Alternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation

Journal of Biological Chemistry

Volumn 286, Issue 52, 2011, Pages 44988-44999

  Goodson, Michael L ^a   Mengeling, Brenda J ^a   Jonas, Brian A ^a,b   Privalsky, Martin L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTE DIFFERENTIATION; ADIPOCYTES; ADIPOGENESIS; ADIPOGENIC; BIOCHEMICAL PROPERTIES; BIOLOGICAL EFFECTS; COREPRESSORS; NUCLEAR RECEPTORS; SPLICE VARIANTS; TISSUE DISTRIBUTIONS; TRANSCRIPTIONAL PROGRAM;

TISSUE; TRANSCRIPTION FACTORS;

MOLECULAR WEIGHT;

MESSENGER RNA; NUCLEAR RECEPTOR COREPRESSOR; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR;

ADIPOCYTE; ADIPOGENESIS; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; GENETIC VARIABILITY; INHIBITION KINETICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ALTERNATIVE SPLICING; ANIMALS; CELL DIFFERENTIATION; MICE; NUCLEAR RECEPTOR CO-REPRESSOR 2; PROTEIN ISOFORMS; TRANSCRIPTION, GENETIC;

EID: 84455161762     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.291625     Document Type: Article

References (109)

1. Buranapramest, M., and Chakravarti, D. (2009) Prog Mol. Biol. Transl. Sci. 87, 193-234
2. Lonard, D. M., and O'malley, B. W. (2007) Mol. Cell 27, 691-700
3. Savkur, R. S., Bramlett, K. S., Clawson, D., and Burris, T. P. (2004) Vitam. Horm. 68, 145-183
4. Freiman, R. N., and Tjian, R. (2003) Cell 112, 11-17
5. Kraus, W. L., and Wong, J. (2002) Eur. J. Biochem. 269, 2275-2283
6. Lee, J. W., Lee, Y. C., Na, S. Y., Jung, D. J., and Lee, S. K. (2001) Cell. Mol. Life Sci. 58, 289-297
7. Oetting, A., and Yen, P. M. (2007) Best Pract. Res. Clin. Endocrinol. Metab. 21, 193-208
8. Rice, J. C., and Allis, C. D. (2001) Curr. Opin. Cell Biol. 13, 263-273
9. Tsai, C. C., and Fondell, J. D. (2004) Vitam. Horm. 68, 93-122
10. Wang, C., Powell, M. J., Popov, V. M., and Pestell, R. G. (2008) Mol. Endocrinol. 22, 539-545
11. Jones, P. L., and Shi, Y. B. (2003) Curr. Top. Microbiol. Immunol. 274, 237-268
12. Karagianni, P., and Wong, J. (2007) Oncogene 26, 5439-5449
13. Lazar, M. A. (2003) Nucl. Recept. Signal. 1, e001
14. Perissi, V., Jepsen, K., Glass, C. K., and Rosenfeld, M. G. (2010) Nat. Rev. Genet. 11, 109-123
15. Stanya, K. J., and Kao, H. Y. (2009) Cell Div. 4, 7
16. Alenghat, T., Yu, J., and Lazar, M. A. (2006) EMBO J. 25, 3966-3974
17. McKenna, N. J., and O'Malley, B. W. (2002) Endocrinology 143, 2461-2465
18. Muscat, G. E., Burke, L. J., and Downes, M. (1998) Nucleic Acids Res. 26, 2899-2907
19. Wong, C. W., and Privalsky, M. L. (1998) Mol. Cell. Biol. 18, 5500-5510
20. Chawla, A., Repa, J. J., Evans, R. M., and Mangelsdorf, D. J. (2001) Science 294, 1866-1870
21. Flamant, F., Baxter, J. D., Forrest, D., Refetoff, S., Samuels, H., Scanlan, T. S., Vennström, B., and Samarut, J. (2006) Pharmacol. Rev. 58, 705-711
22. Glass, C. K., and Saijo, K. (2010) Nat. Rev. Immunol. 10, 365-376
23. Hager, G. L. (2001) Prog. Nucleic Acids Res. Mol. Biol. 66, 279-305
24. McEwan, I. J. (2009) Methods Mol. Biol. 505, 3-18
25. Sonoda, J., Pei, L., and Evans, R. M. (2008) FEBS Lett. 582, 2-9
26. Cheng, S. Y., Leonard, J. L., and Davis, P. J. (2010) Endocr. Rev. 31, 139-170
