla, M.I.3
Orengo, C.C.4
Gagne, T.A.5
Bundman, D.S.6
Longley, M.A.7
Roop, D.R.8
-
25
-
-
0032100506
-
Alterations of the MMAC1/PTEN gene in lymphoid malignancies
-
Gronbaek, K., Zeuthen, J., Guldberg, P., Ralfkiaer, E., and Hou-Jensen, K. 1998. Alterations of the MMAC1/PTEN gene in lymphoid malignancies. Blood, 91: 4388-4390.
-
(1998)
Blood
, vol.91
, pp. 4388-4390
-
-
Gronbaek, K.1
Zeuthen, J.2
Guldberg, P.3
Ralfkiaer, E.4
Hou-Jensen, K.5
-
26
-
-
0035824396
-
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
-
Groszer, M., Erickson, R., Scripture-Adams, D.D., Lesche, R., Trumpp, A., Zack, J.A., Kornblum, H.I., Liu, X., and Wu, H. 2001. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science, 294: 2186-2189.
-
(2001)
Science
, vol.294
, pp. 2186-2189
-
-
Groszer, M.1
Erickson, R.2
Scripture-Adams, D.D.3
Lesche, R.4
Trumpp, A.5
Zack, J.A.6
Kornblum, H.I.7
Liu, X.8
Wu, H.9
-
27
-
-
0034232062
-
Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response
-
Guinamard, R., Okigaki, M., Schlessinger, J., and Ravetch, J.V. 2000. Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat. Immunol., 1: 31-36.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 31-36
-
-
Guinamard, R.1
Okigaki, M.2
Schlessinger, J.3
Ravetch, J.V.4
-
28
-
-
0032558822
-
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
-
Haas-Kogan, D., Shalev, N., Wong, M., Mills, G., Yount, G., and Stokoe, D. 1998. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr. Biol., 8: 1195-1198.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1195-1198
-
-
Haas-Kogan, D.1
Shalev, N.2
Wong, M.3
Mills, G.4
Yount, G.5
Stokoe, D.6
-
29
-
-
0026668877
-
Insulin and insulino-mimetic agents induce activation of phosphatidylinositol 3′-kinase upon its association with pp185 (IRS-1) in intact rat livers
-
Hadari, Y.R., Tzahar, E., Nadiv, O., Rothenberg, P., Roberts, C.T., Jr., LeRoith, D., Yarden, Y., and Zick, Y. 1992. Insulin and insulino-mimetic agents induce activation of phosphatidylinositol 3′-kinase upon its association with pp185 (IRS-1) in intact rat livers. J. Biol. Chem., 267: 17483-17486.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17483-17486
-
-
Hadari, Y.R.1
Tzahar, E.2
Nadiv, O.3
Rothenberg, P.4
Roberts C.T., Jr.5
LeRoith, D.6
Yarden, Y.7
Zick, Y.8
-
30
-
-
0034927418
-
Cowden syndrome-diagnostic skin signs
-
Hildenbrand, C., Burgdorf, W.H., and Lautenschlager, S. 2001. Cowden syndrome-diagnostic skin signs. Dermatology, 202: 362-366.
-
(2001)
Dermatology
, vol.202
, pp. 362-366
-
-
Hildenbrand, C.1
Burgdorf, W.H.2
Lautenschlager, S.3
-
31
-
-
0026537450
-
Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors
-
Hu, P., Margolis, B., Skolnik, E.Y., Lammers, R., Ullrich, A., and Schlessinger, J. 1992. Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors. Mol. Cell Biol., 12: 981-990.
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 981-990
-
-
Hu, P.1
Margolis, B.2
Skolnik, E.Y.3
Lammers, R.4
Ullrich, A.5
Schlessinger, J.6
-
32
-
-
0033376684
-
PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development
-
Huang, H., Potter, C.J., Tao, W., Li, D.M., Brogiolo, W., Hafen, E., Sun, H., and Xu, T. 1999. PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development, 126: 5365-5372.
