-
1
-
-
0035048283
-
Critical role for thyroid hormone receptor beta2 in the regulation of paraventricular thyrotropin-releasing hormone neurons
-
Abel ED, Ahima RS, Boers ME, Elmquist JK, and Wondisford FE (2001) Critical role for thyroid hormone receptor beta2 in the regulation of paraventricular thyrotropin-releasing hormone neurons. J Clin Investig 107:1017-1023.
-
(2001)
J Clin Investig
, vol.107
, pp. 1017-1023
-
-
Abel, E.D.1
Ahima, R.S.2
Boers, M.E.3
Elmquist, J.K.4
Wondisford, F.E.5
-
2
-
-
16844368591
-
Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse
-
Angelin-Duclos C, Domenget C, Kolbus A, Beug H, Jurdic P, and Samarut J (2005) Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse. Development 132:925-934.
-
(2005)
Development
, vol.132
, pp. 925-934
-
-
Angelin-Duclos, C.1
Domenget, C.2
Kolbus, A.3
Beug, H.4
Jurdic, P.5
Samarut, J.6
-
3
-
-
0034744080
-
Polychlorinated biphenyls polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans as endocrine disrupters-what we have learned from Yusho disease
-
Aoki Y (2001) Polychlorinated biphenyls polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans as endocrine disrupters-what we have learned from Yusho disease. Environ Res 86:2-11.
-
(2001)
Environ Res
, vol.86
, pp. 2-11
-
-
Aoki, Y.1
-
4
-
-
30044433051
-
Discovery of small molecule inhibitors of the interaction of thyroid hormone receptor with transcriptional coregulators
-
Arnold LA, Estebanez-Perpina E, Togashi M, Jouravel N, Shelat A, McReynolds AC, Mar E, Nguyen P, Baxter JD, Fletterick RJ, et al. (2005) Discovery of small molecule inhibitors of the interaction of thyroid hormone receptor with transcriptional coregulators. J Biol Chem 280:43048-43055.
-
(2005)
J Biol Chem
, vol.280
, pp. 43048-43055
-
-
Arnold, L.A.1
Estebanez-Perpina, E.2
Togashi, M.3
Jouravel, N.4
Shelat, A.5
McReynolds, A.C.6
Mar, E.7
Nguyen, P.8
Baxter, J.D.9
Fletterick, R.J.10
-
5
-
-
0141895078
-
The molecular actions of thyroid hormone in bone
-
Bassett JH and Williams GR (2003) The molecular actions of thyroid hormone in bone. Trends Endocrinol Metab 14:356-364.
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 356-364
-
-
Bassett, J.H.1
Williams, G.R.2
-
6
-
-
1942453725
-
Selective activation of thyroid hormone signaling pathways by GC-1: A new approach to controlling cholesterol and body weight
-
Baxter JD, Webb P, Grover G, and Scanlan TS (2004) Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weight. Trends Endocrinol Metab 15:154-157.
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 154-157
-
-
Baxter, J.D.1
Webb, P.2
Grover, G.3
Scanlan, T.S.4
-
7
-
-
0026665611
-
Thyroid hormone receptor transcriptional activity is potentially autoregulated by truncated forms of the receptor
-
Bigler J, Hokanson W, and Eisenman RN (1992) Thyroid hormone receptor transcriptional activity is potentially autoregulated by truncated forms of the receptor. Mol Cell Biol 12:2406-2417.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 2406-2417
-
-
Bigler, J.1
Hokanson, W.2
Eisenman, R.N.3
-
8
-
-
0347364651
-
Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor
-
Borngraeber S, Budny MJ, Chiellini G, Cunha-Lima ST, Togashi M, Webb P, Baxter JD, Scanlan TS, and Fletterick RJ (2003) Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor. Proc Natl Acad Sci USA 100:15358-15363.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15358-15363
-
-
Borngraeber, S.1
Budny, M.J.2
Chiellini, G.3
Cunha-Lima, S.T.4
Togashi, M.5
Webb, P.6
Baxter, J.D.7
Scanlan, T.S.8
Fletterick, R.J.9
-
9
-
-
0033506827
-
A variant form of the nuclear triiodothyronine receptor c-ErbAalpha1 plays a direct role in regulation of mitochondrial RNA synthesis
-
Casas F, Rochard P, Rodier A, Cassar-Malek I, Marchal-Victorion S, Wiesner RJ, Cabello G, and Wrutniak C (1999) A variant form of the nuclear triiodothyronine receptor c-ErbAalpha1 plays a direct role in regulation of mitochondrial RNA synthesis. Mol Cell Biol 19:7913-7924.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 7913-7924
-
-
Casas, F.1
Rochard, P.2
Rodier, A.3
Cassar-Malek, I.4
Marchal-Victorion, S.5
Wiesner, R.J.6
Cabello, G.7
Wrutniak, C.8
-
10
-
-
0347356359
-
A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis-retinoic acid
-
Castillo AI, Sanchez-Martinez R, Moreno JL, Martinez-Iglesias OA, Palacios D, and Aranda A (2004) A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis-retinoic acid. Mol Cell Biol 24:502-513.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 502-513
-
-
Castillo, A.I.1
Sanchez-Martinez, R.2
Moreno, J.L.3
Martinez-Iglesias, O.A.4
Palacios, D.5
Aranda, A.6
-
11
-
-
1242341408
-
Thyroid hormone receptor mutations in cancer
-
Cheng SY (2003) Thyroid hormone receptor mutations in cancer. Mol Cell Endocrinol 213:23-30.