27. Duong, V., Augereau, P., Badia, E., Jalaguier, S., and Cavailles, V. (2008) Adv. Exp. Med. Biol. 617, 121-127
28. Feige, J. N., and Auwerx, J. (2007) Trends Cell Biol. 17, 292-301
29. Hsia, E. Y., Goodson, M. L., Zou, J. X., Privalsky, M. L., and Chen, H. W. (2010) Adv. Drug Deliv. Rev. 62, 1227-1237
30. Privalsky, M. L. (2004) Annu. Rev. Physiol. 66, 315-360
31. Smith, C. L., and O'Malley, B. W. (2004) Endocr. Rev. 25, 45-71
32. Moehren, U., Eckey, M., and Baniahmad, A. (2004) Essays Biochem. 40, 89-104
33. Ordentlich, P., Downes, M., and Evans, R. M. (2001) Curr. Top. Microbiol. Immunol. 254, 101-116
34. Privalsky, M. L. (2008) in: NR Coregulators and Human Diseases (Kumar, R., and O'Malley, B. W., eds) pp. 243-280, World Scientific Publishing, Ltd., Singapore
35. Chen, H., and Privalsky, M. L. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 422-426
36. Hörlein, A. J., Näär, A. M., Heinzel, T., Torchia, J., Gloss, B., Kurokawa, R., Ryan, A., Kamei, Y., Söderström, M., and Glass, C. K. (1995) Nature 377, 397-404
37. Ordentlich, P., Downes, M., Xie, W., Genin, A., Spinner, N. B., and Evans, R. M. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 2639-2644
38. Sande, S., and Privalsky, M. L. (1996) Mol. Endocrinol. 10, 813-825
39. Seol, W., Mahon, M. J., Lee, Y. K., and Moore, D. D. (1996) Mol. Endocrinol. 10, 1646-1655
40. Alenghat, T., Meyers, K., Mullican, S. E., Leitner, K., Adeniji-Adele, A., Avila, J., Buan, M., Ahima, R. S., Kaestner, K. H., and Lazar, M. A. (2008) Nature 456, 997-1000
41. Downes, M., Ordentlich, P., Kao, H. Y., Alvarez, J. G., and Evans, R. M. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 10330-10335
42. Guenther, M. G., Barak, O., and Lazar, M. A. (2001) Mol. Cell. Biol. 21, 6091-6101
43. Ishizuka, T., and Lazar, M. A. (2003) Mol. Cell. Biol. 23, 5122-5131
44. Li, J., Wang, J., Wang, J., Nawaz, Z., Liu, J. M., Qin, J., and Wong, J. (2000) EMBO J. 19, 4342-4350
45. Nagy, L., Kao, H. Y., Chakravarti, D., Lin, R. J., Hassig, C. A., Ayer, D. E., Schreiber, S. L., and Evans, R. M. (1997) Cell 89, 373-380
46. Perissi, V., Aggarwal, A., Glass, C. K., Rose, D. W., and Rosenfeld, M. G. (2004) Cell 116, 511-526
47. Wen, Y. D., Perissi, V., Staszewski, L. M., Yang, W. M., Krones, A., Glass, C. K., Rosenfeld, M. G., and Seto, E. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 7202-7207
48. Yoon, H. G., Chan, D. W., Huang, Z. Q., Li, J., Fondell, J. D., Qin, J., and Wong, J. (2003) EMBO J. 22, 1336-1346
49. You, S. H., Liao, X., Weiss, R. E., and Lazar, M. A. (2010) Mol. Endocrinol. 24, 1359-1367
50. Burke, L. J., Downes, M., Laudet, V., and Muscat, G. E. (1998) Mol. Endocrinol. 12, 248-262
51. Hodgson, M. C., Shen, H. C., Hollenberg, A. N., and Balk, S. P. (2008) Mol. Cancer Ther. 7, 3187-3194
52. Hu, X., Li, Y., and Lazar, M. A. (2001) Mol. Cell. Biol. 21, 1747-1758
53. le Maire, A., Teyssier, C., Erb, C., Grimaldi, M., Alvarez, S., de Lera, A. R., Balaguer, P., Gronemeyer, H., Royer, C. A., Germain, P., and Bourguet, W. (2010) Nat. Struct. Mol. Biol. 17, 801-807
54. Makowski, A., Brzostek, S., Cohen, R. N., and Hollenberg, A. N. (2003) Mol. Endocrinol. 17, 273-286
