메뉴 건너뛰기




Volumn 49, Issue 4, 2003, Pages 977-989

Multiple transporters associated with malaria parasite responses to chloroquine and quinine

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CHLOROQUINE; GLYCOPROTEIN P; PROTEIN PFCRT; PROTEIN PFMDR1; QUININE; UNCLASSIFIED DRUG;

EID: 10744231302     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2003.03627.x     Document Type: Article
Times cited : (226)

References (43)
  • 1
    • 0034827271 scopus 로고    scopus 로고
    • Plasmodium falciparum: Linkage disequilibrium between loci in chromosomes 7 and 5 and chloroquine selective pressure in Northern Nigeria
    • Adagut, I.S., and Warhurst, D.C. (2001) Plasmodium falciparum: linkage disequilibrium between loci in chromosomes 7 and 5 and chloroquine selective pressure in Northern Nigeria. Parasitology 123: 219-224.
    • (2001) Parasitology , vol.123 , pp. 219-224
    • Adagut, I.S.1    Warhurst, D.C.2
  • 2
    • 0034667390 scopus 로고    scopus 로고
    • Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance
    • Allen, J.D., Brinkhuis, R.F., van Deemter, L., Wijnholds, J., and Schinkel, A.H. (2000) Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance. Cancer Res 60: 5761-5766.
    • (2000) Cancer Res , vol.60 , pp. 5761-5766
    • Allen, J.D.1    Brinkhuis, R.F.2    Van Deemter, L.3    Wijnholds, J.4    Schinkel, A.H.5
  • 3
    • 0035873715 scopus 로고    scopus 로고
    • High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1
    • Babiker, H.A., Pringle, S.J., Abdel-Muhsin, A., Mackinnon, M., Hunt, P., and Walliker, D. (2001) High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance gene pfmdr1. J Infect Dis 183: 1535-1538.
    • (2001) J Infect Dis , vol.183 , pp. 1535-1538
    • Babiker, H.A.1    Pringle, S.J.2    Abdel-Muhsin, A.3    Mackinnon, M.4    Hunt, P.5    Walliker, D.6
  • 4
    • 0031721984 scopus 로고    scopus 로고
    • Haemonchus contortus: Selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains
    • Blackhall, W.J., Pouliot, J.F., Prichard, R.K., and Beech, R.N. (1998) Haemonchus contortus: selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains. Exp Parasitol 90: 42-48.
    • (1998) Exp Parasitol , vol.90 , pp. 42-48
    • Blackhall, W.J.1    Pouliot, J.F.2    Prichard, R.K.3    Beech, R.N.4
  • 5
    • 0032738452 scopus 로고    scopus 로고
    • Role of an ABC importer in mycobacterial drug resistance
    • Chakraborti, P.K., Bhatt, K., Banerjee, S.K., and Misra, P. (1999) Role of an ABC importer in mycobacterial drug resistance. Biosci Rep 19: 293-300.
    • (1999) Biosci Rep , vol.19 , pp. 293-300
    • Chakraborti, P.K.1    Bhatt, K.2    Banerjee, S.K.3    Misra, P.4
  • 6
    • 0036467783 scopus 로고    scopus 로고
    • Levels of chloroquine resistance in Plasmodium falciparum are determined by loci other than pfcrt and pfmdr1
    • Chen, N., Russell, B., Fowler, E., Peters, J., and Cheng, Q. (2002) Levels of chloroquine resistance in Plasmodium falciparum are determined by loci other than pfcrt and pfmdr1. J Infect Dis 185: 405-407.
    • (2002) J Infect Dis , vol.185 , pp. 405-407
    • Chen, N.1    Russell, B.2    Fowler, E.3    Peters, J.4    Cheng, Q.5
  • 7
    • 0028151261 scopus 로고
    • Empirical threshold values for quantitative trait mapping
    • Churchill, G.A., and Doerge, R.W. (1994) Empirical threshold values for quantitative trait mapping. Genetics 138: 963-971.
    • (1994) Genetics , vol.138 , pp. 963-971
    • Churchill, G.A.1    Doerge, R.W.2
  • 8
    • 18244396971 scopus 로고    scopus 로고
    • Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum
    • Cooper, R.A., Ferdig, M.T., Su, X.Z., Ursos, L.M., Mu, J., Nomura, T., et al. (2002) Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum. Mol Pharmacol 61: 35-42.
    • (2002) Mol Pharmacol , vol.61 , pp. 35-42
    • Cooper, R.A.1    Ferdig, M.T.2    Su, X.Z.3    Ursos, L.M.4    Mu, J.5    Nomura, T.6
  • 9
    • 0034917716 scopus 로고    scopus 로고
    • The human atp-binding cassette (abc) transporter superfamily
    • Dean, M., Rzhetsky, A., and Allikmets, R. (2001) The human atp-binding cassette (abc) transporter superfamily. Genome Res 11: 1156-1166.
