-
1
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky D.J., Emr S.D. Autophagy as a regulated pathway of cellular degradation. Science. 290:2000;1717-1721.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
2
-
-
0035286734
-
Molecular dissection of autophagy: Two ubiquitin-like systems
-
Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat. Rev. Mol. Cell. Biol. 2:2001;211-216.
-
(2001)
Nat. Rev. Mol. Cell. Biol.
, vol.2
, pp. 211-216
-
-
Ohsumi, Y.1
-
4
-
-
0035911162
-
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
-
Mizushima N., Yamamoto A., Hatano M., Kobayashi Y., Kabeya Y., Suzuki K., Tokuhisa T., Ohsumi Y., Yoshimori T. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J. Cell Biol. 152:2001;657-667.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 657-667
-
-
Mizushima, N.1
Yamamoto, A.2
Hatano, M.3
Kobayashi, Y.4
Kabeya, Y.5
Suzuki, K.6
Tokuhisa, T.7
Ohsumi, Y.8
Yoshimori, T.9
-
5
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y., Mizushima N., Ueno T., Yamamoto A., Kirisako T., Noda T., Kominami E., Ohsumi Y., Yoshimori T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 19:2000;5720-5728.
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Kominami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
6
-
-
0027424777
-
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
-
Tsukada M., Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 333:1993;169-174.
-
(1993)
FEBS Lett.
, vol.333
, pp. 169-174
-
-
Tsukada, M.1
Ohsumi, Y.2
-
7
-
-
0027730391
-
Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)phthalate treatment. II. Immunocytochemical analysis of early and late autophagosomes
-
Yokota S., Himeno M., Roth J., Brada D., Kato K. Formation of autophagosomes during degradation of excess peroxisomes induced by di-(2-ethylhexyl)phthalate treatment. II. Immunocytochemical analysis of early and late autophagosomes. Eur. J. Cell Biol. 62:1993;372-383.
-
(1993)
Eur. J. Cell Biol.
, vol.62
, pp. 372-383
-
-
Yokota, S.1
Himeno, M.2
Roth, J.3
Brada, D.4
Kato, K.5
-
8
-
-
0023202836
-
Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver
-
Masaki R., Yamamoto A., Tashiro Y. Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver. J. Cell Biol. 104:1987;1207-1215.
-
(1987)
J. Cell Biol.
, vol.104
, pp. 1207-1215
-
-
Masaki, R.1
Yamamoto, A.2
Tashiro, Y.3
-
9
-
-
0035487007
-
The mitochondrial permeability transition initiates autophagy in rat hepatocytes
-
Elmore S.P., Qian T., Grissom S.F., Lemasters J.J. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. FASEB J. 15:2001;2286-2287.
-
(2001)
FASEB J.
, vol.15
, pp. 2286-2287
-
-
Elmore, S.P.1
Qian, T.2
Grissom, S.F.3
Lemasters, J.J.4
-
11
-
-
0028899789
-
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
-
Blommaart E.F., Luiken J.J., Blommaart P.J., van Woerkom G.M., Meijer A.J. Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270:1995;2320-2326.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2320-2326
-
-
Blommaart, E.F.1
Luiken, J.J.2
Blommaart, P.J.3
Van Woerkom, G.M.4
Meijer, A.J.5
-
12
-
-
0032512636
-
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
-
Noda T., Ohsumi Y. Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J. Biol. Chem. 273:1998;3963-3966.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3963-3966
-
-
Noda, T.1
Ohsumi, Y.2
-
13
-
-
0345856413
-
Insulin-dependent signaling regulated azurophil granule-selective macroautophagy in human myeloblastic cells
-
in press, published online September 3, 2003 before print
-
K. Saeki, Z. Hong, M. Nakatsu, T. Yoshimori, Y. Kabeya, A. Yamamoto, Y. Kaburagi, A. Yuo, Insulin-dependent signaling regulated azurophil granule-selective macroautophagy in human myeloblastic cells, J. Leukoc. Biol. (2003), in press, published online September 3, 2003 before print.
