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Volumn 50, Issue 1, 2011, Pages 121-144

ABC transporters involved in drug resistance in human parasites

Author keywords

[No Author keywords available]

Indexed keywords

APICOMPLEXA; ARCHAEA; ARCHEZOA; EUKARYOTA; KINETOPLASTIDA; TRYPANOSOMATIDAE; VERMES;

EID: 84856275069     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSE0500121     Document Type: Article
Times cited : (28)

References (122)
  • 1
    • 84879234385 scopus 로고    scopus 로고
    • BIO Ventures for Global Health Primer BVGH, Washington, DC
    • BIO Ventures for Global Health Primer (2007) BVGH Global Health Primer, BVGH, Washington, DC
    • (2007) BVGH Global Health Primer
  • 2
    • 57649122948 scopus 로고    scopus 로고
    • World Health Organization World Health Organization, Geneva
    • World Health Organization (2008) World Malaria Report 2008, World Health Organization, Geneva
    • (2008) World Malaria Report 2008
  • 3
    • 1142297431 scopus 로고    scopus 로고
    • Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs
    • Fitch, C.D. (2004) Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs. Life Sci. 74, 1957-1972
    • (2004) Life Sci. , vol.74 , pp. 1957-1972
    • Fitch, C.D.1
  • 5
    • 45249099771 scopus 로고    scopus 로고
    • Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border
    • Wongsrichanalai, C. and Meshnick, S.R. (2008) Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border. Emerg. Infect. Dis. 14, 716-719
    • (2008) Emerg. Infect. Dis. , vol.14 , pp. 716-719
    • Wongsrichanalai, C.1    Meshnick, S.R.2
  • 8
    • 0024338609 scopus 로고
    • Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
    • Foote, S.J., Thompson, J.K., Cowman, A.F. and Kemp, D.J. (1989) Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 57, 921-930
    • (1989) Cell , vol.57 , pp. 921-930
    • Foote, S.J.1    Thompson, J.K.2    Cowman, A.F.3    Kemp, D.J.4
  • 9
    • 0024356582 scopus 로고
    • Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
    • Wilson, C.M., Serrano, A.E., Wasley, A., Bogenschutz, M.P., Shankar, A.H. and Wirth, D.F. (1989) Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 244, 1184-1186
    • (1989) Science , vol.244 , pp. 1184-1186
    • Wilson, C.M.1    Serrano, A.E.2    Wasley, A.3    Bogenschutz, M.P.4    Shankar, A.H.5    Wirth, D.F.6
  • 10
    • 0023137728 scopus 로고
    • Reversal of chloroquine resistance in Plasmodium falciparum by verapamil
    • Martin, S.K., Oduola, A.M. and Milhous, W.K. (1987) Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. Science 235, 899-901
    • (1987) Science , vol.235 , pp. 899-901
    • Martin, S.K.1    Oduola, A.M.2    Milhous, W.K.3
  • 12
    • 0026645269 scopus 로고
    • Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum
    • Barnes, D.A., Foote, S.J., Galatis, D., Kemp, D.J. and Cowman, A.F. (1992) Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. EMBO J. 11, 3067-3075
    • (1992) EMBO J. , vol.11 , pp. 3067-3075
    • Barnes, D.A.1    Foote, S.J.2    Galatis, D.3    Kemp, D.J.4    Cowman, A.F.5
  • 14
    • 77954029768 scopus 로고    scopus 로고
    • Transporters as mediators of drug resistance in Plasmodium falciparum
    • Sanchez, C.P., Dave, A., Stein, W.D. and Lanzer, M. (2010) Transporters as mediators of drug resistance in Plasmodium falciparum. Int. J. Parasitol. 40, 1109-1118
    • (2010) Int. J. Parasitol. , vol.40 , pp. 1109-1118
    • Sanchez, C.P.1    Dave, A.2    Stein, W.D.3    Lanzer, M.4
  • 15
    • 70349524663 scopus 로고    scopus 로고
    • Chloroquine transport via the malaria parasite's chloroquine resistance transporter
    • Martin, R.E., Marchetti, R.V., Cowan, A.I., Howitt, S.M., Broer, S. and Kirk, K. (2009) Chloroquine transport via the malaria parasite's chloroquine resistance transporter. Science 325, 1680-1682
    • (2009) Science , vol.325 , pp. 1680-1682
    • Martin, R.E.1    Marchetti, R.V.2    Cowan, A.I.3    Howitt, S.M.4    Broer, S.5    Kirk, K.6
  • 16
    • 33746676404 scopus 로고    scopus 로고
    • Antimalarial drugs: Recent advances in molecular determinants of resistance and their clinical significance
    • Woodrow, C.J. and Krishna, S. (2006) Antimalarial drugs: recent advances in molecular determinants of resistance and their clinical significance. Cell. Mol. Life Sci. 63, 1586-1596
    • (2006) Cell. Mol. Life Sci. , vol.63 , pp. 1586-1596
    • Woodrow, C.J.1    Krishna, S.2
  • 19
    • 33746302565 scopus 로고    scopus 로고
    • Decreasing pfmdr1 copy number in Plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin
    • Sidhu, A.B., Uhlemann, A.C., Valderramos, S.G., Valderramos, J.C., Krishna, S. and Fidock, D.A. (2006) Decreasing pfmdr1 copy number in Plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin. J. Infect. Dis. 194, 528-535
    • (2006) J. Infect. Dis. , vol.194 , pp. 528-535
    • Sidhu, A.B.1    Uhlemann, A.C.2    Valderramos, S.G.3    Valderramos, J.C.4    Krishna, S.5    Fidock, D.A.6
  • 20
    • 33747880765 scopus 로고    scopus 로고
    • Surveillance of the efficacy of artesunate and mefloquine combination for the treatment of uncomplicated falciparum malaria in Cambodia
    • Denis, M.B., Tsuyuoka, R., Poravuth, Y., Narann, T.S., Seila, S., Lim, C., Incardona, S., Lim, P., Sem, R., Socheat, D. et al. (2006) Surveillance of the efficacy of artesunate and mefloquine combination for the treatment of uncomplicated falciparum malaria in Cambodia. Trop. Med. Int. Health 11, 1360-1366
    • (2006) Trop. Med. Int. Health , vol.11 , pp. 1360-1366
    • Denis, M.B.1    Tsuyuoka, R.2    Poravuth, Y.3    Narann, T.S.4    Seila, S.5    Lim, C.6    Incardona, S.7    Lim, P.8    Sem, R.9    Socheat, D.10
  • 21
    • 10044284223 scopus 로고    scopus 로고
    • In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002
    • Lim, P., Chim, P., Sem, R., Nemh, S., Poravuth, Y., Lim, C., Seila, S., Tsuyuoka, R., Denis, M.B., Socheat, D. et al. (2005) In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002. Acta Trop. 93, 31-40
    • (2005) Acta Trop. , vol.93 , pp. 31-40
    • Lim, P.1    Chim, P.2    Sem, R.3    Nemh, S.4    Poravuth, Y.5    Lim, C.6    Seila, S.7    Tsuyuoka, R.8    Denis, M.B.9    Socheat, D.10