    • (2001) Genome Res , vol.11 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 10
    • 0034646245 scopus 로고    scopus 로고
    • The genetics of ivermectin resistance in Caenorhabditis elegans
    • Dent, J.A., Smith, M.M., Vassilatis, D.K., and Avery, L. (2000) The genetics of ivermectin resistance in Caenorhabditis elegans. Proc Natl Acad Sci USA 97: 2674-2679.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2674-2679
    • Dent, J.A.1    Smith, M.M.2    Vassilatis, D.K.3    Avery, L.4
  • 12
    • 0030896558 scopus 로고    scopus 로고
    • Evidence for selection for the tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum by chloroquine and amodiaquine
    • Duraisingh, M.T., Drakeley, C.J., Muller, O., Bailey, R., Snounou, G., Targett, G.A., et al. (1997) Evidence for selection for the tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum by chloroquine and amodiaquine. Parasitology 114: 205-211.
    • (1997) Parasitology , vol.114 , pp. 205-211
    • Duraisingh, M.T.1    Drakeley, C.J.2    Muller, O.3    Bailey, R.4    Snounou, G.5    Targett, G.A.6
  • 13
    • 0033636607 scopus 로고    scopus 로고
    • Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chioroquine resistance
    • Fidock, D.A., Nomura, T., Talley, A.K., Cooper, R.A., Dzekunov, S.M., Ferdig, M.T., et al. (2000) Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chioroquine resistance. Mol Cell 6: 861-871.
    • (2000) Mol Cell , vol.6 , pp. 861-871
    • Fidock, D.A.1    Nomura, T.2    Talley, A.K.3    Cooper, R.A.4    Dzekunov, S.M.5    Ferdig, M.T.6
  • 14
    • 0025269612 scopus 로고
    • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
    • Foote, S.J., Kyle, D.E., Martin, R.K., Oduola, A.M., Forsyth, K., Kemp, D.J., et al. (1990) Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345: 255-258.
    • (1990) Nature , vol.345 , pp. 255-258
    • Foote, S.J.1    Kyle, D.E.2    Martin, R.K.3    Oduola, A.M.4    Forsyth, K.5    Kemp, D.J.6
  • 15
    • 0037015614 scopus 로고    scopus 로고
    • Genome sequence of the human malaria parasite Plasmodium falciparum
    • Gardner, M.J., Hall, N., Fung, E., White, O., Berriman, M., Hyman, R.W., et al. (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419: 498-511.
    • (2002) Nature , vol.419 , pp. 498-511
    • Gardner, M.J.1    Hall, N.2    Fung, E.3    White, O.4    Berriman, M.5    Hyman, R.W.6
  • 16
    • 0023693805 scopus 로고
    • Response of Kampuchean strains of Plasmodium falciparum to antimalarials: In vivo assessment of quinine and quinine plus tetracycline; multiple drug resistance in vitro
    • Giboda, M., and Denis, M.B. (1988) Response of Kampuchean strains of Plasmodium falciparum to antimalarials: in vivo assessment of quinine and quinine plus tetracycline; multiple drug resistance in vitro. J Trop Med Hyg 91: 205-211.
    • (1988) J Trop Med Hyg , vol.91 , pp. 205-211
    • Giboda, M.1    Denis, M.B.2
  • 17
    • 0000803388 scopus 로고
    • The population frequencies of species and the estimation of population parameters
    • Good, I.J. (1953) The population frequencies of species and the estimation of population parameters. Biometrika 40. 237-264.
    • (1953) Biometrika , vol.40 , pp. 237-264
    • Good, I.J.1
  • 18
    • 0035711599 scopus 로고    scopus 로고
    • Mutation and linkage disequilibrium in human mtDNA
    • Hedrick, P., and Kumar, S. (2001) Mutation and linkage disequilibrium in human mtDNA. Eur J Hum Genet 9: 969-972.
    • (2001) Eur J Hum Genet , vol.9 , pp. 969-972
    • Hedrick, P.1    Kumar, S.2
  • 19
    • 0021344032 scopus 로고
    • The relationship between the in vitro response of Plasmodium falciparum to chloroquine, quinine and mefloquine
    • Knowles, G., Davidson, W.L., Jolley, D., and Alpers, M.P. (1984) The relationship between the in vitro response of Plasmodium falciparum to chloroquine, quinine and mefloquine. Trans R Soc Trop Med Hyg 78: 146-150.
    • (1984) Trans R Soc Trop Med Hyg , vol.78 , pp. 146-150
    • Knowles, G.1    Davidson, W.L.2    Jolley, D.3    Alpers, M.P.4
  • 20
    • 0036295212 scopus 로고    scopus 로고
    • Classification and evolution of P-loop GTPases and related ATPases
    • Leipe, D.D., Wolf, Y.I., Koonin, E.V., and Aravind, L. (2002) Classification and evolution of P-loop GTPases and related ATPases. J Mol Biol 317: 41-72.
