-
1
-
-
84889737859
-
-
[website on the internet]. Available from
-
American Society of Cell and Gene Therapy. [website on the internet]. Available from: http: //www.asgct.org/about_gene_therapy/ defined.php
-
American Society of Cell and Gene Therapy
-
-
-
2
-
-
79751506542
-
Gene therapy finds its niche
-
Sheridan C. Gene therapy finds its niche. Nat Biotechnol 2011; 29(2): 121-8.
-
(2011)
Nat Biotechnol
, vol.29
, Issue.2
, pp. 121-128
-
-
Sheridan, C.1
-
3
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan JR, Rommens JM, Kerem B, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 1989; 245(4922): 1066-73.
-
(1989)
Science
, vol.245
, Issue.4922
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
-
4
-
-
78649647597
-
Role of epithelial HCO3 transport in mucin secretion: Lessons from cystic fibrosis
-
Quinton PM. Role of epithelial HCO3 transport in mucin secretion: lessons from cystic fibrosis. Am J Physiol Cell Physiol 2010; 299(6): C1222-C1233.
-
(2010)
Am J Physiol Cell Physiol
, vol.299
, Issue.6
-
-
Quinton, P.M.1
-
5
-
-
0001752544
-
Cystic fibrosis
-
Scriver AB SWVD, editor, New York: McGraw-Hill
-
Welsh M, Ramsey BW, Accurso F, Cutting GR. Cystic Fibrosis. In: Scriver AB SWVD, editor. The Molecular and Metabolic Basis of Inherited Disease. New York: McGraw-Hill; 2001. p. 5121-88.
-
(2001)
The Molecular and Metabolic Basis of Inherited Disease
, pp. 5121-5188
-
-
Welsh, M.1
Ramsey, B.W.2
Accurso, F.3
Cutting, G.R.4
-
6
-
-
47049095809
-
Cystic Fibrosis: The Mechanisms of Pathogenesis of an Inherited Lung Disorder
-
Clunes MT, Boucher RC. Cystic Fibrosis: The Mechanisms of Pathogenesis of an Inherited Lung Disorder. Drug Discov Today Dis Mech 2007; 4(2): 63-72.
-
(2007)
Drug Discov Today Dis Mech
, vol.4
, Issue.2
, pp. 63-72
-
-
Clunes, M.T.1
Boucher, R.C.2
-
7
-
-
79953215718
-
Current status and future directions of gene and cell therapy for cystic fibrosis
-
Griesenbach U, Alton EW. Current status and future directions of gene and cell therapy for cystic fibrosis. BioDrugs 2011; 25(2): 77-88.
-
(2011)
BioDrugs
, vol.25
, Issue.2
, pp. 77-88
-
-
Griesenbach, U.1
Alton, E.W.2
-
8
-
-
0026951303
-
Submucosal glands are the predominant site of CFTR expression in the human bronchus
-
Engelhardt JF, Yankaskas JR, Ernst SA, et al. Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nat Genet 1992; 2(3): 240-8.
-
(1992)
Nat Genet
, vol.2
, Issue.3
, pp. 240-248
-
-
Engelhardt, J.F.1
Yankaskas, J.R.2
Ernst, S.A.3
-
9
-
-
18244377969
-
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia
-
Kreda SM, Mall M, Mengos A, et al. Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia. Mol Biol Cell 2005; 16(5): 2154-67.
-
(2005)
Mol Biol Cell
, vol.16
, Issue.5
, pp. 2154-2167
-
-
Kreda, S.M.1
Mall, M.2
Mengos, A.3
-
10
-
-
0033918281
-
Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells
-
Penque D, Mendes F, Beck S, et al. Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells. Lab Invest 2000; 80(6): 857-68.
-
(2000)
Lab Invest
, vol.80
, Issue.6
, pp. 857-868
-
-
Penque, D.1
Mendes, F.2
Beck, S.3
-
11
-
-
72149093771
-
Disease-causing mutations in the cystic fibrosis transmembrane conductance regulator determine the functional responses of alveolar macrophages
-
Deriy LV, Gomez EA, Zhang G, et al. Disease-causing mutations in the cystic fibrosis transmembrane conductance regulator determine the functional responses of alveolar macrophages. J Biol Chem 2009; 284(51): 35926-38.
-
(2009)
J Biol Chem
, vol.284
, Issue.51
, pp. 35926-35938
-
-
Deriy, L.V.1
Gomez, E.A.2
Zhang, G.3
-
12
-
-
33748654201
-
CFTR Expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis
-
Painter RG, Valentine VG, Lanson NA, Jr., et al. CFTR Expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis. Biochemistry 2006; 45(34): 10260-9.
-
(2006)
Biochemistry
, vol.45
, Issue.34
, pp. 10260-10269
-
-
Painter, R.G.1
Valentine, V.G.2
Lanson Jr., N.A.3
-
13
-
-
67049172475
-
Defective organellar acidification as a cause of cystic fibrosis lung disease: Reexamination of a recurring hypothesis
-
Haggie PM, Verkman AS. Defective organellar acidification as a cause of cystic fibrosis lung disease: reexamination of a recurring hypothesis. Am J Physiol Lung Cell Mol Physiol 2009; 296(6): L859-L867.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.296
, Issue.6
-
-
Haggie, P.M.1
Verkman, A.S.2
-
14
-
-
0027502580
-
Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA
-
Chu CS, Trapnell BC, Curristin S, Cutting GR, Crystal RG. Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA. Nat Genet 1993; 3(2): 151-6.
-
(1993)
Nat Genet
, vol.3
, Issue.2
, pp. 151-156
-
-
Chu, C.S.1
Trapnell, B.C.2
Curristin, S.3
Cutting, G.R.4
Crystal, R.G.5
-
15
-
-
0026918861
-
Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis
-
Johnson LG, Olsen JC, Sarkadi B, Moore KL, Swanstrom R, Boucher RC. Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis. Nat Genet 1992; 2(1): 21-5.
-
(1992)
Nat Genet
, vol.2
, Issue.1
, pp. 21-25
-
-
Johnson, L.G.1
Olsen, J.C.2
Sarkadi, B.3
Moore, K.L.4
Swanstrom, R.5
Boucher, R.C.6
-
16
-
-
27944491619
-
Gene transfer of CFTR to airway epithelia: Low levels of expression are sufficient to correct Cltransport and overexpression can generate basolateral CFTR
-
Farmen SL, Karp PH, Ng P, et al. Gene transfer of CFTR to airway epithelia: low levels of expression are sufficient to correct Cltransport and overexpression can generate basolateral CFTR. Am J Physiol Lung Cell Mol Physiol 2005; 289(6): L1123-L1130.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
, Issue.6
-
-
Farmen, S.L.1
Karp, P.H.2
Ng, P.3
-
17
-
-
68049143467
-
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium
-
Zhang L, Button B, Gabriel SE, et al. CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium. PLoS Biol 2009; 7(7): e1000155.
-
(2009)
PLoS Biol
, vol.7
, Issue.7
-
-
Zhang, L.1
Button, B.2
Gabriel, S.E.3
-
18
-
-
0028912888
-
Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells
-
Johnson LG, Boyles SE, Wilson J, Boucher RC. Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells. J Clin Invest 1995; 95(3): 1377-82.
-
(1995)
J Clin Invest
, vol.95
, Issue.3
, pp. 1377-1382
-
-
Johnson, L.G.1
Boyles, S.E.2
Wilson, J.3
Boucher, R.C.4
-
19
-
-
78649915334
-
Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia
-
Chen JH, Stoltz DA, Karp PH, et al. Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia. Cell 2010; 143(6): 911-23.
-
(2010)
Cell
, vol.143
, Issue.6
, pp. 911-923
-
-
Chen, J.H.1
Stoltz, D.A.2
Karp, P.H.3
-
20
-
-
60149103022
-
Extracellular barriers in respiratory gene therapy
-
Sanders N, Rudolph C, Braeckmans K, De Smedt SC, Demeester J. Extracellular barriers in respiratory gene therapy. Adv Drug Deliv Rev 2009; 61(2): 115-27.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.2
, pp. 115-127
-
-
Sanders, N.1
Rudolph, C.2
Braeckmans, K.3
de Smedt, S.C.4
Demeester, J.5
-
21
-
-
0042025196
-
Poly (D, L-lactide-coglycolide)/ DNA microspheres to facilitate prolonged transgene expression in airway epithelium in vitro, ex vivo and in vivo
-
Stern M, Ulrich K, Geddes DM, Alton EW. Poly (D, L-lactide-coglycolide)/ DNA microspheres to facilitate prolonged transgene expression in airway epithelium in vitro, ex vivo and in vivo. Gene Ther 2003; 10(16): 1282-8.
-
(2003)
Gene Ther
, vol.10
, Issue.16
, pp. 1282-1288
-
-
Stern, M.1
Ulrich, K.2
Geddes, D.M.3
Alton, E.W.4
-
22
-
-
0034425984
-
Efficient gene transfer to airway epithelium using recombinant Sendai virus
-
Yonemitsu Y, Kitson C, Ferrari S, et al. Efficient gene transfer to airway epithelium using recombinant Sendai virus. Nat Biotechnol 2000; 18(9): 970-3.
-
(2000)
Nat Biotechnol
, vol.18
, Issue.9
, pp. 970-973
-
-
Yonemitsu, Y.1
Kitson, C.2
Ferrari, S.3
-
23
-
-
18244409874
-
Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors
-
Sinn PL, Shah AJ, Donovan MD, McCray PB, Jr. Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors. Am J Respir Cell Mol Biol 2005; 32(5): 404-10.
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, Issue.5
, pp. 404-410
-
-
Sinn, P.L.1
Shah, A.J.2
Donovan, M.D.3
McCray Jr., P.B.4
-
24
-
-
74449092542
-
The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways
-
Griesenbach U, Meng C, Farley R, et al. The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways. Biomaterials 2010; 31(9): 2665-72.