  • 22
    • 0025269612 scopus 로고
    • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
    • Foote, S.J., Kyle, D.E., Martin, R.K., Oduola, A.M., Forsyth, K., Kemp, D.J. and Cowman, A.F. (1990) Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345, 255-258
    • (1990) Nature , vol.345 , pp. 255-258
    • Foote, S.J.1    Kyle, D.E.2    Martin, R.K.3    Oduola, A.M.4    Forsyth, K.5    Kemp, D.J.6    Cowman, A.F.7
  • 23
    • 23744435838 scopus 로고    scopus 로고
    • Pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
    • Sidhu, A.B., Valderramos, S.G. and Fidock, D.A. (2005) pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Mol. Microbiol. 57, 913-926
    • (2005) Mol. Microbiol. , vol.57 , pp. 913-926
    • Sidhu, A.B.1    Valderramos, S.G.2    Fidock, D.A.3
  • 24
    • 0034827271 scopus 로고    scopus 로고
    • Plasmodium falciparum: Linkage disequilibrium between loci in chromosomes 7 and 5 and chloroquine selective pressure in Northern Nigeria
    • Adagu, I.S. and Warhurst, D.C. (2001) Plasmodium falciparum: linkage disequilibrium between loci in chromosomes 7 and 5 and chloroquine selective pressure in Northern Nigeria. Parasitology 123, 219-224
    • (2001) Parasitology , vol.123 , pp. 219-224
    • Adagu, I.S.1    Warhurst, D.C.2
  • 25
    • 0035873715 scopus 로고    scopus 로고
    • High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1
    • Babiker, H.A., Pringle, S.J., Abdel-Muhsin, A., Mackinnon, M., Hunt, P. and Walliker, D. (2001) High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1. J. Infect. Dis. 183, 1535-1538
    • (2001) J. Infect. Dis. , vol.183 , pp. 1535-1538
    • Babiker, H.A.1    Pringle, S.J.2    Abdel-Muhsin, A.3    Mackinnon, M.4    Hunt, P.5    Walliker, D.6
  • 27
    • 0034112601 scopus 로고    scopus 로고
    • Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum
    • Duraisingh, M.T., Roper, C., Walliker, D. and Warhurst, D.C. (2000) Increased sensitivity to the antimalarials mefloquine and artemisinin is conferred by mutations in the pfmdr1 gene of Plasmodium falciparum. Mol. Microbiol. 36, 955-961
    • (2000) Mol. Microbiol. , vol.36 , pp. 955-961
    • Duraisingh, M.T.1    Roper, C.2    Walliker, D.3    Warhurst, D.C.4
  • 28
    • 0034732666 scopus 로고    scopus 로고
    • The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin
    • Duraisingh, M.T., Jones, P., Sambou, I., von Seidlein, L., Pinder, M. and Warhurst, D.C. (2000) The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin. Mol. Biochem. Parasitol. 108, 13-23
    • (2000) Mol. Biochem. Parasitol. , vol.108 , pp. 13-23
    • Duraisingh, M.T.1    Jones, P.2    Sambou, I.3    Von Seidlein, L.4    Pinder, M.5    Warhurst, D.C.6
  • 30
    • 33646450674 scopus 로고    scopus 로고
    • Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic
    • Dokomajilar, C., Nsobya, S.L., Greenhouse, B., Rosenthal, P.J. and Dorsey, G. (2006) Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic. Antimicrob. Agents Chemother. 50, 1893-1895
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1893-1895
    • Dokomajilar, C.1    Nsobya, S.L.2    Greenhouse, B.3    Rosenthal, P.J.4    Dorsey, G.5
  • 31
    • 62949106152 scopus 로고    scopus 로고
    • Selection of Plasmodium falciparum multidrug resistance gene 1 alleles in asexual stages and gametocytes by artemether-lumefantrine in Nigerian children with uncomplicated falciparum malaria
    • Happi, C.T., Gbotosho, G.O., Folarin, O.A., Sowunmi, A., Hudson, T., O'Neil, M., Milhous, W., Wirth, D.F. and Oduola, A.M. (2009) Selection of Plasmodium falciparum multidrug resistance gene 1 alleles in asexual stages and gametocytes by artemether-lumefantrine in Nigerian children with uncomplicated falciparum malaria. Antimicrob. Agents Chemother. 53, 888-895
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 888-895
    • Happi, C.T.1    Gbotosho, G.O.2    Folarin, O.A.3    Sowunmi, A.4    Hudson, T.5    O'Neil, M.6    Milhous, W.7    Wirth, D.F.8    Oduola, A.M.9
  • 32
    • 33847655633 scopus 로고    scopus 로고
    • Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria
    • Humphreys, G.S., Merinopoulos, I., Ahmed, J., Whitty, C.J., Mutabingwa, T.K., Sutherland, C.J. and Hallett, R.L. (2007) Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria. Antimicrob. Agents Chemother. 51, 991-997
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 991-997
    • Humphreys, G.S.1    Merinopoulos, I.2    Ahmed, J.3    Whitty, C.J.4    Mutabingwa, T.K.5    Sutherland, C.J.6    Hallett, R.L.7
  • 33
    • 71249142664 scopus 로고    scopus 로고
    • In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1
    • Mwai, L., Kiara, S.M., Abdirahman, A., Pole, L., Rippert, A., Diriye, A., Bull, P., Marsh, K., Borrmann, S. and Nzila, A. (2009) In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1. Antimicrob. Agents Chemother. 53, 5069-5073
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 5069-5073
    • Mwai, L.1    Kiara, S.M.2    Abdirahman, A.3    Pole, L.4    Rippert, A.5    Diriye, A.6    Bull, P.7    Marsh, K.8    Borrmann, S.9    Nzila, A.10
  • 34
    • 14844327986 scopus 로고    scopus 로고
    • In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem)
    • Sisowath, C., Stromberg, J., Martensson, A., Msellem, M., Obondo, C., Bjorkman, A. and Gil, J.P. (2005) In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem). J. Infect. Dis. 191, 1014-1017
    • (2005) J. Infect. Dis. , vol.191 , pp. 1014-1017
    • Sisowath, C.1    Stromberg, J.2    Martensson, A.3    Msellem, M.4    Obondo, C.5    Bjorkman, A.6    Gil, J.P.7
  • 36
    • 54249123267 scopus 로고    scopus 로고
    • Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum
    • Sanchez, C.P., Rotmann, A., Stein, W.D. and Lanzer, M. (2008) Polymorphisms within PfMDR1 alter the substrate specificity for anti-malarial drugs in Plasmodium falciparum. Mol. Microbiol. 70, 786-798
    • (2008) Mol. Microbiol. , vol.70 , pp. 786-798
    • Sanchez, C.P.1    Rotmann, A.2    Stein, W.D.3    Lanzer, M.4
  • 38
    • 19544366088 scopus 로고    scopus 로고
    • Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance?
