-
1
-
-
0020684648
-
Nucleotide sequence and organization of the adeno-associated virus 2 genome
-
Srivastava, A., Lusby, E.W. & Berns, K.I. Nucleotide sequence and organization of the adeno-associated virus 2 genome. J. Virol. 45, 555-564 (1983).
-
(1983)
J. Virol.
, vol.45
, pp. 555-564
-
-
Srivastava, A.1
Lusby, E.W.2
Berns, K.I.3
-
2
-
-
0032959311
-
Cloning and characterization of adenoassociated virus type 5
-
Chiorini, J.A., Kim, F., Yang, L. & Kotin, R.M. Cloning and characterization of adenoassociated virus type 5. J. Virol. 73, 1309-1319 (1999).
-
(1999)
J. Virol.
, vol.73
, pp. 1309-1319
-
-
Chiorini, J.A.1
Kim, F.2
Yang, L.3
Kotin, R.M.4
-
3
-
-
0034724209
-
Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system
-
Davidson, B.L. et al. Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system. Proc. Natl. Acad. Sci. USA 97, 3428-3432 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3428-3432
-
-
Davidson, B.L.1
-
4
-
-
0037015049
-
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
-
Gao, G.P. et al. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc. Natl. Acad. Sci. USA 99, 11854-11859 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11854-11859
-
-
Gao, G.P.1
-
5
-
-
0037947557
-
Adeno-associated viruses undergo substantial evolution in primates during natural infections
-
Gao, G. et al. Adeno-associated viruses undergo substantial evolution in primates during natural infections. Proc. Natl. Acad. Sci. USA 100, 6081-6086 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 6081-6086
-
-
Gao, G.1
-
6
-
-
0034050904
-
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
-
Kay, M.A. et al. Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector. Nat. Genet. 24, 257-261 (2000).
-
(2000)
Nat. Genet.
, vol.24
, pp. 257-261
-
-
Kay, M.A.1
-
7
-
-
0013442744
-
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B
-
Manno, C.S. et al. AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B. Blood 101, 2963-2972 (2003).
-
(2003)
Blood
, vol.101
, pp. 2963-2972
-
-
Manno, C.S.1
-
8
-
-
10744227749
-
Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: A multicenter, double-blind, placebo-controlled trial
-
Moss, R.B. et al. Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial. Chest 125, 509-521 (2004).
-
(2004)
Chest
, vol.125
, pp. 509-521
-
-
Moss, R.B.1
-
9
-
-
0024311525
-
Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression
-
Samulski, R.J., Chang, L.S. & Shenk, T. Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J. Virol. 63, 3822-3828 (1989).
-
(1989)
J. Virol.
, vol.63
, pp. 3822-3828
-
-
Samulski, R.J.1
Chang, L.S.2
Shenk, T.3
-
10
-
-
0029257496
-
The cryptic life style of adeno-associated virus
-
Berns, K.I. & Linden, R.M. The cryptic life style of adeno-associated virus. Bioessays 17, 237-245 (1995).
-
(1995)
Bioessays
, vol.17
, pp. 237-245
-
-
Berns, K.I.1
Linden, R.M.2
-
11
-
-
0029843596
-
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector
-
Xiao, X., Li, J. & Samulski, R.J. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. J. Virol. 70, 8098-8108 (1996).
-
(1996)
J. Virol.
, vol.70
, pp. 8098-8108
-
-
Xiao, X.1
Li, J.2
Samulski, R.J.3
-
12
-
-
0033960160
-
Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes
-
Halbert, C.L., Rutledge, E.A., Allen, J.M., Russell, D.W. & Miller, A.D. Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes. J. Virol. 74, 1524-1532 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 1524-1532
-
-
Halbert, C.L.1
Rutledge, E.A.2
Allen, J.M.3
Russell, D.W.4
Miller, A.D.5
-
13
-
-
0031019819
-
Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors
-
Koeberl, D.D., Alexander, I.E., Halbert, C.L., Russell, D.W. & Miller, A.D. Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors. Proc. Natl. Acad. Sci. USA 94, 1426-1431 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1426-1431
-
-
Koeberl, D.D.1
Alexander, I.E.2
Halbert, C.L.3
Russell, D.W.4
Miller, A.D.5
-
14
-
-
0030997346
-
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors
-
Snyder, R.O. et al. Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors. Nat. Genet. 16, 270-276 (1997).