-
(1999)
Development
, vol.126
, pp. 5365-5372
-
-
Huang, H.1
Potter, C.J.2
Tao, W.3
Li, D.M.4
Brogiolo, W.5
Hafen, E.6
Sun, H.7
Xu, T.8
-
33
-
-
0035008874
-
Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression
-
Hutchinson, J., Jin, J., Cardiff, R.D., Woodgett, J.R., and Muller, W.J. 2001. Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression. Mol. Cell Biol., 21: 2203-2212.
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 2203-2212
-
-
Hutchinson, J.1
Jin, J.2
Cardiff, R.D.3
Woodgett, J.R.4
Muller, W.J.5
-
34
-
-
0034669945
-
Loss of PTEN expression leading to high Akt activation in human multiple myelomas
-
Hyun, T., Yam, A., Pece, S., Xie, X., Zhang, J., Miki, T., Gutkind, J.S., and Li, W. 2000. Loss of PTEN expression leading to high Akt activation in human multiple myelomas. Blood, 96: 3560-3568.
-
(2000)
Blood
, vol.96
, pp. 3560-3568
-
-
Hyun, T.1
Yam, A.2
Pece, S.3
Xie, X.4
Zhang, J.5
Miki, T.6
Gutkind, J.S.7
Li, W.8
-
35
-
-
0034658320
-
Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo
-
Jones, R.G., Parsons, M., Bonnard, M., Chan, V.S., Yeh, W.C., Woodgett, J.R., and Ohashi, P.S. 2000. Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo. J. Exp. Med., 191: 1721-1734.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1721-1734
-
-
Jones, R.G.1
Parsons, M.2
Bonnard, M.3
Chan, V.S.4
Yeh, W.C.5
Woodgett, J.R.6
Ohashi, P.S.7
-
36
-
-
0026068601
-
+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B
-
+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature, 349: 245-248.
-
(1991)
Nature
, vol.349
, pp. 245-248
-
-
Kawabe, Y.1
Ochi, A.2
-
38
-
-
0035734381
-
Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease
-
Kwon, C.H., Zhu, X., Zhang, J., Knoop, L.L., Tharp, R., Smeyne, R.J., Eberhart, C.G., Burger, P.C., and Baker, S.J. 2001. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nat. Genet., 29: 404-411.
-
(2001)
Nat. Genet.
, vol.29
, pp. 404-411
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Knoop, L.L.4
Tharp, R.5
Smeyne, R.J.6
Eberhart, C.G.7
Burger, P.C.8
Baker, S.J.9
-
39
-
-
0036714806
-
Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland
-
Li, G., Robinson, G.W., Lesche, R., Martinez-Diaz, H., Jiang, Z., Rozengurt, N., Wagner, K.U., Wu, D.C., Lane, T.F., and Liu, X. et al. 2002. Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland. Development, 129: 4159-4170.
-
(2002)
Development
, vol.129
, pp. 4159-4170
-
-
Li, G.1
Robinson, G.W.2
Lesche, R.3
Martinez-Diaz, H.4
Jiang, Z.5
Rozengurt, N.6
Wagner, K.U.7
Wu, D.C.8
Lane, T.F.9
Liu, X.10
-
40
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S.I., Puc, J., Miliaresis, C., Rodgers, L., and McCombie, R. et al. 1997. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275: 1943-1947.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
-
41
-
-
2542451142
-
Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice
-
Li, Y., Podsypanina, K., Liu, X., Crane, A., Tan, L.K., Parsons, R., and Varmus, H.E. 2001. Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice. BMC Mol. Biol., 2: 2.
-
(2001)
BMC Mol. Biol.
, vol.2
, pp. 2
-
-
Li, Y.1
Podsypanina, K.2
Liu, X.3
Crane, A.4
Tan, L.K.5
Parsons, R.6
Varmus, H.E.7
-
42
-
-
13344270890
-
Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk
-
Liao, X.C. and Littman, D.R. 1995. Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk. Immunity, 3: 757-769.
-
(1995)
Immunity
, vol.3
, pp. 757-769
-
-
Liao, X.C.1
Littman, D.R.2
-
43
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D., Marsh, D.J., Li, J., Dahia, P.L., Wang, S.I., Zheng, Z., Bose, S., Call, K.M., Tsou, H.C., and Peacocke, M. et al. 1997. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet., 16: 64-67.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
-
44
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
-
Liu, J.P., Baker, J., Perkins, A.S., Robertson, E.J., and Efstratiadis, A. 1993. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell, 75: 59-72.