    • Anderson, T.J., Nair, S., Qin, H., Singlam, S., Brockman, A., Paiphun, L. and Nosten, F. (2005) Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance? Antimicrob. Agents Chemother. 49, 2180-2188
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 2180-2188
    • Anderson, T.J.1    Nair, S.2    Qin, H.3    Singlam, S.4    Brockman, A.5    Paiphun, L.6    Nosten, F.7
  • 39
    • 33646355728 scopus 로고    scopus 로고
    • Lack of association between putative transporter gene polymorphisms in Plasmodium falciparum and chloroquine resistance in imported malaria isolates from Africa
    • Cojean, S., Noël, A., Garnier, D., Hubert, V., Le Bras, J. and Durand, R. (2006) Lack of association between putative transporter gene polymorphisms in Plasmodium falciparum and chloroquine resistance in imported malaria isolates from Africa. Malar. J. 5, 24
    • (2006) Malar. J. , vol.5 , pp. 24
    • Cojean, S.1    Noël, A.2    Garnier, D.3    Hubert, V.4    Le Bras, J.5    Durand, R.6
  • 40
    • 65549119262 scopus 로고    scopus 로고
    • Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PfMRP) alters its fitness and transport of antimalarial drugs and glutathione
    • Raj, D.K., Mu, J., Jiang, H., Kabat, J., Singh, S., Sullivan, M., Fay, M.P., McCutchan, T.F. and Su, X.Z. (2009) Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PfMRP) alters its fitness and transport of antimalarial drugs and glutathione. J. Biol. Chem. 284, 7687-7696
    • (2009) J. Biol. Chem. , vol.284 , pp. 7687-7696
    • Raj, D.K.1    Mu, J.2    Jiang, H.3    Kabat, J.4    Singh, S.5    Sullivan, M.6    Fay, M.P.7    McCutchan, T.F.8    Su, X.Z.9
  • 41
    • 70349257342 scopus 로고    scopus 로고
    • Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane
    • Kavishe, R.A., van den Heuvel, J.M., van de Vegte-Bolmer, M., Luty, A.J., Russel, F.G. and Koenderink, J.B. (2009) Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane. Malar. J. 8, 205
    • (2009) Malar. J. , vol.8 , pp. 205
    • Kavishe, R.A.1    Van Den Heuvel, J.M.2    Van De Vegte-Bolmer, M.3    Luty, A.J.4    Russel, F.G.5    Koenderink, J.B.6
  • 42
    • 67049173048 scopus 로고    scopus 로고
    • Polymorphism in PfMRP1 (Plasmodium falciparum multidrug resistance protein 1) amino acid 1466 associated with resistance to sulfadoxine- pyrimethamine treatment
    • Dahlstrom, S., Veiga, M.I., Martensson, A., Bjorkman, A. and Gil, J.P. (2009) Polymorphism in PfMRP1 (Plasmodium falciparum multidrug resistance protein 1) amino acid 1466 associated with resistance to sulfadoxine- pyrimethamine treatment. Antimicrob. Agents Chemother. 53, 2553-2556
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 2553-2556
    • Dahlstrom, S.1    Veiga, M.I.2    Martensson, A.3    Bjorkman, A.4    Gil, J.P.5
  • 43
    • 77649185865 scopus 로고    scopus 로고
    • Early transcriptional response to chloroquine of the Plasmodium falciparum antioxidant defence in sensitive and resistant clones
    • Nogueira, F., Diez, A., Radfar, A., Pérez-Benavente, S., Rosario, V.E., Puyet, A. and Bautista, J.M. (2010) Early transcriptional response to chloroquine of the Plasmodium falciparum antioxidant defence in sensitive and resistant clones. Acta Trop. 114, 109-115
    • (2010) Acta Trop. , vol.114 , pp. 109-115
    • Nogueira, F.1    Diez, A.2    Radfar, A.3    Pérez-Benavente, S.4    Rosario, V.E.5    Puyet, A.6    Bautista, J.M.7
  • 45
    • 0027473406 scopus 로고
    • Transcripts of the multidrug resistance genes in chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum
    • Ekong, R.M., Robson, K.J., Baker, D.A. and Warhurst, D.C. (1993) Transcripts of the multidrug resistance genes in chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. Parasitology 106, 107-115
    • (1993) Parasitology , vol.106 , pp. 107-115
    • Ekong, R.M.1    Robson, K.J.2    Baker, D.A.3    Warhurst, D.C.4
  • 46
    • 0028169583 scopus 로고
    • Plasmodium falciparum: The pfmdr2 protein is not overex-pressed in chloroquine-resistant isolates of the malaria parasite
    • Rubio, J.P. and Cowman, A.F. (1994) Plasmodium falciparum: the pfmdr2 protein is not overex-pressed in chloroquine-resistant isolates of the malaria parasite. Exp. Parasitol. 79, 137-147
    • (1994) Exp. Parasitol. , vol.79 , pp. 137-147
    • Rubio, J.P.1    Cowman, A.F.2
  • 48
    • 0036462586 scopus 로고    scopus 로고
    • Cryptosporidiosis and the challenges of chemotherapy
    • Mead, J.R. (2002) Cryptosporidiosis and the challenges of chemotherapy. Drug Resist. Updat. 5, 47-57
    • (2002) Drug Resist. Updat. , vol.5 , pp. 47-57
    • Mead, J.R.1
  • 49
    • 2542478051 scopus 로고    scopus 로고
    • Cryptosporidium parvum: Effect of multi-drug reversing agents on the expression and function of ATP-binding cassette transporters
    • Bonafonte, M.T., Romagnoli, P.A., McNair, N., Shaw, A.P., Scanlon, M., Leitch, G.J. and Mead, J.R. (2004) Cryptosporidium parvum: effect of multi-drug reversing agents on the expression and function of ATP-binding cassette transporters. Exp. Parasitol. 106, 126-134