55. Marimuthu, A., Feng, W., Tagami, T., Nguyen, H., Jameson, J. L., Fletterick, R. J., Baxter, J. D., and West, B. L. (2002) Mol. Endocrinol. 16, 271-286
56. Perissi, V., Staszewski, L. M., McInerney, E. M., Kurokawa, R., Krones, A., Rose, D. W., Lambert, M. H., Milburn, M. V., Glass, C. K., and Rosenfeld, M. G. (1999) Genes Dev. 13, 3198-3208
57. Phelan, C. A., Gampe, R. T., Jr., Lambert, M. H., Parks, D. J., Montana, V., Bynum, J., Broderick, T. M., Hu, X., Williams, S. P., Nolte, R. T., and Lazar, M. A. (2010) Nat. Struct. Mol. Biol. 17, 808-814
58. Webb, P., Anderson, C. M., Valentine, C., Nguyen, P., Marimuthu, A., West, B. L., Baxter, J. D., and Kushner, P. J. (2000) Mol. Endocrinol. 14, 1976-1985
59. Cohen, R. N., Brzostek, S., Kim, B., Chorev, M., Wondisford, F. E., and Hollenberg, A. N. (2001) Mol. Endocrinol. 15, 1049-1061
60. Downes, M., Burke, L. J., Bailey, P. J., and Muscat, G. E. (1996) Nucleic Acids Res. 24, 4379-4386
61. Varlakhanova, N., Snyder, C., Jose, S., Hahm, J. B., and Privalsky, M. L. (2010) Mol. Cell. Biol. 30, 1434-1445
62. Wong, C. W., and Privalsky, M. L. (1998) Mol. Cell. Biol. 18, 5724-5733
63. Faist, F., Short, S., Kneale, G. G., and Sharpe, C. R. (2009) Biosci. Rep. 29, 143-149
64. Goodson, M., Jonas, B. A., and Privalsky, M. A. (2005) Nucl. Recept. Signal 3, e003
65. Goodson, M. L., Jonas, B. A., and Privalsky, M. L. (2005) J. Biol. Chem. 280, 7493-7503
66. Jonas, B. A., Varlakhanova, N., Hayakawa, F., Goodson, M., and Privalsky, M. L. (2007) Mol. Endocrinol. 21, 1924-1939
67. Malartre, M., Short, S., and Sharpe, C. (2004) Nucleic Acids Res. 32, 4676-4686
68. Malartre, M., Short, S., and Sharpe, C. (2006) Dev. Biol. 292, 333-343
69. Mengeling, B. J., Phan, T. Q., Goodson, M. L., and Privalsky, M. L. (2011) J. Biol. Chem. 286, 4236-4247
70. Short, S., Malartre, M., and Sharpe, C. (2005) Biochem. Biophys. Res. Commun. 334, 845-852
71. Sutanto, M. M., Symons, M. S., and Cohen, R. N. (2007) Mol. Cell. Endocrinol. 267, 138-143
72. Poulos, S. P., Dodson, M. V., and Hausman, G. J. (2010) Exp. Biol. Med. 235, 1185-1193
73. Gimble, J. M., Robinson, C. E., Clarke, S. L., and Hill, M. R. (1998) Crit. Rev. Eukaryot. Gene Expr. 8, 141-168
74. Gurnell, M., Wentworth, J. M., Agostini, M., Adams, M., Collingwood, T. N., Provenzano, C., Browne, P. O., Rajanayagam, O., Burris, T. P., Schwabe, J. W., Lazar, M. A., and Chatterjee, V. K. (2000) J. Biol. Chem. 275, 5754-5759
75. Kumar, N., Solt, L. A., Wang, Y., Rogers, P. M., Bhattacharyya, G., Kamenecka, T. M., Stayrook, K. R., Crumbley, C., Floyd, Z. E., Gimble, J. M., Griffin, P. R., and Burris, T. P. (2010) Endocrinology 151, 3015-3025
76. Lahnalampi, M., Heinäniemi, M., Sinkkonen, L., Wabitsch, M., and Carlberg, C. (2010) PLoS One 5, e12991
77. Lehrke, M., and Lazar, M. A. (2005) Cell 123, 993-999
78. Mariash, C. N. (2003) J. Clin. Endocrinol. Metab. 88, 5603-5604
79. Obregon, M. J. (2008) Thyroid 18, 185-195
80. Wang, J., and Lazar, M. A. (2008) Mol. Cell. Biol. 28, 2213-2220
81. Willson, T. M., Lambert, M. H., and Kliewer, S. A. (2001) Annu. Rev. Biochem. 70, 341-367
82. Chawla, A., Schwarz, E. J., Dimaculangan, D. D., and Lazar, M. A. (1994) Endocrinology 135, 798-800
