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Volumn 221, Issue 2, 2010, Pages 117-124

Autophagy: Assays and artifacts

Author keywords

Analysis; Autophagic flux; Autophagy; LC3; Mechanism; Method; Process; Technique

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 METHYLADENINE; BAFILOMYCIN A1; CHLOROQUINE; EVEROLIMUS; GREEN FLUORESCENT PROTEIN; LITHIUM CHLORIDE; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE PROTEIN 1 LIGHT CHAIN 3; PEPSTATIN; PROTEIN LC3B II; RAPAMYCIN; TEMSIROLIMUS; THAPSIGARGIN; TUNICAMYCIN; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 77952766891     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2694     Document Type: Review
Times cited : (673)

References (64)
  • 1
    • 77950994646 scopus 로고    scopus 로고
    • Autophagy: Cellular and molecular mechanisms
    • DOI: 10.1002/path.2697
    • Glick D, Barth S, Macleod KF. Autophagy: cellular and molecular mechanisms. J Pathol 2010; DOI: 10.1002/path.2697.
    • (2010) J Pathol
    • Glick, D.1    Barth, S.2    Macleod, K.F.3
  • 2
    • 0000730374 scopus 로고
    • Cytoplasmic components in hepatic cell lysosomes
    • Ashford TP, Porter KR. Cytoplasmic components in hepatic cell lysosomes. J Cell Biol 1962; 12: 198-202.
    • (1962) J Cell Biol , vol.12 , pp. 198-202
    • Ashford, T.P.1    Porter, K.R.2
  • 3
    • 0014083718 scopus 로고
    • Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes
    • Deter RL, De Duve C. Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes. J Cell Biol 1967; 33: 437-449.
    • (1967) J Cell Biol , vol.33 , pp. 437-449
    • Deter, R.L.1    De Duve, C.2
  • 4
    • 84934438243 scopus 로고    scopus 로고
    • Fine structure of the autophagosome
    • Eskelinen EL. Fine structure of the autophagosome. Methods Mol Biol 2008; 445: 11-28.
    • (2008) Methods Mol Biol , vol.445 , pp. 11-28
    • Eskelinen, E.L.1
  • 7
    • 71649112895 scopus 로고    scopus 로고
    • 3D tomography reveals connections between the phagophore and endoplasmic reticulum
    • Yla-Anttila P, Vihinen H, Jokitalo E, Eskelinen EL. 3D tomography reveals connections between the phagophore and endoplasmic reticulum. Autophagy 2009; 5: 1180-1185.
    • (2009) Autophagy , vol.5 , pp. 1180-1185
    • Yla-Anttila, P.1    Vihinen, H.2    Jokitalo, E.3    Eskelinen, E.L.4
  • 8
    • 38949136372 scopus 로고    scopus 로고
    • To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells
    • Eskelinen EL. To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells. Autophagy 2008; 4: 257-260.
    • (2008) Autophagy , vol.4 , pp. 257-260
    • Eskelinen, E.L.1
  • 11
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al . LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19: 5720-5728.
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6
  • 12
    • 35848957932 scopus 로고    scopus 로고
    • Cytosolic LC3 ratio as a sensitive index of macroautophagy in isolated rat hepatocytes and H4-II-E cells
    • Karim MR, Kanazawa T, Daigaku Y, Fujimura S, Miotto G, Kadowaki M. Cytosolic LC3 ratio as a sensitive index of macroautophagy in isolated rat hepatocytes and H4-II-E cells. Autophagy 2007; 3: 553-560. (Pubitemid 350060051)
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 553-560
    • Karim, Md.R.1    Kanazawa, T.2    Daigaku, Y.3    Fujimura, S.4    Miotto, G.5    Kadowaki, M.6
  • 15
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima N. Autophagy: process and function. Genes Dev 2007; 21: 2861-2873.