    • (2004) Exp. Parasitol. , vol.106 , pp. 126-134
    • Bonafonte, M.T.1    Romagnoli, P.A.2    McNair, N.3    Shaw, A.P.4    Scanlon, M.5    Leitch, G.J.6    Mead, J.R.7
  • 51
    • 0033545854 scopus 로고    scopus 로고
    • CpABC, a Cryptosporidium parvum ATP-binding cassette protein at the host-parasite boundary in intracellular stages
    • Perkins, M.E., Riojas, Y.A., Wu, T.W. and Le Blancq, S.M. (1999) CpABC, a Cryptosporidium parvum ATP-binding cassette protein at the host-parasite boundary in intracellular stages. Proc. Natl. Acad. Sci. U.S.A. 96, 5734-5739
    • (1999) Proc. Natl. Acad. Sci. U.S.A , vol.96 , pp. 5734-5739
    • Perkins, M.E.1    Riojas, Y.A.2    Wu, T.W.3    Le Blancq, S.M.4
  • 52
    • 34948859491 scopus 로고    scopus 로고
    • Modulation of gene expression of three Cryptosporidium parvum ATP-binding cassette transporters in response to drug treatment
    • Benitez, A.J., McNair, N. and Mead, J. (2007) Modulation of gene expression of three Cryptosporidium parvum ATP-binding cassette transporters in response to drug treatment. Parasitol. Res. 101, 1611-1616
    • (2007) Parasitol. Res. , vol.101 , pp. 1611-1616
    • Benitez, A.J.1    McNair, N.2    Mead, J.3
  • 53
    • 62249095482 scopus 로고    scopus 로고
    • Functional characterization of the nucleotide binding domain of the Cryptosporidium parvum CpABC4 transporter: An iron-sulfur cluster transporter homolog
    • Benitez, A.J., Arrowood, M.J. and Mead, J.R. (2009) Functional characterization of the nucleotide binding domain of the Cryptosporidium parvum CpABC4 transporter: an iron-sulfur cluster transporter homolog. Mol. Biochem. Parasitol. 165, 103-110
    • (2009) Mol. Biochem. Parasitol. , vol.165 , pp. 103-110
    • Benitez, A.J.1    Arrowood, M.J.2    Mead, J.R.3
  • 54
    • 0033509735 scopus 로고    scopus 로고
    • Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani
    • Lira, R., Sundar, S., Makharia, A., Kenney, R., Gam, A., Saraiva, E. and Sacks, D. (1999) Evidence that the high incidence of treatment failures in Indian kala-azar is due to the emergence of antimony-resistant strains of Leishmania donovani. J. Infect. Dis. 180, 564-567
    • (1999) J. Infect. Dis. , vol.180 , pp. 564-567
    • Lira, R.1    Sundar, S.2    Makharia, A.3    Kenney, R.4    Gam, A.5    Saraiva, E.6    Sacks, D.7
  • 58
    • 33750384376 scopus 로고    scopus 로고
    • Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites
    • Leprohon, P., Legare, D., Girard, I., Papadopoulou, B. and Ouellette, M. (2006) Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites. Eukaryotic Cell 5, 1713-1725
    • (2006) Eukaryotic Cell , vol.5 , pp. 1713-1725
    • Leprohon, P.1    Legare, D.2    Girard, I.3    Papadopoulou, B.4    Ouellette, M.5
  • 59
    • 15444369622 scopus 로고    scopus 로고
    • The overexpression of an intracellular ABCA-like transporter alters phospholipid trafficking in Leishmania
    • Araujo-Santos, J.M., Parodi-Talice, A., Castanys, S. and Gamarro, F. (2005) The overexpression of an intracellular ABCA-like transporter alters phospholipid trafficking in Leishmania. Biochem. Biophys. Res. Commun. 330, 349-355
    • (2005) Biochem. Biophys. Res. Commun. , vol.330 , pp. 349-355
    • Araujo-Santos, J.M.1    Parodi-Talice, A.2    Castanys, S.3    Gamarro, F.4
  • 60
    • 0038730501 scopus 로고    scopus 로고
    • The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity
    • Parodi-Talice, A., Araujo, J.M., Torres, C., Perez-Victoria, J.M., Gamarro, F. and Castanys, S. (2003) The overexpression of a new ABC transporter in Leishmania is related to phospholipid trafficking and reduced infectivity. Biochim. Biophys. Acta 1612, 195-207
    • (2003) Biochim. Biophys. Acta , vol.1612 , pp. 195-207
    • Parodi-Talice, A.1    Araujo, J.M.2    Torres, C.3    Perez-Victoria, J.M.4    Gamarro, F.5    Castanys, S.6
  • 62
    • 33745190490 scopus 로고    scopus 로고
    • Drug resistance mechanisms in clinical isolates of Leishmania donovani
    • Singh, N. (2006) Drug resistance mechanisms in clinical isolates of Leishmania donovani. Indian J. Med. Res. 123, 411-422
    • (2006) Indian J. Med. Res. , vol.123 , pp. 411-422
    • Singh, N.1
  • 63
    • 0025321675 scopus 로고
    • The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene
    • Ouellette, M., Fase-Fowler, F. and Borst, P. (1990) The amplified H circle of methotrexate-resistant leishmania tarentolae contains a novel P-glycoprotein gene. EMBO J. 9, 1027-1033
    • (1990) EMBO J. , vol.9 , pp. 1027-1033
    • Ouellette, M.1    Fase-Fowler, F.2    Borst, P.3
  • 64
    • 31844455959 scopus 로고    scopus 로고
    • Substrate recognition and transport by multidrug resistance protein 1 (ABCC1)
    • Deeley, R.G. and Cole, S.P. (2006) Substrate recognition and transport by multidrug resistance protein 1 (ABCC1). FEBS Lett. 580, 1103-1111
    • (2006) FEBS Lett. , vol.580 , pp. 1103-1111
    • Deeley, R.G.1    Cole, S.P.2
  • 65
    • 0026793462 scopus 로고
    • Metabolism and functions of trypanothione in the Kinetoplastida
