Aberrant corepressor interactions implicated in PML-RARα and PLZF-RARα leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants

Journal of Biological Chemistry

Volumn 286, Issue 6, 2011, Pages 4236-4247

  Mengeling, Brenda J ^a   Phan, Theresa Q ^a   Goodson, Michael L ^a   Privalsky, Martin L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOMAL TRANSLOCATIONS; COACTIVATORS; COREPRESSORS; LEUKEMIC CELLS; LEUKEMOGENESIS; ONCOPROTEINS; PROMYELOCYTIC LEUKEMIA; RETINOIC ACID RECEPTORS; RETINOIC ACIDS; RETINOID X RECEPTOR; RETINOIDS; SPLICE VARIANTS; WILD TYPES;

TRANSCRIPTION FACTORS;

DISEASES;

NUCLEAR RECEPTOR COREPRESSOR; PROMYELOCYTIC LEUKEMIA PROTEIN RETINOIC ACID RECEPTOR ALPHA FUSION PROTEIN; PROMYELOCYTIC LEUKEMIA ZINC FINGER PROTEIN RETINOIC ACID RECEPTOR ALPHA FUSION PROTEIN; RETINOIC ACID RECEPTOR ALPHA; RETINOID; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; UNCLASSIFIED DRUG; NCOR1 PROTEIN, HUMAN; NCOR2 PROTEIN, HUMAN; ONCOPROTEIN; PLZF RARALPHA FUSION PROTEIN, HUMAN; PLZF-RARALPHA FUSION PROTEIN, HUMAN; PROMYELOCYTIC LEUKEMIA RETINOIC ACID RECEPTOR ALPHA FUSION ONCOPROTEIN; PROMYELOCYTIC LEUKEMIA-RETINOIC ACID RECEPTOR ALPHA FUSION ONCOPROTEIN; RECEPTOR INTERACTING PROTEIN 140;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME SPECIFICITY; HORMONE ACTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LEUKEMOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN SECRETION; RNA SPLICING; ANIMAL; CELL STRAIN HL 60; CELL STRAIN U937; GENETICS; METABOLISM; MOUSE;

ANIMALS; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MICE; NUCLEAR RECEPTOR CO-REPRESSOR 1; NUCLEAR RECEPTOR CO-REPRESSOR 2; ONCOGENE PROTEINS, FUSION; RETINOIDS; U937 CELLS;

EID: 79953001738     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.200964     Document Type: Article

References (48)