    • (2007) Genes Dev , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 16
    • 67649467294 scopus 로고    scopus 로고
    • Dynamics and diversity in autophagy mechanisms: Lessons from yeast
    • Nakatogawa H, Suzuki K, Kamada Y, Ohsumi Y. Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol 2009; 10: 458-467.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 458-467
    • Nakatogawa, H.1    Suzuki, K.2    Kamada, Y.3    Ohsumi, Y.4
  • 17
    • 34447099450 scopus 로고    scopus 로고
    • Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
    • DOI 10.1016/j.cell.2007.05.021, PII S0092867407006587
    • Nakatogawa H, Ichimura Y, Ohsumi Y. Atg8, a ubiquitin-like protein required for autophagosome formation, mediated membrane tethering and hemifusion. Cell 2007; 130: 165-178. (Pubitemid 47031316)
    • (2007) Cell , vol.130 , Issue.1 , pp. 165-178
    • Nakatogawa, H.1    Ichimura, Y.2    Ohsumi, Y.3
  • 18
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N, Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 2007; 3: 542-545.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 19
    • 59349105233 scopus 로고    scopus 로고
    • Monitoring autophagy in mammalian cultured cells through the dynamics of LC3
    • Kimura S, Fujita N, Noda T, Yoshimori T. Monitoring autophagy in mammalian cultured cells through the dynamics of LC3. Methods Enzymol 2009; 452: 1-12.
    • (2009) Methods Enzymol , vol.452 , pp. 1-12
    • Kimura, S.1    Fujita, N.2    Noda, T.3    Yoshimori, T.4
  • 20
    • 53549084325 scopus 로고    scopus 로고
    • Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?
    • Klionsky DJ, Elazar Z, Seglen PO, Rubinsztein DC. Does bafilomycin A1 block the fusion of autophagosomes with lysosomes? Autophagy 2008; 4: 849-950.
    • (2008) Autophagy , vol.4 , pp. 849-950
    • Klionsky, D.J.1    Elazar, Z.2    Seglen, P.O.3    Rubinsztein, D.C.4
  • 22
    • 34548259958 scopus 로고    scopus 로고
    • P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
    • Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, et al . p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282: 24121-24145.
    • (2007) J Biol Chem , vol.282 , pp. 24121-24145
    • Pankiv, S.1    Clausen, T.H.2    Lamark, T.3    Brech, A.4    Bruun, J.A.5    Outzen, H.6
  • 24
    • 59849126863 scopus 로고    scopus 로고
    • Biochemical and morphological detection of inclusion bodies in autophagy-deficient mice
    • Waguri S, Komatsu M. Biochemical and morphological detection of inclusion bodies in autophagy-deficient mice. Methods Enzymol 2009; 453: 181-196.
    • (2009) Methods Enzymol , vol.453 , pp. 181-196
    • Waguri, S.1    Komatsu, M.2
  • 25
    • 66449114033 scopus 로고    scopus 로고
    • P62 at the crossroads of autophagy, apoptosis and cancer
    • Moscat J, Diaz-Meco MT. p62 at the crossroads of autophagy, apoptosis and cancer. Cell 2009; 137: 1001-1004.
    • (2009) Cell , vol.137 , pp. 1001-1004
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 28
    • 47049100413 scopus 로고    scopus 로고
    • Essential role for Nix in autophagic maturation of erythroid cells
    • DOI 10.1038/nature07006, PII NATURE07006
    • Sandoval H, Thiagarajan P, Dasgupta SK, Scumacker A, Prchal JT, Chen M, et al . Essential role for Nix in autophagic maturation of red cells. Nature 2008; 454: 232-235. (Pubitemid 351969889)
    • (2008) Nature , vol.454 , Issue.7201 , pp. 232-235
    • Sandoval, H.1    Thiagarajan, P.2    Dasgupta, S.K.3    Schumacher, A.4    Prchal, J.T.5    Chen, M.6    Wang, J.7
  • 29
    • 51649124519 scopus 로고    scopus 로고
    • Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
    • Kundu M, Lindsten T, Yang CY, Wu J, Zhao F, Zhang J, et al . Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood 2008; 112: 1493-1502.
    • (2008) Blood , vol.112 , pp. 1493-1502
    • Kundu, M.1    Lindsten, T.2    Yang, C.Y.3    Wu, J.4    Zhao, F.5    Zhang, J.6
  • 30
    • 43649104579 scopus 로고    scopus 로고
    • Mitochondrial autophagy is a HIF-1 dependent adaptive metabolic response to hypoxia
    • Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, et al . Mitochondrial autophagy is a HIF-1 dependent adaptive metabolic response to hypoxia. J Biol Chem 2008; 283: 10892-10903.