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Liu, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
45
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama, T. and Dixon, J.E. 1998. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem., 273: 13375-13378.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
46
-
-
0036637660
-
PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum
-
Marino, S., Krimpenfort, P., Leung, C., van der Korput, H.A., Trapman, J., Camenisch, I., Berns, A., and Brandner, S. 2002. PTEN is essential for cell migration but not for fate determination and tumourigenesis in the cerebellum. Development, 129: 3513-3522.
-
(2002)
Development
, vol.129
, pp. 3513-3522
-
-
Marino, S.1
Krimpenfort, P.2
Leung, C.3
van der Korput, H.A.4
Trapman, J.5
Camenisch, I.6
Berns, A.7
Brandner, S.8
-
47
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
-
Marsh, D.J., Dahia, P.L., Zheng, Z., Liaw, D., Parsons, R., Gorlin, R.J., and Eng, C. 1997. Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nat. Genet., 16: 333-334.
-
(1997)
Nat. Genet.
, vol.16
, pp. 333-334
-
-
Marsh, D.J.1
Dahia, P.L.2
Zheng, Z.3
Liaw, D.4
Parsons, R.5
Gorlin, R.J.6
Eng, C.7
-
48
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y., and Honjo, T. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell, 102: 553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
49
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor suppressor function
-
Myers, M.P., Pass, I., Batty, I.H., Van der Kaay, J., Stolarov, J.P., Hemmings, B.A., Wigler, M.H., Downes, C.P., and Tonks, N.K. 1998. The lipid phosphatase activity of PTEN is critical for its tumor suppressor function. Proc. Natl. Acad. Sci. USA, 95: 13513-13518.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van der Kaay, J.4
Stolarov, J.P.5
Hemmings, B.A.6
Wigler, M.H.7
Downes, C.P.8
Tonks, N.K.9
-
50
-
-
0034681226
-
Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy
-
Naga Prasad, S.V., Esposito, G., Mao, L., Koch, W.J., and Rockman, H.A. 2000. Gbetagamma-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy. J. Biol. Chem., 275: 4693-4698.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 4693-4698
-
-
Naga Prasad, S.V.1
Esposito, G.2
Mao, L.3
Koch, W.J.4
Rockman, H.A.5
-
51
-
-
0031855499
-
Mutational analysis of the PTEN/MMAC1 gene in non-Hodgkin's lymphoma
-
Nakahara, Y., Nagai, H., Kinoshita, T., Uchida, T., Hatano, S., Murate, T., and Saito, H. 1998. Mutational analysis of the PTEN/MMAC1 gene in non-Hodgkin's lymphoma. Leukemia, 12: 1277-1280.
-
(1998)
Leukemia
, vol.12
, pp. 1277-1280
-
-
Nakahara, Y.1
Nagai, H.2
Kinoshita, T.3
Uchida, T.4
Hatano, S.5
Murate, T.6
Saito, H.7
-
52
-
-
0018136759
-
Multiple hamartoma syndrome (Cowden's disease)
-
Nuss, D.D., Aeling, J.L., Clemons, D.E., and Weber, W.N. 1978. Multiple hamartoma syndrome (Cowden's disease). Arch. Dermatol., 114: 743-746.
-
(1978)
Arch. Dermatol.
, vol.114
, pp. 743-746
-
-
Nuss, D.D.1
Aeling, J.L.2
Clemons, D.E.3
Weber, W.N.4
-
53
-
-
0037047590
-
Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice
-
Okkenhaug, K., Bilancio, A., Farjot, G., Priddle, H., Sancho, S., Peskett, E., Pearce, W., Meek, S.E., Salpekar, A., and Waterfield, M.D. et al. 2002. Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice. Science, 297: 1031-1034.