-
(2010)
Biomaterials
, vol.31
, Issue.9
, pp. 2665-2672
-
-
Griesenbach, U.1
Meng, C.2
Farley, R.3
-
25
-
-
0032853699
-
Immune responses to adenovirus and adeno-associated virus in humans
-
Chirmule N, Propert K, Magosin S, Qian Y, Qian R, Wilson J. Immune responses to adenovirus and adeno-associated virus in humans. Gene Ther 1999; 6(9): 1574-83.
-
(1999)
Gene Ther
, vol.6
, Issue.9
, pp. 1574-1583
-
-
Chirmule, N.1
Propert, K.2
Magosin, S.3
Qian, Y.4
Qian, R.5
Wilson, J.6
-
26
-
-
84889758577
-
Repeat Aerosol Delivery of Concentrated PEI/pDNA to the Sheep Lung
-
Ref Type: Abstract
-
McLachlan G, Davies LA, Gordon C, et al. Repeat Aerosol Delivery of Concentrated PEI/pDNA to the Sheep Lung. Mol.Ther. 18[S1]. 2010. Ref Type: Abstract
-
(2010)
Mol.Ther
, vol.18
, Issue.S1
-
-
McLachlan, G.1
Davies, L.A.2
Gordon, C.3
-
27
-
-
0033924663
-
Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis
-
Hyde SC, Southern KW, Gileadi U, et al. Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis. Gene Ther 2000; 7(13): 1156-65.
-
(2000)
Gene Ther
, vol.7
, Issue.13
, pp. 1156-1165
-
-
Hyde, S.C.1
Southern, K.W.2
Gileadi, U.3
-
28
-
-
0031777961
-
Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer
-
Pickles RJ, McCarty D, Matsui H, Hart PJ, Randell SH, Boucher RC. Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer. J Virol 1998; 72(7): 6014-23.
-
(1998)
J Virol
, vol.72
, Issue.7
, pp. 6014-6023
-
-
Pickles, R.J.1
McCarty, D.2
Matsui, H.3
Hart, P.J.4
Randell, S.H.5
Boucher, R.C.6
-
29
-
-
8844258028
-
A defective nontransmissible recombinant Sendai virus mediates efficient gene transfer to airway epithelium in vivo
-
Ferrari S, Griesenbach U, Shiraki-Iida T, et al. A defective nontransmissible recombinant Sendai virus mediates efficient gene transfer to airway epithelium in vivo. Gene Ther 2004; 11(22): 1659-64.
-
(2004)
Gene Ther
, vol.11
, Issue.22
, pp. 1659-1664
-
-
Ferrari, S.1
Griesenbach, U.2
Shiraki-Iida, T.3
-
30
-
-
65549146847
-
Learning from the viral journey: How to enter cells and how to overcome intracellular barriers to reach the nucleus
-
Mudhakir D, Harashima H. Learning from the viral journey: how to enter cells and how to overcome intracellular barriers to reach the nucleus. AAPS J 2009; 11(1): 65-77.
-
(2009)
AAPS J
, vol.11
, Issue.1
, pp. 65-77
-
-
Mudhakir, D.1
Harashima, H.2
-
31
-
-
77950857472
-
Progress and prospects: Nuclear import of nonviral vectors
-
Lam AP, Dean DA. Progress and prospects: nuclear import of nonviral vectors. Gene Ther 2010; 17(4): 439-47.
-
(2010)
Gene Ther
, vol.17
, Issue.4
, pp. 439-447
-
-
Lam, A.P.1
Dean, D.A.2
-
32
-
-
20744433079
-
Intracellular trafficking of adeno-associated viral vectors
-
Ding W, Zhang L, Yan Z, Engelhardt JF. Intracellular trafficking of adeno-associated viral vectors. Gene Ther 2005; 12(11): 873-80.
-
(2005)
Gene Ther
, vol.12
, Issue.11
, pp. 873-880
-
-
Ding, W.1
Zhang, L.2
Yan, Z.3
Engelhardt, J.F.4
-
33
-
-
77749342887
-
Flexible use of nuclear import pathways by HIV-1
-
Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, et al. Flexible use of nuclear import pathways by HIV-1. Cell Host Microbe 2010; 7(3): 221-33.
-
(2010)
Cell Host Microbe
, vol.7
, Issue.3
, pp. 221-233
-
-
Lee, K.1
Ambrose, Z.2
Martin, T.D.3
Oztop, I.4
Mulky, A.5
Julias, J.G.6
-
34
-
-
0025094612
-
Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer
-
Drumm ML, Pope HA, Cliff WH, et al. Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer. Cell 1990; 62(6): 1227-33.
-
(1990)
Cell
, vol.62
, Issue.6
, pp. 1227-1233
-
-
Drumm, M.L.1
Pope, H.A.2
Cliff, W.H.3
-
35
-
-
0026558496
-
In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium
-
Rosenfeld MA, Yoshimura K, Trapnell BC, et al. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell 1992; 68(1): 143-55.
-
(1992)
Cell
, vol.68
, Issue.1
, pp. 143-155
-
-
Rosenfeld, M.A.1
Yoshimura, K.2
Trapnell, B.C.3
-
36
-
-
0027475701
-
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
-
Hyde SC, Gill DR, Higgins CF, et al. Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature 1993; 362(6417): 250-5.
-
(1993)
Nature
, vol.362
, Issue.6417
, pp. 250-255
-
-
Hyde, S.C.1
Gill, D.R.2
Higgins, C.F.3
-
37
-
-
0027377523
-
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis
-
Zabner J, Couture LA, Gregory RJ, Graham SM, Smith AE, Welsh MJ. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell 1993; 75(2): 207-16.
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 207-216
-
-
Zabner, J.1
Couture, L.A.2
Gregory, R.J.3
Graham, S.M.4
Smith, A.E.5
Welsh, M.J.6
-
38
-
-
0028168641
-
Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
-
Crystal RG, McElvaney NG, Rosenfeld MA, et al. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet 1994; 8(1): 42-51.
-
(1994)
Nat Genet
, vol.8
, Issue.1
, pp. 42-51
-
-
Crystal, R.G.1
McElvaney, N.G.2
Rosenfeld, M.A.3
-
39
-
-
0028913411
-
Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Caplen NJ, Alton EW, Middleton PG, et al. Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nat Med 1995; 1(1): 39-46.
-
(1995)
Nat Med
, vol.1
, Issue.1
, pp. 39-46
-
-
Caplen, N.J.1
Alton, E.W.2
Middleton, P.G.3
-
40
-
-
0033586375
-
Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: A double-blind placebo-controlled trial
-
Alton EW, Stern M, Farley R, et al. Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial. Lancet 1999; 353(9157): 947-54.
-
(1999)
Lancet
, vol.353
, Issue.9157
, pp. 947-954
-
-
Alton, E.W.1
Stern, M.2
Farley, R.3
-
41
-
-
43049178300
-
Progress and prospects: Gene therapy for genetic diseases with helper-dependent adenoviral vectors
-
Brunetti-Pierri N, Ng P. Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors. Gene Ther 2008; 15(8): 553-60.
-
(2008)
Gene Ther
, vol.15
, Issue.8
, pp. 553-560
-
-
Brunetti-Pierri, N.1
Ng, P.2
-
43
-
-
60149095412
-
Gene transfer to the lung: Lessons learned from more than 2 decades of CF gene therapy
-
Griesenbach U, Alton EW. Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy. Adv Drug Deliv Rev 2009; 61(2): 128-39.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, Issue.2
, pp. 128-139
-
-
Griesenbach, U.1
Alton, E.W.2
-
44
-
-
0033537837
-
Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia
-
Walters RW, Grunst T, Bergelson JM, Finberg RW, Welsh MJ, Zabner J. Basolateral localization of fiber receptors limits adenovirus infection from the apical surface of airway epithelia. J Biol Chem 1999; 274(15): 10219-26.
-
(1999)
J Biol Chem
, vol.274
, Issue.15
, pp. 10219-11026
-
-
Walters, R.W.1
Grunst, T.2
Bergelson, J.M.3
Finberg, R.W.4
Welsh, M.J.5
Zabner, J.6
-
45
-
-
0347815187
-
Transient increase in lung epithelial tight junction permeability: An additional mechanism for enhancement of lung transgene expression by perfluorochemical liquids
-
Weiss DJ, Beckett T, Bonneau L, Young J, Kolls JK, Wang G. Transient increase in lung epithelial tight junction permeability: an additional mechanism for enhancement of lung transgene expression by perfluorochemical liquids. Mol Ther 2003; 8(6): 927-35.
-
(2003)
Mol Ther
, vol.8
, Issue.6
, pp. 927-935
-
-
Weiss, D.J.1
Beckett, T.2
Bonneau, L.3
Young, J.4
Kolls, J.K.5
Wang, G.6
-
46
-
-
27944457244
-
Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter
-
Koehler DR, Frndova H, Leung K, et al. Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter. J Gene Med 2005; 7(11): 1409-20.
-
(2005)
J Gene Med
, vol.7
, Issue.11
, pp. 1409-1420
-
-
Koehler, D.R.1
Frndova, H.2
Leung, K.3
-
47
-
-
35848970333
-
Pulmonary delivery of adenovirus vector formulated with dexamethasonespermine facilitates homologous vector re-administration
-
Price AR, Limberis MP, Wilson JM, Diamond SL. Pulmonary delivery of adenovirus vector formulated with dexamethasonespermine facilitates homologous vector re-administration. Gene Ther 2007; 14(22): 1594-604.
-
(2007)
Gene Ther
, vol.14
, Issue.22
, pp. 1594-1604
-
-
Price, A.R.1
Limberis, M.P.2
Wilson, J.M.3
Diamond, S.L.4
-
48
-
-
0034056840
-
Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40- CD40 ligand interactions
-
Chirmule N, Raper SE, Burkly L, et al. Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40- CD40 ligand interactions. J Virol 2000; 74(7): 3345-52.