    • (2002) J Mol Biol , vol.317 , pp. 41-72
    • Leipe, D.D.1    Wolf, Y.I.2    Koonin, E.V.3    Aravind, L.4
  • 21
    • 0000951097 scopus 로고
    • The evolutionary dynamics of complex polymorphisms
    • Lewontin, R.C., and Kojima, K. (1960) The evolutionary dynamics of complex polymorphisms. Evolution 14: 450-472.
    • (1960) Evolution , vol.14 , pp. 450-472
    • Lewontin, R.C.1    Kojima, K.2
  • 22
    • 0032827782 scopus 로고    scopus 로고
    • The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits
    • Long, A.D., and Langley, C.H. (1999) The power of association studies to detect the contribution of candidate genetic loci to variation in complex traits. Genome Res 9: 720-731.
    • (1999) Genome Res , vol.9 , pp. 720-731
    • Long, A.D.1    Langley, C.H.2
  • 23
    • 0025308653 scopus 로고
    • Falciparum malaria resistant to quinine and pyrimethamine-sulfadoxine successfully treated with mefloquine
    • Malin, A.S., and Hall, A.P. (1990) Falciparum malaria resistant to quinine and pyrimethamine-sulfadoxine successfully treated with mefloquine. Br Med J 300: 1175.
    • (1990) Br Med J , vol.300 , pp. 1175
    • Malin, A.S.1    Hall, A.P.2
  • 24
    • 0037130233 scopus 로고    scopus 로고
    • Chromosome-wide SNPs reveal an ancient origin for Plasmodium falciparum
    • Mu, J., Duan, J., Makova, K., Joy, D.A., Huynh, C.Q., Branch, O.H., et al. (2002) Chromosome-wide SNPs reveal an ancient origin for Plasmodium falciparum. Nature 418: 323-326.
    • (2002) Nature , vol.418 , pp. 323-326
    • Mu, J.1    Duan, J.2    Makova, K.3    Joy, D.A.4    Huynh, C.Q.5    Branch, O.H.6
  • 25
  • 27
    • 0025604232 scopus 로고
    • Drug resistance in malaria
    • Peters, W. (1990) Drug resistance in malaria. Recent Prog Med 81: 749-753.
    • (1990) Recent Prog Med , vol.81 , pp. 749-753
    • Peters, W.1
  • 29
    • 0034708162 scopus 로고    scopus 로고
    • Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
    • Reed, M.B., Saliba, K.J., Caruana, S.R., Kirk, K., and Cowman, A.F. (2000) Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature 403: 906-909.
    • (2000) Nature , vol.403 , pp. 906-909
    • Reed, M.B.1    Saliba, K.J.2    Caruana, S.R.3    Kirk, K.4    Cowman, A.F.5
  • 30
    • 0032972599 scopus 로고    scopus 로고
    • DnaSP, Version 3: An integrated program for molecular population genetics and molecular evolution analysis
    • Rozas, J., and Rozas, R. (1999) DnaSP, Version 3: an integrated program for molecular population genetics and molecular evolution analysis. Bioinformatics 15: 174-175.
    • (1999) Bioinformatics , vol.15 , pp. 174-175
    • Rozas, J.1    Rozas, R.2
  • 31
    • 0037020024 scopus 로고    scopus 로고
    • Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations
    • Sidhu, A.B., Verdier-Pinard, D., and Fidock, D.A. (2002) Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science 298: 210-213.
    • (2002) Science , vol.298 , pp. 210-213
    • Sidhu, A.B.1    Verdier-Pinard, D.2    Fidock, D.A.3
  • 32
    • 0032926986 scopus 로고    scopus 로고
    • Synergistic in vitro antimalarial activity of omeprazole and quinine
    • Skinner-Adams, T., and Davis, T.M. (1999) Synergistic in vitro antimalarial activity of omeprazole and quinine. Antimicrob Agents Chemother 43: 1304-1306.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1304-1306
    • Skinner-Adams, T.1    Davis, T.M.2
  • 33
    • 0031589733 scopus 로고    scopus 로고
    • Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa
    • Su, X., Kirkman, L.A., Fujioka, H., and Wellems, T.E. (1997) Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa. Cell 91: 593-603.
    • (1997) Cell , vol.91 , pp. 593-603
    • Su, X.1    Kirkman, L.A.2    Fujioka, H.3    Wellems, T.E.4
  • 34
    • 0032698219 scopus 로고    scopus 로고
    • A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum
    • Su, X., Ferdig, M.T., Huang, Y., Huynh, C.Q., Liu, A., You, J., et al. (1999) A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum. Science 286: 1351-1353.
