A Corepressor/Coactivator Exchange Complex Required for Transcriptional Activation by Nuclear Receptors and Other Regulated Transcription Factors

Cell

Volumn 116, Issue 4, 2004, Pages 511-526

  Perissi, Valentina ^a,b   Aggarwal, Aneel ^d   Glass, Christopher K ^c   Rose, David W ^a   Rosenfeld, Michael G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; NUCLEAR RECEPTOR COREPRESSOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEASOME; PROTEIN; PROTEIN SMRT; RECEPTOR PROTEIN; RECEPTOR SUBTYPE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSDUCIN; TRANSDUCIN BETA LIKE 1; TRANSDUCIN BETA LIKE 1 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; GENE ACTIVATION; GENE DELETION; GENE REPRESSION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEM CELL; TRANSCRIPTION INITIATION;

ANIMALIA; MAMMALIA;

EID: 1342264315     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(04)00133-3     Document Type: Article

References (71)

1. Amson R.B., Nemani M., Roperch J.P., Israeli D., Bougueleret L., Le Gall I., Medhioub M., Linares-Cruz G., Lethrosne F., Pasturaud P., et al. Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis. activation of the vertebrate homologue of the Drosophila seven in absentia gene Proc. Natl. Acad. Sci. USA. 93:1996;3953-3957.
2. Asahara H., Dutta S., Kao H.Y., Evans R.M., Montminy M. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Mol. Cell. Biol. 19:1999;8219-8225.
3. Bain G., Ray W.J., Yao M., Gottlieb D.I. Retinoic acid promotes neural and represses mesodermal gene expression in mouse embryonic stem cells in culture. Biochem. Biophys. Res. Commun. 223:1996;691-694.
4. Baek S.H., Ohgi K.A., Rose D.W., Koo E.H., Glass C.K., Rosenfeld M.G. Regulated exchange of N-CoR corepressor and Tip60 coactivator complexes links expression by NF-κB and β-amyloid precursor protein. Cell. 110:2002;55-67.
5. Bassi M.T., Ramesar R.S., Caciotti B., Winship I.M., De Grandi A., Riboni M., Townes P.L., Beighton P., Ballabio A., Borsani G. X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats. Am. J. Hum. Genet. 64:1999;1604-1616.
6. Boncinelli E., Simeone A., Acampora D., Mavilio F. HOX gene activation by retinoic acid. Trends Genet. 7:1991;329-334.
7. Boulton S.J., Brook A., Staehling-Hampton K., Heitzler P., Dyson N. A role for Ebi in neuronal cell cycle control. EMBO J. 19:2000;5376-5386.
8. Conaway R.C., Brower C.S., Conaway J.W. Emerging roles of ubiquitin in transcription regulation. Science. 296:2002;1254-1258.
9. Cosma M.P., Tanaka T., Nasmyth K. Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. Cell. 97:1999;299-311.
10. Dean M., Levine R.A., Campisi J. c-myc regulation during retinoic acid-induced differentiation of F9 cells is posttranscriptional and associated with growth arrest. Mol. Cell. Biol. 6:1986;518-524.
11. Delage-Mourroux R., Martini P.G., Choi I., Kraichely D.M., Hoeksema J., Katzenellenbogen B.S. Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA. J. Biol. Chem. 275:2000;35848-35856.
12. Dennis A.P., Haq R.U., Nawaz Z. Importance of the regulation of nuclear receptor degradation. Front. Biosci. 6:2001;D954-D959.
13. de The H., Marchio A., Tiollais P., Dejean A. Differential expression and ligand regulation of the retinoic acid receptor alpha and beta genes. EMBO J. 8:1989;429-433.
14. Dilworth F.J., Chambon P. Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription. Oncogene. 20:2001;3047-3054.
15. Disteche C.M., Dinulos M.B., Bassi M.T., Elliott R.W., Rugarli E.I. Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X chromosomes. Mamm. Genome. 9:1998;1062-1064.
16. Dong X., Tsuda L., Zavitz K.H., Lin M., Li S., Carthew R.W., Zipursky S.L. Ebi regulates epidermal growth factor receptor signaling pathways in Drosophila. Genes Dev. 13:1999;954-965.
17. Fernandes I., Bastien Y., Wai T., Nygard K., Lin R., Cormier O., Lee H.S., Eng F., Bertos N.R., Pelletier N., et al. Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms. Mol. Cell. 11:2003;139-150.
18. Fraichard A., Chassande O., Bilbaut G., Dehay C., Savatier P., Samarut J. In vitro differentiation of embryonic stem cells into glial cells and functional neurons. J. Cell Sci. 108:1995;3181-3188.
19. Gianni M., Bauer A., Garattini E., Chambon P., Rochette-Egly C. Phosphorylation by p38MAPK and recruitment of SUG-1 are required for RA-induced RAR gamma degradation and transactivation. EMBO J. 21:2002;3760-3769.