-
(2000)
J Virol
, vol.74
, Issue.7
, pp. 3345-3352
-
-
Chirmule, N.1
Raper, S.E.2
Burkly, L.3
-
49
-
-
0035447558
-
Budesonide enhances repeated gene transfer and expression in the lung with adenoviral vectors
-
Kolb M, Inman M, Margetts PJ, Galt T, Gauldie J. Budesonide enhances repeated gene transfer and expression in the lung with adenoviral vectors. Am J Respir Crit Care Med 2001; 164(5): 866-72.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, Issue.5
, pp. 866-872
-
-
Kolb, M.1
Inman, M.2
Margetts, P.J.3
Galt, T.4
Gauldie, J.5
-
50
-
-
33846271820
-
Viral vector-mediated and cellbased therapies for treatment of cystic fibrosis
-
Flotte TR, Ng P, Dylla DE, et al. Viral vector-mediated and cellbased therapies for treatment of cystic fibrosis. Mol Ther 2007; 15(2): 229-41.
-
(2007)
Mol Ther
, vol.15
, Issue.2
, pp. 229-241
-
-
Flotte, T.R.1
Ng, P.2
Dylla, D.E.3
-
51
-
-
79951517549
-
Readministration of helper-dependent adenoviral vectors to mouse airway mediated via transient immunosuppression
-
Cao H, Yang T, Li XF, et al. Readministration of helper-dependent adenoviral vectors to mouse airway mediated via transient immunosuppression. Gene Ther 2011; 18(2): 173-81.
-
(2011)
Gene Ther
, vol.18
, Issue.2
, pp. 173-181
-
-
Cao, H.1
Yang, T.2
Li, X.F.3
-
52
-
-
79951517862
-
Validation of recombinant Sendai virus in a non-natural host model
-
Griesenbach U, McLachlan G, Owaki T, et al. Validation of recombinant Sendai virus in a non-natural host model. Gene Ther 2010; 18(2): 182-8.
-
(2010)
Gene Ther
, vol.18
, Issue.2
, pp. 182-188
-
-
Griesenbach, U.1
McLachlan, G.2
Owaki, T.3
-
53
-
-
33645139296
-
Effect of tolerance induction to immunodominant T-cell epitopes of Sendai virus on gene expression following repeat administration to lung
-
Griesenbach U, Boyton RJ, Somerton L, et al. Effect of tolerance induction to immunodominant T-cell epitopes of Sendai virus on gene expression following repeat administration to lung. Gene Ther 2006; 13(5): 449-56.
-
(2006)
Gene Ther
, vol.13
, Issue.5
, pp. 449-456
-
-
Griesenbach, U.1
Boyton, R.J.2
Somerton, L.3
-
54
-
-
0347364650
-
Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia
-
Koehler DR, Sajjan U, Chow YH, et al. Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia. Proc Natl Acad Sci USA 2003; 100(26): 15364-9.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.26
, pp. 15364-15369
-
-
Koehler, D.R.1
Sajjan, U.2
Chow, Y.H.3
-
55
-
-
1342339826
-
Delivery of CFTR by adenoviral vector to cys tic fibrosis mouse lung in a model of chronic Pseudomonas aeruginosa lung infection
-
van Heeckeren AM, Scaria A, Schluchter MD, Ferkol TW, Wadsworth S, Davis PB. Delivery of CFTR by adenoviral vector to cys tic fibrosis mouse lung in a model of chronic Pseudomonas aeruginosa lung infection. Am J Physiol Lung Cell Mol Physiol 2004; 286(4): L717-L726.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.286
, Issue.4
-
-
van Heeckeren, A.M.1
Scaria, A.2
Schluchter, M.D.3
Ferkol, T.W.4
Wadsworth, S.5
Davis, P.B.6
-
56
-
-
0031040502
-
Reversal of cystic fibrosis phenotype in mice by gene therapy in utero
-
Larson JE, Morrow SL, Happel L, Sharp JF, Cohen JC. Reversal of cystic fibrosis phenotype in mice by gene therapy in utero. Lancet 1997; 349(9052): 619-20.
-
(1997)
Lancet
, vol.349
, Issue.9052
, pp. 619-620
-
-
Larson, J.E.1
Morrow, S.L.2
Happel, L.3
Sharp, J.F.4
Cohen, J.C.5
-
57
-
-
42549089142
-
Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice
-
Buckley SM, Waddington SN, Jezzard S, et al. Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice. Mol Ther 2008; 16(5): 819-24.
-
(2008)
Mol Ther
, vol.16
, Issue.5
, pp. 819-824
-
-
Buckley, S.M.1
Waddington, S.N.2
Jezzard, S.3
-
58
-
-
42549129355
-
Adenovirusmediated in utero expression of CFTR does not improve survival of CFTR knockout mice
-
Davies LA, Varathalingam A, Painter H, et al. Adenovirusmediated in utero expression of CFTR does not improve survival of CFTR knockout mice. Mol Ther 2008; 16(5): 812-8.
-
(2008)
Mol Ther
, vol.16
, Issue.5
, pp. 812-818
-
-
Davies, L.A.1
Varathalingam, A.2
Painter, H.3
-
59
-
-
77749237132
-
Pathology of gastrointestinal organs in a porcine model of cystic fibrosis
-
Meyerholz DK, Stoltz DA, Pezzulo AA, Welsh MJ. Pathology of gastrointestinal organs in a porcine model of cystic fibrosis. Am J Pathol 2010; 176(3): 1377-89.
-
(2010)
Am J Pathol
, vol.176
, Issue.3
, pp. 1377-1389
-
-
Meyerholz, D.K.1
Stoltz, D.A.2
Pezzulo, A.A.3
Welsh, M.J.4
-
60
-
-
0031691257
-
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
-
Duan D, Sharma P, Yang J, et al. Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J Virol 1998; 72(11): 8568-77.
-
(1998)
J Virol
, vol.72
, Issue.11
, pp. 8568-8577
-
-
Duan, D.1
Sharma, P.2
Yang, J.3
-
61
-
-
21244463942
-
Recent developments in recombinant AAV-mediated gene therapy for lung diseases
-
Flotte TR. Recent developments in recombinant AAV-mediated gene therapy for lung diseases. Curr Gene Ther 2005; 5(3): 361-6.
-
(2005)
Curr Gene Ther
, vol.5
, Issue.3
, pp. 361-366
-
-
Flotte, T.R.1
-
62
-
-
10944269753
-
Integration of adenoassociated virus (AAV) and recombinant AAV vectors
-
McCarty DM, Young SM, Jr., Samulski RJ. Integration of adenoassociated virus (AAV) and recombinant AAV vectors. Annu Rev Genet 2004; 38: 819-45.
-
(2004)
Annu Rev Genet
, vol.38
, pp. 819-845
-
-
McCarty, D.M.1
Young Jr., S.M.2
Samulski, R.J.3
-
63
-
-
10744227749
-
Repeated adenoassociated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: A multicenter, double-blind, placebo-controlled trial
-
Moss RB, Rodman D, Spencer LT, et al. Repeated adenoassociated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial. Chest 2004; 125(2): 509-21.
-
(2004)
Chest
, vol.125
, Issue.2
, pp. 509-521
-
-
Moss, R.B.1
Rodman, D.2
Spencer, L.T.3
-
64
-
-
34548512049
-
Repeated aerosolized AAVCFTR for treatment of cystic fibrosis: A randomized placebocontrolled phase 2B trial
-
Moss RB, Milla C, Colombo J, et al. Repeated aerosolized AAVCFTR for treatment of cystic fibrosis: a randomized placebocontrolled phase 2B trial. Hum Gene Ther 2007; 18(8): 726-32.
-
(2007)
Hum Gene Ther
, vol.18
, Issue.8
, pp. 726-732
-
-
Moss, R.B.1
Milla, C.2
Colombo, J.3
-
66
-
-
62549150024
-
Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro
-
Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM. Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro. Mol Ther 2009; 17(2): 294-301.
-
(2009)
Mol Ther
, vol.17
, Issue.2
, pp. 294-301
-
-
Limberis, M.P.1
Vandenberghe, L.H.2
Zhang, L.3
Pickles, R.J.4
Wilson, J.M.5
-
67
-
-
0036678455
-
The atomic structure of adenoassociated virus (AAV-2), a vector for human gene therapy
-
Xie Q, Bu W, Bhatia S, et al. The atomic structure of adenoassociated virus (AAV-2), a vector for human gene therapy. Proc Natl Acad Sci USA 2002; 99(16): 10405-10.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.16
, pp. 10405-10410
-
-
Xie, Q.1
Bu, W.2
Bhatia, S.3
-
68
-
-
57749190573
-
Genetic modification of adeno-associated viral vector type 2 capsid enhances gene transfer efficiency in polarized human airway epithelial cells
-
White AF, Mazur M, Sorscher EJ, Zinn KR, Ponnazhagan S. Genetic modification of adeno-associated viral vector type 2 capsid enhances gene transfer efficiency in polarized human airway epithelial cells. Hum Gene Ther 2008; 19(12): 1407-14.
-
(2008)
Hum Gene Ther
, vol.19
, Issue.12
, pp. 1407-1414
-
-
White, A.F.1
Mazur, M.2
Sorscher, E.J.3
Zinn, K.R.4
Ponnazhagan, S.5
-
69
-
-
32344438754
-
Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
-
Maheshri N, Koerber JT, Kaspar BK, Schaffer DV. Directed evolution of adeno-associated virus yields enhanced gene delivery vectors. Nat Biotechnol 2006; 24(2): 198-204.
-
(2006)
Nat Biotechnol
, vol.24
, Issue.2
, pp. 198-204
-
-
Maheshri, N.1
Koerber, J.T.2
Kaspar, B.K.3
Schaffer, D.V.4
-
70
-
-
62649174755
-
Directed evolution of adeno-associated virus to an infectious respiratory virus
-
Excoffon KJ, Koerber JT, Dickey DD, et al. Directed evolution of adeno-associated virus to an infectious respiratory virus. Proc Natl Acad Sci USA 2009; 106(10): 3865-70.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.10
, pp. 3865-3870
-
-
Excoffon, K.J.1
Koerber, J.T.2
Dickey, D.D.3
-
71
-
-
73849130017
-
Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium
-
Li W, Zhang L, Johnson JS, et al. Generation of novel AAV variants by directed evolution for improved CFTR delivery to human ciliated airway epithelium. Mol Ther 2009; 17(12): 2067-77.