-
(2003)
J. Leukoc. Biol.
-
-
Saeki, K.1
Hong, Z.2
Nakatsu, M.3
Yoshimori, T.4
Kabeya, Y.5
Yamamoto, A.6
Kaburagi, Y.7
Yuo, A.8
-
14
-
-
0034703021
-
Leucine limitation induces autophagy and activation of lysosome-dependent proteolysis in C2C12 myotubes through a mammalian target of rapamycin-independent signaling pathway
-
Mordier S., Deval C., Bechet D., Tassa A., Ferrara M. Leucine limitation induces autophagy and activation of lysosome-dependent proteolysis in C2C12 myotubes through a mammalian target of rapamycin-independent signaling pathway. J. Biol. Chem. 275:2000;29900-29906.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29900-29906
-
-
Mordier, S.1
Deval, C.2
Bechet, D.3
Tassa, A.4
Ferrara, M.5
-
15
-
-
0028107099
-
De novo autophagic vacuole formation in hepatocytes permeabilized by Staphylococcus aureus alpha-toxin. Inhibition by nonhydrolyzable GTP analogs
-
Kadowaki M., Venerando R., Miotto G., Mortimore G.E. De novo autophagic vacuole formation in hepatocytes permeabilized by Staphylococcus aureus alpha-toxin. Inhibition by nonhydrolyzable GTP analogs. J. Biol. Chem. 269:1994;3703-3710.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3703-3710
-
-
Kadowaki, M.1
Venerando, R.2
Miotto, G.3
Mortimore, G.E.4
-
16
-
-
0028985249
-
A heterotrimeric Gi3-protein controls autophagic sequestration in the human colon cancer cell line HT-29
-
Ogier-Denis E., Couvineau A., Maoret J.J., Houri J.J., Bauvy C., De Stefanis D., Isidoro C., Laburthe M., Codogno P. A heterotrimeric Gi3-protein controls autophagic sequestration in the human colon cancer cell line HT-29. J. Biol. Chem. 270:1995;13-16.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13-16
-
-
Ogier-Denis, E.1
Couvineau, A.2
Maoret, J.J.3
Houri, J.J.4
Bauvy, C.5
De Stefanis, D.6
Isidoro, C.7
Laburthe, M.8
Codogno, P.9
-
17
-
-
0001488499
-
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
-
Liang X.H., Kleeman L.K., Jiang H.H., Gordon G., Goldman J.E., Berry G., Herman B., Levine B. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J. Virol. 72:1998;8586-8596.
-
(1998)
J. Virol.
, vol.72
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
Gordon, G.4
Goldman, J.E.5
Berry, G.6
Herman, B.7
Levine, B.8
-
18
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang X.H., Jackson S., Seaman M., Brown K., Kempkes B., Hibshoosh H., Levine B. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature. 402:1999;672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
19
-
-
0035032723
-
Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
-
Kihara A., Kabeya Y., Ohsumi Y., Yoshimori T. Beclin- phosphatidylinositol 3-kinase complex functions at the trans-Golgi network. EMBO Rep. 2:2001;330-335.
-
(2001)
EMBO Rep.
, vol.2
, pp. 330-335
-
-
Kihara, A.1
Kabeya, Y.2
Ohsumi, Y.3
Yoshimori, T.4
-
20
-
-
0035809160
-
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
-
Kihara A., Noda T., Ishihara N., Ohsumi Y. Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J. Cell Biol. 152:2001;519-530.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 519-530
-
-
Kihara, A.1
Noda, T.2
Ishihara, N.3
Ohsumi, Y.4
-
21
-
-
0025362656
-
In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome
-
Tooze J., Hollinshead M., Ludwig T., Howell K., Hoflack B., Kern H. In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome. J. Cell Biol. 111:1990;329-345.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 329-345
-
-
Tooze, J.1
Hollinshead, M.2
Ludwig, T.3
Howell, K.4
Hoflack, B.5
Kern, H.6
-
22
-
-
0028856914
-
Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: Effects of vinblastine and asparagine on vacuole distributions
-
Fengsrud M., Roos N., Berg T., Liou W., Slot J.W., Seglen P.O. Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions. Exp. Cell Res. 221:1995;504-519.