-
(2003)
Mol Cell Endocrinol
, vol.213
, pp. 23-30
-
-
Cheng, S.Y.1
-
12
-
-
0032541336
-
A role for helix 3 of the TRbeta ligand-binding domain in coactivator recruitment identified by characterization of a third cluster of mutations in resistance to thyroid hormone
-
Collingwood TN, Wagner R, Matthews CH, Clifton-Bligh RJ, Gurnell M, Rajanayagam O, Agostini M, Fletterick RJ, Beck-Peccoz P, Reinhardt W, et al. (1998) A role for helix 3 of the TRbeta ligand-binding domain in coactivator recruitment identified by characterization of a third cluster of mutations in resistance to thyroid hormone. EMBO (Eur Mol Biol Organ) J 17:4760-4770.
-
(1998)
EMBO (Eur Mol Biol Organ) J
, vol.17
, pp. 4760-4770
-
-
Collingwood, T.N.1
Wagner, R.2
Matthews, C.H.3
Clifton-Bligh, R.J.4
Gurnell, M.5
Rajanayagam, O.6
Agostini, M.7
Fletterick, R.J.8
Beck-Peccoz, P.9
Reinhardt, W.10
-
13
-
-
27144496093
-
Membrane receptors mediating thyroid hormone action
-
Davis PJ, Davis FB, and Cody V (2005) Membrane receptors mediating thyroid hormone action. Trends Endocrinol Metab 16:429-435.
-
(2005)
Trends Endocrinol Metab
, vol.16
, pp. 429-435
-
-
Davis, P.J.1
Davis, F.B.2
Cody, V.3
-
14
-
-
0032511086
-
Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors
-
Feng W, Ribeiro RC, Wagner RL, Nguyen H, Apriletti JW, Fletterick RJ, Baxter JD, Kushner PJ, and West BL (1998) Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science (Wash DC) 280:1747-1749.
-
(1998)
Science (Wash DC)
, vol.280
, pp. 1747-1749
-
-
Feng, W.1
Ribeiro, R.C.2
Wagner, R.L.3
Nguyen, H.4
Apriletti, J.W.5
Fletterick, R.J.6
Baxter, J.D.7
Kushner, P.J.8
West, B.L.9
-
15
-
-
0036138767
-
Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene
-
Flamant F, Poguet AL, Plateroti M, Chassande O, Gauthier K, Streichenberger N, Mansouri A, and Samarut J (2002) Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene. Mol Endocrinol 16:24-32.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 24-32
-
-
Flamant, F.1
Poguet, A.L.2
Plateroti, M.3
Chassande, O.4
Gauthier, K.5
Streichenberger, N.6
Mansouri, A.7
Samarut, J.8
-
16
-
-
0038407750
-
Thyroid hormone receptors: Lessons from knockout and knock-in mutant mice
-
Flamant F and Samarut J (2003) Thyroid hormone receptors: lessons from knockout and knock-in mutant mice. Trends Endocrinol Metab 14:85-90.
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 85-90
-
-
Flamant, F.1
Samarut, J.2
-
17
-
-
0035989243
-
Patterns of liver gene expression governed by TRbeta
-
Flores-Morales A, Gullberg H, Fernandez L, Stahlberg N, Lee NH, Vennstrom B, and Norstedt G (2002) Patterns of liver gene expression governed by TRbeta. Mol Endocrinol 16:1257-1268.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 1257-1268
-
-
Flores-Morales, A.1
Gullberg, H.2
Fernandez, L.3
Stahlberg, N.4
Lee, N.H.5
Vennstrom, B.6
Norstedt, G.7
-
18
-
-
0026557820
-
Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers homodimers or heterodimers
-
Forman BM, Casanova J, Raaka BM, Ghysdael J, and Samuels HH (1992) Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers homodimers or heterodimers. Mol Endocrinol 6:429-442.
-
(1992)
Mol Endocrinol
, vol.6
, pp. 429-442
-
-
Forman, B.M.1
Casanova, J.2
Raaka, B.M.3
Ghysdael, J.4
Samuels, H.H.5
-
19
-
-
0029947835
-
Thyroid hormone receptor beta is essential for development of auditory function
-
Forrest D, Erway LC, Ng L, Altschuler R, and Curran T (1996a) Thyroid hormone receptor beta is essential for development of auditory function. Nat Genet 13:354-357.