-
(2002)
Science
, vol.297
, pp. 1031-1034
-
-
Okkenhaug, K.1
Bilancio, A.2
Farjot, G.3
Priddle, H.4
Sancho, S.5
Peskett, E.6
Pearce, W.7
Meek, S.E.8
Salpekar, A.9
Waterfield, M.D.10
-
54
-
-
0035399612
-
Expression of active protein kinase B in T cells perturbs both T and B cell homeostasis and promotes inflammation
-
Parsons, M.J., Jones, R.G., Tsao, M.S., Odermatt, B., Ohashi, P.S., and Woodgett, J.R. 2001. Expression of active protein kinase B in T cells perturbs both T and B cell homeostasis and promotes inflammation. J. Immunol., 167: 42-48.
-
(2001)
J. Immunol.
, vol.167
, pp. 42-48
-
-
Parsons, M.J.1
Jones, R.G.2
Tsao, M.S.3
Odermatt, B.4
Ohashi, P.S.5
Woodgett, J.R.6
-
55
-
-
0035844886
-
Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
-
Persad, S., Troussard, A.A., McPhee, T.R., Mulholland, D.J., and Dedhar, S. 2001. Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation. J. Cell Biol., 153: 1161-1174.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1161-1174
-
-
Persad, S.1
Troussard, A.A.2
McPhee, T.R.3
Mulholland, D.J.4
Dedhar, S.5
-
56
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
Podsypanina, K., Ellenson, L.H., Nemes, A., Gu, J., Tamura, M., Yamada, K.M., Cordon-Cardo, C., Catoretti, G., Fisher, P.E., and Parsons, R. 1999. Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc. Natl. Acad. Sci. USA, 96: 1563-1568.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
Gu, J.4
Tamura, M.5
Yamada, K.M.6
Cordon-Cardo, C.7
Catoretti, G.8
Fisher, P.E.9
Parsons, R.10
-
57
-
-
0027219258
-
A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor
-
Ponzetto, C., Bardelli, A., Maina, F., Longati, P., Panayotou, G., Dhand, R., Waterfield, M.D., and Comoglio, P.M. 1993. A novel recognition motif for phosphatidylinositol 3-kinase binding mediates its association with the hepatocyte growth factor/scatter factor receptor. Mol. Cell Biol., 13: 4600-4608.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 4600-4608
-
-
Ponzetto, C.1
Bardelli, A.2
Maina, F.3
Longati, P.4
Panayotou, G.5
Dhand, R.6
Waterfield, M.D.7
Comoglio, P.M.8
-
58
-
-
0026666371
-
Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells
-
Raffioni, S. and Bradshaw, R.A. 1992. Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells. Proc. Natl. Acad. Sci. USA, 89: 9121-9125.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9121-9125
-
-
Raffioni, S.1
Bradshaw, R.A.2
-
59
-
-
0029851189
-
Altered expression of insulin-like growth factor I and its receptor during multistage carcinogenesis in mouse skin
-
Rho, O., Bol, D.K., You, J., Beltran, L., Rupp, T., and DiGiovanni, J. 1996. Altered expression of insulin-like growth factor I and its receptor during multistage carcinogenesis in mouse skin. Mol. Carcinog., 17: 62-69.
-
(1996)
Mol. Carcinog.
, vol.17
, pp. 62-69
-
-
Rho, O.1
Bol, D.K.2
You, J.3
Beltran, L.4
Rupp, T.5
DiGiovanni, J.6
-
60
-
-
0034635264
-
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
-
Sasaki, T., Irie-Sasaki, J., Jones, R.G., Oliveira-dos-Santos, A.J., Stanford, W.L., Bolon, B., Wakeham, A., Itie, A., Bouchard, D., and Kozieradzki, I. 2000. Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration. Science, 287: 1040-1046.
-
(2000)
Science
, vol.287
, pp. 1040-1046
-
-
Sasaki, T.1
Irie-Sasaki, J.2
Jones, R.G.3
Oliveira-dos-Santos, A.J.4
Stanford, W.L.5
Bolon, B.6
Wakeham, A.7
Itie, A.8
Bouchard, D.9
Kozieradzki, I.10
-
61
-
-
0034680008
-
The conserved PI3′K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila
-
Scanga, S.E., Ruel, L., Binari, R.C., Snow, B., Stambolic, V., Bouchard, D., Peters, M., Calvieri, B., Mak, T.W., Woodgett, J.R., and Manoukian, A.S. 2000. The conserved PI3′K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila. Oncogene, 19: 3971-3977.