    • (2008) J Biol Chem , vol.283 , pp. 10892-10903
    • Zhang, H.1    Bosch-Marce, M.2    Shimoda, L.A.3    Tan, Y.S.4    Baek, J.H.5    Wesley, J.B.6
  • 31
    • 35848930800 scopus 로고    scopus 로고
    • Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3
    • Tracy K, Macleod KF. Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3. Autophagy 2007; 3: 616-619.
    • (2007) Autophagy , vol.3 , pp. 616-619
    • Tracy, K.1    Macleod, K.F.2
  • 33
    • 67650230871 scopus 로고    scopus 로고
    • Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation
    • Zhang J, Randall MS, Loyd MR, Dorsey FC, Kundu M, Cleveland JL, et al . Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation. Blood 2009; 114: 157-164.
    • (2009) Blood , vol.114 , pp. 157-164
    • Zhang, J.1    Randall, M.S.2    Loyd, M.R.3    Dorsey, F.C.4    Kundu, M.5    Cleveland, J.L.6
  • 35
    • 59249102240 scopus 로고    scopus 로고
    • Cytosolic LC3 ratio as a quantitative index of macroautophagy
    • Kadowaki M, Karim MR. Cytosolic LC3 ratio as a quantitative index of macroautophagy. Methods Enzymol 2009; 452: 199-213.
    • (2009) Methods Enzymol , vol.452 , pp. 199-213
    • Kadowaki, M.1    Karim, M.R.2
  • 36
    • 34250900953 scopus 로고    scopus 로고
    • LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: Caution in the interpretation of LC3 localization
    • Kuma A, Matsui M, Mizushima N. LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization. Autophagy 2007; 3: 323-328. (Pubitemid 46986336)
    • (2007) Autophagy , vol.3 , Issue.4 , pp. 323-328
    • Kuma, A.1    Matsui, M.2    Mizushima, N.3
  • 37
    • 34548077575 scopus 로고    scopus 로고
    • Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
    • Kimura S, Noda T, Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 2007; 3: 452-460. (Pubitemid 47293726)
    • (2007) Autophagy , vol.3 , Issue.5 , pp. 452-460
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 38
    • 34447276502 scopus 로고    scopus 로고
    • Human WIPI-1 puncta-formation: A novel assay to assess mammalian autophagy
    • DOI 10.1016/j.febslet.2007.06.040, PII S0014579307006965
    • Proikas-Cezanne T, Ruckerbauer S, Stierhof YD, Berg C, Nordheim A. Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy. FEBS Lett 2007; 581: 3396-3404. (Pubitemid 47048184)
    • (2007) FEBS Letters , vol.581 , Issue.18 , pp. 3396-3404
    • Proikas-Cezanne, T.1    Ruckerbauer, S.2    Stierhof, Y.-D.3    Berg, C.4    Nordheim, A.5
  • 39
    • 59249087428 scopus 로고    scopus 로고
    • Assaying of autophagic protein degradation
    • Bauvy C, Meijer AJ, Codogno P. Assaying of autophagic protein degradation. Methods Enzymol 2009; 452: 47-61.
    • (2009) Methods Enzymol , vol.452 , pp. 47-61
    • Bauvy, C.1    Meijer, A.J.2    Codogno, P.3
  • 40
    • 0033591236 scopus 로고    scopus 로고
    • Autolysosomal membrane-associated betaine homocysteine methyltransferase: Limited degradation fragment of a sequestered cytosolic enzyme monitoring autophagy
    • Ueno T, Ishidoh K, Mineki R, Tanida I, Murayama K, Kadowaki M, et al . Autolysosomal membrane-associated betaine homocysteine methyltransferase. Limited degradation fragment of a sequestered cytosolic enzyme monitoring autophagy. J Biol Chem 1999; 274: 15222-15229. (Pubitemid 129518862)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.21 , pp. 15222-15229
    • Ueno, T.1    Ishidoh, K.2    Mineki, R.3    Tanida, I.4    Murayama, K.5    Kadowaki, M.6    Kominami, E.7
  • 41
    • 38949146398 scopus 로고    scopus 로고
    • Macroautophagy-dependent, intralysosomal cleavage of a betaine homocysteine methyltransferase fusion protein requires stable multimerization
    • Mercer CA, Kaliappan A, Dennis PB. Macroautophagy-dependent, intralysosomal cleavage of a betaine homocysteine methyltransferase fusion protein requires stable multimerization. Autophagy 2008; 4: 185-194. (Pubitemid 351231182)
    • (2008) Autophagy , vol.4 , Issue.2 , pp. 185-194
    • Mercer, C.A.1    Kaliappan, A.2    Dennis, P.B.3
  • 42
    • 59249109653 scopus 로고    scopus 로고
    • The GST-BHMT assay and related assays for autophagy
    • Dennis PB, Mercer CA. The GST-BHMT assay and related assays for autophagy. Methods Enzymol 2009; 452: 97-118.