-
(1996)
Nat Genet
, vol.13
, pp. 354-357
-
-
Forrest, D.1
Erway, L.C.2
Ng, L.3
Altschuler, R.4
Curran, T.5
-
20
-
-
0029995572
-
Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: Evidence for tissue-specific modulation of receptor function
-
Forrest D, Hanebuth E, Smeyne RJ, Everds N, Stewart CL, Wehner JM, and Curran T (1996b) Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function. EMBO (Eur Mol Biol Organ) J 15:3006-3015.
-
(1996)
EMBO (Eur Mol Biol Organ) J
, vol.15
, pp. 3006-3015
-
-
Forrest, D.1
Hanebuth, E.2
Smeyne, R.J.3
Everds, N.4
Stewart, C.L.5
Wehner, J.M.6
Curran, T.7
-
21
-
-
0033950142
-
Functions of thyroid hormone receptors in mice
-
Forrest D and Vennstrom B (2000) Functions of thyroid hormone receptors in mice Thyroid 10:41-52.
-
(2000)
Thyroid
, vol.10
, pp. 41-52
-
-
Forrest, D.1
Vennstrom, B.2
-
22
-
-
12344251006
-
Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors
-
Gauger KJ, Kato Y, Haraguchi K, Lehmler HJ, Robertson LW, Bansal R, and Zoeller RT (2004) Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors. Environ Health Perspect 112:516-523.
-
(2004)
Environ Health Perspect
, vol.112
, pp. 516-523
-
-
Gauger, K.J.1
Kato, Y.2
Haraguchi, K.3
Lehmler, H.J.4
Robertson, L.W.5
Bansal, R.6
Zoeller, R.T.7
-
23
-
-
0034955661
-
Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus
-
Gauthier K, Plateroti M, Harvey CB, Williams GR, Weiss RE, Refetoff S, Willott JF, Sundin V, Roux JP, Malaval L, et al. (2001) Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus. Mol Cell Biol 21:4748-4760.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4748-4760
-
-
Gauthier, K.1
Plateroti, M.2
Harvey, C.B.3
Williams, G.R.4
Weiss, R.E.5
Refetoff, S.6
Willott, J.F.7
Sundin, V.8
Roux, J.P.9
Malaval, L.10
-
24
-
-
0042734823
-
Selective thyroid hormone receptor-beta activation: A strategy for reduction of weight cholesterol and lipoprotein (a) with reduced cardiovascular liability
-
Grover GJ, Mellstrom K, Ye L, Malm J, Li YL, Bladh LG, Sleph PG, Smith MA, George R, Vennstrom B, et al. (2003) Selective thyroid hormone receptor-beta activation: a strategy for reduction of weight cholesterol and lipoprotein (a) with reduced cardiovascular liability. Proc Natl Acad Sci USA 100:10067-10072.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10067-10072
-
-
Grover, G.J.1
Mellstrom, K.2
Ye, L.3
Malm, J.4
Li, Y.L.5
Bladh, L.G.6
Sleph, P.G.7
Smith, M.A.8
George, R.9
Vennstrom, B.10
-
25
-
-
0342813025
-
Transcriptional induction of RC3/neurogranin by thyroid hormone: Differential neuronal sensitivity is not correlated with thyroid hormone receptor distribution in the brain
-
Guadano-Ferraz A, Escamez MJ, Morte B, Vargiu P, and Bernal J (1997) Transcriptional induction of RC3/neurogranin by thyroid hormone: differential neuronal sensitivity is not correlated with thyroid hormone receptor distribution in the brain. Brain Res Mol Brain Res 49:37-44.
-
(1997)
Brain Res Mol Brain Res
, vol.49
, pp. 37-44
-
-
Guadano-Ferraz, A.1
Escamez, M.J.2
Morte, B.3
Vargiu, P.4
Bernal, J.5
-
26
-
-
0035957408
-
An unliganded thyroid hormone receptor causes severe neurological dysfunction
-
Hashimoto K, Curty FH, Borges PP, Lee CE, Abel ED, Elmquist JK, Cohen RN, and Wondisford FE (2001) An unliganded thyroid hormone receptor causes severe neurological dysfunction. Proc Natl Acad Sci USA 98:3998-4003.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3998-4003
-
-
Hashimoto, K.1
Curty, F.H.2
Borges, P.P.3
Lee, C.E.4
Abel, E.D.5
Elmquist, J.K.6
Cohen, R.N.7
Wondisford, F.E.8
-
27
-
-
18244365116
-
Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4- alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor
-
Hedfors A, Appelqvist T, Carlsson B, Bladh LG, Litten C, Agback P, Grynfarb M, Koehler KF, and Malm J (2005) Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4-alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor. J Med Chem 48:3114-3117.
-
(2005)
J Med Chem
, vol.48
, pp. 3114-3117
-
-
Hedfors, A.1
Appelqvist, T.2
Carlsson, B.3
Bladh, L.G.4
Litten, C.5
Agback, P.6
Grynfarb, M.7
Koehler, K.F.8
Malm, J.9
-
28
-
-
19944433730
-
Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor and effect on tadpole metamorphosis
-
Kitamura S, Kato T, Iida M, Jinno N, Suzuki T, Ohta S, Fujimoto N, Hanada H, Kashiwagi K, and Kashiwagi A (2005) Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: affinity to the mammalian thyroid hormone receptor and effect on tadpole metamorphosis. Life Sci 76:1589-1601.