-
(2000)
Oncogene
, vol.19
, pp. 3971-3977
-
-
Scanga, S.E.1
Ruel, L.2
Binari, R.C.3
Snow, B.4
Stambolic, V.5
Bouchard, D.6
Peters, M.7
Calvieri, B.8
Mak, T.W.9
Woodgett, J.R.10
Manoukian, A.S.11
-
62
-
-
0035929596
-
The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival
-
Schwartzbauer, G. and Robbins, J. 2001. The tumor suppressor gene PTEN can regulate cardiac hypertrophy and survival. J. Biol. Chem., 276: 35786-35793.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35786-35793
-
-
Schwartzbauer, G.1
Robbins, J.2
-
63
-
-
0034987031
-
Mammary gland involution is delayed by activated Akt in transgenic mice
-
Schwertfeger, K.L., Richert, M.M., and Anderson, S.M. 2001. Mammary gland involution is delayed by activated Akt in transgenic mice. Mol. Endocrinol., 15: 867-881.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 867-881
-
-
Schwertfeger, K.L.1
Richert, M.M.2
Anderson, S.M.3
-
64
-
-
0037012011
-
Functional roles of Akt signaling in mouse skin tumorigenesis
-
Segrelles, C., Ruiz, S., Perez, P., Murga, C., Santos, M., Budunova, I.V., Martinez, J., Larcher, F., Slaga, T.J., and Gutkind, J.S. et al. 2002. Functional roles of Akt signaling in mouse skin tumorigenesis. Oncogene, 21: 53-64.
-
(2002)
Oncogene
, vol.21
, pp. 53-64
-
-
Segrelles, C.1
Ruiz, S.2
Perez, P.3
Murga, C.4
Santos, M.5
Budunova, I.V.6
Martinez, J.7
Larcher, F.8
Slaga, T.J.9
Gutkind, J.S.10
-
65
-
-
0033811659
-
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
-
Shan, X., Czar, M.J., Bunnell, S.C., Liu, P., Liu, Y., Schwartzberg, P.L., and Wange, R.L. 2000. Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol. Cell Biol., 20: 6945-6957.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 6945-6957
-
-
Shan, X.1
Czar, M.J.2
Bunnell, S.C.3
Liu, P.4
Liu, Y.5
Schwartzberg, P.L.6
Wange, R.L.7
-
66
-
-
0032740314
-
Commitment to the CD4 lineage mediated by extracellular signal-related kinase mitogen-activated protein kinase and lck signaling
-
Sharp, L.L. and Hedrick, S.M. 1999. Commitment to the CD4 lineage mediated by extracellular signal-related kinase mitogen-activated protein kinase and lck signaling. J. Immunol., 163: 6598-6605.
-
(1999)
J. Immunol.
, vol.163
, pp. 6598-6605
-
-
Sharp, L.L.1
Hedrick, S.M.2
-
67
-
-
0036200937
-
Akt/protein kinase B promotes organ growth in transgenic mice
-
Shioi, T., McMullen, J.R., Kang, P.M., Douglas, P.S., Obata, T., Franke, T.F., Cantley, L.C., and Izumo, S. 2002. Akt/protein kinase B promotes organ growth in transgenic mice. Mol. Cell Biol., 22: 2799-2809.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 2799-2809
-
-
Shioi, T.1
McMullen, J.R.2
Kang, P.M.3
Douglas, P.S.4
Obata, T.5
Franke, T.F.6
Cantley, L.C.7
Izumo, S.8
-
68
-
-
0034697962
-
The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development
-
Sibilia, M., Fleischmann, A., Behrens, A., Stingl, L., Carroll, J., Watt, F.M., Schlessinger, J., and Wagner, E.F. 2000. The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development. Cell, 102: 211-220.