    • (2009) Methods Enzymol , vol.452 , pp. 97-118
    • Dennis, P.B.1    Mercer, C.A.2
  • 43
    • 0025051251 scopus 로고
    • Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes
    • DOI 10.1083/jcb.111.3.941
    • Kopitz J, Kisen GO, Gordon PB, Bohley P, Seglen PO. Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes. J Cell Biol 1990; 111: 941-953. (Pubitemid 20263777)
    • (1990) Journal of Cell Biology , vol.111 , Issue.3 , pp. 941-953
    • Kopitz, J.1    Kisen, G.O.2    Gordon, P.B.3    Bohley, P.4    Seglen, P.O.5
  • 45
    • 0027716683 scopus 로고
    • Tracing intracellular proteolytic pathways. Proteolysis of fatty acid synthase and other cytoplasmic proteins in the yeast Saccharomyces cerevisiae
    • Egner R, Thumm M, Straub M, Simeon A, Schuller HJ, Wolf DH. Tracing intracellular proteolytic pathways. Proteolysis of fatty acid synthase and other cytoplasmic proteins in the yeast Saccharomyces cerevisiae. J Biol Chem 1993; 268: 27269-27276. (Pubitemid 24006446)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.36 , pp. 27269-27276
    • Egner, R.1    Thumm, M.2    Straub, M.3    Simeon, A.4    Schuller, H.-J.5    Wolf, D.H.6
  • 46
    • 66349135140 scopus 로고    scopus 로고
    • Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters
    • Ju JS, Miller SE, Jackson E, Cadwell K, Piwnica-Worms D, Weihl CC. Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters. Autophagy 2009; 5: 511-519.
    • (2009) Autophagy , vol.5 , pp. 511-519
    • Ju, J.S.1    Miller, S.E.2    Jackson, E.3    Cadwell, K.4    Piwnica-Worms, D.5    Weihl, C.C.6
  • 47
    • 11144245626 scopus 로고    scopus 로고
    • The role of autophagy during the early neonatal starvation period
    • Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, et al . The role of autophagy during the early neonatal starvation period. Nature 2004; 432: 1032-1036.
    • (2004) Nature , vol.432 , pp. 1032-1036
    • Kuma, A.1    Hatano, M.2    Matsui, M.3    Yamamoto, A.4    Nakaya, H.5    Yoshimori, T.6
  • 48
    • 51449085299 scopus 로고    scopus 로고
    • The role of autophagy in mammalian development: Cell makeover rather than cell death
    • Cecconi F, Levine B. The role of autophagy in mammalian development: cell makeover rather than cell death. Dev Cell 2008; 15: 344-357.
    • (2008) Dev Cell , vol.15 , pp. 344-357
    • Cecconi, F.1    Levine, B.2
  • 51
    • 33847404337 scopus 로고    scopus 로고
    • Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development
    • DOI 10.1016/j.cell.2006.12.044, PII S009286740700178X
    • Qu X, Zou Z, Sun Q, Luby-Phelps K, Cheng P, Hogan RN, et al . Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 2007; 128: 931-946. (Pubitemid 46341412)
    • (2007) Cell , vol.128 , Issue.5 , pp. 931-946
    • Qu, X.1    Zou, Z.2    Sun, Q.3    Luby-Phelps, K.4    Cheng, P.5    Hogan, R.N.6    Gilpin, C.7    Levine, B.8
  • 52
    • 84934440488 scopus 로고    scopus 로고
    • Autophagosomes in GFP-LC3 transgenic mice
    • Mizushima N, Kuma A. Autophagosomes in GFP-LC3 transgenic mice. Methods Mol Biol 2008; 445: 119-124.
