Resistance to pentamidine in Leishmania mexicana involves exclusion of the drug from the mitochondrion

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 12, 2002, Pages 3731-3738

  Basselin, Mireille ^a,c   Denise, Hubert ^b   Coombs, Graham H ^a   Barrett, Michael P ^a,b  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; 3 AMINOBENZAMIDINE; 4 AMINOBENZAMIDINE; 4',6' DIAMIDINO 2 PHENYLINDOLE; ANTIPROTOZOAL AGENT; BAFILOMYCIN A1; BENZAMIDINE; BUTHIONINE SULFOXIMINE; DIAMIDINE DERIVATIVE; DICYCLOHEXYLCARBODIIMIDE; DIMINAZENE ACETURATE; GLYCOPROTEIN P; ISOMETAMIDIUM CHLORIDE; MONENSIN; N ETHYLMALEIMIDE; OLIGOMYCIN; ORTHOVANADIC ACID; OUABAIN; PENTAMIDINE DERIVATIVE; PENTAMIDINE ISETHIONATE; POLYAMINE; POTASSIUM CYANIDE; PROCHLORPERAZINE; PROPAMIDINE; STILBAMIDINE; TAUROCHOLIC ACID; THYMIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALINOMYCIN; VERAPAMIL; PENTAMIDINE;

AMASTIGOTE; ARTICLE; CONTROLLED STUDY; CROSS RESISTANCE; DRUG UPTAKE; KINETICS; LEISHMANIA MEXICANA; LEISHMANIASIS; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MULTIDRUG RESISTANCE; NONHUMAN; PARASITE; PHENOTYPE; PRIORITY JOURNAL; PROMASTIGOTE; PROTOZOAL INFECTION; ANIMAL; FLOW CYTOMETRY; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SPECIES DIFFERENCE;

ANIMALS; ANTIPROTOZOAL AGENTS; DRUG RESISTANCE, MULTIPLE; FLOW CYTOMETRY; LEISHMANIA MEXICANA; MITOCHONDRIA; PENTAMIDINE; SPECIES SPECIFICITY;

EID: 0036894232     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.12.3731-3738.2002     Document Type: Article

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