-
(2009)
Mol Ther
, vol.17
, Issue.12
, pp. 2067-2077
-
-
Li, W.1
Zhang, L.2
Johnson, J.S.3
-
72
-
-
35348836681
-
Comparative biology of rAAV transduction in ferret, pig and human airway epithelia
-
Liu X, Luo M, Guo C, Yan Z, Wang Y, Engelhardt JF. Comparative biology of rAAV transduction in ferret, pig and human airway epithelia. Gene Ther 2007; 14(21): 1543-8.
-
(2007)
Gene Ther
, vol.14
, Issue.21
, pp. 1543-1548
-
-
Liu, X.1
Luo, M.2
Guo, C.3
Yan, Z.4
Wang, Y.5
Engelhardt, J.F.6
-
73
-
-
0037791759
-
Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia
-
Ding W, Yan Z, Zak R, Saavedra M, Rodman DM, Engelhardt JF. Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia. J Virol 2003; 77(13): 7361-6.
-
(2003)
J Virol
, vol.77
, Issue.13
, pp. 7361-7366
-
-
Ding, W.1
Yan, Z.2
Zak, R.3
Saavedra, M.4
Rodman, D.M.5
Engelhardt, J.F.6
-
74
-
-
33846192000
-
Hybrid adeno-associated virus bearing nonhomologous inverted terminal repeats enhances dual-vector reconstruction of minigenes in vivo
-
Yan Z, Lei-Butters DC, Zhang Y, Zak R, Engelhardt JF. Hybrid adeno-associated virus bearing nonhomologous inverted terminal repeats enhances dual-vector reconstruction of minigenes in vivo. Hum Gene Ther 2007; 18(1): 81-7.
-
(2007)
Hum Gene Ther
, vol.18
, Issue.1
, pp. 81-87
-
-
Yan, Z.1
Lei-Butters, D.C.2
Zhang, Y.3
Zak, R.4
Engelhardt, J.F.5
-
75
-
-
10344225049
-
Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway
-
Zhang LN, Karp P, Gerard CJ, et al. Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway. Mol Ther 2004; 10(6): 990-1002.
-
(2004)
Mol Ther
, vol.10
, Issue.6
, pp. 990-1002
-
-
Zhang, L.N.1
Karp, P.2
Gerard, C.J.3
-
76
-
-
0034756451
-
Expanding AAV packaging capacity with trans-splicing or overlapping vectors: A quantitative comparison
-
Duan D, Yue Y, Engelhardt JF. Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison. Mol Ther 2001; 4(4): 383-91.
-
(2001)
Mol Ther
, vol.4
, Issue.4
, pp. 383-391
-
-
Duan, D.1
Yue, Y.2
Engelhardt, J.F.3
-
77
-
-
0035989639
-
Efficient mouse airway transduction following recombination between AAV vectors carrying parts of a larger gene
-
Halbert CL, Allen JM, Miller AD. Efficient mouse airway transduction following recombination between AAV vectors carrying parts of a larger gene. Nat Biotechnol 2002; 20(7): 697-701.
-
(2002)
Nat Biotechnol
, vol.20
, Issue.7
, pp. 697-701
-
-
Halbert, C.L.1
Allen, J.M.2
Miller, A.D.3
-
78
-
-
62549141507
-
Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing
-
Song Y, Lou HH, Boyer JL, et al. Functional cystic fibrosis transmembrane conductance regulator expression in cystic fibrosis airway epithelial cells by AAV6.2-mediated segmental trans-splicing. Hum Gene Ther 2009; 20(3): 267-81.
-
(2009)
Hum Gene Ther
, vol.20
, Issue.3
, pp. 267-281
-
-
Song, Y.1
Lou, H.H.2
Boyer, J.L.3
-
79
-
-
20044381100
-
A shortened adenoassociated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia
-
Ostedgaard LS, Rokhlina T, Karp PH, et al. A shortened adenoassociated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia. Proc Natl Acad Sci USA 2005; 102(8): 2952-7.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.8
, pp. 2952-2957
-
-
Ostedgaard, L.S.1
Rokhlina, T.2
Karp, P.H.3
-
80
-
-
33947255488
-
Expression of a truncated cystic fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates
-
Fischer AC, Smith CI, Cebotaru L, et al. Expression of a truncated cystic fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates. Mol Ther 2007; 15(4): 756-63.
-
(2007)
Mol Ther
, vol.15
, Issue.4
, pp. 756-763
-
-
Fischer, A.C.1
Smith, C.I.2
Cebotaru, L.3
-
81
-
-
38349091329
-
Partial correction of the CFTR-dependent ABPA mouse model with recombinant adenoassociated virus gene transfer of truncated CFTR gene
-
Mueller C, Torrez D, Braag S, et al. Partial correction of the CFTR-dependent ABPA mouse model with recombinant adenoassociated virus gene transfer of truncated CFTR gene. J Gene Med 2008; 10(1): 51-60.
-
(2008)
J Gene Med
, vol.10
, Issue.1
, pp. 51-60
-
-
Mueller, C.1
Torrez, D.2
Braag, S.3
-
82
-
-
43049119982
-
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice
-
Allocca M, Doria M, Petrillo M, et al. Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice. J Clin Invest 2008; 118(5): 1955-64.
-
(2008)
J Clin Invest
, vol.118
, Issue.5
, pp. 1955-1964
-
-
Allocca, M.1
Doria, M.2
Petrillo, M.3
-
83
-
-
34248194614
-
High-efficiency promoterdependent transduction by adeno-associated virus type 6 vectors in mouse lung
-
Halbert CL, Lam SL, Miller AD. High-efficiency promoterdependent transduction by adeno-associated virus type 6 vectors in mouse lung. Hum Gene Ther 2007; 18(4): 344-54.
-
(2007)
Hum Gene Ther
, vol.18
, Issue.4
, pp. 344-354
-
-
Halbert, C.L.1
Lam, S.L.2
Miller, A.D.3
-
84
-
-
0032853032
-
Repeated delivery of adenoassociated virus vectors to the rabbit airway
-
Beck SE, Jones LA, Chesnut K, et al. Repeated delivery of adenoassociated virus vectors to the rabbit airway. J Virol 1999; 73(11): 9446-55.
-
(1999)
J Virol
, vol.73
, Issue.11
, pp. 9446-9455
-
-
Beck, S.E.1
Jones, L.A.2
Chesnut, K.3
-
85
-
-
0030795691
-
Transduction by adeno-associated virus vectors in the rabbit airway: Efficiency, persistence, and readministration
-
Halbert CL, Standaert TA, Aitken ML, Alexander IE, Russell DW, Miller AD. Transduction by adeno-associated virus vectors in the rabbit airway: efficiency, persistence, and readministration. J Virol 1997; 71(8): 5932-41.
-
(1997)
J Virol
, vol.71
, Issue.8
, pp. 5932-5941
-
-
Halbert, C.L.1
Standaert, T.A.2
Aitken, M.L.3
Alexander, I.E.4
Russell, D.W.5
Miller, A.D.6
-
86
-
-
0033960160
-
Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes
-
Halbert CL, Rutledge EA, Allen JM, Russell DW, Miller AD. Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes. J Virol 2000; 74(3): 1524-32.
-
(2000)
J Virol
, vol.74
, Issue.3
, pp. 1524-1532
-
-
Halbert, C.L.1
Rutledge, E.A.2
Allen, J.M.3
Russell, D.W.4
Miller, A.D.5
-
87
-
-
0036677468
-
Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins
-
Auricchio A, O'Connor E, Weiner D, et al. Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins. J Clin Invest 2002; 110(4): 499-504.
-
(2002)
J Clin Invest
, vol.110
, Issue.4
, pp. 499-504
-
-
Auricchio, A.1
O'Connor, E.2
Weiner, D.3
-
88
-
-
0346656769
-
Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques
-
Fischer AC, Beck SE, Smith CI, et al. Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques. Mol Ther 2003; 8(6): 918-26.
-
(2003)
Mol Ther
, vol.8
, Issue.6
, pp. 918-926
-
-
Fischer, A.C.1
Beck, S.E.2
Smith, C.I.3
-
89
-
-
77953128609
-
Expression of human alpha1-antitrypsin in mice and dogs following AAV6 vectormediated gene transfer to the lungs
-
Halbert CL, Madtes DK, Vaughan AE, et al. Expression of human alpha1-antitrypsin in mice and dogs following AAV6 vectormediated gene transfer to the lungs. Mol Ther 2010; 18(6): 1165-72.
-
(2010)
Mol Ther
, vol.18
, Issue.6
, pp. 1165-1172
-
-
Halbert, C.L.1
Madtes, D.K.2
Vaughan, A.E.3
-
90
-
-
63649130139
-
Analysis of adeno-associated virus progenitor cell transduction in mouse lung
-
Liu X, Luo M, Guo C, et al. Analysis of adeno-associated virus progenitor cell transduction in mouse lung. Mol Ther 2009; 17(2): 285-93.
-
(2009)
Mol Ther
, vol.17
, Issue.2
, pp. 285-293
-
-
Liu, X.1
Luo, M.2
Guo, C.3
-
91
-
-
77952425348
-
IL-10 delivery by AAV5 vector attenuates inflammation in mice with pseudomonas pneumonia
-
Buff SM, Yu H, McCall JN, et al. IL-10 delivery by AAV5 vector attenuates inflammation in mice with pseudomonas pneumonia. Gene Ther 2010; 17(5): 567-76.
-
(2010)
Gene Ther
, vol.17
, Issue.5
, pp. 567-576
-
-
Buff, S.M.1
Yu, H.2
McCall, J.N.3
-
92
-
-
76749131499
-
In vitro and in vivo functional characterization of gutless recombinant SV40-derived CFTR vectors
-
Mueller C, Strayer MS, Sirninger J, et al. In vitro and in vivo functional characterization of gutless recombinant SV40-derived CFTR vectors. Gene Ther 2010; 17(2): 227-37.