20. Glass C.K., Rosenfeld M.G. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14:2000;121-141.
21. Glickman M.H., Ciechanover A. The ubiquitin-proteasome proteolytic pathway. destruction for the sake of construction Physiol. Rev. 82:2002;373-428.
22. Grandori C., Cowley S.M., James L.P., Eisenman R.N. The Myc/Max/Mad network and the transcriptional control of cell behavior. Annu. Rev. Cell Dev. Biol. 16:2000;653-699.
23. Grimaldi P.A. The roles of PPARs in adipocyte differentiation. Prog. Lipid Res. 40:2001;269-281.
24. Guenther M.G., Lane W.S., Fischle W., Verdin E., Lazar M.A., Shiekhattar R. A core SMRT co-repressor complex containing HDAC3 and TBL1, a WD40-repreat protein linked to deafness. Genes Dev. 14:2000;1048-1057.
25. Heery D.M., Kalkhoven E., Hoare S., Parker M.G. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature. 387:1997;733-736.
26. Hermanson O., Jepsen K., Rosenfeld M.G. N-CoR controls differentiation of neural stem cells into astrocytes. Nature. 419:2002;934-939.
27. Hong S.H., Privalsky M.L. The SMRT corepressor is regulated by a MEK-1 kinase pathway. inhibition of corepressor function is associated with SMRT phosphorylation and nuclear export Mol. Cell Biol. 20:2000;6612-6625.
28. Hu X., Lazar M.A. The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature. 402:1999;93-96.
29. Jackson P.K., Eldridge A.G., Freed E., Furstenthal L., Hsu J.Y., Kaiser B.K., Reimann J.D. The lore of the RINGs. substrate recognition and catalysis by ubiquitin ligases Trends Cell Biol. 10:2000;429-439.
30. Jepsen K., Rosenfeld M.G. Biological roles and mechanistic actions of co-repressor complexes. J. Cell Sci. 115:2002;689-698.
31. Kang Z., Pirskanen A., Janne O.A., Palvimo J.J. Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex. J. Biol. Chem. 277:2002;48366-48371.
32. Kim S.Y., Herbst A., Tworkowski K.A., Salghetti S.E., Tansey W.P. Skp2 regulates Myc protein stability and activity. Mol. Cell. 11:2003;1177-1188.
33. Kipreos, E.T., and Pagano, M. (2000). The F-box protein family. Genome Biol. 1, Reviews 3002.
34. Langston A.W., Thompson J.R., Gudas L.J. Retinoic acid-responsive enhancers located 3′ of the Hox A and Hox B homeobox gene clusters. Functional analysis. J. Biol. Chem. 272:1997;2167-2175.
35. Levine M., Tjian R. Transcription regulation and animal diversity. Nature. 424:2003;147-151.
36. Li J., Wang J., Nawaz Z., Liu J.M., Qin J., Wong J. Both co-repressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J. 19:2000;4342-4350.
37. Li X., Perissi V., Liu F., Rose D.W., Rosenfeld M.G. Tissue-specific regulation of retinal and pituitary precursor cell proliferation. Science. 297:2002;1180-1183.
38. Lipford J.R., Deshaies R.J. Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation. Nat. Cell Biol. 5:2003;845-850.
39. Lin H.K., Altuwaijri S., Lin W.J., Kan P.Y., Collins L.L., Chang C. Proteasome activity is required for androgen receptor transcriptional activity via regulation of androgen receptor nuclear translocation and interaction with coregulators in prostate cancer cells. J. Biol. Chem. 277:2002;36570-36576.
40. Liu Y.Y., Tachiki K.H., Brent G.A. A targeted thyroid hormone receptor alpha gene dominant-negative mutation (P398H) selectively impairs gene expression in differentiated embryonic stem cells. Endocrinology. 143:2002;2664-2672.
41. Lonard D.M., Nawaz Z., Smith C.L., O'Malley B.W. The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation. Mol. Cell. 5:2000;939-948.
42. Mangelsdorf D.J., Thummel C., Beato M., Herrlich P., Schutz G., Umesono K., Blumberg B., Kastner P., Mark M., Chambon P., et al. The nuclear receptor superfamily. the second decade Cell. 83:1995;835-839.
43. Matsuzawa S.I., Reed J.C. Siah-1, SIP and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 response. Mol. Cell. 7:2001;915-926.
44. McInerney E.M., Rose D.W., Flynn S.E., Westin S., Mullen T.M., Krones A., Inostroza J., Torchia J., Nolte R.T., Assa-Munt N., et al. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 12:1998;3357-3368.
45. McKenna N.J., O'Malley B.W. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell. 108:2002;465-474.
46. McKinsey T.A., Zhang C.L., Olson E.N. Control of muscle development by dueling HATs and HDACs. Curr. Opin. Genet. Dev. 11:2001;497-504.