-
(2005)
Life Sci
, vol.76
, pp. 1589-1601
-
-
Kitamura, S.1
Kato, T.2
Iida, M.3
Jinno, N.4
Suzuki, T.5
Ohta, S.6
Fujimoto, N.7
Hanada, H.8
Kashiwagi, K.9
Kashiwagi, A.10
-
29
-
-
25144509449
-
Regulation of type 1 iodothyronine deiodinase in health and disease
-
Koenig RJ (2005) Regulation of type 1 iodothyronine deiodinase in health and disease. Thyroid 15:835-840.
-
(2005)
Thyroid
, vol.15
, pp. 835-840
-
-
Koenig, R.J.1
-
30
-
-
19944399429
-
Ligand-receptor engineering and its application towards the complementation of genetic disease and target identification
-
Koh JT and Biggins JB (2005) Ligand-receptor engineering and its application towards the complementation of genetic disease and target identification. Curr Top Med Chem 5:413-420.
-
(2005)
Curr Top Med Chem
, vol.5
, pp. 413-420
-
-
Koh, J.T.1
Biggins, J.B.2
-
31
-
-
15444378492
-
Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties
-
Lee S and Privalsky ML (2005) Heterodimers of retinoic acid receptors and thyroid hormone receptors display unique combinatorial regulatory properties. Mol Endocrinol 19:863-878.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 863-878
-
-
Lee, S.1
Privalsky, M.L.2
-
32
-
-
0036318975
-
Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer
-
Li D, Li T, Wang F, Tian H, and Samuels HH (2002) Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer. Mol Cell Biol 22:5782-5792.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5782-5792
-
-
Li, D.1
Li, T.2
Wang, F.3
Tian, H.4
Samuels, H.H.5
-
33
-
-
1542379985
-
Novel roles of retinoid X receptor (RXR) and RXR ligand in dynamically modulating the activity of the thyroid hormone receptor/RXR heterodimer
-
Li D, Yamada T, Wang F, Vulin AI, and Samuels HH (2004) Novel roles of retinoid X receptor (RXR) and RXR ligand in dynamically modulating the activity of the thyroid hormone receptor/RXR heterodimer. J Biol Chem 279:7427-7437.
-
(2004)
J Biol Chem
, vol.279
, pp. 7427-7437
-
-
Li, D.1
Yamada, T.2
Wang, F.3
Vulin, A.I.4
Samuels, H.H.5
-
34
-
-
0141755180
-
A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice
-
Liu YY, Schultz JJ, and Brent GA (2003) A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem 278:38913-38920.
-
(2003)
J Biol Chem
, vol.278
, pp. 38913-38920
-
-
Liu, Y.Y.1
Schultz, J.J.2
Brent, G.A.3
-
35
-
-
3142655713
-
Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life
-
Mai W, Janier MF, Allioli N, Quignodon L, Chuzel T, Flamant F, and Samarut J (2004) Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life. Proc Natl Acad Sci USA 101:10332-10337.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10332-10337
-
-
Mai, W.1
Janier, M.F.2
Allioli, N.3
Quignodon, L.4
Chuzel, T.5
Flamant, F.6
Samarut, J.7
-
36
-
-
0036159939
-
TR surfaces and conformations required to bind nuclear receptor corepressor
-
Marimuthu A, Feng W, Tagami T, Nguyen H, Jameson JL, Fletterick RJ, Baxter JD, and West BL (2002) TR surfaces and conformations required to bind nuclear receptor corepressor. Mol Endocrinol 16:271-286.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 271-286
-
-
Marimuthu, A.1
Feng, W.2
Tagami, T.3
Nguyen, H.4
Jameson, J.L.5
Fletterick, R.J.6
Baxter, J.D.7
West, B.L.8
-
37
-
-
0037378483
-
Functional analysis of basic transcription element binding protein by gene targeting technology
-
Morita M, Kobayashi A, Yamashita T, Shimanuki T, Nakajima O, Takahashi S, Ikegami S, Inokuchi K, Yamashita K, Yamamoto M, et al. (2003) Functional analysis of basic transcription element binding protein by gene targeting technology. Mol Cell Biol 23:2489-2500.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2489-2500
-
-
Morita, M.1
Kobayashi, A.2
Yamashita, T.3
Shimanuki, T.4
Nakajima, O.5
Takahashi, S.6
Ikegami, S.7
Inokuchi, K.8
Yamashita, K.9
Yamamoto, M.10
-
38
-
-
0036847316
-
Thyroid hormone action is disrupted by bisphenol A as an antagonist
-
Moriyama K, Tagami T, Akamizu T, Usui T, Saijo M, Kanamoto N, Hataya Y, Shimatsu A, Kuzuya H, and Nakao K (2002) Thyroid hormone action is disrupted by bisphenol A as an antagonist. J Clin Endocrinol Metab 87:5185-5190.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 5185-5190
-
-
Moriyama, K.1
Tagami, T.2
Akamizu, T.3
Usui, T.4
Saijo, M.5
Kanamoto, N.6
Hataya, Y.7
Shimatsu, A.8
Kuzuya, H.9
Nakao, K.10
-
39
-
-
1842374475
-
Thyroid hormone-regulated expression of RC3/neurogranin in the immortalized hypothalamic cell line GT1-7
-
Morte B, Iniguez MA, Lorenzo PI, and Bernal J (1997) Thyroid hormone-regulated expression of RC3/neurogranin in the immortalized hypothalamic cell line GT1-7. J Neurochem 69:902-909.