-
(2010)
Gene Ther
, vol.17
, Issue.2
, pp. 227-237
-
-
Mueller, C.1
Strayer, M.S.2
Sirninger, J.3
-
93
-
-
0031834248
-
Use of SV40 to immunize against hepatitis B surface antigen: Implications for the use of SV40 for gene transduction and its use as an immunizing agent
-
Kondo R, Feitelson MA, Strayer DS. Use of SV40 to immunize against hepatitis B surface antigen: implications for the use of SV40 for gene transduction and its use as an immunizing agent. Gene Ther 1998; 5(5): 575-82.
-
(1998)
Gene Ther
, vol.5
, Issue.5
, pp. 575-582
-
-
Kondo, R.1
Feitelson, M.A.2
Strayer, D.S.3
-
94
-
-
11144227707
-
Infection of ciliated cells by human parainfluenza virus type 3 in an in vitro model of human airway epithelium
-
Zhang L, Bukreyev A, Thompson CI, et al. Infection of ciliated cells by human parainfluenza virus type 3 in an in vitro model of human airway epithelium. J Virol 2005; 79(2): 1113-24.
-
(2005)
J Virol
, vol.79
, Issue.2
, pp. 1113-1124
-
-
Zhang, L.1
Bukreyev, A.2
Thompson, C.I.3
-
95
-
-
77954514975
-
Respiratory syncytial virus engineered to express the cystic fibrosis transmembrane conductance regulator corrects the bioelectric phenotype of human cystic fibrosis airway epithelium in vitro
-
Kwilas AR, Yednak MA, Zhang L, et al. Respiratory syncytial virus engineered to express the cystic fibrosis transmembrane conductance regulator corrects the bioelectric phenotype of human cystic fibrosis airway epithelium in vitro. J Virol 2010; 84(15): 7770-81.
-
(2010)
J Virol
, vol.84
, Issue.15
, pp. 7770-7781
-
-
Kwilas, A.R.1
Yednak, M.A.2
Zhang, L.3
-
96
-
-
0027164674
-
Sendai virus-induced cell fusion
-
Okada Y. Sendai virus-induced cell fusion. Methods Enzymol 1993; 221: 18-41.
-
(1993)
Methods Enzymol
, vol.221
, pp. 18-41
-
-
Okada, Y.1
-
97
-
-
34548730279
-
Sendai virus-mediated CFTR gene transfer to the airway epithelium
-
Ferrari S, Griesenbach U, Iida A, et al. Sendai virus-mediated CFTR gene transfer to the airway epithelium. Gene Ther 2007; 14(19): 1371-9.
-
(2007)
Gene Ther
, vol.14
, Issue.19
, pp. 1371-1379
-
-
Ferrari, S.1
Griesenbach, U.2
Iida, A.3
-
98
-
-
0036166302
-
The nasal epithelium as a factory for systemic protein delivery
-
Griesenbach U, Cassady RL, Ferrari S, et al. The nasal epithelium as a factory for systemic protein delivery. Mol Ther 2002; 5(2): 98-103.
-
(2002)
Mol Ther
, vol.5
, Issue.2
, pp. 98-103
-
-
Griesenbach, U.1
Cassady, R.L.2
Ferrari, S.3
-
99
-
-
0033947169
-
A cytoplasmic RNA vector derived from nontransmissible Sendai virus with efficient gene transfer and expression
-
Li HO, Zhu YF, Asakawa M, et al. A cytoplasmic RNA vector derived from nontransmissible Sendai virus with efficient gene transfer and expression. J Virol 2000; 74(14): 6564-9.
-
(2000)
J Virol
, vol.74
, Issue.14
, pp. 6564-6569
-
-
Li, H.O.1
Zhu, Y.F.2
Asakawa, M.3
-
100
-
-
0037370625
-
Nontransmissible virus-like particle formation by F-deficient sendai virus is temperature sensitive and reduced by mutations in M and HN proteins
-
Inoue M, Tokusumi Y, Ban H, et al. Nontransmissible virus-like particle formation by F-deficient sendai virus is temperature sensitive and reduced by mutations in M and HN proteins. J Virol 2003; 77(5): 3238-46.
-
(2003)
J Virol
, vol.77
, Issue.5
, pp. 3238-3246
-
-
Inoue, M.1
Tokusumi, Y.2
Ban, H.3
-
101
-
-
33745755929
-
Gene therapy progress and prospects: Cystic fibrosis
-
Griesenbach U, Geddes DM, Alton EW. Gene therapy progress and prospects: cystic fibrosis. Gene Ther 2006; 13(14): 1061-7.
-
(2006)
Gene Ther
, vol.13
, Issue.14
, pp. 1061-1067
-
-
Griesenbach, U.1
Geddes, D.M.2
Alton, E.W.3
-
102
-
-
47249101463
-
HVJ envelope vector, a versatile delivery system: Its development, application, and perspectives
-
Zhang Q, Li Y, Shi Y, Zhang Y. HVJ envelope vector, a versatile delivery system: its development, application, and perspectives. Biochem Biophys Res Commun 2008; 373(3): 345-9.
-
(2008)
Biochem Biophys Res Commun
, vol.373
, Issue.3
, pp. 345-349
-
-
Zhang, Q.1
Li, Y.2
Shi, Y.3
Zhang, Y.4
-
103
-
-
0036664449
-
Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system
-
Kaneda Y, Nakajima T, Nishikawa T, et al. Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system. Mol Ther 2002; 6(2): 219-26.
-
(2002)
Mol Ther
, vol.6
, Issue.2
, pp. 219-226
-
-
Kaneda, Y.1
Nakajima, T.2
Nishikawa, T.3
-
104
-
-
70450265981
-
Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
-
Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 2009; 85(8): 348-62.
-
(2009)
Proc Jpn Acad Ser B Phys Biol Sci
, vol.85
, Issue.8
, pp. 348-362
-
-
Fusaki, N.1
Ban, H.2
Nishiyama, A.3
Saeki, K.4
Hasegawa, M.5
-
105
-
-
77957671713
-
Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells
-
Seki T, Yuasa S, Oda M, et al. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 2010; 7(1): 11-4.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.1
, pp. 11-14
-
-
Seki, T.1
Yuasa, S.2
Oda, M.3
-
106
-
-
37349084579
-
CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector
-
Rakonczay Z, Jr., Hegyi P, Hasegawa M, et al. CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector. J Cell Physiol 2008; 214(2): 442-55.
-
(2008)
J Cell Physiol
, vol.214
, Issue.2
, pp. 442-455
-
-
Rakonczay Jr., Z.1
Hegyi, P.2
Hasegawa, M.3
-
107
-
-
71049152079
-
CFTR expression but not Cl-transport is involved in the stimulatory effect of bile acids on apical Cl-/
-
Ignath I, Hegyi P, Venglovecz V, et al. CFTR expression but not Cl-transport is involved in the stimulatory effect of bile acids on apical Cl-/. Pancreas 2009; 38(8): 921-9.
-
(2009)
Pancreas
, vol.38
, Issue.8
, pp. 921-929
-
-
Ignath, I.1
Hegyi, P.2
Venglovecz, V.3
-
108
-
-
0027099652
-
In vivo retroviral gene transfer into human bronchial epithelia of xenografts
-
Engelhardt JF, Yankaskas JR, Wilson JM. In vivo retroviral gene transfer into human bronchial epithelia of xenografts. J Clin Invest 1992; 90(6): 2598-607.
-
(1992)
J Clin Invest
, vol.90
, Issue.6
, pp. 2598-2607
-
-
Engelhardt, J.F.1
Yankaskas, J.R.2
Wilson, J.M.3
-
109
-
-
0037320020
-
Pseudotyped lentivirus vectors derived from simian immunodeficiency virus SIVagm with envelope glycoproteins from paramyxovirus
-
Kobayashi M, Iida A, Ueda Y, Hasegawa M. Pseudotyped lentivirus vectors derived from simian immunodeficiency virus SIVagm with envelope glycoproteins from paramyxovirus. J Virol 2003; 77(4): 2607-14.
-
(2003)
J Virol
, vol.77
, Issue.4
, pp. 2607-2614
-
-
Kobayashi, M.1
Iida, A.2
Ueda, Y.3
Hasegawa, M.4
-
110
-
-
77953138185
-
Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes
-
Mitomo K, Griesenbach U, Inoue M, et al. Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes. Mol Ther 2010; 18(6): 1173-82.
-
(2010)
Mol Ther
, vol.18
, Issue.6
, pp. 1173-1182
-
-
Mitomo, K.1
Griesenbach, U.2
Inoue, M.3
-
111
-
-
55249121439
-
Lentivirus vector can be readministered to nasal epithelia without blocking immune responses
-
Sinn PL, Arias AC, Brogden KA, McCray PB, Jr. Lentivirus vector can be readministered to nasal epithelia without blocking immune responses. J Virol 2008; 82(21): 10684-92.
-
(2008)
J Virol
, vol.82
, Issue.21
, pp. 10684-10692
-
-
Sinn, P.L.1
Arias, A.C.2
Brogden, K.A.3
McCray Jr., P.B.4
-
112
-
-
33645767668
-
Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors
-
McKay T, Patel M, Pickles RJ, Johnson LG, Olsen JC. Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors. Gene Ther 2006; 13(8): 715-24.
-
(2006)
Gene Ther
, vol.13
, Issue.8
, pp. 715-724
-
-
McKay, T.1
Patel, M.2
Pickles, R.J.3
Johnson, L.G.4
Olsen, J.C.5
-
113
-
-
22744455256
-
Gene therapy progress and prospects: Development of improved lentiviral and retroviral vectors-- design, biosafety, and production
-
Sinn PL, Sauter SL, McCray PB, Jr. Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors-- design, biosafety, and production. Gene Ther 2005; 12(14): 1089-98.
-
(2005)
Gene Ther
, vol.12
, Issue.14
, pp. 1089-1098
-
-
Sinn, P.L.1
Sauter, S.L.2
McCray Jr., P.B.3
-
114
-
-
0036431592
-
Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer
-
Limberis M, Anson DS, Fuller M, Parsons DW. Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer. Hum Gene Ther 2002; 13(16): 1961-70.
