Quinacrine and a novel apigenin dimer can synergistically increase the pentamidine susceptibility of the protozoan parasite Leishmania

Journal of Antimicrobial Chemotherapy

Volumn 63, Issue 6, 2009, Pages 1179-1190

  Wong, Iris L K ^a,b   Chan, Kin Fai ^a,b   Zhao, Yunzhe ^a,b   Chan, Tak Hang ^a,b   Chow, Larry M C ^a,b  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

Author keywords

Drug efflux; Flavonoids; Reversal of resistance

Indexed keywords

ABC TRANSPORTER; APIGENIN; MEPACRINE; PENTAMIDINE; QUINIDINE; QUININE; STIBOGLUCONATE SODIUM; VERAPAMIL; VINBLASTINE;

ANIMAL CELL; ANTIBIOTIC SENSITIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; LEISHMANIA; LEISHMANIA DONOVANI; LEISHMANIASIS; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN;

ANIMALS; ANTIPROTOZOAL AGENTS; APIGENIN; DRUG RESISTANCE; DRUG SYNERGISM; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; LEISHMANIA ENRIETTII; PENTAMIDINE; QUINACRINE;

EID: 65749103218     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkp130     Document Type: Article

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