    • Fairlamb, A.H. and Cerami, A. (1992) Metabolism and functions of trypanothione in the Kinetoplastida. Annu. Rev. Microbiol. 46, 695-729
    • (1992) Annu. Rev. Microbiol. , vol.46 , pp. 695-729
    • Fairlamb, A.H.1    Cerami, A.2
  • 66
    • 7944237421 scopus 로고    scopus 로고
    • Leishmaniasis: Drugs in the clinic, resistance and new developments
    • Ouellette, M., Drummelsmith, J. and Papadopoulou, B. (2004) Leishmaniasis: drugs in the clinic, resistance and new developments. Drug Resist. Updat. 7, 257-266
    • (2004) Drug Resist. Updat. , vol.7 , pp. 257-266
    • Ouellette, M.1    Drummelsmith, J.2    Papadopoulou, B.3
  • 67
    • 67049116076 scopus 로고    scopus 로고
    • Intracellular localization of the ABCC proteins of Leishmania and their role in resistance to antimonials
    • Leprohon, P., Legare, D. and Ouellette, M. (2009) Intracellular localization of the ABCC proteins of Leishmania and their role in resistance to antimonials. Antimicrob. Agents Chemother. 53, 2646-2649
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 2646-2649
    • Leprohon, P.1    Legare, D.2    Ouellette, M.3
  • 70
    • 25144440472 scopus 로고    scopus 로고
    • Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania
    • Marquis, N., Gourbal, B., Rosen, B.P., Mukhopadhyay, R. and Ouellette, M. (2005) Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania. Mol. Microbiol. 57, 1690-1699
    • (2005) Mol. Microbiol. , vol.57 , pp. 1690-1699
    • Marquis, N.1    Gourbal, B.2    Rosen, B.P.3    Mukhopadhyay, R.4    Ouellette, M.5
  • 72
    • 0029914454 scopus 로고    scopus 로고
    • An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae
    • Dey, S., Ouellette, M., Lightbody, J., Papadopoulou, B. and Rosen, B.P. (1996) An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae. Proc. Natl. Acad. Sci. U.S.A. 93, 2192-2197
    • (1996) Proc. Natl. Acad. Sci. U.S.A , vol.93 , pp. 2192-2197
    • Dey, S.1    Ouellette, M.2    Lightbody, J.3    Papadopoulou, B.4    Rosen, B.P.5
  • 73
    • 33947528405 scopus 로고    scopus 로고
    • Role of ABC transporter MRPA, γ-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani
    • Mukherjee, A., Padmanabhan, P.K., Singh, S., Roy, G., Girard, I., Chatterjee, M., Ouellette, M. and Madhubala, R. (2007) Role of ABC transporter MRPA, γ-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani. J. Antimicrob. Chemother. 59, 204-211
    • (2007) J. Antimicrob. Chemother. , vol.59 , pp. 204-211
    • Mukherjee, A.1    Padmanabhan, P.K.2    Singh, S.3    Roy, G.4    Girard, I.5    Chatterjee, M.6    Ouellette, M.7    Madhubala, R.8
  • 74
    • 77952997887 scopus 로고    scopus 로고
    • Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites
    • Singh, R., Kumar, D., Duncan, R.C., Nakhasi, H.L. and Salotra, P. (2010) Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites. Int. J. Antimicrob. Agents 36, 50-57
    • (2010) Int. J. Antimicrob. Agents , vol.36 , pp. 50-57
    • Singh, R.1    Kumar, D.2    Duncan, R.C.3    Nakhasi, H.L.4    Salotra, P.5
  • 75
    • 0020605193 scopus 로고
    • Evaluation of diamidine compound (pentamidine isethionate) in the treatment resistant cases of kala-azar occurring in North Bihar, India
    • Jha, T.K. (1983) Evaluation of diamidine compound (pentamidine isethionate) in the treatment resistant cases of kala-azar occurring in North Bihar, India. Trans. R. Soc. Trop. Med. Hyg. 77, 167-170
    • (1983) Trans. R. Soc. Trop. Med. Hyg. , vol.77 , pp. 167-170
    • Jha, T.K.1
  • 76
    • 0036894232 scopus 로고    scopus 로고
    • Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion
    • Basselin, M., Denise, H., Coombs, G.H. and Barrett, M.P. (2002) Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion. Antimicrob. Agents Chemother. 46, 3731-3738
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 3731-3738
    • Basselin, M.1    Denise, H.2    Coombs, G.H.3    Barrett, M.P.4
  • 77
    • 0142106997 scopus 로고    scopus 로고
    • Functional genetic identifcation of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major
    • Coelho, A.C., Beverley, S.M. and Cotrim, P.C. (2003) Functional genetic identifcation of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major. Mol. Biochem. Parasitol. 130, 83-90
    • (2003) Mol. Biochem. Parasitol. , vol.130 , pp. 83-90
    • Coelho, A.C.1    Beverley, S.M.2    Cotrim, P.C.3
  • 78
    • 34547615972 scopus 로고    scopus 로고
    • Role of the ABC transporter PRP1 (ABCC7) in pentamidine resistance in Leishmania amastigotes
    • Coelho, A.C., Messier, N., Ouellette, M. and Cotrim, P.C. (2007) Role of the ABC transporter PRP1 (ABCC7) in pentamidine resistance in Leishmania amastigotes. Antimicrob. Agents Chemother. 51, 3030-3032
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 3030-3032
    • Coelho, A.C.1    Messier, N.2    Ouellette, M.3    Cotrim, P.C.4
  • 79
    • 48649083497 scopus 로고    scopus 로고
    • Characterization of Leishmania (Leishmania) amazonensis promastigotes resistant to pentamidine