-
(1997)
J Neurochem
, vol.69
, pp. 902-909
-
-
Morte, B.1
Iniguez, M.A.2
Lorenzo, P.I.3
Bernal, J.4
-
40
-
-
0037133686
-
Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism
-
Morte B, Manzano J, Scanlan T, Vennstrom B, and Bernal J (2002) Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism. Proc Natl Acad Sci USA 99:3985-3989.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3985-3989
-
-
Morte, B.1
Manzano, J.2
Scanlan, T.3
Vennstrom, B.4
Bernal, J.5
-
41
-
-
0035168148
-
A thyroid hormone receptor that is required for the development of green cone photoreceptors
-
Ng L, Hurley JB, Dierks B, Srinivas M, Salto C, Vennstrom B, Reh TA, and Forrest D (2001) A thyroid hormone receptor that is required for the development of green cone photoreceptors. Nat Genet 27:94-98.
-
(2001)
Nat Genet
, vol.27
, pp. 94-98
-
-
Ng, L.1
Hurley, J.B.2
Dierks, B.3
Srinivas, M.4
Salto, C.5
Vennstrom, B.6
Reh, T.A.7
Forrest, D.8
-
42
-
-
16844371411
-
Hammett analysis of selective thyroid hormone receptor modulators reveals structural and electronic requirements for hormone antagonists
-
Nguyen NH, Apriletti JW, Baxter JD, and Scanlan TS (2005) Hammett analysis of selective thyroid hormone receptor modulators reveals structural and electronic requirements for hormone antagonists. J Am Chem Soc 127:4599-4608.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 4599-4608
-
-
Nguyen, N.H.1
Apriletti, J.W.2
Baxter, J.D.3
Scanlan, T.S.4
-
43
-
-
0037130243
-
Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment
-
Nguyen NH, Apriletti JW, Cunha Lima ST, Webb P, Baxter JD, and Scanlan TS (2002) Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment. J Med Chem 45:3310-3320.
-
(2002)
J Med Chem
, vol.45
, pp. 3310-3320
-
-
Nguyen, N.H.1
Apriletti, J.W.2
Cunha Lima, S.T.3
Webb, P.4
Baxter, J.D.5
Scanlan, T.S.6
-
44
-
-
0038408989
-
Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Nishimura N, Yonemoto J, Miyabara Y, Sato M, and Tohyama C (2003) Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Endocrinology 144:2075-2083.
-
(2003)
Endocrinology
, vol.144
, pp. 2075-2083
-
-
Nishimura, N.1
Yonemoto, J.2
Miyabara, Y.3
Sato, M.4
Tohyama, C.5
-
45
-
-
16644373256
-
Crystallization and preliminary X-ray diffraction studies of isoform alpha1 of the human thyroid hormone receptor ligand-binding domain
-
Nunes FM, Aparicio R, Santos MA, Portugal RV, Dias SM, Neves FA, Simeoni LA, Baxter JD, Webb P, and Polikarpov I (2004) Crystallization and preliminary X-ray diffraction studies of isoform alpha1 of the human thyroid hormone receptor ligand-binding domain. Acta Crystallogr D Biol Crystallogr 60:1867-1870.
-
(2004)
Acta Crystallogr D Biol Crystallogr
, vol.60
, pp. 1867-1870
-
-
Nunes, F.M.1
Aparicio, R.2
Santos, M.A.3
Portugal, R.V.4
Dias, S.M.5
Neves, F.A.6
Simeoni, L.A.7
Baxter, J.D.8
Webb, P.9
Polikarpov, I.10
-
47
-
-
0034955247
-
Functional interference between thyroid hormone receptor alpha (TRalpha) and natural truncated TRdeltaalpha isoforms in the control of intestine development
-
Plateroti M, Gauthier K, Domon-Dell C, Freund JN, Samarut J, and Chassande O (2001) Functional interference between thyroid hormone receptor alpha (TRalpha) and natural truncated TRdeltaalpha isoforms in the control of intestine development. Mol Cell Biol 21:4761-4772.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4761-4772
-
-
Plateroti, M.1
Gauthier, K.2
Domon-Dell, C.3
Freund, J.N.4
Samarut, J.5
Chassande, O.6
-
48
-
-
7244223535
-
Thyroid hormone signaling is highly heterogeneous during preand postnatal brain development
-
Quignodon L, Legrand C, Allioli N, Guadano-Ferraz A, Bernal J, Samarut J, and Flamant F (2004) Thyroid hormone signaling is highly heterogeneous during preand postnatal brain development. J Mol Endocrinol 33:467-476.