-
(1995)
Exp. Cell Res.
, vol.221
, pp. 504-519
-
-
Fengsrud, M.1
Roos, N.2
Berg, T.3
Liou, W.4
Slot, J.W.5
Seglen, P.O.6
-
23
-
-
0031031041
-
The autophagic and endocytic pathways converge at the nascent autophagic vacuoles
-
Liou W., Geuze H.J., Geelen M.J., Slot J.W. The autophagic and endocytic pathways converge at the nascent autophagic vacuoles. J. Cell Biol. 136:1997;61-70.
-
(1997)
J. Cell Biol.
, vol.136
, pp. 61-70
-
-
Liou, W.1
Geuze, H.J.2
Geelen, M.J.3
Slot, J.W.4
-
24
-
-
0036253107
-
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation
-
Nara A., Mizushima N., Yamamoto A., Kabeya Y., Ohsumi Y., Yoshimori T. SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation. Cell Struct. Funct. 27:2002;29-37.
-
(2002)
Cell Struct. Funct.
, vol.27
, pp. 29-37
-
-
Nara, A.1
Mizushima, N.2
Yamamoto, A.3
Kabeya, Y.4
Ohsumi, Y.5
Yoshimori, T.6
-
25
-
-
0033994538
-
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells
-
Yoshimori T., Yamagata F., Yamamoto A., Mizushima N., Kabeya Y., Nara A., Miwako I., Ohashi M., Ohsumi M., Ohsumi Y. The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells. Mol. Biol. Cell. 11:2000;747-763.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 747-763
-
-
Yoshimori, T.1
Yamagata, F.2
Yamamoto, A.3
Mizushima, N.4
Kabeya, Y.5
Nara, A.6
Miwako, I.7
Ohashi, M.8
Ohsumi, M.9
Ohsumi, Y.10
-
26
-
-
0037439880
-
A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: Class e vps phenotype in mammalian cells
-
Fujita H., Yamanaka M., Imamura K., Tanaka Y., Nara A., Yoshimori T., Yokota S., Himeno M. A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: class E vps phenotype in mammalian cells. J. Cell Sci. 116:2003;401-414.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 401-414
-
-
Fujita, H.1
Yamanaka, M.2
Imamura, K.3
Tanaka, Y.4
Nara, A.5
Yoshimori, T.6
Yokota, S.7
Himeno, M.8
-
27
-
-
0032563798
-
A protein conjugation system essential for autophagy
-
Mizushima N., Noda T., Yoshimori T., Tanaka Y., Ishii T., George M.D., Klionsky D.J., Ohsumi M., Ohsumi Y. A protein conjugation system essential for autophagy. Nature. 395:1998;395-398.