    • (2008) Methods Mol Biol , vol.445 , pp. 119-124
    • Mizushima, N.1    Kuma, A.2
  • 53
    • 38049066964 scopus 로고    scopus 로고
    • Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice
    • Kuma A, Mizushima N. Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice. Autophagy 2008; 4: 61-62.
    • (2008) Autophagy , vol.4 , pp. 61-62
    • Kuma, A.1    Mizushima, N.2
  • 55
    • 0034757896 scopus 로고    scopus 로고
    • A novel assay to study autophagy: Regulation of autophagosome vacuole size by amino acid deprivation
    • Munafo DB, Colombo MI. A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. J Cell Sci 2001; 114: 3619-3629.
    • (2001) J Cell Sci , vol.114 , pp. 3619-3629
    • Munafo, D.B.1    Colombo, M.I.2
  • 56
    • 59249088570 scopus 로고    scopus 로고
    • Assays to assess autophagy induction and fusion of autophagic vacuoles with a degradative compartment, using monodansylcadaverine (MDC) and DQ-BSA
    • Vazquez CL, Colombo MI. Assays to assess autophagy induction and fusion of autophagic vacuoles with a degradative compartment, using monodansylcadaverine (MDC) and DQ-BSA. Methods Enzymol 2009; 452: 85-95.
    • (2009) Methods Enzymol , vol.452 , pp. 85-95
    • Vazquez, C.L.1    Colombo, M.I.2
  • 57
    • 56449107131 scopus 로고    scopus 로고
    • Association of autophagy defects with a malignant phenotype and poor prognosis of hepatocellular carcinoma
    • Ding ZB, Shi YH, Zhou J, Qiu SJ, Xu Y, Dai Z, et al . Association of autophagy defects with a malignant phenotype and poor prognosis of hepatocellular carcinoma. Cancer Res 2008; 68: 9167-9175.
    • (2008) Cancer Res , vol.68 , pp. 9167-9175
    • Ding, Z.B.1    Shi, Y.H.2    Zhou, J.3    Qiu, S.J.4    Xu, Y.5    Dai, Z.6
  • 58
    • 65249180744 scopus 로고    scopus 로고
    • The expression of beclin1 is associated with favorable prognosis in stage IIIB colon cancers
    • Li B, Li CY, Peng RQ, Wu XJ, Wang HY, Wan DS, et al. The expression of beclin1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy 2009; 5: 303-306.
    • (2009) Autophagy , vol.5 , pp. 303-306
    • Li, B.1    Li, C.Y.2    Peng, R.Q.3    Wu, X.J.4    Wang, H.Y.5    Wan, D.S.6
  • 59
    • 77649335850 scopus 로고    scopus 로고
    • Beclin1 and LC3 autophagic gene expression in cutaneous melanocytic lesions
    • ePub ahead of print; DOI: 10.1016/j.humpath.2009.09.004
    • Miracco C, Cevenini G, Franchi A, Luzi P, Cosci E, Mourmouras V, et al . Beclin1 and LC3 autophagic gene expression in cutaneous melanocytic lesions. Hum Pathol 2009; ePub ahead of print; DOI: 10.1016/j.humpath.2009.09.004.
    • (2009) Hum Pathol
    • Miracco, C.1    Cevenini, G.2    Franchi, A.3    Luzi, P.4    Cosci, E.5    Mourmouras, V.6
  • 61
    • 49649121765 scopus 로고    scopus 로고
    • E2F1 regulates autophagy and the transcription of autophagy genes
    • Polager S, Ofir M, Ginsberg D. E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 2008; 27: 4860-4864.
    • (2008) Oncogene , vol.27 , pp. 4860-4864
    • Polager, S.1    Ofir, M.2    Ginsberg, D.3
  • 64
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • Lum JJ, Bauer DE, Kong M, Harris MH, Li CY, Lindsten T, et al . Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005; 120: 237-249.
    • (2005) Cell , vol.120 , pp. 237-249
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.Y.5    Lindsten, T.6


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