-
(2004)
J Mol Endocrinol
, vol.33
, pp. 467-476
-
-
Quignodon, L.1
Legrand, C.2
Allioli, N.3
Guadano-Ferraz, A.4
Bernal, J.5
Samarut, J.6
Flamant, F.7
-
49
-
-
0029044997
-
Structural determinants of nuclear receptor assembly on DNA direct repeats
-
Rastinejad F, Perlmann T, Evans RM, and Sigler PB (1995) Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature (Lond) 375:203-211.
-
(1995)
Nature (Lond)
, vol.375
, pp. 203-211
-
-
Rastinejad, F.1
Perlmann, T.2
Evans, R.M.3
Sigler, P.B.4
-
50
-
-
0032052809
-
X-ray crystallographic and functional studies of thyroid hormone receptor
-
Ribeiro RC, Apriletti JW, Wagner RL, Feng W, Kushner PJ, Nilsson S, Scanlan TS, West BL, Fletterick RJ, and Baxter JD (1998) X-ray crystallographic and functional studies of thyroid hormone receptor. J Steroid Biochem Mol Biol 65:133-141.
-
(1998)
J Steroid Biochem Mol Biol
, vol.65
, pp. 133-141
-
-
Ribeiro, R.C.1
Apriletti, J.W.2
Wagner, R.L.3
Feng, W.4
Kushner, P.J.5
Nilsson, S.6
Scanlan, T.S.7
West, B.L.8
Fletterick, R.J.9
Baxter, J.D.10
-
51
-
-
0023025178
-
The c-erb-A protein is a high-affinity receptor for thyroid hormone
-
Sap J, Munoz A, Damm K, Goldberg Y, Ghysdael J, Leutz A, Beug H, and Vennstrom B (1986) The c-erb-A protein is a high-affinity receptor for thyroid hormone. Nature (Lond) 324:635-640.
-
(1986)
Nature (Lond)
, vol.324
, pp. 635-640
-
-
Sap, J.1
Munoz, A.2
Damm, K.3
Goldberg, Y.4
Ghysdael, J.5
Leutz, A.6
Beug, H.7
Vennstrom, B.8
-
52
-
-
0037495033
-
Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking
-
Schapira M, Raaka BM, Das S, Fan L, Totrov M, Zhou Z, Wilson SR, Abagyan R, and Samuels HH (2003) Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking. Proc Natl Acad Sci USA 100:7354-7359.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7354-7359
-
-
Schapira, M.1
Raaka, B.M.2
Das, S.3
Fan, L.4
Totrov, M.5
Zhou, Z.6
Wilson, S.R.7
Abagyan, R.8
Samuels, H.H.9
-
53
-
-
0029848197
-
Thyroid hormone-responsive genes in developing cerebellum include a novel synaptotagmin and a hairless homolog
-
Thompson CC (1996) Thyroid hormone-responsive genes in developing cerebellum include a novel synaptotagmin and a hairless homolog. J Neurosci 16:7832-7840.
-
(1996)
J Neurosci
, vol.16
, pp. 7832-7840
-
-
Thompson, C.C.1
-
54
-
-
0023227169
-
Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system
-
Thompson CC, Weinberger C, Lebo R, and Evans RM (1987) Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science (Wash DC) 237:1610-1614.
-
(1987)
Science (Wash DC)
, vol.237
, pp. 1610-1614
-
-
Thompson, C.C.1
Weinberger, C.2
Lebo, R.3
Evans, R.M.4
-
55
-
-
18644374062
-
Retardation of post-natal development caused by a negatively acting thyroid receptor alpha1
-
Tinnikov A, Nordström K, Thoren P, Kindblom JM, Malin S, Rozell B, Adams M, Rajanayagam O, Petterson S, Ohlsson C, et al. (2002) Retardation of post-natal development caused by a negatively acting thyroid receptor alpha1. EMBO (Eur Mol Biol Organ) J 21:1-9.
-
(2002)
EMBO (Eur Mol Biol Organ) J
, vol.21
, pp. 1-9
-
-
Tinnikov, A.1
Nordström, K.2
Thoren, P.3
Kindblom, J.M.4
Malin, S.5
Rozell, B.6
Adams, M.7
Rajanayagam, O.8
Petterson, S.9
Ohlsson, C.10
-
56
-
-
0029047556
-
Desethylamiodarone is a competitive inhibitor of the binding of thyroid hormone to the thyroid hormone alpha 1-receptor protein
-
van Beeren HC, Bakker O, and Wiersinga WM (1995) Desethylamiodarone is a competitive inhibitor of the binding of thyroid hormone to the thyroid hormone alpha 1-receptor protein. Mol Cell Endocrinol 112:15-19.