-
(1997)
Nat. Genet.
, vol.16
, pp. 270-276
-
-
Snyder, R.O.1
-
15
-
-
0030003480
-
Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector
-
McCown, T.J., Xiao, X., Li, J., Breese, G.R. & Samulski, R.J. Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Res. 713, 99-107 (1996).
-
(1996)
Brain Res.
, vol.713
, pp. 99-107
-
-
McCown, T.J.1
Xiao, X.2
Li, J.3
Breese, G.R.4
Samulski, R.J.5
-
16
-
-
0037218819
-
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
-
Lai, K., Kaspar, B.K., Gage, F.H. & Schaffer, D.V. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat. Neurosci. 6, 21-27 (2003).
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 21-27
-
-
Lai, K.1
Kaspar, B.K.2
Gage, F.H.3
Schaffer, D.V.4
-
17
-
-
0345411588
-
Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV)
-
Erles, K., Sebokova, P. & Schlehofer, J.R. Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV). J. Med. Virol. 59, 406-411 (1999).
-
(1999)
J. Med. Virol.
, vol.59
, pp. 406-411
-
-
Erles, K.1
Sebokova, P.2
Schlehofer, J.R.3
-
18
-
-
0033920298
-
Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: Implications for gene therapy and virus structure
-
Moskalenko, M. et al. Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structure. J. Virol. 74, 1761-1766 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 1761-1766
-
-
Moskalenko, M.1
-
19
-
-
0033808531
-
Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: Epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection
-
Wobus, C.E. et al. Monoclonal antibodies against the adeno-associated virus type 2 (AAV-2) capsid: epitope mapping and identification of capsid domains involved in AAV-2-cell interaction and neutralization of AAV-2 infection. J. Virol. 74, 9281-9293 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 9281-9293
-
-
Wobus, C.E.1
-
20
-
-
0038805301
-
Immune responses to adeno-associated virus and its recombinant vectors
-
Sun, J.Y., Anand-Jawa, V., Chatterjee, S. & Wong, K.K. Immune responses to adeno-associated virus and its recombinant vectors. Gene Ther. 10, 964-976 (2003).
-
(2003)
Gene Ther.
, vol.10
, pp. 964-976
-
-
Sun, J.Y.1
Anand-Jawa, V.2
Chatterjee, S.3
Wong, K.K.4
-
21
-
-
2642537522
-
Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAVS-mediated, gene transfer in the brain
-
Peden, C.S., Burger, C., Muzyczka, N. & Mandel, R.J. Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAVS-mediated, gene transfer in the brain. J. Virol. 78, 6344-6359 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 6344-6359
-
-
Peden, C.S.1
Burger, C.2
Muzyczka, N.3
Mandel, R.J.4
-
22
-
-
0035800208
-
Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain
-
Nguyen, J.B., Sanchez-Pernaute, R., Cunningham, J. & Bankiewicz, K.S. Convection-enhanced delivery of AAV-2 combined with heparin increases TK gene transfer in the rat brain. Neuroreport 12, 1961-1964 (2001).
-
(2001)
Neuroreport
, vol.12
, pp. 1961-1964
-
-
Nguyen, J.B.1
Sanchez-Pernaute, R.2
Cunningham, J.3
Bankiewicz, K.S.4
-
23
-
-
0037259517
-
Infection efficiency of human and mouse embryonic stem cells using adenoviral and adeno-associated viral vectors
-
Smith-Arica, J.R. et al. Infection efficiency of human and mouse embryonic stem cells using adenoviral and adeno-associated viral vectors. Cloning Stem Cells 5, 51-62 (2003).
-
(2003)
Cloning Stem Cells
, vol.5
, pp. 51-62
-
-
Smith-Arica, J.R.1
-
24
-
-
0036157645
-
Viral-mediated gene transfer to mouse primary neural progenitor cells
-
Hughes, S.M., Moussavi-Harami, F., Sauter, S.L. & Davidson, B.L. Viral-mediated gene transfer to mouse primary neural progenitor cells. Mol. Ther. 5, 16-24 (2002).
-
(2002)
Mol. Ther.
, vol.5
, pp. 16-24
-
-
Hughes, S.M.1
Moussavi-Harami, F.2
Sauter, S.L.3
Davidson, B.L.4
-
25
-
-
0029849257
-
Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
-
Dong, J.Y., Fan, P.D. & Frizzell, R.A. Quantitative analysis of the packaging capacity of recombinant adeno-associated virus. Hum. Gene Ther. 7, 2101-2112 (1996).
