Antimalarial drugs: Recent advances in molecular determinants of resistance and their clinical significance

Cellular and Molecular Life Sciences

Volumn 63, Issue 14, 2006, Pages 1586-1596

  Woodrow, C J ^a   Krishna, S ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Artemisinins; Malaria; Mefloquine; Molecular markers; PfATP6; pfcrt; pfmdr1; Resistance

Indexed keywords

AMINOALCOHOL; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ; BENFLUMETOL; CHLOROQUINE; MEFLOQUINE; MOLECULAR MARKER; QUININE;

ANTIMALARIAL ACTIVITY; GENE AMPLIFICATION; GENE MUTATION; GENETIC TRANSFECTION; IC 50; MALARIA; MOLECULAR GENETICS; NONHUMAN; PLASMODIUM FALCIPARUM; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT OUTCOME;

AFRICA; AMINO ALCOHOLS; ANIMALS; ANTIMALARIALS; ARTEMISININS; ASIA, SOUTHEASTERN; BIOLOGICAL TRANSPORT; CALCIUM-TRANSPORTING ATPASES; CHLOROQUINE; DRUG RESISTANCE; DRUG RESISTANCE, MULTIPLE; DRUG THERAPY, COMBINATION; GENE AMPLIFICATION; HUMANS; MALARIA, FALCIPARUM; MEFLOQUINE; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTOZOAN PROTEINS; QUININE; SESQUITERPENES;

PLASMODIUM FALCIPARUM;

EID: 33746676404     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-006-6071-1     Document Type: Review

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