-
(1995)
Mol Cell Endocrinol
, vol.112
, pp. 15-19
-
-
Van Beeren, H.C.1
Bakker, O.2
Wiersinga, W.M.3
-
57
-
-
0029953792
-
Structure-function relationship of the inhibition of the 3,5,3′-triiodothyronine binding to the alpha1- and beta1-thyroid hormone receptor by amiodarone analogs
-
van Beeren HC, Bakker O, and Wiersinga WM (1996) Structure-function relationship of the inhibition of the 3,5,3′-triiodothyronine binding to the alpha1- and beta1-thyroid hormone receptor by amiodarone analogs. Endocrinology 137:2807-2814.
-
(1996)
Endocrinology
, vol.137
, pp. 2807-2814
-
-
Van Beeren, H.C.1
Bakker, O.2
Wiersinga, W.M.3
-
58
-
-
0034703251
-
Desethylamiodarone interferes with the binding of co-activator GRIP-1 to the beta 1-thyroid hormone receptor
-
van Beeren HC, Bakker O, and Wiersinga WM (2000) Desethylamiodarone interferes with the binding of co-activator GRIP-1 to the beta 1-thyroid hormone receptor. FEBS Lett 481:213-216.
-
(2000)
FEBS Lett
, vol.481
, pp. 213-216
-
-
Van Beeren, H.C.1
Bakker, O.2
Wiersinga, W.M.3
-
59
-
-
0037320339
-
Dronerarone acts as a selective inhibitor of 3,5,3′- triiodothyronine binding to thyroid hormone receptor-alpha(1): In vitro and in vivo evidence
-
van Beeren HC, Jong WM, Kaptein E, Visser TJ, Bakker O, Wiersinga WM, Zandieh Doulabi B, Platvoet-ter Schiphorst M, Labruyere WT, Lamers WH, et al. (2003) Dronerarone acts as a selective inhibitor of 3,5,3′- triiodothyronine binding to thyroid hormone receptor-alpha(1): in vitro and in vivo evidence. Endocrinology 144:552-558.
-
(2003)
Endocrinology
, vol.144
, pp. 552-558
-
-
Van Beeren, H.C.1
Jong, W.M.2
Kaptein, E.3
Visser, T.J.4
Bakker, O.5
Wiersinga, W.M.6
Zandieh Doulabi, B.7
Platvoet-Ter Schiphorst, M.8
Labruyere, W.T.9
Lamers, W.H.10
-
60
-
-
0032511895
-
Activation of the thyroid hormone receptor alpha gene promoter by the orphan nuclear receptor ERR alpha
-
Vanacker JM, Bonnelye E, Delmarre C, and Laudet V (1998) Activation of the thyroid hormone receptor alpha gene promoter by the orphan nuclear receptor ERR alpha. Oncogene 17:2429-2435.
-
(1998)
Oncogene
, vol.17
, pp. 2429-2435
-
-
Vanacker, J.M.1
Bonnelye, E.2
Delmarre, C.3
Laudet, V.4
-
61
-
-
1642563956
-
Tissue-specific effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the activity of 5′-deiodinases I and II in rats
-
Viluksela M, Raasmaja A, Lebofsky M, Stahl BU, and Rozman KK (2004) Tissue-specific effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the activity of 5′-deiodinases I and II in rats. Toxicol Lett 147:133-142.
-
(2004)
Toxicol Lett
, vol.147
, pp. 133-142
-
-
Viluksela, M.1
Raasmaja, A.2
Lebofsky, M.3
Stahl, B.U.4
Rozman, K.K.5
-
62
-
-
17744379363
-
Hormone selectivity in thyroid hormone receptors
-
Wagner RL, Huber BR, Shiau AK, Kelly A, Cunha Lima ST, Scanlan TS, Apriletti JW, Baxter JD, West BL, and Fletterick RJ (2001) Hormone selectivity in thyroid hormone receptors. Mol Endocrinol 15:398-410.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 398-410
-
-
Wagner, R.L.1
Huber, B.R.2
Shiau, A.K.3
Kelly, A.4
Cunha Lima, S.T.5
Scanlan, T.S.6
Apriletti, J.W.7
Baxter, J.D.8
West, B.L.9
Fletterick, R.J.10
-
63
-
-
0022998995
-
The c-erb-A gene encodes a thyroid hormone receptor
-
Weinberger C, Thompson CC, Ong ES, Lebo R, Gruol DJ, and Evans RM (1986) The c-erb-A gene encodes a thyroid hormone receptor. Nature (Lond) 324:641-646.
-
(1986)
Nature (Lond)
, vol.324
, pp. 641-646
-
-
Weinberger, C.1
Thompson, C.C.2
Ong, E.S.3
Lebo, R.4
Gruol, D.J.5
Evans, R.M.6
-
65
-
-
0032518922
-
Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1
-
Wikstrom L, Johansson C, Salto C, Barlow C, Campos Barros A, Baas F, Forrest D, Thoren P, and Vennstrom B (1998) Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1. EMBO (Eur Mol Biol Organ) J 17:455-461.
