1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer

BMC Cancer

Volumn 10, Issue , 2010, Pages

  Vanderlaag, Kathy ^a   Su, Yunpeng ^b   Frankel, Arthur E ^b   Burghardt, Robert C ^a   Barhoumi, Rola ^a   Chadalapaka, Gayathri ^a   Jutooru, Indira ^a   Safe, Stephen ^a,c  

^a TEXAS A AND M UNIVERSITY   (United States)

^b SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1 BIS(3' INDOLYL) 1 (4 SUBSTITUTED PHENYL)METHANE DERIVATIVE; ANTINEOPLASTIC AGENT; BECLIN 1; CASPASE INHIBITOR; CELL MEMBRANE PROTEIN; ESTROGEN RECEPTOR; LACTATE DEHYDROGENASE; LIGHT CHAIN ASSOCIATED PROTEIN 3; PROTEIN BCL 2; UNCLASSIFIED DRUG; 1,1 BIS(3' INDOLYL) 1 (4 BIPHENYL)METHANE; 1,1 BIS(3' INDOLYL) 1 (4 T BUTYLPHENYL)METHANE; 1,1-BIS(3'-INDOLYL)-1-(4-BIPHENYL)METHANE; 1,1-BIS(3'-INDOLYL)-1-(4-T-BUTYLPHENYL)METHANE; APOPTOSIS REGULATORY PROTEIN; BAFILOMYCIN A1; BECN1 PROTEIN, HUMAN; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CASPASE; CYSTEINE PROTEINASE INHIBITOR; HYBRID PROTEIN; INDOLE DERIVATIVE; MACROLIDE; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PEPTIDE CHLOROMETHYL KETONE; TUMOR MARKER;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CELL DEATH; CELL LEVEL; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME RELEASE; HUMAN; HUMAN CELL; PHAGOSOME; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; TRANSIENT TRANSFECTION; ANIMAL; BAGG ALBINO MOUSE; BREAST TUMOR; CELL PROLIFERATION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG SCREENING; FEMALE; GENETIC TRANSFECTION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE; NECROSIS; NUDE MOUSE; PATHOLOGY; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOTTING, WESTERN; BREAST NEOPLASMS; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CYSTEINE PROTEINASE INHIBITORS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; L-LACTATE DEHYDROGENASE; MACROLIDES; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; NECROSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; TIME FACTORS; TRANSFECTION; TUMOR MARKERS, BIOLOGICAL; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 78649530809     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-669     Document Type: Article

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