-
(2002)
Hum Gene Ther
, vol.13
, Issue.16
, pp. 1961-1970
-
-
Limberis, M.1
Anson, D.S.2
Fuller, M.3
Parsons, D.W.4
-
115
-
-
77956667210
-
Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: Effect of acyl chain length
-
Cmielewski P, Anson DS, Parsons DW. Lysophosphatidylcholine as an adjuvant for lentiviral vector mediated gene transfer to airway epithelium: effect of acyl chain length. Respir Res 2010; 11(1): 84.
-
(2010)
Respir Res
, vol.11
, Issue.1
, pp. 84
-
-
Cmielewski, P.1
Anson, D.S.2
Parsons, D.W.3
-
116
-
-
0347503527
-
Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung
-
Medina MF, Kobinger GP, Rux J, et al. Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung. Mol Ther 2003; 8(5): 777-89.
-
(2003)
Mol Ther
, vol.8
, Issue.5
, pp. 777-789
-
-
Medina, M.F.1
Kobinger, G.P.2
Rux, J.3
-
117
-
-
72449166602
-
Single-dose lentiviral gene transfer for lifetime airway gene expression
-
Stocker AG, Kremer KL, Koldej R, Miller DS, Anson DS, Parsons DW. Single-dose lentiviral gene transfer for lifetime airway gene expression. J Gene Med 2009; 11(10): 861-7.
-
(2009)
J Gene Med
, vol.11
, Issue.10
, pp. 861-867
-
-
Stocker, A.G.1
Kremer, K.L.2
Koldej, R.3
Miller, D.S.4
Anson, D.S.5
Parsons, D.W.6
-
118
-
-
49049114350
-
Ciliated epithelial cell lifespan in the mouse trachea and lung
-
Rawlins EL, Hogan BL. Ciliated epithelial cell lifespan in the mouse trachea and lung. Am J Physiol Lung Cell Mol Physiol 2008; 295(1): L231-L234.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
, Issue.1
-
-
Rawlins, E.L.1
Hogan, B.L.2
-
119
-
-
84889752335
-
Repeat Administration of Sendai Virus-F/HN Pseudotyped Lentivirus Vector to the Respiratory Epithelium is Feasible
-
Ref Type: Abstract
-
Griesenbach U, Mitomo K, Inoue M, et al. Repeat Administration of Sendai Virus-F/HN Pseudotyped Lentivirus Vector to the Respiratory Epithelium is Feasible. Mol.Ther. 1[16]. 2008. Ref Type: Abstract
-
(2008)
Mol.Ther
, vol.1
, Issue.16
-
-
Griesenbach, U.1
Mitomo, K.2
Inoue, M.3
-
120
-
-
39049108336
-
-
[website on the internet]. Available from
-
UK Cystic Fibrosis Gene Therapy Consortium. [website on the internet]. Available from: http://www.cfgenetherapy.org.uk
-
UK Cystic Fibrosis Gene Therapy Consortium
-
-
-
121
-
-
51349158298
-
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
-
Howe SJ, Mansour MR, Schwarzwaelder K, et al. Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients. J Clin Invest 2008; 118(9): 3143-50.
-
(2008)
J Clin Invest
, vol.118
, Issue.9
, pp. 3143-3150
-
-
Howe, S.J.1
Mansour, M.R.2
Schwarzwaelder, K.3
-
122
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R, Dull T, Mandel RJ, et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 1998; 72(12): 9873-80.
-
(1998)
J Virol
, vol.72
, Issue.12
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
-
123
-
-
65249101260
-
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
-
Montini E, Cesana D, Schmidt M, et al. The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy. J Clin Invest 2009; 119(4): 964-75.
-
(2009)
J Clin Invest
, vol.119
, Issue.4
, pp. 964-975
-
-
Montini, E.1
Cesana, D.2
Schmidt, M.3
-
124
-
-
68249112926
-
Integration-deficient lentiviral vectors: A slow coming of age
-
Wanisch K, Yanez-Munoz RJ. Integration-deficient lentiviral vectors: a slow coming of age. Mol Ther 2009; 17(8): 1316-32.
-
(2009)
Mol Ther
, vol.17
, Issue.8
, pp. 1316-1332
-
-
Wanisch, K.1
Yanez-Munoz, R.J.2
-
125
-
-
64649102398
-
Site-specific integration of retroviral DNA in human cells using fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc-finger protein E2C
-
Su K, Wang D, Ye J, Kim YC, Chow SA. Site-specific integration of retroviral DNA in human cells using fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc-finger protein E2C. Methods 2009; 47(4): 269-76.
-
(2009)
Methods
, vol.47
, Issue.4
, pp. 269-276
-
-
Su, K.1
Wang, D.2
Ye, J.3
Kim, Y.C.4
Chow, S.A.5
-
126
-
-
64749107970
-
Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors
-
Kutner RH, Zhang XY, Reiser J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nat Protoc 2009; 4(4): 495-505.
-
(2009)
Nat Protoc
, vol.4
, Issue.4
, pp. 495-505
-
-
Kutner, R.H.1
Zhang, X.Y.2
Reiser, J.3
-
127
-
-
0038333587
-
Continuous high-titer HIV-1 vector production
-
Ikeda Y, Takeuchi Y, Martin F, Cosset FL, Mitrophanous K, Collins M. Continuous high-titer HIV-1 vector production. Nat Biotechnol 2003; 21(5): 569-72.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.5
, pp. 569-572
-
-
Ikeda, Y.1
Takeuchi, Y.2
Martin, F.3
Cosset, F.L.4
Mitrophanous, K.5
Collins, M.6
-
128
-
-
77950606953
-
The Adaptive Aerosol Delivery (AAD) technology: Past, present, and future
-
Denyer J, Dyche T. The Adaptive Aerosol Delivery (AAD) technology: Past, present, and future. J Aerosol Med Pulm Drug Deliv 2010; 23 Suppl 1: S1-10.
-
(2010)
J Aerosol Med Pulm Drug Deliv
, vol.23
, Issue.SUPPL. 1
-
-
Denyer, J.1
Dyche, T.2
-
129
-
-
0036797279
-
Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques
-
Beck SE, Laube BL, Barberena CI, et al. Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques. Mol Ther 2002; 6(4): 546-54.
-
(2002)
Mol Ther
, vol.6
, Issue.4
, pp. 546-554
-
-
Beck, S.E.1
Laube, B.L.2
Barberena, C.I.3
-
130
-
-
48949105555
-
Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression
-
Buckley SM, Howe SJ, Sheard V, et al. Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression. Gene Ther 2008; 15(16): 1167-75.
-
(2008)
Gene Ther
, vol.15
, Issue.16
, pp. 1167-1175
-
-
Buckley, S.M.1
Howe, S.J.2
Sheard, V.3
-
131
-
-
79251484053
-
Genetic Modification of Airway Progenitors Following Lentiviral Gene Delivery to the Amniotic Fluid of Murine Fetuses
-
Mishra S, Wang X, Smiley N, et al. Genetic Modification of Airway Progenitors Following Lentiviral Gene Delivery to the Amniotic Fluid of Murine Fetuses. Am J Respir Cell Mol Biol 2010 Jun 25.
-
(2010)
Am J Respir Cell Mol Biol
, pp. 25
-
-
Mishra, S.1
Wang, X.2
Smiley, N.3
-
132
-
-
74949132576
-
Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages
-
Wilson AA, Murphy GJ, Hamakawa H, et al. Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. J Clin Invest 2010; 120(1): 379-89.
-
(2010)
J Clin Invest
, vol.120
, Issue.1
, pp. 379-389
-
-
Wilson, A.A.1
Murphy, G.J.2
Hamakawa, H.3
-
133
-
-
33846907545
-
Alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients
-
Griese M, Latzin P, Kappler M, et al. alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients. Eur Respir J 2007; 29(2): 240-50.
-
(2007)
Eur Respir J
, vol.29
, Issue.2
, pp. 240-250
-
-
Griese, M.1
Latzin, P.2
Kappler, M.3
-
134
-
-
62249100734
-
Short hairpin RNAs against eotaxin or interleukin-5 decrease airway eosinophilia and hyperresponsiveness in a murine model of asthma
-
Huang HY, Lee CC, Chiang BL. Short hairpin RNAs against eotaxin or interleukin-5 decrease airway eosinophilia and hyperresponsiveness in a murine model of asthma. J Gene Med 2009; 11(2): 112-8.
-
(2009)
J Gene Med
, vol.11
, Issue.2
, pp. 112-118
-
-
Huang, H.Y.1
Lee, C.C.2
Chiang, B.L.3
-
135
-
-
77953953690
-
Lentiviral vector-mediated expression of pre-miRNAs and antagomiRs
-
Scherr M, Venturini L, Eder M. Lentiviral vector-mediated expression of pre-miRNAs and antagomiRs. Methods Mol Biol 2010; 614: 175-85.
-
(2010)
Methods Mol Biol
, vol.614
, pp. 175-185
-
-
Scherr, M.1
Venturini, L.2
Eder, M.3
-
136
-
-
2442718786
-
Increased airway epithelial Na+ absorption produces cystic fibrosislike lung disease in mice
-
Mall M, Grubb BR, Harkema JR, O'Neal WK, Boucher RC. Increased airway epithelial Na+ absorption produces cystic fibrosislike lung disease in mice. Nat Med 2004; 10(5): 487-93.
-
(2004)
Nat Med
, vol.10
, Issue.5
, pp. 487-493
-
-
Mall, M.1
Grubb, B.R.2
Harkema, J.R.3
O'Neal, W.K.4
Boucher, R.C.5
-
137
-
-
27944483003
-
Mutations in the betasubunit of the epithelial Na+ channel in patients with a cystic fibrosis-like syndrome
-
Sheridan MB, Fong P, Groman JD, et al. Mutations in the betasubunit of the epithelial Na+ channel in patients with a cystic fibrosis-like syndrome. Hum Mol Genet 2005; 14(22): 3493-8.