47. McNally J.G., Muller W.G., Walker D., Wolford R., Hager G.L. The glucocorticoid receptor. rapid exchange with regulatory sites in living cells Science. 287:2000;1262-1265.
48. Molinari E., Gilman M., Natesan S. Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in vivo. EMBO J. 18:1999;6439-6447.
49. Muratani M., Tansey W.P. How the ubiquitin-proteasome system controls transcription. Nat. Rev. Mol. Cell Biol. 4:2003;192-201.
50. Nagy L., Kao H.Y., Love J.D., Li C., Banayo E., Gooch J.T., Krishna V., Chatterjee K., Evans R.M., Schwabe J.W.R. Mechanism of corepressor binding and release from nuclear hormone receptors. Genes Dev. 13:1999;3209-3216.
51. Ntambi J.M., Young-Cheul K. Adipocyte differentiation and gene expression. J. Nutr. 130:2000;3122S-3126S.
52. Patton E.E., Willems A.R., Tyers M. Combinatorial control in ubiquitin-dependent proteolysis. don't Skp the F-box hypothesis Trends Genet. 14:1998;236-243.
53. Perissi V., Staszewski L.M., McInerney E.M., Kurokawa R., Krones A., Rose D.W., Lambert M.H., Milburn M.V., Glass C.K., Rosenfeld M.G. Molecular determinants of nuclear receptor-corepressor interaction. Genes Dev. 13:1999;3198-3208.
54. Reid G., Hubner M.R., Metivier R., Brand H., Denger S., Manu D., Beaudouin J., Ellenberg J., Gannon F. Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling. Mol. Cell. 11:2003;695-707.
55. Rosen E.D., Walkey C.J., Puigserver P., Spiegelman B.M. Transcriptional regulation of adipogenesis. Genes Dev. 14:2000;1293-1307.
56. Salghetti S.E., Muratani M., Wijnen H., Futcher B., Tansey W.P. Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis. Proc. Natl. Acad. Sci. USA. 97:2000;3118-3123.
57. Sasik R., Calvo E., Corbeil J. Statistical analysis of high-density oligonucleotide arrays. a multiplicative noise model Bioinformatics. 18:2002;1633-1640.
58. Shang Y., Hu X., DiRenzo J., Lazar M.A., Brown M. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell. 103:2000;843-852.
59. Shang Y., Myers M., Brown M. Formation of the androgen receptor transcription complex. Mol. Cell. 9:2002;601-610.
60. Strubing C., Ahnert-Hilger G., Shan J., Wiedenmann B., Hescheler J., Wobus A.M. Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons. Mech. Dev. 53:1995;275-287.
61. Torchia J., Rose D.W., Inostroza J., Kamei Y., Westin S., Glass C.K., Rosenfeld M.G. The transcriptional coactivator, p/CIP, binds CBP and mediates nuclear-receptor function. Nature. 387:1997;677-684.
62. Tsuda L., Nagaraj R., Zipursky S.L., Banerjee U. An EGFR/Ebi/Sno pathway promotes delta expression by inactivating Su(H)/SMRTER repression during inductive notch signaling. Cell. 110:2002;625-637.
63. Von der Lehr N., Johansson S., Wu S., Bahram F., Castell A., Cetinkaya C., Hydbring P., Weidung I., Nakayama K., Nakayama K.I., et al. The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. Mol. Cell. 11:2003;1189-1200.
64. Weiss J.W., Orkin S.H. In vitro differentiation of murine embryonic stem cells. new approaches to old problems J. Clin. Invest. 97:1996;591-595.
65. Wu G., Xu G., Schulman B.A., Jeffrey P.D., Harper J.W., Pavletich N.P. Structure of a beta-TrCP1-Skp1-beta-catenin complex. destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase Mol. Cell. 11:2003;1445-1456.
66. Xu L., Lavinsky R.M., Dasen J.S., Flynn S.E., McInerney E.M., Mullen T.M., Heinzel T., Szeto D., Korzus E., Kurokawa R., et al. Signal-specific co-activator domain requirements for Pit-1 activation. Nature. 395:1998;301-306.
67. Xu H.E., Stanley T.B., Montana V.G., Lambert M.H., Shearer B.G., Cobb J.E., McKee D.D., Galardi C.M., Plunket K.D., Nolte R.T., et al. Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. Nature. 415:2002;813-817.
68. Yan F., Gao X., Lonard D.M., Nawaz Z. Specific ubiquitin-conjugating enzymes promote degradation of specific nuclear receptor coactivators. Mol. Endocrinol. 17:2003;1315-1331.
69. Yoon H.G., Chan D.W., Huang Z.Q., Li J., Fondell J.D., Qin J., Wong J. Purification and functional characterization of the human N-CoR complex. the roles of HDAC3, TBL1 and TBLR1 EMBO J. 22:2003;1336-1346.
70. Zhang J., Guenther M.G., Carthew R.W., Lazar M.A. Proteosomal regulation of nuclear receptor corepressor-mediated repression. Genes Dev. 12:1998;1775-1780.
71. Zhang J., Kalkum M., Chait B.T., Roeder R.G. The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol. Cell. 9:2002;611-623.