    • Coelho, A.C., Gentil, L.G., da Silveira, J.F. and Cotrim, P.C. (2008) Characterization of Leishmania (Leishmania) amazonensis promastigotes resistant to pentamidine. Exp. Parasitol. 120, 98-102
    • (2008) Exp. Parasitol. , vol.120 , pp. 98-102
    • Coelho, A.C.1    Gentil, L.G.2    Da Silveira, J.F.3    Cotrim, P.C.4
  • 80
    • 1642443137 scopus 로고    scopus 로고
    • Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites
    • Dodge, M.A., Waller, R.F., Chow, L.M., Zaman, M.M., Cotton, L.M., McConville, M.J. and Wirth, D.F. (2004) Localization and activity of multidrug resistance protein 1 in the secretory pathway of Leishmania parasites. Mol. Microbiol. 51, 1563-1575
    • (2004) Mol. Microbiol. , vol.51 , pp. 1563-1575
    • Dodge, M.A.1    Waller, R.F.2    Chow, L.M.3    Zaman, M.M.4    Cotton, L.M.5    McConville, M.J.6    Wirth, D.F.7
  • 82
    • 65749103218 scopus 로고    scopus 로고
    • Quinacrine and a novel apigenin dimer can synergistically increase the pentamidine susceptibility of the protozoan parasite Leishmania
    • Wong, I.L., Chan, K.F., Zhao, Y., Chan, T.H. and Chow, L.M. (2009) Quinacrine and a novel apigenin dimer can synergistically increase the pentamidine susceptibility of the protozoan parasite Leishmania. J. Antimicrob. Chemother. 63, 1179-1190
    • (2009) J. Antimicrob. Chemother. , vol.63 , pp. 1179-1190
    • Wong, I.L.1    Chan, K.F.2    Zhao, Y.3    Chan, T.H.4    Chow, L.M.5
  • 84
    • 34249787648 scopus 로고    scopus 로고
    • A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids
    • Castanys-Munoz, E., Alder-Baerens, N., Pomorski, T., Gamarro, F. and Castanys, S. (2007) A novel ATP-binding cassette transporter from Leishmania is involved in transport of phosphatidylcholine analogues and resistance to alkyl-phospholipids. Mol. Microbiol. 64, 1141-1153
    • (2007) Mol. Microbiol. , vol.64 , pp. 1141-1153
    • Castanys-Munoz, E.1    Alder-Baerens, N.2    Pomorski, T.3    Gamarro, F.4    Castanys, S.5
  • 85
    • 54049089634 scopus 로고    scopus 로고
    • Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement
    • Castanys-Munoz, E., Perez-Victoria, J.M., Gamarro, F. and Castanys, S. (2008) Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement. Antimicrob. Agents Chemother. 52, 3573-3579
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 3573-3579
    • Castanys-Munoz, E.1    Perez-Victoria, J.M.2    Gamarro, F.3    Castanys, S.4
  • 86
    • 39049150303 scopus 로고    scopus 로고
    • A novel ATP-binding cassette transporter, ABCG6 is involved in chemoresistance of Leishmania
    • BoseDasgupta, S., Ganguly, A., Roy, A., Mukherjee, T. and Majumder, H.K. (2008) A novel ATP-binding cassette transporter, ABCG6 is involved in chemoresistance of Leishmania. Mol. Biochem. Parasitol. 158, 176-188
    • (2008) Mol. Biochem. Parasitol. , vol.158 , pp. 176-188
    • BoseDasgupta, S.1    Ganguly, A.2    Roy, A.3    Mukherjee, T.4    Majumder, H.K.5
  • 87
    • 1542268311 scopus 로고    scopus 로고
    • Overexpression of LaMDR2, a novel multidrug resistance ATP-binding cassette transporter, causes 5-fluorouracil resistance in Leishmania amazonensis
    • Katakura, K., Fujise, H., Takeda, K., Kaneko, O., Torii, M., Suzuki, M., Chang, K.P. and Hashiguchi, Y. (2004) Overexpression of LaMDR2, a novel multidrug resistance ATP-binding cassette transporter, causes 5-fluorouracil resistance in Leishmania amazonensis. FEBS Lett. 561, 207-212
    • (2004) FEBS Lett. , vol.561 , pp. 207-212
    • Katakura, K.1    Fujise, H.2    Takeda, K.3    Kaneko, O.4    Torii, M.5    Suzuki, M.6    Chang, K.P.7    Hashiguchi, Y.8
  • 90
    • 0034777039 scopus 로고    scopus 로고
    • The phenomenon of treatment failures in human African trypanosomiasis
    • Brun, R., Schumacher, R., Schmid, C., Kunz, C. and Burri, C. (2001) The phenomenon of treatment failures in human African trypanosomiasis. Trop. Med. Int. Health 6, 906-914
    • (2001) Trop. Med. Int. Health , vol.6 , pp. 906-914
    • Brun, R.1    Schumacher, R.2    Schmid, C.3    Kunz, C.4    Burri, C.5
  • 92
    • 0036223214 scopus 로고    scopus 로고
    • Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei
    • Shahi, S.K., Krauth-Siegel, R.L. and Clayton, C.E. (2002) Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei. Mol. Microbiol. 43, 1129-1138
    • (2002) Mol. Microbiol. , vol.43 , pp. 1129-1138
    • Shahi, S.K.1    Krauth-Siegel, R.L.2    Clayton, C.E.3
  • 94
    • 0013848978 scopus 로고
    • Trichomonas vaginalis. V. Further observations on metronidazole (Flagyl) (including infant follow-up)
    • Robinson, S.C. and Mirchandani, G. (1965) Trichomonas vaginalis. V. Further observations on metronidazole (Flagyl) (including infant follow-up). Am. J. Obstet. Gynecol. 93, 502-505
    • (1965) Am. J. Obstet. Gynecol. , vol.93 , pp. 502-505
    • Robinson, S.C.1    Mirchandani, G.2
  • 95
    • 0025090521 scopus 로고
    • Entamoeba histolytica: Physiology of multidrug resistance
