pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 20, 1998, Pages 11661-11666

  Iliopoulos, Othon ^a   Ohh, Michael ^a   Kaelin Jr , William G ^a,b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL CELL GROWTH FACTOR; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; LIGASE; LYMPHOKINE; PRIMER DNA; PROTEIN; RECOMBINANT PROTEIN; SLC2A1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; VASCULOTROPIN; VASCULOTROPIN A; VHL PROTEIN, HUMAN; VON HIPPEL LINDAU PROTEIN; GENE PRODUCT;

ARTICLE; CELL LINE; CELL NUCLEUS; CHEMISTRY; CYTOSOL; GENETIC TRANSFECTION; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR WEIGHT; MUTATION; NUCLEOTIDE SEQUENCE; RNA TRANSLATION; TUMOR SUPPRESSOR GENE; VON HIPPEL LINDAU DISEASE; ALLELE; CARCINOMA CELL; CELL FRACTIONATION; CELL MEMBRANE; GENETIC ANALYSIS; HUMAN CELL; KIDNEY CARCINOMA; OPEN READING FRAME; PRIORITY JOURNAL; TRANSLATION INITIATION;

BASE SEQUENCE; CELL LINE; CELL NUCLEUS; CYTOSOL; DNA PRIMERS; ENDOTHELIAL GROWTH FACTORS; GENES, TUMOR SUPPRESSOR; GLUCOSE TRANSPORTER TYPE 1; HIPPEL-LINDAU DISEASE; HUMANS; KINETICS; LIGASES; LYMPHOKINES; MOLECULAR WEIGHT; MONOSACCHARIDE TRANSPORT PROTEINS; MUTATION; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PROTEINS; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 0032578357     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.20.11661     Document Type: Article

References (47)