-
(2005)
Hum Mol Genet
, vol.14
, Issue.22
, pp. 3493-3498
-
-
Sheridan, M.B.1
Fong, P.2
Groman, J.D.3
-
138
-
-
33745759579
-
Endpoint assay development and validation of non-viral gene transfer agents in CF mice
-
Ref Type: Abstract
-
Griesenbach U, Wasowicz MY, Smith SN, et al. Endpoint assay development and validation of non-viral gene transfer agents in CF mice. Ped.Pulm. S28. 2005. Ref Type: Abstract
-
(2005)
Ped.Pulm
-
-
Griesenbach, U.1
Wasowicz, M.Y.2
Smith, S.N.3
-
139
-
-
77957343707
-
Chemical vectors for gene delivery: Uptake and intracellular trafficking
-
Pichon C, Billiet L, Midoux P. Chemical vectors for gene delivery: uptake and intracellular trafficking. Curr Opin Biotechnol 2010; 21(5): 640-5.
-
(2010)
Curr Opin Biotechnol
, vol.21
, Issue.5
, pp. 640-645
-
-
Pichon, C.1
Billiet, L.2
Midoux, P.3
-
140
-
-
0036222250
-
Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor
-
Ziady AG, Kelley TJ, Milliken E, Ferkol T, Davis PB. Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme complex receptor. Mol Ther 2002; 5(4): 413-9.
-
(2002)
Mol Ther
, vol.5
, Issue.4
, pp. 413-419
-
-
Ziady, A.G.1
Kelley, T.J.2
Milliken, E.3
Ferkol, T.4
Davis, P.B.5
-
141
-
-
42549138758
-
A receptor-targeted nanocomplex vector system optimized for respiratory gene transfer
-
Tagalakis AD, McAnulty RJ, Devaney J, et al. A receptor-targeted nanocomplex vector system optimized for respiratory gene transfer. Mol Ther 2008; 16(5): 907-15.
-
(2008)
Mol Ther
, vol.16
, Issue.5
, pp. 907-915
-
-
Tagalakis, A.D.1
McAnulty, R.J.2
Devaney, J.3
-
142
-
-
45749158576
-
Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes
-
Davies LA, McLachlan G, Sumner-Jones SG, et al. Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes. Mol Ther 2008; 16(7): 1283-90.
-
(2008)
Mol Ther
, vol.16
, Issue.7
, pp. 1283-1290
-
-
Davies, L.A.1
McLachlan, G.2
Sumner-Jones, S.G.3
-
143
-
-
33847040423
-
Gene transfer of hepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis
-
Gazdhar A, Fachinger P, van LC, et al. Gene transfer of hepatocyte growth factor by electroporation reduces bleomycin-induced lung fibrosis. Am J Physiol Lung Cell Mol Physiol 2007; 292(2): L529-L536.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
, Issue.2
-
-
Gazdhar, A.1
Fachinger, P.2
Van, L.C.3
-
144
-
-
34548619402
-
Electroporationmediated gene transfer of the Na+,K+ -ATPase rescues endotoxininduced lung injury
-
Mutlu GM, hado-Aranda D, Norton JE, et al. Electroporationmediated gene transfer of the Na+,K+ -ATPase rescues endotoxininduced lung injury. Am J Respir Crit Care Med 2007; 176(6): 582-90.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, Issue.6
, pp. 582-590
-
-
Mutlu, G.M.1
Hado-Aranda, D.2
Norton, J.E.3
-
145
-
-
34249019015
-
Electroporation enhances reporter gene expression following delivery of naked plasmid DNA to the lung
-
Pringle IA, McLachlan G, Collie DD, et al. Electroporation enhances reporter gene expression following delivery of naked plasmid DNA to the lung. J Gene Med 2007; 9(5): 369-80.
-
(2007)
J Gene Med
, vol.9
, Issue.5
, pp. 369-380
-
-
Pringle, I.A.1
McLachlan, G.2
Collie, D.D.3
-
146
-
-
77956613069
-
Electroporation- and mechanical ventilation-mediated gene transfer to the lung
-
Kaufman CD, Geiger RC, Dean DA. Electroporation- and mechanical ventilation-mediated gene transfer to the lung. Gene Ther 2010; 17(9): 1098-104.
-
(2010)
Gene Ther
, vol.17
, Issue.9
, pp. 1098-1104
-
-
Kaufman, C.D.1
Geiger, R.C.2
Dean, D.A.3
-
147
-
-
33750015512
-
Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo
-
Xenariou S, Griesenbach U, Ferrari S, et al. Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo. Gene Ther 2006; 13(21): 1545-52.
-
(2006)
Gene Ther
, vol.13
, Issue.21
, pp. 1545-1552
-
-
Xenariou, S.1
Griesenbach, U.2
Ferrari, S.3
-
148
-
-
34247110877
-
Use of ultrasound to enhance nonviral lung gene transfer in vivo
-
Xenariou S, Griesenbach U, Liang HD, et al. Use of ultrasound to enhance nonviral lung gene transfer in vivo. Gene Ther 2007; 14(9): 768-74.
-
(2007)
Gene Ther
, vol.14
, Issue.9
, pp. 768-774
-
-
Xenariou, S.1
Griesenbach, U.2
Liang, H.D.3
-
149
-
-
73549107419
-
Low-frequency ultrasound increases non-viral gene transfer to the mouse lung
-
Xenariou S, Liang HD, Griesenbach U, et al. Low-frequency ultrasound increases non-viral gene transfer to the mouse lung. Acta Biochim Biophys Sin (Shanghai) 2010; 42(1): 45-51.
-
(2010)
Acta Biochim Biophys Sin (Shanghai)
, vol.42
, Issue.1
, pp. 45-51
-
-
Xenariou, S.1
Liang, H.D.2
Griesenbach, U.3
-
150
-
-
59649105951
-
The role of doxorubicin in non-viral gene transfer in the lung
-
Griesenbach U, Meng C, Farley R, et al. The role of doxorubicin in non-viral gene transfer in the lung. Biomaterials 2009; 30(10): 1971-7.
-
(2009)
Biomaterials
, vol.30
, Issue.10
, pp. 1971-1977
-
-
Griesenbach, U.1
Meng, C.2
Farley, R.3
-
151
-
-
43449111490
-
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
-
Hyde SC, Pringle IA, Abdullah S, et al. CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression. Nat Biotechnol 2008; 26(5): 549-51.
-
(2008)
Nat Biotechnol
, vol.26
, Issue.5
, pp. 549-551
-
-
Hyde, S.C.1
Pringle, I.A.2
Abdullah, S.3
-
152
-
-
70350351352
-
Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import
-
Munkonge FM, Amin V, Hyde SC, et al. Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import. J Biol Chem 2009; 284(39): 26978-87.
-
(2009)
J Biol Chem
, vol.284
, Issue.39
, pp. 26978-26987
-
-
Munkonge, F.M.1
Amin, V.2
Hyde, S.C.3
-
154
-
-
60449098993
-
Progress and prospects: The design and production of plasmid vectors
-
Gill DR, Pringle IA, Hyde SC. Progress and prospects: the design and production of plasmid vectors. Gene Ther 2009; 16(2): 165-71.
-
(2009)
Gene Ther
, vol.16
, Issue.2
, pp. 165-171
-
-
Gill, D.R.1
Pringle, I.A.2
Hyde, S.C.3
-
155
-
-
79951882496
-
Transgene Loss and Changes in the Promoter Methylation Status as Determinants for Expression Duration in Nonviral Gene Transfer for Factor IX
-
Schuttrumpf J, Milanov P, Abriss D, Roth S, Tonn T, Seifried E. Transgene Loss and Changes in the Promoter Methylation Status as Determinants for Expression Duration in Nonviral Gene Transfer for Factor IX. Hum Gene Ther 2011; 22(1): 101-6.
-
(2011)
Hum Gene Ther
, vol.22
, Issue.1
, pp. 101-106
-
-
Schuttrumpf, J.1
Milanov, P.2
Abriss, D.3
Roth, S.4
Tonn, T.5
Seifried, E.6
-
156
-
-
58149193835
-
Minicircle- DNA production by site specific recombination and protein-DNA interaction chromatography
-
Mayrhofer P, Blaesen M, Schleef M, Jechlinger W. Minicircle- DNA production by site specific recombination and protein-DNA interaction chromatography. J Gene Med 2008; 10(11): 1253-69.
-
(2008)
J Gene Med
, vol.10
, Issue.11
, pp. 1253-1269
-
-
Mayrhofer, P.1
Blaesen, M.2
Schleef, M.3
Jechlinger, W.4
-
157
-
-
47049085173
-
Stem cells and cell therapies for cystic fibrosis and other lung diseases
-
Weiss DJ. Stem cells and cell therapies for cystic fibrosis and other lung diseases. Pulm Pharmacol Ther 2008; 21(4): 588-94.
-
(2008)
Pulm Pharmacol Ther
, vol.21
, Issue.4
, pp. 588-594
-
-
Weiss, D.J.1
-
158
-
-
61749097005
-
Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium
-
Wong AP, Keating A, Lu WY, et al. Identification of a bone marrow-derived epithelial-like population capable of repopulating injured mouse airway epithelium. J Clin Invest 2009; 119(2): 336-48.
-
(2009)
J Clin Invest
, vol.119
, Issue.2
, pp. 336-348
-
-
Wong, A.P.1
Keating, A.2
Lu, W.Y.3
-
159
-
-
19944427214
-
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: Potential therapy for cystic fibrosis
-
Wang G, Bunnell BA, Painter RG, et al. Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc Natl Acad Sci USA; 102(1): 186-91.
