Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques

Molecular Therapy

Volumn 8, Issue 6, 2003, Pages 918-926

  Fischer, Anne C ^a   Beck, Suzanne E ^b   Smith, Carolina I ^a   Laube, Beth L ^a   Askin, Frederic B ^a   Guggino, Sandra E ^a   Adams, Robert J ^a   Flotte, Terence B ^c   Guggino, William B ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

AAV; Aerosol; CFTR; Cystic fibrosis; Gene therapy; GFP; Microspraying

Indexed keywords

ANTIBODY; GREEN FLUORESCENT PROTEIN; PARVOVIRUS VECTOR; TRANSMEMBRANE CONDUCTANCE REGULATOR;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG TARGETING; GENE EXPRESSION; GENE LOCATION; GENE THERAPY; IMMUNOCOMPETENCE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; MACACA; NONHUMAN; PNEUMONIA; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; SINGLE DRUG DOSE; TRANSGENE; VIRUS RECOMBINANT;

ANIMALIA; MACACA; MACACA MULATTA; MAMMALIA; PARVOVIRUS; PRIMATES;

EID: 0346656769     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2003.08.015     Document Type: Article

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