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 2101-2112
-
-
Dong, J.Y.1
Fan, P.D.2
Frizzell, R.A.3
-
26
-
-
0021257303
-
Genetics of adeno-associated virus: Isolation and preliminary characterization of adeno-associated virus type 2 mutants
-
Hermonat, P.L., Labow, M.A., Wright, R., Berns, K.I. & Muzyczka, N. Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. J. Virol. 51, 329-339 (1984).
-
(1984)
J. Virol.
, vol.51
, pp. 329-339
-
-
Hermonat, P.L.1
Labow, M.A.2
Wright, R.3
Berns, K.I.4
Muzyczka, N.5
-
27
-
-
0033590138
-
Insertional mutagenesis of AAV2 capsid and the production of recombinant virus
-
Rabinowitz, J.E., Xiao, W. & Samulski, R.J. Insertional mutagenesis of AAV2 capsid and the production of recombinant virus. Virology 265, 274-285 (1999).
-
(1999)
Virology
, vol.265
, pp. 274-285
-
-
Rabinowitz, J.E.1
Xiao, W.2
Samulski, R.J.3
-
28
-
-
0032870158
-
Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2
-
published erratum appears in Nat. Med. 1999 Dec;5(12):1438
-
Girod, A. et al. Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2. Nat Med. [published erratum appears in Nat. Med. 1999 Dec;5(12):1438] 5, 1052-1056 (1999).
-
(1999)
Nat Med.
, vol.5
, pp. 1052-1056
-
-
Girod, A.1
-
29
-
-
0034814413
-
Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell-surface receptors
-
Shi, W., Arnold, G.S. & Bartlett, J.S. Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell-surface receptors. Hum. Gene Ther. 12, 1697-1711 (2001).
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 1697-1711
-
-
Shi, W.1
Arnold, G.S.2
Bartlett, J.S.3
-
30
-
-
0042360384
-
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors
-
Müller, O.J. et al. Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors. Nat. Biotechnol. 21, 1040-1046 (2003).
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1040-1046
-
-
Müller, O.J.1
-
31
-
-
0042031468
-
In vitro selection of viral vectors with modified tropism: The adeno-associated virus display
-
Perabo, L. et al. In vitro selection of viral vectors with modified tropism: the adeno-associated virus display. Mol. Ther. 8, 151-157 (2003).
-
(2003)
Mol. Ther.
, vol.8
, pp. 151-157
-
-
Perabo, L.1
-
32
-
-
0038618725
-
Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding
-
Opie, S.R., Warrington, Jr., K.H., Jr., Agbandje-McKenna, M, Zolotukhin, S. & Muzyczka, N. Identification of amino acid residues in the capsid proteins of adeno-associated virus type 2 that contribute to heparan sulfate proteoglycan binding. J. Virol. 77, 6995-7006 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 6995-7006
-
-
Opie, S.R.1
Warrington Jr., K.H.2
Agbandje-McKenna Jr., M.3
Zolotukhin, S.4
Muzyczka, N.5
-
33
-
-
1842562409
-
Structure of adeno-associated virus serotype 5
-
Walters, R.W. et al. Structure of adeno-associated virus serotype 5. J. Virol. 78, 3361-3371 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 3361-3371
-
-
Walters, R.W.1
-
34
-
-
0036678455
-
The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy
-
Xie, Q. et al. The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy. Proc. Natl. Acad. Sci. USA 99, 10405-10410 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10405-10410
-
-
Xie, Q.1
-
35
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer, W.P. Rapid evolution of a protein in vitro by DNA shuffling. Nature 370, 389-391 (1994).
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.1
-
36
-
-
0034059496
-
Inverting enantioselectivity by directed evolution of hydantoinase for improved production of I-methionine
-
May, O., Nguyen, P.T. & Arnold, F.H. Inverting enantioselectivity by directed evolution of hydantoinase for improved production of I-methionine. Nat. Biotechnol. 18, 317-320 (2000).
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 317-320
-
-
May, O.1
Nguyen, P.T.2
Arnold, F.H.3
-
37
-
-
0030994634
-
Yeast surface display for screening combinatorial polypeptide libraries
-
Boder, E.T. & Wittrup, K.D. Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotechnol. 15, 553-557 (1997).
