Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1

Leukemia Research

Volumn 31, Issue 3, 2007, Pages 329-339

  Qian, Wenbin ^a,b   Liu, Junqing ^a   Jin, Jie ^a,b   Ni, Wanmao ^a,b   Xu, Weilai ^a  

^a First Affiliated Hospital   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Acute lymphocytic leukemia; Apoptosis; Arsenic trioxide; Autophagy; Myelodysplastic syndrome

Indexed keywords

3 METHYLADENINE; ARSENIC TRIOXIDE; BECLIN 1; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER INHIBITION; CELL INCLUSION; CELL PROLIFERATION; CELL VACUOLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; DRUG MECHANISM; ELECTRON MICROSCOPY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T CELL LEUKEMIA; UPREGULATION;

APOPTOSIS REGULATORY PROTEINS; ARSENICALS; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; LEUKEMIA, T-CELL; MEMBRANE PROTEINS; MYELODYSPLASTIC SYNDROMES; OXIDES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; STRUCTURE-ACTIVITY RELATIONSHIP; UP-REGULATION;

EID: 33846077612     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2006.06.021     Document Type: Article

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