1. McKusick, V. A. (1992) Mendelian Inheritance in Man (Johns Hopkins Univ. Press, Baltimore).
2. Maher, E. & Kaelin, W. G. (1997) Medicine 76, 381-91.
3. Latif, F., Tory, K., Gnarra, J., Yao, M., Duh, F.-M., Orcutt, M. L., Stackhouse, T., Kuzmin, I., Modi, W., Geil, L., et al. (1993) Science 260, 1317-1320.
4. Shuin, T., Kondo, K., Torigoe, S., Kishida, T., Kubota, Y., Hosaka, M., Nagashima, Y., Kitamura, H., Latif, F., Zbar, B., Lerman, M. I. & Yao, M. (1994) Cancer Res. 54, 2852-2855.
5. Lubensky, I. A., Gnarra, J. R., Bertheau, P., Walther, M. M., Linehan, W. M. & Zhuang, Z. (1996) Am. J. Pathol. 149, 2089-2094.
6. Tory, K., Brauch, H., Linehan, M., Barba, D., Oldfield, E., Filling-Katz, M., Seizinger, B., Nakamura, Y., White, R. & Marshall, F. (1989) J. Natl. Cancer Inst. 19, 1097-1101.
7. Gnarra, J. R., Tory, K., Weng, Y., Schmidt, L., Wei, M. H., Li, H., Latif, F., Liu, S., Chen, F., Duh, F.-M., et al. (1994) Nat. Genet. 7, 85-90.
8. Kanno, H., Kondo, K., Ito, S., Yamamoto, I., Fujii, S., Torigoe, S., Sakai, N., Hosaka, M., Shuin, T. & Yao, M. (1994) Cancer Res. 54, 4845-4847.
9. Herman, J. G., Latif, F., Weng, Y., Lerman, M. I., Zbar, B., Liu, S., Samid, D., Duan, D.-S. R., Gnarra, J. R., Linhean, W. M. & Baylin, S. B. (1994) Proc. Natl. Acad. Sci. USA 91, 9700-9704.
10. Iliopoulos, O., Kibel, A., Gray, S. & Kaelin, W. G. (1995) Nat. Med. 1, 822-826.
11. Gnarra, J. R., Zhou, S., Merrill, M. J., Wagner, J., Krumm, A., Papavassiliou, E., Oldfield, E. H., Klausner, R. D. & Linehan, W. M. (1996) Proc. Natl. Acad. Sd. USA 93, 10589-10594.
12. Corless, C. L., Kibel, A., Iliopoulos, O. & Kaelin, W. G. J. (1997) Hum. Pathol. 28, 459-464.
13. Los, M., Jansen, G. H., Kaelin, W. G., Lips, C. J. M., Blijham, G. H. & Voest, E. E. (1996) Lab. Invest. 75, 231-238.
14. Pause, A., Lee, S., Worrell, R. A., Chen, D. Y. T., Burgess, W. H., Linehan, W. M. & Klausner, R. D. (1997) Proc. Natl. Acad. Sci. USA 94, 2156-2161.
15. Lee, S., Chen, D. Y. T., Humphrey, J. S., Gnarra, J. R., Linehan, W. M. & Klausner, R. D. (1996) Proc. Natl. Acad. Sci. USA 93, 1770-1775.
16. Aso, T., Lane, W. S., Conaway, J. W. & Conaway, R. C. (1995) Science 269, 1439-1443.
17. Duan, D. R., Pause, A., Burgress, W., Aso, T., Chen, D. Y. T., Garrett, K. P., Conaway, R. C., Conaway, J. W., Linehan, W. M. & Klausner, R. D. (1995) Science 269, 1402-1406.
18. Kibel, A., Iliopoulos, O., DeCaprio, J. D. & Kaelin, W. G. (1995) Science 269, 1444-1446.
19. Lonergan, K. M., Iliopoulos, O., Ohh, M., Kamura, T., Conaway, R. C., Conaway, J. W. & Kaelin, W. G. (1998) Mol. Cell. Biol. 18, 732-741.
20. Gao, J., Naglich, J. G., Laidlaw, J., Whaley, J. M., Seizinger, B. R. & Kley, N. (1995) Cancer Res. 55, 743-747.
21. Bai, C., Sen, P., Hofmann, K., Ma, L., Goebl, M., Harper, J. W. & Elledge, S. J. (1996) Cell 86, 263-274.
22. Mathias, N., Johnson, S., Winey, M., Adams, A., Goetsch, L., Pringle, J., Byers, B. & Goebl, M. (1996) Mol. Cell. Biol. 16, 6634-6643.
23. Wizigmann-Voos, S., Breier, G., Risau, W. & Plate, K. (1995) Cancer Res. 55, 1358-1364.
24. Iliopoulos, O. & Kaelin, W. G. (1997) Mol. Med. 3, 289-293.
25. Siemeister, G., Weindel, K., Mohrs, K., Barleon, B., Martiny-Baron, G. & Marme, D. (1996) Cancer Res. 56, 2299-2301.
26. Iliopoulos, O., Jiang, C., Levy, A. P., Kaelin, W. G. & Goldberg, M. A. (1996) Proc. Natl. Acad. Sci. USA 93, 10595-10599.
27. Mukhopadhyay, D., Knebelmann, B., Cohen, H., Ananth, S. & Sukhatme, V. (1997) Mol. Cell. Biol. 17, 5629-39.
28. Kuebelmann, B., Ananth, S., Cohen, H. T. & Sukhatme, V. P. (1998) Cancer Res. 58, 226-231.
29. Plate, K., Breier, G., Weich, H. & Risau, W. (1992) Nature (London) 359, 845-848.
30. Ohh, M., Yauch, R. L., Lonergan, K. M., Whaley, J. M., Stemmer-Rachamimov, A. O., Louis, D. N., Gavin, B. J., Kley, N., Kaelin, W. G. & Iliopoulos, O. (1998) Mol. Cell 1, 959-968.
31. Giancotti, F. G. & Ruoslahti, E. (1990) Cell 60, 849-859.
32. Pasqualini, R., Bourdoulous, S., Koivunen, E., Woods, V., Jr. & Ruoslahti, E. (1996) Nat. Med 2, 1197-1203.
33. Brooks, P. C., Clark, R. A. & Cheresh, D. A. (1994) Science 264 569-571.
34. Maniatis, T., Fritsch, E. F. & Sambrook, J. (1982) Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY).
35. Krek, W., Livingston, D. M. & Shirodkar, S. (1993) Science 262, 1557-1560.
36. Harlow, E., Crawford, L. V., Pim, D. C. & Williamson, N. M. (1981) J. Virol. 39, 861-869.
37. Harlow, E. & Lane, D. (1988) Antibodies: A Laboratory Manual (Cold Spring Harbor Lab. Press, Plainview, NY).
38. Lee, W.-H., Shew, J.-Y., Hong, F. D., Sery, T. W., Donoso, L. A., Young, L.-J., Bookstein, R. & Lee, E. Y.-H. P. (1987) Nature (London) 329, 642-645.
39. Kozak, M. (1989) J. Cell Biol. 108, 229-241.
40. Kozak, M. (1987) J. Mol. Biol. 196, 947-950.
41. Iizula, N., Chen, C., Yang, Q., Johannes, G. & Sarnow, P. (1995) Curr. Top. Microbiol. Immunol. 203, 155-177.
42. Ackland, P., Dixon, M., Peters, G. & Dickson, C. (1990) Nature (London) 343, 662-665.
43. Gillman, E. C., Slusher, L. B., Martin, N. C. & Hopper, A. K. (1991) Mol. Cell. Biol. 11, 2382-2390.
44. Vagner, S., Gensac, M.-C., Maret, A., Bayard, F., Amalric, F., Prats, H. & Prats, A.-C. (1995) Mol. Cell. Biol. 15, 35-44.
45. Delmas, V., Laoide, B. M., Masquilier, D., De Groot, R., Foulkes, N. S. & Sassone-Corsi, P. (1992) Proc. Natl. Acad. Sci. USA 89, 4226-4230.
46. Kishida, T., Stackhouse, T. M., Chen, F., Lerman, M. I. & Zbar, B. (1995) Cancer Res. 55, 4544-4548.
47. Duan, D. R., Humphrey, J. S., Chen, D. Y. T., Weng, Y., Sukegawa, J., Lee, S., Gnarra, J. R., Linehan, W. M. & Klausner, R. D. (1995) Proc. Natl. Acad. Sci. USA 92, 6495-6499.