Functional genetic identification of PRP1, an ABC transporter superfamily member conferring pentamidine resistance in Leishmania major

Molecular and Biochemical Parasitology

Volumn 130, Issue 2, 2003, Pages 83-90

  Coelho, Adriano C ^a   Beverley, Stephen M ^b   Cotrim, Paulo C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drug resistance; Gene transfection; Leishmania major; Overexpression; P glycoprotein; Pentamidine

Indexed keywords

ABC TRANSPORTER; ANTIMONY DERIVATIVE; CYCLOSPORIN A; DIMER; GENOMIC DNA; GLYCOPROTEIN P; MEGLUMINE ANTIMONATE; MILTEFOSINE; MULTIDRUG RESISTANCE PROTEIN; NUCLEOTIDE; PENTAMIDINE; PENTAMIDINE RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG; VERAPAMIL;

AMINO ACID COMPOSITION; ARTICLE; BINDING SITE; CONTROLLED STUDY; COSMID; CROSS RESISTANCE; DRUG RESISTANCE; GENE DELETION; GENE FUNCTION; GENE IDENTIFICATION; GENE INSERTION; GENE LIBRARY; GENE LOCUS; GENE MAPPING; GENE OVEREXPRESSION; GENETIC CODE; GENETIC SCREENING; GENETIC TRANSFECTION; IC 50; LEISHMANIA MAJOR; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PREDICTION; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN DOMAIN; PROTEIN FAMILY; PROTOZOAL GENETICS; SITE DIRECTED MUTAGENESIS; TRANSPOSON; WILD TYPE;

LEISHMANIA MAJOR; TRANSPOSONS;

EID: 0142106997     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(03)00162-2     Document Type: Article

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