-
(2000)
Cell
, vol.102
, pp. 211-220
-
-
Sibilia, M.1
Fleischmann, A.2
Behrens, A.3
Stingl, L.4
Carroll, J.5
Watt, F.M.6
Schlessinger, J.7
Wagner, E.F.8
-
69
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic, V., Suzuki, A., de la Pompa, J.L., Brothers, G.M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J.M., Siderovski, D.P., and Mak, T.W. 1998. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell, 95: 29-39.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
de la Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
71
-
-
0030887632
-
The Gbg sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101
-
Stephens, L.R., Eguinoa, A., Erdjument-Bromage, H., Lui, M., Cooke, F., Coadwell, J., Smrcka, A.S., Thelen, M., Cadwallader, K., Tempst, P., and Hawkins, P.T. 1997. The Gbg sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101. Cell, 89: 105-114.
-
(1997)
Cell
, vol.89
, pp. 105-114
-
-
Stephens, L.R.1
Eguinoa, A.2
Erdjument-Bromage, H.3
Lui, M.4
Cooke, F.5
Coadwell, J.6
Smrcka, A.S.7
Thelen, M.8
Cadwallader, K.9
Tempst, P.10
Hawkins, P.T.11
-
72
-
-
0029090212
-
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
-
Stoyanov, B., Volinia, S., Hanck, T., Rubio, I., Loubtchenkov, M., Malek, D., Stoyanova, S., Vanhaesebroeck, B., Dhand, R., and Nurnberg, B. 1995. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science, 269: 690-693.
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
Volinia, S.2
Hanck, T.3
Rubio, I.4
Loubtchenkov, M.5
Malek, D.6
Stoyanova, S.7
Vanhaesebroeck, B.8
Dhand, R.9
Nurnberg, B.10
-
73
-
-
0037309972
-
Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation
-
in revision
-
Suzuki, A., Itami, S., Ohishi, M., Yamaguchi, M.T., Hamada, K., Inoue, T., Komazawa, N., Senoo, H., Sasaki, T., Takeda, J., Manabe, M., Mak, T.W., and Nakano, T. 2003 in revision. Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation. Cancer Res., 63: 674-681.
-
(2003)
Cancer Res.
, vol.63
, pp. 674-681
-
-
Suzuki, A.1
Itami, S.2
Ohishi, M.3
Yamaguchi, M.T.4
Hamada, K.5
Inoue, T.6
Komazawa, N.7
Senoo, H.8
Sasaki, T.9
Takeda, J.10
Manabe, M.11
Mak, T.W.12
Nakano, T.13
-
74
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
Suzuki, A., de la Pompa, J.L., Stambolic, V., Elia, A.J., Sasaki, T., del Barco Barrantes, I., Ho, A., Wakeham, A., Itie, A., and Khoo, W. et al. 1998. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr. Biol., 8: 1169-1178.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
de la Pompa, J.L.2
Stambolic, V.3
Elia, A.J.4
Sasaki, T.5
del Barco Barrantes, I.6
Ho, A.7
Wakeham, A.8
Itie, A.9
Khoo, W.10
-
75
-
-
0037416216
-
Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination
-
in press
-
Suzuki, A., Kaisho, T., Ohishi, M., Tsukio-Yamguchi, M., Tsubata, T., Koni, P.A., Sasaki, T., Mak, T.W., and Nakano, T. 2003. Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. J. Exp. Med, in press.
-
(2003)
J. Exp. Med.
-
-
Suzuki, A.1
Kaisho, T.2
Ohishi, M.3
Tsukio-Yamguchi, M.4
Tsubata, T.5
Koni, P.A.6
Sasaki, T.7
Mak, T.W.8
Nakano, T.9
-
76
-
-
0034995242
-
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
-
Suzuki, A., Yamaguchi, M.T., Ohteki, T., Sasaki, T., Kaisho, T., Kimura, Y., Yoshida, R., Wakeham, A., Higuchi, T., and Fukumoto, M. et al. 2001. T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity, 14: 523-534.
-
(2001)
Immunity
, vol.14
, pp. 523-534
-
-
Suzuki, A.1
Yamaguchi, M.T.2
Ohteki, T.3
Sasaki, T.4
Kaisho, T.5
Kimura, Y.6
Yoshida, R.7
Wakeham, A.8
Higuchi, T.9
Fukumoto, M.10
-
77
-
-
0033555829
-
Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase
-
Suzuki, H., Terauchi, Y., Fujiwara, M., Aizawa, S., Yazaki, Y., Kadowaki, T., and Koyasu, S. 1999. Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase. Science, 283: 390-392.