    • Ayala, P., Samuelson, J., Wirth, D. and Orozco, E. (1990) Entamoeba histolytica: physiology of multidrug resistance. Exp. Parasitol. 71, 169-175
    • (1990) Exp. Parasitol. , vol.71 , pp. 169-175
    • Ayala, P.1    Samuelson, J.2    Wirth, D.3    Orozco, E.4
  • 96
    • 0026475264 scopus 로고
    • Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers
    • Samuelson, J.C., Burke, A. and Courval, J.M. (1992) Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers. Antimicrob. Agents Chemother. 36, 2392-2397
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 2392-2397
    • Samuelson, J.C.1    Burke, A.2    Courval, J.M.3
  • 97
    • 0028783862 scopus 로고
    • Increase in mRNA of multiple Eh pgp genes encoding P-glycoprotein homologues in emetine-resistant Entamoeba histolytica parasites
    • Descoteaux, S., Ayala, P., Samuelson, J. and Orozco, E. (1995) Increase in mRNA of multiple Eh pgp genes encoding P-glycoprotein homologues in emetine-resistant Entamoeba histolytica parasites. Gene 164, 179-184
    • (1995) Gene , vol.164 , pp. 179-184
    • Descoteaux, S.1    Ayala, P.2    Samuelson, J.3    Orozco, E.4
  • 98
    • 0037500222 scopus 로고    scopus 로고
    • EhPgp5 mRNA stability is a regulatory event in the Entamoeba histolytica multidrug resistance phenotype
    • Lopez-Camarillo, C., Luna-Arias, J.P., Marchat, L.A. and Orozco, E. (2003) EhPgp5 mRNA stability is a regulatory event in the Entamoeba histolytica multidrug resistance phenotype. J. Biol. Chem. 278, 11273-11280
    • (2003) J. Biol. Chem. , vol.278 , pp. 11273-11280
    • Lopez-Camarillo, C.1    Luna-Arias, J.P.2    Marchat, L.A.3    Orozco, E.4
  • 99
    • 0030602249 scopus 로고    scopus 로고
    • Overexpression of P-glycoprotein gene 1 by transfected Entamoeba histolytica confers emetine-resistance
    • Ghosh, S.K., Lohia, A., Kumar, A. and Samuelson, J. (1996) Overexpression of P-glycoprotein gene 1 by transfected Entamoeba histolytica confers emetine-resistance. Mol. Biochem. Parasitol. 82, 257-260
    • (1996) Mol. Biochem. Parasitol. , vol.82 , pp. 257-260
    • Ghosh, S.K.1    Lohia, A.2    Kumar, A.3    Samuelson, J.4
  • 100
    • 0036927111 scopus 로고    scopus 로고
    • Cellular location and function of the P-glycoproteins (EhPgps) in Entamoeba histolytica multidrug-resistant trophozoites
    • Banuelos, C., Orozco, E., Gomez, C., Gonzalez, A., Medel, O., Mendoza, L. and Perez, D.G. (2002) Cellular location and function of the P-glycoproteins (EhPgps) in Entamoeba histolytica multidrug-resistant trophozoites. Microb. Drug Resist. 8, 291-300
    • (2002) Microb. Drug Resist. , vol.8 , pp. 291-300
    • Banuelos, C.1    Orozco, E.2    Gomez, C.3    Gonzalez, A.4    Medel, O.5    Mendoza, L.6    Perez, D.G.7
  • 102
    • 0027984930 scopus 로고
    • Analysis of a single-domain P-glycoprotein-like gene in the early-diverging protist Trichomonas vaginalis
    • Johnson, P.J., Schuck, B.L. and Delgadillo, M.G. (1994) Analysis of a single-domain P-glycoprotein-like gene in the early-diverging protist Trichomonas vaginalis. Mol. Biochem. Parasitol. 66, 127-137
    • (1994) Mol. Biochem. Parasitol. , vol.66 , pp. 127-137
    • Johnson, P.J.1    Schuck, B.L.2    Delgadillo, M.G.3
  • 103
    • 0037899938 scopus 로고    scopus 로고
    • Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar
    • Albonico, M., Bickle, Q., Ramsan, M., Montresor, A., Savioli, L. and Taylor, M. (2003) Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar. Bull. W.H.O. 81, 343-352
    • (2003) Bull. W.H.O. , vol.81 , pp. 343-352
    • Albonico, M.1    Bickle, Q.2    Ramsan, M.3    Montresor, A.4    Savioli, L.5    Taylor, M.6
  • 104
    • 0032902055 scopus 로고    scopus 로고
    • Comparison of the efficacy of mebendazole, albendazole and pyrantel in treatment of human hookworm infections in the southern region of Mali, West Africa
    • Sacko, M., De Clercq, D., Behnke, J.M., Gilbert, F.S., Dorny, P. and Vercruysse, J. (1999) Comparison of the efficacy of mebendazole, albendazole and pyrantel in treatment of human hookworm infections in the southern region of Mali, West Africa. Trans. R. Soc. Trop. Med. Hyg. 93, 195-203
    • (1999) Trans. R. Soc. Trop. Med. Hyg. , vol.93 , pp. 195-203
    • Sacko, M.1    De Clercq, D.2    Behnke, J.M.3    Gilbert, F.S.4    Dorny, P.5    Vercruysse, J.6
  • 105
    • 57049129327 scopus 로고    scopus 로고
    • Praziquantel: Mechanisms of action, resistance and new derivatives for schistosomiasis
    • Doenhoff, M.J., Cioli, D. and Utzinger, J. (2008) Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis. Curr. Opin. Infect. Dis. 21, 659-667
    • (2008) Curr. Opin. Infect. Dis. , vol.21 , pp. 659-667
    • Doenhoff, M.J.1    Cioli, D.2    Utzinger, J.3
  • 106
    • 33748062666 scopus 로고    scopus 로고
    • The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux
    • Hayeshi, R., Masimirembwa, C., Mukanganyama, S. and Ungell, A.L. (2006) The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux. Eur. J. Pharm. Sci. 29, 70-81
    • (2006) Eur. J. Pharm. Sci. , vol.29 , pp. 70-81