    • (1999) Science , vol.286 , pp. 1351-1353
    • Su, X.1    Ferdig, M.T.2    Huang, Y.3    Huynh, C.Q.4    Liu, A.5    You, J.6
  • 35
    • 0031219571 scopus 로고    scopus 로고
    • A comparative study of artesunate and artemether in combination with mefloquine on multidrug resistant falciparum malaria in eastern Thailand
    • Thimasarn, K., Sirichaisinthop, J., Chanyakhun, P., Palananth, C., and Rooney, W. (1997) A comparative study of artesunate and artemether in combination with mefloquine on multidrug resistant falciparum malaria in eastern Thailand. SE Asian J Trop Med Public Health 28: 465-471.
    • (1997) SE Asian J Trop Med Public Health , vol.28 , pp. 465-471
    • Thimasarn, K.1    Sirichaisinthop, J.2    Chanyakhun, P.3    Palananth, C.4    Rooney, W.5
  • 36
    • 0032321841 scopus 로고    scopus 로고
    • Functional analysis of pfmdr1 gene of Plasmodium falciparum
    • Volkman, S., and Wirth, D. (1998) Functional analysis of pfmdr1 gene of Plasmodium falciparum. Methods Enzymol 292: 174-181.
    • (1998) Methods Enzymol , vol.292 , pp. 174-181
    • Volkman, S.1    Wirth, D.2
  • 37
    • 0041365515 scopus 로고    scopus 로고
    • WHO Expert Committee on Malaria
    • WHO (2000) WHO Expert Committee on Malaria. WHO Tech Rep Series 892: 1-74.
    • (2000) WHO Tech Rep Series , vol.892 , pp. 1-74
  • 38
    • 0024356582 scopus 로고
    • Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
    • Wilson, C.M., Serrano, A.E., Wasley, A, Bogenschutz, M.P., Shankar, A.H., and Wirth, D.F. (1989) Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 244: 1184-1186.
    • (1989) Science , vol.244 , pp. 1184-1186
    • Wilson, C.M.1    Serrano, A.E.2    Wasley, A.3    Bogenschutz, M.P.4    Shankar, A.H.5    Wirth, D.F.6
  • 39
    • 0027339057 scopus 로고
    • Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand
    • Wilson, C.M., Volkman, S.K., Thaithong, S., Martin, R.K., Kyle, D.E., Milhous, W.K., et al. (1993) Amplification of pfmdr 1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol Biochem Parasitol 57: 151-160.
    • (1993) Mol Biochem Parasitol , vol.57 , pp. 151-160
    • Wilson, C.M.1    Volkman, S.K.2    Thaithong, S.3    Martin, R.K.4    Kyle, D.E.5    Milhous, W.K.6
  • 40
    • 0030972285 scopus 로고    scopus 로고
    • In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials
    • Wongsrichanalai, C., Nguyen, T.D., Trieu, N.T., Wimonwattrawatee, T., Sookto, P., Heppner, D.G., et al. (1997) In vitro susceptibility of Plasmodium falciparum isolates in Vietnam to artemisinin derivatives and other antimalarials. Acta Trop 63: 151-158.
    • (1997) Acta Trop , vol.63 , pp. 151-158
    • Wongsrichanalai, C.1    Nguyen, T.D.2    Trieu, N.T.3    Wimonwattrawatee, T.4    Sookto, P.5    Heppner, D.G.6
  • 41
    • 0037130254 scopus 로고    scopus 로고
    • Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum
    • Wootton, J.C., Feng, X., Ferdig, M.T., Cooper, R.A., Mu, J., Baruch, D.I., et al. (2002) Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature 418: 320-323.
    • (2002) Nature , vol.418 , pp. 320-323
    • Wootton, J.C.1    Feng, X.2    Ferdig, M.T.3    Cooper, R.A.4    Mu, J.5    Baruch, D.I.6
  • 42
    • 0033990339 scopus 로고    scopus 로고
    • Model-free analysis and permutation tests for allelic associations
    • Zhao, J.H., Curtis, D., and Sham, P.C. (2000) Model-free analysis and permutation tests for allelic associations. Hum Hered 50: 133-139.
    • (2000) Hum Hered , vol.50 , pp. 133-139
    • Zhao, J.H.1    Curtis, D.2    Sham, P.C.3
  • 43
    • 0034798104 scopus 로고    scopus 로고
    • Population based linkage disequilibrium mapping of QTL: An application to simulated data in an isolated population
    • Zhao, J., Li, W., and Xiong, M.M. (2001) Population based linkage disequilibrium mapping of QTL: An application to simulated data in an isolated population. Genet Epidemiol 21 (Suppl. 1): s655-s659.
    • (2001) Genet Epidemiol , vol.21 , Issue.1 SUPPL.
    • Zhao, J.1    Li, W.2    Xiong, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.