Gut memories: Towards a cognitive neurobiology of irritable bowel syndrome

Neuroscience and Biobehavioral Reviews

Volumn 36, Issue 1, 2012, Pages 310-340

  Kennedy, Paul J ^a,b   Clarke, Gerard ^a,b   Quigley, Eamonn M M ^a,b   Groeger, John A ^b   Dinan, Timothy G ^a,b   Cryan, John F ^a,b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Brain gut axis; Central nervous system; Cognition; FMRI; IBS; Immune activity; Irritable bowel syndrome; Menstrual cycle; Microbiota; Mood disorder; Neurobiology; Neuropsychological; Pain; PET; Sleep disturbance; Stress

Indexed keywords

ANTIDEPRESSANT AGENT; GLUCOCORTICOID; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; NORADRENALIN; SEX HORMONE; TUMOR NECROSIS FACTOR ALPHA;

ADRENAL DISEASE; ANALGESIA; ANXIETY; BRAIN FUNCTION; CATASTROPHIZING; CENTRAL NERVOUS SYSTEM FUNCTION; CHRONIC PAIN; CLINICAL EFFECTIVENESS; COGNITIVE DEFECT; COGNITIVE THERAPY; DEPRESSION; DISEASE ACTIVITY; DISEASE COURSE; EMOTIONAL MEMORY; EMOTIONALITY; EPISODIC MEMORY; HUMAN; HYPNOSIS; HYPOPHYSIS DISEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; ILLNESS BEHAVIOR; IMMUNOSTIMULATION; INTESTINE FLORA; INTESTINE INNERVATION; IRRITABLE COLON; LIFE STRESS; MEMORY; MENSTRUAL CYCLE; MENTAL STRESS; MOOD DISORDER; NEUROBIOLOGY; NEUROIMAGING; NEUROMODULATION; NEUROPSYCHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PLACEBO EFFECT; PRIORITY JOURNAL; REVIEW; SLEEP DISORDER; SOMATIZATION; VISCERAL PAIN; WORKING MEMORY;

COGNITION DISORDERS; GASTROINTESTINAL TRACT; HUMANS; IRRITABLE BOWEL SYNDROME; MODELS, BIOLOGICAL; NEUROBIOLOGY; NEUROIMAGING; STRESS, PSYCHOLOGICAL;

EID: 82855178769     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2011.07.001     Document Type: Review

References (529)

1. Aaron L.A., Buchwald D. A review of the evidence for overlap among unexplained clinical conditions. Ann. Intern. Med. 2001, 134:868-881.
2. Adeyemi E.O., Desai K.D., Towsey M., Ghista D. Characterization of autonomic dysfunction in patients with irritable bowel syndrome by means of heart rate variability studies. Am. J. Gastroenterol. 1999, 94:816-823.
3. Adeyemo M.A., Spiegel B.M., Chang L. Meta-analysis: do irritable bowel syndrome symptoms vary between men and women?. Aliment. Pharmacol. Ther. 2010, 32:738-755.
4. