Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3

EMBO Journal

Volumn 19, Issue 16, 2000, Pages 4342-4350

  Li, Jiwen ^a   Wang, Jin ^a   Wang, Jianxiang ^b   Nawaz, Zafar ^a   Liu, Johnson M ^b   Qin, Jun ^a   Wong, Jiemin ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

HDAC3; Repression; SMRT and N CoR corepressor complexes; TBL1

Indexed keywords

CELL EXTRACT; HISTONE DEACETYLASE; THYROID HORMONE RECEPTOR; TRANSDUCIN;

ANIMAL CELL; ARTICLE; CHROMATOGRAPHY; FEMALE; HELA CELL; IMMUNOAFFINITY CHROMATOGRAPHY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; XENOPUS;

ANIMALIA;

EID: 0034663815     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.16.4342     Document Type: Article

References (45)

1. Alland, L., Muhle, R., Hou, H., Jr, Potes, J., Chin, L., Schreiber-Agus, N. and DePinho, R.A. (1997) Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature, 387, 49-55.
2. Baniahmad, A., Steiner, C., Kohne, A.C. and Renkawitz, R. (1990) Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site. Cell, 61, 505-514.
3. Baniahmad, A., Leng, X., Burris, T.P., Tsai, S.Y., Tsai, M.J. and O'Malley, B.W. (1995) The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol. Cell. Biol., 15, 76-86.
4. Bassi, M.T. et al. (1999) X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats. Am. J. Hum. Genet., 64, 1604-1616.
5. Casanova, J. et al. (1994) Functional evidence for ligand-dependent dissociation of thyroid hormone and retinoic acid receptors from an inhibitory cellular factor. Mol. Cell. Biol., 14, 5756-5765.
6. Chen, J.D. and Evans, R.M. (1995) A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature, 377, 454-457.
7. Ciana, P., Braliou, G.G., Demay, F.G., von Lindern, M., Barettino, D., Beug, H. and Stunnenberg, H.G. (1998) Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo. EMBO J., 17, 7382-7394.
8. Dhordain, P., Lin, R.J., Quief, S., Lantoine, D., Kerckaert, J.P., Evans, R.M. and Albagli, O. (1998) The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. Nucleic Acids Res., 26, 4645-4651.
9. Dong, X., Tsuda, L., Zavitz, K.H., Lin, M., Li, S., Carthew, R.W. and Zipursky, S.L. (1999) ebi regulates epidermal growth factor receptor signaling pathways in Drosophila. Genes Dev., 13, 954-965.
10. Dressel, U., Thormeyer, D., Altincicek, B., Paululat, A., Eggert, M., Schneider, S., Tenbaum, S.P., Renkawitz, R. and Baniahmad, A. (1999) Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily. Mol. Cell. Biol., 19, 3383-3394.
11. Emiliani, S., Fischle, W., Van Lint, C., Al-Abed, Y. and Verdin, E. (1998) Characterization of a human RPD3 ortholog. HDAC3. Proc. Natl Acad. Sci. USA, 95, 2795-2800.
12. Forrest, D., Erway, L.C., Ng, L., Altschuler, R. and Curran, T. (1996) Thyroid hormone receptor β is essential for development of auditory function. Nature Genet., 13, 354-357.
13. Glass, C.K., Lipkin, S.M., Devary, O.V. and Rosenfeld, M.G. (1989) Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell. 59, 697-708.
14. Glass, C.K. and Rosenfeld, M.G. (2000) The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev., 14, 121-141.
15. Grozinger, C.M. Hassig, C.A. and Schreiber, S.L. (1999) Three proteins define a class of human histone deacetylases related to yeast Hda1p. Proc. Natl Acad. Sci. USA, 96, 4868-4873.
16. Gu, W. and Roeder, R.G. (1997) Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell, 90, 595-606.
17. Harlow, E. and Lane, D. (1988) Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
18. Hebbes, T.R., Thorne, A.W. and Crane-Robinson, C. (1988) A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J., 7, 1395-1402.
19. Heinzel, T. et al. (1997) A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature, 387, 43-48.
20. Hong, S.H., David, G., Wong, C.W., Dejean, A. and Privalsky, M.L. (1997) SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor α (RARα) and PLZF-RARα oncoproteins associated with acute promyelocytic leukemia. Proc. Natl Acad. Sci. USA, 94, 9028-9033.
21. Horlein, A.J. et al. (1995) Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature, 377, 397-404.
