Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis

PLoS ONE

Volumn 5, Issue 9, 2010, Pages

  Lahnalampi, Mari ^a   Heinäniemi, Merja ^b   Sinkkonen, Lasse ^b   Wabitsch, Martin ^c   Carlberg, Carsten ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF LUXEMBOURG   (Luxembourg)

^c UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FARNESOID X RECEPTOR; LIVER RECEPTOR HOMOLOG 1; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; ONCOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PREGNANE X RECEPTOR; RETINOID ORPHAN RECEPTOR ALPHA; RETINOID ORPHAN RECEPTOR BETA; RETINOID X RECEPTOR; RETINOID X RECEPTOR ALPHA; RETINOID X RECEPTOR BETA; UNCLASSIFIED DRUG; CELL RECEPTOR;

ADIPOCYTE; ADIPOGENESIS; ARTICLE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; TRANSCRIPTION INITIATION SITE; UPREGULATION; ANIMAL; CELL LINE; CELL STRAIN 3T3; CYTOLOGY; GENETICS; METABOLISM; MOUSE; MULTIGENE FAMILY;

3T3 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; CELL DIFFERENTIATION; CELL LINE; GENE EXPRESSION PROFILING; HUMANS; MICE; MULTIGENE FAMILY; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 77958571302     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012991     Document Type: Article

References (53)