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 553-557
-
-
Boder, E.T.1
Wittrup, K.D.2
-
38
-
-
0034049316
-
Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies
-
Daugherty, P.S., Chen, G., Iverson, B.L. & Georgiou, G. Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodies. Proc. Natl. Acad. Sci. USA 97, 2029-2034 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2029-2034
-
-
Daugherty, P.S.1
Chen, G.2
Iverson, B.L.3
Georgiou, G.4
-
39
-
-
0034426015
-
Molecular breeding of viruses
-
Soong, N.W. et al. Molecular breeding of viruses. Nat. Genet. 25, 436-439 (2000).
-
(2000)
Nat. Genet.
, vol.25
, pp. 436-439
-
-
Soong, N.W.1
-
40
-
-
0031909113
-
Molecular evolution by staggered extension process (StEP) in vitro recombination
-
Zhao, H., Giver, L., Shao, Z., Affholter, J.A. & Arnold, F.H. Molecular evolution by staggered extension process (StEP) in vitro recombination. Nat. Biotechnol. 16, 258-261 (1998).
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 258-261
-
-
Zhao, H.1
Giver, L.2
Shao, Z.3
Affholter, J.A.4
Arnold, F.H.5
-
41
-
-
0033022953
-
Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield
-
Zolotukhin, S. et al. Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield. Gene Ther. 6, 973-985 (1999).
-
(1999)
Gene Ther.
, vol.6
, pp. 973-985
-
-
Zolotukhin, S.1
-
42
-
-
0036140216
-
Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity
-
Rabinowitz, J.E. et al. Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity. J. Virol. 76, 791-801 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 791-801
-
-
Rabinowitz, J.E.1
-
43
-
-
0031906147
-
Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
-
Summerford, C. & Samulski, R.J. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J. Virol. 72, 1438-1445 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 1438-1445
-
-
Summerford, C.1
Samulski, R.J.2
-
44
-
-
0346147026
-
Genetic modification of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizating effects of human serum antibodies
-
Huttner, N.A. et al. Genetic modification of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizating effects of human serum antibodies. Gene Ther. 10, 2139-2147 (2003).
-
(2003)
Gene Ther.
, vol.10
, pp. 2139-2147
-
-
Huttner, N.A.1
-
45
-
-
2642512201
-
Clades of Adeno-associated viruses are widely disseminated in human tissues
-
Gao, G. et al. Clades of Adeno-associated viruses are widely disseminated in human tissues. J. Virol. 78, 6381-6388 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 6381-6388
-
-
Gao, G.1
-
46
-
-
0034970430
-
-
(ed. Burton, D.R.) Springer-Verlag, Berlin
-
Hewat, E. & Blaas, D. in Antibodies in Viral Infections, vol. 260 (ed. Burton, D.R.) 29-44, (Springer-Verlag, Berlin, 2001).
-
(2001)
Antibodies in Viral Infections
, vol.260
, pp. 29-44
-
-
Hewat, E.1
Blaas, D.2
-
47
-
-
0033987571
-
Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts
-
Hansen, J., Qing, K., Kwon, H.J., Mah, C. & Srivastava, A. Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts. J. Virol. 74, 992-996 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 992-996
-
-
Hansen, J.1
Qing, K.2
Kwon, H.J.3
Mah, C.4
Srivastava, A.5
-
48
-
-
0035827546
-
Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer
-
Walters, R.W. et al. Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer. J. Biol. Chem. 276, 20610-20616 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20610-20616
-
-
Walters, R.W.1
-
49
-
-
0035972806
-
Transfer of high copy number plasmid into mammalian cells by calcium phosphate transfection
-
Batard, P., Jordan, M. & Wurm, F. Transfer of high copy number plasmid into mammalian cells by calcium phosphate transfection. Gene 270, 61-68 (2001).
-
(2001)
Gene
, vol.270
, pp. 61-68
-
-
Batard, P.1
Jordan, M.2
Wurm, F.3
-
50
-
-
0141454787
-
Identification of a heparin-binding motif on adeno-associated virus type 2 capsids
-
Kern, A. et al. Identification of a heparin-binding motif on adeno-associated virus type 2 capsids. J. Virol. 77, 11072-11081 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 11072-11081
-
-
Kern, A.1
|