22. Huang, E.Y., Zhang, J., Miska, E.A., Guenther, M.G., Kouzarides, T. and Lazar, M.A. (2000) Nuclear receptor compressors partner with class II histone deacetylases in a Sin3-independent repression pathway. Genes Dev., 14, 45-54.
23. Kao, H.Y., Downes, M., Ordentlich, P., and Evans, R.M. (2000) Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev., 14, 55-66.
24. Kao, H.Y., Ordentlich, P., Koyano-Nakagawa, N., Tang, Z., Downes, M., Kintner, C.R., Evans, R.M. and Kadesch, T. (1998) A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev., 12, 2269-2277.
25. Kouzarides, T. (1999) Histone acetylases and deacetylases in cell proliferation. Curr. Opin. Genet. Dev., 9, 40-48.
26. Lee, D.Y., Hayes, J.J., Pruss, D. and Wolffe, A.P. (1993) A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell, 72, 73-84.
27. Li, J., O'Malley, B.W. and Wong, J. (2000) p300 requires its histone acetyltransferase activity and SRC-1 interaction domain to facilitate thyroid hormone receptor activation in chromatin. Mol. Cell. Biol., 20, 2031-2042.
28. McKenna, N.J., Lanz, R.B. and O'Malley, B.W. (1999) Nuclear receptor coregulators: cellular and molecular biology. Endocrinol. Rev., 20, 321-344.
29. Nagy, L., Kao, H.Y., Chakravarti, D., Lin, R.J., Hassig, C.A., Ayer, D.E., Schreiber, S.L. and Evans, R.M. (1997) Nuclear receptor repression mediated by a complex containing SMRT. mSin3A and histone deacetylase. Cell, 89, 373-380.
30. Nawaz, Z., Lonard, D.M., Smith, C.L., Lev-Lehman, E., Tsai, S.Y., Tsai, M.J. and O'Malley, B.W. (1999) The Angelman syndrome-associated protein. E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol. Cell. Biol., 19, 1182-1189.
31. Ordentlich, P., Downes, M., Xie, W., Genin, A., Spinner, N.B. and Evans, R.M. (1999) Unique forms of human and mouse nuclear receptor corepressor SMRT. Proc. Natl Acad. Sci. USA, 96, 2639-2644.
32. Park, E.J., Schroen, D.J., Yang, M., Li, H., Li, L. and Chen, J.D. (1999) SMRTe, a silencing mediator for retinoid and thyroid hormone receptors - extended isoform that is more related to the nuclear receptor corepressor. Proc. Natl Acad. Sci. USA, 96, 3519-3524.
33. Parthun, M.R., Widom, J. and Gottschling, D.E. (1996) The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism. Cell, 87, 85-94.
34. Qin, J., Fenyo, D., Zhao, Y., Hall, W.W., Chao, D.M., Wilson, C.J., Young, R.A. and Chait, B.T. (1997) A strategy for rapid, high-confidence protein identification. Anal. Chem., 69, 3995-4001.
35. Turner, B.M. and O'Neill, L.P. (1995) Histone acetylation in chromatin and chromosomes. Semin. Cell Biol., 6, 229-236.
36. Wang, J., Hoshino, T., Redner, R.L., Kajigaya, S. and Liu, J.M. (1998) ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex. Proc. Natl Acad. Sci. USA, 95, 10860-10865.
37. Wang, W. et al. (1996) Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J., 15, 5370-5382.
38. Wolffe, A.P. (1994) Transcription: in tune with the histones. Cell, 77, 13-16.
39. Wong, J., Patterton, D., Imhof, A., Guschin, D., Shi, Y.B. and Wolffe, A.P. (1998) Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase. EMBO J., 17, 520-534.
40. Wong, J., Shi, Y.B. and Wolffe, A.P. (1995) A role for nucleosome assembly in both silencing and activation of the Xenopus TRβ A gene by the thyroid hormone receptor. Genes Dev., 9, 2696-2711.
41. Xue, Y., Wong, J., Moreno, G.T., Young, M.K., Cote, J. and Wang, W. (1998) NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol. Cell, 2, 851-861.
42. Yang, W.M., Yao, Y.L., Sun, J.M., Davie, J.R. and Seto, E. (1997) Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. J. Biol. Chem., 272, 28001-28007.
43. Zamir, I., Harding, H.P., Atkins, G.B., Horlein, A., Glass, C.K., Rosenfeld, M.G. and Lazar, M.A. (1996) A nuclear hormone receptor corepressor mediates transcriptional silencing by receptors with distinct repression domains. Mol. Cell. Biol., 16, 5458-5465.
44. Zhang, J., Guenther, M.G., Carthew, R.W. and Lazar, M.A. (1998) Proteasomal regulation of nuclear receptor corepressor-mediated repression. Genes Dev., 12, 1775-1780.
45. Zhang, Y., Iratni, R., Erdjument-Bromage, H., Tempst, P. and Reinberg, D. (1997) Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex. Cell, 89, 357-364.