1. Rosen ED, Spiegelman BM (2006) Adipocytes as regulators of energy balance and glucose homeostasis. Nature 444: 847-853.
2. Farmer SR (2006) Transcriptional control of adipocyte formation. Cell Metab 4: 263-273.
3. Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, et al. (1999) PPARc is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 4: 611-617.
4. Nielsen R, Pedersen TA, Hagenbeek D, Moulos P, Siersbaek R, et al. (2008) Genome-wide profiling of PPARc:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev 22: 2953-2967.
5. Lefterova MI, Zhang Y, Steger DJ, Schupp M, Schug J, et al. (2008) PPARc and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genomewide scale. Genes Dev 22: 2941-2952.
6. Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ (2001) Nuclear receptors and lipid physiology: opening the X-files. Science 294: 1866-1870.
7. Nuclear-Receptor-Committee (1999) A unified nomenclature system for the nuclear receptor superfamily. Cell 97: 161-163.
8. Diamant M, Heine RJ (2003) Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence. Drugs 63: 1373-1405.
9. Maglich JM, Sluder A, Guan X, Shi Y, McKee DD, et al. (2001) Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Genome Biol 2: R29.
10. Bertrand S, Brunet FG, Escriva H, Parmentier G, Laudet V, et al. (2004) Evolutionary genomics of nuclear receptors: from twenty-five ancestral genes to derived endocrine systems. Mol Biol Evol 21: 1923-1937.
11. Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, et al. (2006) Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 126: 789-799.
12. Mohan R, Heyman RA (2003) Orphan nuclear receptor modulators. Curr Top Med Chem 3: 1637-1647.
13. Burris TP (2008) Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock. Mol Endocrinol 22: 1509-1520.
14. Nettles KW, Greene GL (2005) Ligand control of coregulator recruitment to nuclear receptors. Annu Rev Physiol 67: 309-333.
15. Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, et al. (2006) International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol Rev 58: 798-836.
16. Wabitsch M, Brenner RE, Melzner I, Braun M, Moller P, et al. (2001) Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord 25: 8-15.
17. Fischer-Posovszky P, Newell FS, Wabitsch M, Tornqvist HE (2008) Human SGBS Cells - a Unique Tool for Studies of Human Fat Cell Biology. Obes Facts 1: 184-189.
18. Green H, Kehinde O (1975) An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 5: 19-27.
19. Hummasti S, Laffitte BA, Watson MA, Galardi C, Chao LC, et al. (2004) Liver X receptors are regulators of adipocyte gene expression but not differentiation: identification of apoD as a direct target. J Lipid Res 45: 616-625.
20. Fu M, Sun T, Bookout AL, Downes M, Yu RT, et al. (2005) A Nuclear Receptor Atlas: 3T3-L1 adipogenesis. Mol Endocrinol 19: 2437-2450.
21. Fumoto T, Yamaguchi T, Hirose F, Osumi T (2007) Orphan nuclear receptor Nur77 accelerates the initial phase of adipocyte differentiation in 3T3-L1 cells by promoting mitotic clonal expansion. J Biochem 141: 181-192.
22. Chao LC, Bensinger SJ, Villanueva CJ, Wroblewski K, Tontonoz P (2008) Inhibition of adipocyte differentiation by Nur77, Nurr1, and Nor1. Mol Endocrinol 22: 2596-2608.
23. Tchkonia T, Lenburg M, Thomou T, Giorgadze N, Frampton G, et al. (2007) Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns. Am J Physiol Endocrinol Metab 292: E298-307.
24. Cidlowski JA, Cidlowski NB (1981) Regulation of glucocorticoid receptors by glucocorticoids in cultured HeLa S3 cells. Endocrinology 109: 1975-1982.
25. Schlechte JA, Ginsberg BH, Sherman BM (1982) Regulation of the glucocorticoid receptor in human lymphocytes. J Steroid Biochem 16: 69-74.
26. Steger DJ, Grant GR, Schupp M, Tomaru T, Lefterova MI, et al. (2010) Propagation of adipogenic signals through an epigenomic transition state. Genes Dev 24: 1035-1044.
27. Floyd ZE, Stephens JM (2003) STAT5A promotes adipogenesis in nonprecursor cells and associates with the glucocorticoid receptor during adipocyte differentiation. Diabetes 52: 308-314.
28. Brentani MM, Wajchenberg BL, Cesar FP, Martins VR (1986) Regulation of the glucocorticoid receptor by glucocorticoids in human mononuclear leukocytes. Horm Res 24: 9-17.
29. Alon U (2007) Network motifs: theory and experimental approaches. Nat Rev Genet 8: 450-461.
30. Reddy TE, Pauli F, Sprouse RO, Neff NF, Newberry KM, et al. (2009) Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. Genome Res 19: 2163-2171.
31. Xue JC, Schwarz EJ, Chawla A, Lazar MA (1996) Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARc. Mol Cell Biol 16: 1567-1575.
32. Kong J, Li YC (2006) Molecular mechanism of 1,25-dihydroxyvitamin D3 inhibition of adipogenesis in 3T3-L1 cells. Am J Physiol Endocrinol Metab 290: E916-924.
33. Berry DC, Noy N (2009) All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/ delta and retinoic acid receptor. Mol Cell Biol 29: 3286-3296.
34. Matsusue K, Peters JM, Gonzalez FJ (2004) PPARbeta/delta potentiates PPARgamma-stimulated adipocyte differentiation. Faseb J 18: 1477-1479.
35. Fontaine C, Dubois G, Duguay Y, Helledie T, Vu-Dac N, et al. (2003) The orphan nuclear receptor Rev-Erba is a peroxisome proliferator-activated receptor (PPAR) c target gene and promotes PPARc -induced adipocyte differentiation. J Biol Chem 278: 37672-37680.
36. Wang J, Lazar MA (2008) Bifunctional role of Rev-erbalpha in adipocyte differentiation. Mol Cell Biol 28: 2213-2220.
37. Dunlap JC (1999) Molecular bases for circadian clocks. Cell 96: 271-290.
38. Ueda HR, Chen W, Adachi A, Wakamatsu H, Hayashi S, et al. (2002) A transcription factor response element for gene expression during circadian night. Nature 418: 534-539.
39. Cermakian N, Boivin DB (2009) The regulation of central and peripheral circadian clocks in humans. Obes Rev 10 (Suppl 2): 25-36.
40. O'Neill JS, Maywood ES, Chesham JE, Takahashi JS, Hastings MH (2008) cAMP-dependent signaling as a core component of the mammalian circadian pacemaker. Science 320: 949-953.
41. Yang X, Downes M, Yu RT, Bookout AL, He W, et al. (2006) Nuclear receptor expression links the circadian clock to metabolism. Cell 126: 801-810.
42. Zvonic S, Ptitsyn AA, Conrad SA, Scott LK, Floyd ZE, et al. (2006) Characterization of peripheral circadian clocks in adipose tissues. Diabetes 55: 962-970.
43. Beaven SW, Tontonoz P (2006) Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia. Annu Rev Med 57: 313-329.
44. Blouin K, Veilleux A, Luu-The V, Tchernof A (2009) Androgen metabolism in adipose tissue: recent advances. Mol Cell Endocrinol 301: 97-103.
45. Mishra A, Zhu XG, Ge K, Cheng SY (2010) Adipogenesis is differentially impaired by thyroid hormone receptor mutant isoforms. J Mol Endocrinol 44: 247-255.
46. Elgadi A, Zemack H, Marcus C, Norgren S (2010) Tissue-specific knockout of TSHr in white adipose tissue increases adipocyte size and decreases TSHinduced lipolysis. Biochem Biophys Res Commun 393: 526-530.
47. Pantoja C, Huff JT, Yamamoto KR (2008) Glucocorticoid signaling defines a novel commitment state during adipogenesis in vitro. Mol Biol Cell 19: 4032-4041.
48. Pratt WB, Toft DO (1997) Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr Rev 18: 306-360.
49. Dong Y, Poellinger L, Gustafsson JA, Okret S (1988) Regulation of glucocorticoid receptor expression: evidence for transcriptional and posttranslational mechanisms. Mol Endocrinol 2: 1256-1264.
50. Rosewicz S, McDonald AR, Maddux BA, Goldfine ID, Miesfeld RL, et al. (1988) Mechanism of glucocorticoid receptor down-regulation by glucocorticoids. J Biol Chem 263: 2581-2584.
51. Vedeckis WV, Ali M, Allen HR (1989) Regulation of glucocorticoid receptor protein and mRNA levels. Cancer Res 49: 2295s-2302s.
52. Lee TI, Rinaldi NJ, Robert F, Odom DT, Bar-Joseph Z, et al. (2002) Transcriptional regulatory networks in Saccharomyces cerevisiae. Science 298: 799-804.
53. Rosenfeld N, Elowitz MB, Alon U (2002) Negative autoregulation speeds the response times of transcription networks. J Mol Biol 323: 785-793.