1. Privalsky, M. L. (2008) in NR Coregulators and Human Diseases (Kumar, R., and O'Malley, B. W., eds) pp. 243-280, World Scientific, Hackensack, NJ
2. Germain, P., Chambon, P., Eichele, G., Evans, R. M., Lazar, M. A., Leid, M., De Lera, A. R., Lotan, R., Mangelsdorf, D. J., and Gronemeyer, H. (2006) Pharmacol. Rev. 58, 712-725
3. Perissi, V., Jepsen, K., Glass, C. K., and Rosenfeld, M. G. (2010) Nat. Rev. Genet. 11, 109-123
4. Lazar, M. A. (2003) Nucl. Recept. Signal 1, e001
5. Ordentlich, P., Downes, M., and Evans, R. M. (2001) Curr. Top. Microbiol. Immunol. 254, 101-116
6. Collins, S. J. (2008) Curr. Opin. Hematol. 15, 346-351
7. Redner, R. L. (2002) Leukemia 16, 1927-1932
8. Minucci, S., Maccarana, M., Cioce, M., De Luca, P., Gelmetti, V., Segalla, S., Di Croce, L., Giavara, S., Matteucci, C., Gobbi, A., Bianchini, A., Colombo, E., Schiavoni, I., Badaracco, G., Hu, X., Lazar, M. A., Landsberger, N., Nervi, C., and Pelicci, P. G. (2000) Mol. Cell 5, 811-820
9. Lin, R. J., and Evans, R. M. (2000) Mol. Cell 5, 821-830
10. Guidez, F., Ivins, S., Zhu, J., Söderström, M., Waxman, S., and Zelent, A. (1998) Blood 91, 2634-2642
11. Sternsdorf, T., Phan, V. T., Maunakea, M. L., Ocampo, C. B., Sohal, J., Silletto, A., Galimi, F., Le Beau, M. M., Evans, R. M., and Kogan, S. C. (2006) Cancer Cell 9, 81-94
12. Kwok, C., Zeisig, B. B., Dong, S., and So, C. W. (2006) Cancer Cell 9, 95-108
13. Kakizuka, A., Miller, W. H., Jr., Umesono, K., Warrell, R. P., Jr., Frankel, S. R., Murty, V. V., Dmitrovsky, E., and Evans, R. M. (1991) Cell 66, 663-674
14. de Thé, H., Lavau, C., Marchio, A., Chomienne, C., Degos, L., and Dejean, A. (1991) Cell 66, 675-684
15. Sutanto, M. M., Symons, M. S., and Cohen, R. N. (2006) Mol. Cell Endocrinol. 259, 43-49
16. Short, S., Malartre, M., and Sharpe, C. (2005) Biochem. Biophys. Res. Commun. 334, 845-852
17. Goodson, M. L., Jonas, B. A., and Privalsky, M. L. (2005) J. Biol. Chem. 280, 7493-7503
18. Goodson, M., Jonas, B. A., and Privalsky, M. A. (2005) Nucl. Recept. Signal 3, e003
19. Martens, J. H., Brinkman, A. B., Simmer, F., Francoijs, K. J., Nebbioso, A., Ferrara, F., Altucci, L., and Stunnenberg, H. G. (2010) Cancer Cell 17, 173-185
20. Grignani, F., Ferrucci, P. F., Testa, U., Talamo, G., Fagioli, M., Alcalay, M., Mencarelli, A., Peschle, C., and Nicoletti, I. (1993) Cell 74, 423-431
21. Rosen, M. D., and Privalsky, M. L. (2009) Mol. Endocrinol. 23, 1183-1192
22. Mengeling, B. J., Lee, S., and Privalsky, M. L. (2008) Mol. Cell Endocrinol. 280, 47-62
23. Farboud, B., Hauksdottir, H., Wu, Y., and Privalsky, M. L. (2003) Mol. Cell Biol. 23, 2844-2858
24. Kogan, S. C., Hong, S. H., Shultz, D. B., Privalsky, M. L., and Bishop, J. M. (2000) Blood 95, 1541-1550
25. Malartre, M., Short, S., and Sharpe, C. (2004) Nucleic Acids Res. 32, 4676-4686
26. Lanotte, M., Martin-Thouvenin, V., Najman, S., Balerini, P., Valensi, F., and Berger, R. (1991) Blood 77, 1080-1086
27. Phan, T. Q., Jow, M. M., and Privalsky, M. L. (2010) Mol. Cell Endocrinol. 319, 88-98
28. Hauksdóttir, H., and Privalsky, M. L. (2001) Cell Growth Differ. 12, 85-98
29. Wong, C. W., and Privalsky, M. L. (1998) Mol. Cell Biol. 18, 5724-5733
30. Perez, A., Kastner, P., Sethi, S., Lutz, Y., Reibel, C., and Chambon, P. (1993) EMBO J. 12, 3171-3182
31. Xiao, J. H., Durand, B., Chambon, P., and Voorhees, J. J. (1995) J. Biol. Chem. 270, 3001-3011
32. Allenby, G., Janocha, R., Kazmer, S., Speck, J., Grippo, J. F., and Levin, A. A. (1994) J. Biol. Chem. 269, 16689-16695
33. Nasr, R., Lallemand-Breitenbach, V., Zhu, J., Guillemin, M. C., and de Thé, H. (2009) Clin. Cancer Res. 15, 6321-6326
34. Cohen, R. N., Brzostek, S., Kim, B., Chorev, M., Wondisford, F. E., and Hollenberg, A. N. (2001) Mol. Endocrinol. 15, 1049-1061
35. Cohen, R. N., Putney, A., Wondisford, F. E., and Hollenberg, A. N. (2000) Mol. Endocrinol. 14, 900-914
36. Perissi, V., Staszewski, L. M., McInerney, E. M., Kurokawa, R., Krones, A., Rose, D. W., Lambert, M. H., Milburn, M. V., Glass, C. K., and Rosenfeld, M. G. (1999) Genes Dev. 13, 3198-3208
37. Hu, X., and Lazar, M. A. (1999) Nature 402, 93-96
38. Zhang, J., Hu, X., and Lazar, M. A. (1999) Mol. Cell Biol. 19, 6448-6457
39. Zamir, I., Zhang, J., and Lazar, M. A. (1997) Genes Dev. 11, 835-846
40. Zhu, J., Nasr, R., Pérès, L., Riaucoux-Lormière, F., Honoré, N., Berthier, C., Kamashev, D., Zhou, J., Vitoux, D., Lavau, C., and de Thé, H. (2007) Cancer Cell 12, 23-35
41. Zeisig, B. B., Kwok, C., Zelent, A., Shankaranarayanan, P., Gronemeyer, H., Dong, S., and So, C. W. (2007) Cancer Cell 12, 36-51
42. Kamashev, D., Vitoux, D., and De Thé, H. (2004) J. Exp. Med. 199, 1163-1174
43. Lin, B. C., Wong, C. W., Chen, H. W., and Privalsky, M. L. (1997) J. Biol. Chem. 272, 9860-9987
44. Wang, K., Wang, P., Shi, J., Zhu, X., He, M., Jia, X., Yang, X., Qiu, F., Jin, W., Qian, M., Fang, H., Mi, J., Yang, X., Xiao, H., Minden, M., Du, Y., Chen, Z., and Zhang, J. (2010) Cancer Cell 17, 186-197
45. Zhou, J., Pérès, L., Honoré, N., Nasr, R., Zhu, J., and de Thé, H. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 9238-9243
46. Jonas, B. A., Varlakhanova, N., Hayakawa, F., Goodson, M., and Privalsky, M. L. (2007) Mol. Endocrinol. 21, 1924-1939
47. Jonas, B. A., and Privalsky, M. L. (2004) J. Biol. Chem. 279, 54676-54686
48. Hong, S. H., Yang, Z., and Privalsky, M. L. (2001) Mol. Cell Biol. 21, 7172-7182