-
(1998)
EMBO (Eur Mol Biol Organ) J
, vol.17
, pp. 455-461
-
-
Wikstrom, L.1
Johansson, C.2
Salto, C.3
Barlow, C.4
Campos Barros, A.5
Baas, F.6
Forrest, D.7
Thoren, P.8
Vennstrom, B.9
-
66
-
-
0033762445
-
Cloning and characterization of two novel thyroid hormone receptor beta isoforms
-
Williams GR (2000) Cloning and characterization of two novel thyroid hormone receptor beta isoforms. Mol Cell Biol 20:8329-8342.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8329-8342
-
-
Williams, G.R.1
-
67
-
-
0037828418
-
Thyroid hormone action: Insight from transgenic mouse models
-
Wondisford FE (2003) Thyroid hormone action: insight from transgenic mouse models. J Investig Med 51:215-220.
-
(2003)
J Investig Med
, vol.51
, pp. 215-220
-
-
Wondisford, F.E.1
-
68
-
-
0842308023
-
2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor
-
Yamada-Okabe T, Aono T, Sakai H, Kashima Y, and Yamada-Okabe H (2004) 2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor. Toxicol Appl Pharmacol 194:201-210.
-
(2004)
Toxicol Appl Pharmacol
, vol.194
, pp. 201-210
-
-
Yamada-Okabe, T.1
Aono, T.2
Sakai, H.3
Kashima, Y.4
Yamada-Okabe, H.5
-
69
-
-
0034964207
-
Physiological and molecular basis of thyroid hormone action
-
Yen PM (2001) Physiological and molecular basis of thyroid hormone action. Physiol Rev 81:1097-1142.
-
(2001)
Physiol Rev
, vol.81
, pp. 1097-1142
-
-
Yen, P.M.1
-
70
-
-
0042335979
-
Molecular basis of resistance to thyroid hormone
-
Yen PM (2003) Molecular basis of resistance to thyroid hormone. Trends Endocrinol Metab 14:327-333.
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 327-333
-
-
Yen, P.M.1
-
71
-
-
10744226856
-
Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice
-
Yen PM, Feng X, Flamant F, Chen Y, Walker RL, Weiss RE, Chassande O, Samarut J, Refetoff S, and Meltzer PS (2003) Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. EMBO Rep 4:581-587.
-
(2003)
EMBO Rep
, vol.4
, pp. 581-587
-
-
Yen, P.M.1
Feng, X.2
Flamant, F.3
Chen, Y.4
Walker, R.L.5
Weiss, R.E.6
Chassande, O.7
Samarut, J.8
Refetoff, S.9
Meltzer, P.S.10
-
72
-
-
0344859905
-
Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver
-
Zandieh-Doulabi B, Dop E, Schneiders M, Schiphorst MP, Mansen A, Vennstrom B, Dijkstra CD, Bakker O, and Wiersinga WM (2003) Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver. J Endocrinol 179:379-385.
-
(2003)
J Endocrinol
, vol.179
, pp. 379-385
-
-
Zandieh-Doulabi, B.1
Dop, E.2
Schneiders, M.3
Schiphorst, M.P.4
Mansen, A.5
Vennstrom, B.6
Dijkstra, C.D.7
Bakker, O.8
Wiersinga, W.M.9
-
73
-
-
12344333360
-
Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/neurogranin expression in the developing rat brain
-
Zoeller RT, Bansal R, and Parris C (2005) Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/neurogranin expression in the developing rat brain. Endocrinology 146:607-612.
-
(2005)
Endocrinology
, vol.146
, pp. 607-612
-
-
Zoeller, R.T.1
Bansal, R.2
Parris, C.3
-
74
-
-
0034465692
-
Developmental exposure to polychlorinated biphenyls exerts thyroid hormone-like effects on the expression of RC3/neurogranin and myelin basic protein messenger ribonucleic acids in the developing rat brain
-
Zoeller RT, Dowling AL, and Vas AA (2000) Developmental exposure to polychlorinated biphenyls exerts thyroid hormone-like effects on the expression of RC3/neurogranin and myelin basic protein messenger ribonucleic acids in the developing rat brain. Endocrinology 141:181-189.
-
(2000)
Endocrinology
, vol.141
, pp. 181-189
-
-
Zoeller, R.T.1
Dowling, A.L.2
Vas, A.A.3
-
75
-
-
0036072338
-
Thyroid hormone brain development and the environment
-
Zoeller TR, Dowling AL, Herzig CT, Iannacone EA, Gauger KJ, and Bansal R (2002) Thyroid hormone brain development and the environment. Environ Health Perspect 110 (Suppl 3):355-361.
-
(2002)
Environ Health Perspect
, vol.110
, Issue.SUPPL. 3
, pp. 355-361
-
-
Zoeller, T.R.1
Dowling, A.L.2
Herzig, C.T.3
Iannacone, E.A.4
Gauger, K.J.5
Bansal, R.6
|