    • Hayeshi, R.1    Masimirembwa, C.2    Mukanganyama, S.3    Ungell, A.L.4
  • 109
    • 75149198677 scopus 로고    scopus 로고
    • Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel
    • Kasinathan, R.S., Goronga, T., Messerli, S.M., Webb, T.R. and Greenberg, R.M. (2010) Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel. FASEB J. 24, 128-135
    • (2010) FASEB J. , vol.24 , pp. 128-135
    • Kasinathan, R.S.1    Goronga, T.2    Messerli, S.M.3    Webb, T.R.4    Greenberg, R.M.5
  • 110
    • 67650373884 scopus 로고    scopus 로고
    • Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility
    • Messerli, S.M., Kasinathan, R.S., Morgan, W., Spranger, S. and Greenberg, R.M. (2009) Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility. Mol. Biochem. Parasitol. 167, 54-59
    • (2009) Mol. Biochem. Parasitol. , vol.167 , pp. 54-59
    • Messerli, S.M.1    Kasinathan, R.S.2    Morgan, W.3    Spranger, S.4    Greenberg, R.M.5
  • 112
    • 0028244986 scopus 로고
    • Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins
    • Bosch, I.B., Wang, Z.X., Tao, L.F. and Shoemaker, C.B. (1994) Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins. Mol. Biochem. Parasitol. 65, 351-356
    • (1994) Mol. Biochem. Parasitol. , vol.65 , pp. 351-356
    • Bosch, I.B.1    Wang, Z.X.2    Tao, L.F.3    Shoemaker, C.B.4
  • 113
    • 0035450813 scopus 로고    scopus 로고
    • Genetic variability following selection of Haemonchus contortus with anthelmintics
    • Prichard, R. (2001) Genetic variability following selection of Haemonchus contortus with anthelmintics. Trends Parasitol. 17, 445-453
    • (2001) Trends Parasitol. , vol.17 , pp. 445-453
    • Prichard, R.1
  • 114
    • 34250196496 scopus 로고    scopus 로고
    • Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: A two-phase epidemiological study
    • Osei-Atweneboana, M.Y., Eng, J.K., Boakye, D.A., Gyapong, J.O. and Prichard, R.K. (2007) Prevalence and intensity of Onchocerca volvulus infection and efficacy of ivermectin in endemic communities in Ghana: a two-phase epidemiological study. Lancet 369, 2021-2029
    • (2007) Lancet , vol.369 , pp. 2021-2029
    • Osei-Atweneboana, M.Y.1    Eng, J.K.2    Boakye, D.A.3    Gyapong, J.O.4    Prichard, R.K.5
  • 116
    • 34347399591 scopus 로고    scopus 로고
    • ABC transporters and β-tubulin in macrocyclic lactone resistance: Prospects for marker development
    • Prichard, R.K. and Roulet, A. (2007) ABC transporters and β-tubulin in macrocyclic lactone resistance: prospects for marker development. Parasitology 134, 1123-1132
    • (2007) Parasitology , vol.134 , pp. 1123-1132
    • Prichard, R.K.1    Roulet, A.2
  • 117
    • 28044444352 scopus 로고    scopus 로고
    • Characterization of a half-size ATP-binding cassette transporter gene which may be a useful marker for ivermectin selection in Onchocerca volvulus
    • Ardelli, B.F., Guerriero, S.B. and Prichard, R.K. (2006) Characterization of a half-size ATP-binding cassette transporter gene which may be a useful marker for ivermectin selection in Onchocerca volvulus. Mol. Biochem. Parasitol. 145, 94-100
    • (2006) Mol. Biochem. Parasitol. , vol.145 , pp. 94-100
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 119
    • 22844449116 scopus 로고    scopus 로고
    • Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein
    • Ardelli, B.F., Guerriero, S.B. and Prichard, R.K. (2005) Genomic organization and effects of ivermectin selection on Onchocerca volvulus P-glycoprotein. Mol. Biochem. Parasitol. 143, 58-66
    • (2005) Mol. Biochem. Parasitol. , vol.143 , pp. 58-66
    • Ardelli, B.F.1    Guerriero, S.B.2    Prichard, R.K.3
  • 120
    • 3142630022 scopus 로고    scopus 로고
    • Identification of variant ABC-transporter genes among Onchocerca volvulus collected from ivermectin-treated and untreated patients in Ghana, West Africa
    • Ardelli, B.F. and Prichard, R.K. (2004) Identification of variant ABC-transporter genes among Onchocerca volvulus collected from ivermectin-treated and untreated patients in Ghana, West Africa. Ann. Trop. Med. Parasitol. 98, 371-384
    • (2004) Ann. Trop. Med. Parasitol. , vol.98 , pp. 371-384
    • Ardelli, B.F.1    Prichard, R.K.2
  • 121
    • 0032753556 scopus 로고    scopus 로고
    • Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the efficacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus)
    • Molento, M.B. and Prichard, R.K. (1999) Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the efficacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus). Parasitol. Res. 85, 1007-1011
    • (1999) Parasitol. Res. , vol.85 , pp. 1007-1011
    • Molento, M.B.1    Prichard, R.K.2
  • 122
    • 57649087686 scopus 로고    scopus 로고
    • Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans
    • James, C.E. and Davey, M.W. (2009) Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans. Int. J. Parasitol. 39, 213-220
    • (2009) Int. J. Parasitol. , vol.39 , pp. 213-220
    • James, C.E.1    Davey, M.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.