SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 50, 2008, Pages 20021-20026

  Nofsinger, Russell R ^a   Li, Pingping ^b   Hong, Suk Hyun ^a   Jonker, Johan W ^a   Barish, Grant D ^a   Ying, Hao ^c   Cheng, Sheue Yann ^c   LeBlanc, Mathias ^a   Xu, Wei ^d   Pei, Liming ^a   Kang, Yeon Joo ^e   Nelson, Michael ^a   Downes, Michael ^a   Yu, Ruth T ^a   Olefsky, Jerrold M ^b   Lee, Chih Hao ^f   Evans, Ronald M ^a,g  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e BURNHAM INSTITUTE   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Adipogenesis; Corepressor; Glucose regulation; PPAR; TR

Indexed keywords

SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; DNA BINDING PROTEIN; GLUCOSE; NUCLEAR RECEPTOR CO-REPRESSOR 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REPRESSOR PROTEIN; THYROID HORMONE; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; UNCLASSIFIED DRUG;

ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; DEVELOPMENTAL DISORDER; DYSPNEA; EMBRYO; GLUCOSE METABOLISM; HORMONAL REGULATION; INSULIN SENSITIVITY; KNOCKOUT GENE; LETHALITY; MALE; METABOLIC DISORDER; METABOLIC REGULATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETICS; HOMEOSTASIS; LETHAL GENE; METABOLISM; MOUSE MUTANT; PROTEIN TERTIARY STRUCTURE;

MUS;

ADIPOGENESIS; ANIMALS; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; GENES, LETHAL; GLUCOSE; HOMEOSTASIS; MICE; MICE, MUTANT STRAINS; PPAR GAMMA; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA; THYROID HORMONES;

EID: 58149380715     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0811012105     Document Type: Article

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