83. Guan, H. P., Ishizuka, T., Chui, P. C., Lehrke, M., and Lazar, M. A. (2005) Genes Dev. 19, 453-461
84. Jiang, W., Miyamoto, T., Kakizawa, T., Sakuma, T., Nishio, S., Takeda, T., Suzuki, S., and Hashizume, K. (2004) J. Endocrinol. 182, 295-302
85. Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A. (1995) J. Biol. Chem. 270, 12953-12956
86. Pantoja, C., Huff, J. T., and Yamamoto, K. R. (2008) Mol. Biol. Cell 19, 4032-4041
87. Nofsinger, R. R., Li, P., Hong, S. H., Jonker, J. W., Barish, G. D., Ying, H., Cheng, S. Y., Leblanc, M., Xu, W., Pei, L., Kang, Y. J., Nelson, M., Downes, M., Yu, R. T., Olefsky, J. M., Lee, C. H., and Evans, R. M. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 20021-20026
88. Sutanto, M. M., Ferguson, K. K., Sakuma, H., Ye, H., Brady, M. J., and Cohen, R. N. (2010) J. Biol. Chem. 285, 18485-18495
89. Yu, C., Markan, K., Temple, K. A., Deplewski, D., Brady, M. J., and Cohen, R. N. (2005) J. Biol. Chem. 280, 13600-13605
90. Student, A. K., Hsu, R. Y., and Lane, M. D. (1980) J. Biol. Chem. 255, 4745-4750
91. Kinkel, A. D., Fernyhough, M. E., Helterline, D. L., Vierck, J. L., Oberg, K. S., Vance, T. J., Hausman, G. J., Hill, R. A., and Dodson, M. V. (2004) Cytotechnology 46, 49-56
92. Collins, T. J. (2007) BioTechniques 43, S25-S30
93. Goodson, M. L., Farboud, B., and Privalsky, M. L. (2007) Nucl. Recept. Signal 5, e002
94. Todaro, G. J., and Green, H. (1963) J. Cell Biol. 17, 299-313
95. Astapova, I., Lee, L. J., Morales, C., Tauber, S., Bilban, M., and Hollenberg, A. N. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 19544-19549
96. Astapova, I., Vella, K. R., Ramadoss, P., Holtz, K. A., Rodwin, B. A., Liao, X. H., Weiss, R. E., Rosenberg, M. A., Rosenzweig, A., and Hollenberg, A. N. (2011) Mol. Endocrinol. 25, 212-224
97. Fang, S., Suh, J. M., Atkins, A. R., Hong, S. H., Leblanc, M., Nofsinger, R. R., Yu, R. T., Downes, M., and Evans, R. M. (2011) Proc. Natl. Acad. Sci. U.S.A. 108, 3412-3417
98. Hermanson, O., Glass, C. K., and Rosenfeld, M. G. (2002) Trends Endocrinol. Metab. 13, 55-60
99. Jepsen, K., Hermanson, O., Onami, T. M., Gleiberman, A. S., Lunyak, V., McEvilly, R. J., Kurokawa, R., Kumar, V., Liu, F., Seto, E., Hedrick, S. M., Mandel, G., Glass, C. K., Rose, D. W., and Rosenfeld, M. G. (2000) Cell 102, 753-763
100. Jepsen, K., Gleiberman, A. S., Shi, C., Simon, D. I., and Rosenfeld, M. G. (2008) Genes Dev. 22, 740-745
101. Cohen, R. N., Wondisford, F. E., and Hollenberg, A. N. (1998) Mol. Endocrinol. 12, 1567-1581
102. Oberste-Berghaus, C., Zanger, K., Hashimoto, K., Cohen, R. N., Hollenberg, A. N., and Wondisford, F. E. (2000) J. Biol. Chem. 275, 1787-1792
103. Rosen, M. D., and Privalsky, M. L. (2009) Mol. Endocrinol. 23, 1183-1192
104. Cheng, S. Y. (2005) Steroids 70, 450-454
105. Forrest, D., and Vennström, B. (2000) Thyroid 10, 41-52
106. Hashimoto, K., Curty, F. H., Borges, P. P., Lee, C. E., Abel, E. D., Elmquist, J. K., Cohen, R. N., and Wondisford, F. E. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 3998-4003
107. O'Shea, P. J., and Williams, G. R. (2002) J. Endocrinol. 175, 553-570
108. Wondisford, F. E. (2003) J. Investig. Med. 51, 215-220
109. Zhang, J., and Lazar, M. A. (2000) Annu. Rev. Physiol. 62, 439-466