-
(1998)
Nature
, vol.395
, pp. 395-398
-
-
Mizushima, N.1
Noda, T.2
Yoshimori, T.3
Tanaka, Y.4
Ishii, T.5
George, M.D.6
Klionsky, D.J.7
Ohsumi, M.8
Ohsumi, Y.9
-
28
-
-
0032545292
-
A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy
-
Mizushima N., Sugita H., Yoshimori T., Ohsumi Y. A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy. J. Biol. Chem. 273:1998;33889-33892.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33889-33892
-
-
Mizushima, N.1
Sugita, H.2
Yoshimori, T.3
Ohsumi, Y.4
-
29
-
-
0028289946
-
Molecular characterization of light chain 3
-
Mann S.S., Hammarback J.A. Molecular characterization of light chain 3. J. Biol. Chem. 269:1994;11492-11497.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 11492-11497
-
-
Mann, S.S.1
Hammarback, J.A.2
-
30
-
-
0038325675
-
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
-
Mizushima N., Kuma A., Kobayashi Y., Yamamoto A., Matsubae M., Takao T., Natsume T., Ohsumi Y., Yoshimori T. Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J. Cell Sci. 116:2003;1679-1688.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1679-1688
-
-
Mizushima, N.1
Kuma, A.2
Kobayashi, Y.3
Yamamoto, A.4
Matsubae, M.5
Takao, T.6
Natsume, T.7
Ohsumi, Y.8
Yoshimori, T.9
-
31
-
-
0035910423
-
The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
-
Tanida I., Tanida-Miyake E., Ueno T., Kominami E. The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3. J. Biol. Chem. 276:2001;1701-1706.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1701-1706
-
-
Tanida, I.1
Tanida-Miyake, E.2
Ueno, T.3
Kominami, E.4
-
32
-
-
0037134443
-
Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p
-
Tanida I., Tanida-Miyake E., Komatsu M., Ueno T., Kominami E. Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p. J. Biol. Chem. 277:2002;13739-13744.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13739-13744
-
-
Tanida, I.1
Tanida-Miyake, E.2
Komatsu, M.3
Ueno, T.4
Kominami, E.5
-
33
-
-
0001417555
-
GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28
-
Sagiv Y., Legesse-Miller A., Porat A., Elazar Z. GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28. EMBO J. 19:2000;1494-1504.
-
(2000)
EMBO J.
, vol.19
, pp. 1494-1504
-
-
Sagiv, Y.1
Legesse-Miller, A.2
Porat, A.3
Elazar, Z.4
-
35
-
-
0035874881
-
Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein
-
Xin Y., Yu L., Chen Z., Zheng L., Fu Q., Jiang J., Zhang P., Gong R., Zhao S. Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein. Genomics. 74:2001;408-413.
-
(2001)
Genomics
, vol.74
, pp. 408-413
-
-
Xin, Y.1
Yu, L.2
Chen, Z.3
Zheng, L.4
Fu, Q.5
Jiang, J.6
Zhang, P.7
Gong, R.8
Zhao, S.9
-
37
-
-
0025283961
-
Developmental cell death: Morphological diversity and multiple mechanisms
-
Clarke P.G. Developmental cell death: morphological diversity and multiple mechanisms. Anat. Embryol. (Berl.). 181:1990;195-213.
-
(1990)
Anat. Embryol. (Berl.)
, vol.181
, pp. 195-213
-
-
Clarke, P.G.1
-
38
-
-
0015880897
-
The morphology of various types of cell death in prenatal tissues
-
Schweichel J.U., Merker H.J. The morphology of various types of cell death in prenatal tissues. Teratology. 7:1973;253-266.
-
(1973)
Teratology
, vol.7
, pp. 253-266
-
-
Schweichel, J.U.1
Merker, H.J.2
-
39
-
-
0032971161
-
Caspase-independent programmed cell death with necrotic morphology
-
Kitanaka C., Kuchino Y. Caspase-independent programmed cell death with necrotic morphology. Cell. Death Differ. 6:1999;508-515.
-
(1999)
Cell. Death Differ.
, vol.6
, pp. 508-515
-
-
Kitanaka, C.1
Kuchino, Y.2
-
40
-
-
10744225487
-
A unified nomenclature for yeast autophagy-related genes
-
Klionsky D.J., Cregg J.M., Dunn W.A. Jr., Emr S.D., Sakai Y., Sandoval I.V., Sibirny A., Subramani S., Thumm M., Veenhuis M., Ohsumi Y. A unified nomenclature for yeast autophagy-related genes. Dev. Cell. 5:2003;539-545.
-
(2003)
Dev. Cell
, vol.5
, pp. 539-545
-
-
Klionsky, D.J.1
Cregg, J.M.2
Dunn, W.A.Jr.3
Emr, S.D.4
Sakai, Y.5
Sandoval, I.V.6
Sibirny, A.7
Subramani, S.8
Thumm, M.9
Veenhuis, M.10
Ohsumi, Y.11
|