-
Proc Natl Acad Sci USA
, vol.102
, Issue.1
, pp. 186-191
-
-
Wang, G.1
Bunnell, B.A.2
Painter, R.G.3
-
161
-
-
33644501073
-
Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation
-
Bruscia EM, Price JE, Cheng EC, et al. Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation. Proc Natl Acad Sci USA 2006; 103(8): 2965-70.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.8
, pp. 2965-2970
-
-
Bruscia, E.M.1
Price, J.E.2
Cheng, E.C.3
-
162
-
-
31944451977
-
Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells
-
Loi R, Beckett T, Goncz KK, Suratt BT, Weiss DJ. Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells. Am J Respir Crit Care Med 2006; 173(2): 171-9.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, Issue.2
, pp. 171-179
-
-
Loi, R.1
Beckett, T.2
Goncz, K.K.3
Suratt, B.T.4
Weiss, D.J.5
-
163
-
-
67649861097
-
Engraftment of bone marrowderived stem cells to the lung in a model of acute respiratory infection by Pseudomonas aeruginosa
-
Rejman J, Colombo C, Conese M. Engraftment of bone marrowderived stem cells to the lung in a model of acute respiratory infection by Pseudomonas aeruginosa. Mol Ther 2009; 17(7): 1257-65.
-
(2009)
Mol Ther
, vol.17
, Issue.7
, pp. 1257-1265
-
-
Rejman, J.1
Colombo, C.2
Conese, M.3
-
164
-
-
77957566445
-
Optimization of targeted cell replacement therapy: A new approach for lung disease
-
Duchesneau P, Wong AP, Waddell TK. Optimization of targeted cell replacement therapy: a new approach for lung disease. Mol Ther 2010; 18(10): 1830-6.
-
(2010)
Mol Ther
, vol.18
, Issue.10
, pp. 1830-1836
-
-
Duchesneau, P.1
Wong, A.P.2
Waddell, T.K.3
-
165
-
-
77952856099
-
Effects of fibroblast growth factors on the differentiation of the pulmonary progenitors from murine embryonic stem cells
-
Lin YM, Zhang A, Bismarck A, Bishop AE. Effects of fibroblast growth factors on the differentiation of the pulmonary progenitors from murine embryonic stem cells. Exp Lung Res 2010; 36(5): 307-20.
-
(2010)
Exp Lung Res
, vol.36
, Issue.5
, pp. 307-320
-
-
Lin, Y.M.1
Zhang, A.2
Bismarck, A.3
Bishop, A.E.4
-
166
-
-
33646571869
-
Derivation of distal airway epithelium from human embryonic stem cells
-
Samadikuchaksaraei A, Cohen S, Isaac K, et al. Derivation of distal airway epithelium from human embryonic stem cells. Tissue Eng 2006; 12(4): 867-75.
-
(2006)
Tissue Eng
, vol.12
, Issue.4
, pp. 867-875
-
-
Samadikuchaksaraei, A.1
Cohen, S.2
Isaac, K.3
-
167
-
-
49449096770
-
Embryonic stem cells as a source of pulmonary epithelium in vitro and in vivo
-
Rippon HJ, Lane S, Qin M, et al. Embryonic stem cells as a source of pulmonary epithelium in vitro and in vivo. Proc Am Thorac Soc 2008; 5(6): 717-22.
-
(2008)
Proc Am Thorac Soc
, vol.5
, Issue.6
, pp. 717-722
-
-
Rippon, H.J.1
Lane, S.2
Qin, M.3
-
168
-
-
70449102888
-
Developing cell therapy techniques for respiratory disease: Intratracheal delivery of genetically engineered stem cells in a murine model of airway injury
-
Leblond AL, Naud P, Forest V, et al. Developing cell therapy techniques for respiratory disease: intratracheal delivery of genetically engineered stem cells in a murine model of airway injury. Hum Gene Ther 2009; 20(11): 1329-43.
-
(2009)
Hum Gene Ther
, vol.20
, Issue.11
, pp. 1329-1343
-
-
Leblond, A.L.1
Naud, P.2
Forest, V.3
-
169
-
-
77649267885
-
Transplantation of human embryonic stem cell-derived alveolar epithelial type II cells abrogates acute lung injury in mice
-
Wang D, Morales JE, Calame DG, Alcorn JL, Wetsel RA. Transplantation of human embryonic stem cell-derived alveolar epithelial type II cells abrogates acute lung injury in mice. Mol Ther 2010; 18(3): 625-34.
-
(2010)
Mol Ther
, vol.18
, Issue.3
, pp. 625-634
-
-
Wang, D.1
Morales, J.E.2
Calame, D.G.3
Alcorn, J.L.4
Wetsel, R.A.5
-
170
-
-
14944386646
-
Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis
-
Pickering SJ, Minger SL, Patel M, et al. Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis. Reprod Biomed Online 2005; 10(3): 390-7.
-
(2005)
Reprod Biomed Online
, vol.10
, Issue.3
, pp. 390-397
-
-
Pickering, S.J.1
Minger, S.L.2
Patel, M.3
-
171
-
-
77958082207
-
Generation of Transgene- Free Lung Disease-Specific Human iPS Cells Using a Single Excisable Lentiviral Stem Cell Cassette
-
Somers A, Jean JC, Sommer CA, et al. Generation of Transgene- Free Lung Disease-Specific Human iPS Cells Using a Single Excisable Lentiviral Stem Cell Cassette. Stem Cells 2010.
-
(2010)
Stem Cells
-
-
Somers, A.1
Jean, J.C.2
Sommer, C.A.3
-
172
-
-
34047108549
-
Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: A pilot randomized controlled trial
-
Wang XX, Zhang FR, Shang YP, et al. Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: a pilot randomized controlled trial. J Am Coll Cardiol 2007; 49(14): 1566-71.
-
(2007)
J Am Coll Cardiol
, vol.49
, Issue.14
, pp. 1566-1571
-
-
Wang, X.X.1
Zhang, F.R.2
Shang, Y.P.3
-
173
-
-
77649246501
-
Embryonic stem cells and repair of lung injury
-
Weiss DJ, Finck C. Embryonic stem cells and repair of lung injury. Mol Ther 2010; 18(3): 460-1.
-
(2010)
Mol Ther
, vol.18
, Issue.3
, pp. 460-461
-
-
Weiss, D.J.1
Finck, C.2
-
174
-
-
57349176894
-
Clinical transplantation of a tissue-engineered airway
-
Macchiarini P, Jungebluth P, Go T, et al. Clinical transplantation of a tissue-engineered airway. Lancet 2008; 372(9655): 2023-30.
-
(2008)
Lancet
, vol.372
, Issue.9655
, pp. 2023-2030
-
-
Macchiarini, P.1
Jungebluth, P.2
Go, T.3
-
175
-
-
77955115175
-
Tissue-engineered lungs for in vivo implantation
-
Petersen TH, Calle EA, Zhao L, et al. Tissue-engineered lungs for in vivo implantation. Science 2010; 329(5991): 538-41.
-
(2010)
Science
, vol.329
, Issue.5991
, pp. 538-541
-
-
Petersen, T.H.1
Calle, E.A.2
Zhao, L.3
-
176
-
-
69549089991
-
Cystic fibrosis-related diabetes: Current trends in prevalence, incidence, and mortality
-
Moran A, Dunitz J, Nathan B, Saeed A, Holme B, Thomas W. Cystic fibrosis-related diabetes: current trends in prevalence, incidence, and mortality. Diabetes Care 2009; 32(9): 1626-31.
-
(2009)
Diabetes Care
, vol.32
, Issue.9
, pp. 1626-1631
-
-
Moran, A.1
Dunitz, J.2
Nathan, B.3
Saeed, A.4
Holme, B.5
Thomas, W.6
-
177
-
-
79958047971
-
Combined pancreatic islet-lung transplantation: A novel approach to the treatment of endstage cystic fibrosis
-
Kessler L, Bakopoulou S, Kessler R, et al. Combined pancreatic islet-lung transplantation: a novel approach to the treatment of endstage cystic fibrosis. Am J Transplant 2010; 10(7): 1707-12.
-
(2010)
Am J Transplant
, vol.10
, Issue.7
, pp. 1707-1712
-
-
Kessler, L.1
Bakopoulou, S.2
Kessler, R.3
-
178
-
-
32544448208
-
Improving rate of decline of FEV1 in young adults with cystic fibrosis
-
Que C, Cullinan P, Geddes D. Improving rate of decline of FEV1 in young adults with cystic fibrosis. Thorax 2006; 61(2): 155-7.
-
(2006)
Thorax
, vol.61
, Issue.2
, pp. 155-157
-
-
Que, C.1
Cullinan, P.2
Geddes, D.3
-
179
-
-
34047166052
-
Airway surface dehydration in cystic fibrosis: Pathogenesis and therapy
-
Boucher RC. Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annu Rev Med 2007; 58: 157-70.
-
(2007)
Annu Rev Med
, vol.58
, pp. 157-170
-
-
Boucher, R.C.1
-
181
-
-
77952974496
-
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth
-
29ra31
-
Stoltz DA, Meyerholz DK, Pezzulo AA, et al. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Sci Transl Med 2010; 2(29): 29ra31.
-
(2010)
Sci Transl Med
, vol.2
, Issue.29
-
-
Stoltz, D.A.1
Meyerholz, D.K.2
Pezzulo, A.A.3
-
182
-
-
79952779452
-
The {Delta}F508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis-Like Disease in Pigs
-
74ra24
-
Ostedgaard LS, Meyerholz DK, Chen JH, et al. The {Delta}F508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis-Like Disease in Pigs. Sci Transl Med 2011; 3(74): 74ra24.
-
(2011)
Sci Transl Med
, vol.3
, Issue.74
-
-
Ostedgaard, L.S.1
Meyerholz, D.K.2
Chen, J.H.3
-
183
-
-
41849102053
-
Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets
-
Sun X, Yan Z, Yi Y, et al. Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets. J Clin Invest 2008; 118(4): 1578-83.
-
(2008)
J Clin Invest
, vol.118
, Issue.4
, pp. 1578-1583
-
-
Sun, X.1
Yan, Z.2
Yi, Y.3
-
184
-
-
79952764514
-
Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease
-
Kimura T, Kawabe H, Jiang C, et al. Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease. Proc Natl Acad Sci USA 2011; 108(8): 3216-21.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.8
, pp. 3216-3221
-
-
Kimura, T.1
Kawabe, H.2
Jiang, C.3
|