-
(1999)
Science
, vol.283
, pp. 390-392
-
-
Suzuki, H.1
Terauchi, Y.2
Fujiwara, M.3
Aizawa, S.4
Yazaki, Y.5
Kadowaki, T.6
Koyasu, S.7
-
78
-
-
0030992837
-
Signalling through the lipid products of phosphoinositide-3-OH kinase
-
Toker, A. and Cantley, L.C. 1997. Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature, 387: 673-676.
-
(1997)
Nature
, vol.387
, pp. 673-676
-
-
Toker, A.1
Cantley, L.C.2
-
79
-
-
0024162530
-
Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
-
Tsukamoto, A.S., Grosschedl, R., Guzman, R.C., Parslow, T., and Varmus, H.E. 1988. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell, 55: 619-625.
-
(1988)
Cell
, vol.55
, pp. 619-625
-
-
Tsukamoto, A.S.1
Grosschedl, R.2
Guzman, R.C.3
Parslow, T.4
Varmus, H.E.5
-
80
-
-
0034682763
-
Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells
-
Valentinis, B., Navarro, M., Zanocco-Marani, T., Edmonds, P., McCormick, J., Morrione, A., Sacchi, A., Romano, G., Reiss, K., and Baserga, R. 2000. Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells. J. Biol. Chem., 275: 25451-25459.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25451-25459
-
-
Valentinis, B.1
Navarro, M.2
Zanocco-Marani, T.3
Edmonds, P.4
McCormick, J.5
Morrione, A.6
Sacchi, A.7
Romano, G.8
Reiss, K.9
Baserga, R.10
-
81
-
-
0025876488
-
Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation
-
Vassar, R. and Fuchs, E. 1991. Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation. Genes Dev, 5: 714-27.
-
(1991)
Genes Dev.
, vol.5
, pp. 714-727
-
-
Vassar, R.1
Fuchs, E.2
-
82
-
-
0026668643
-
Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis
-
Vassar, R., Hutton, M.E., and Fuchs, E. 1992. Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis. Mol. Cell Biol., 12: 4643-4653.
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 4643-4653
-
-
Vassar, R.1
Hutton, M.E.2
Fuchs, E.3
-
83
-
-
0001908531
-
Cowen disease and dysplastic gangliocytoma of the cerebellum/Lhermitte-Duclos disease
-
(eds. Kleihues, P. & Cavenee, W.K.) (IARC Press, Lyon)
-
Wiestler, O.D., Padberg, G.W., and Steck, P.A. 2000. Cowen disease and dysplastic gangliocytoma of the cerebellum/Lhermitte-Duclos disease. In Pathology and Genetics of Tumors of the Nervous System (eds. Kleihues, P. & Cavenee, W.K.) 235-237 (IARC Press, Lyon).
-
(2000)
Pathology and Genetics of Tumors of the Nervous System
, pp. 235-237
-
-
Wiestler, O.D.1
Padberg, G.W.2
Steck, P.A.3
-
84
-
-
0026566156
-
Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor
-
Yamamoto, K., Lapetina, E.G., and Moxham, C.P. 1992. Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor. Endocrinology, 130: 1490-1498.
-
(1992)
Endocrinology
, vol.130
, pp. 1490-1498
-
-
Yamamoto, K.1
Lapetina, E.G.2
Moxham, C.P.3
-
85
-
-
0022653770
-
High incidence of amplification of the epidermal growth factor receptor gene in human squamous carcinoma cell lines
-
Yamamoto, T., Kamata, N., Kawano, H., Shimizu, S., Kuroki, T., Toyoshima, K., Rikimaru, K., Nomura, N., Ishizaki, R., and Pastan, I. et al. 1986. High incidence of amplification of the epidermal growth factor receptor gene in human squamous carcinoma cell lines. Cancer Res., 46: 414-416.
-
(1986)
Cancer Res.
, vol.46
, pp. 414-416
-
-
Yamamoto, T.1
Kamata, N.2
Kawano, H.3
Shimizu, S.4
Kuroki, T.5
Toyoshima, K.6
Rikimaru, K.7
Nomura, N.8
Ishizaki, R.9
Pastan, I.10
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