Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 8, 2011, Pages 3412-3417

  Fang, Sungsoon ^a   Suh, Jae Myoung ^a   Atkins, Annette R ^a   Hong, Suk Hyun ^a   Leblanc, Mathias ^a   Nofsinger, Russell R ^a   Yu, Ruth T ^a   Downes, Michael ^a   Evans, Ronald M ^a,b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Chronic inflammation; Metabolic syndrome; Transcriptional repression

Indexed keywords

ADIPONECTIN; CHOLESTEROL; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; BODY COMPOSITION; BROWN ADIPOSE TISSUE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENERGY EXPENDITURE; ENVIRONMENTAL STRESS; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; HYPERTROPHY; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; LIPID DIET; LIPID STORAGE; LIVER; LIVER FUNCTION; METABOLIC DISORDER; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN TARGETING; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; ANIMALS; DIET; HOMEOSTASIS; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; MICE; NUCLEAR RECEPTOR CO-REPRESSOR 2; OBESITY; OXIDATIVE PHOSPHORYLATION;

MUS;

EID: 79952775519     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1017707108     Document Type: Article

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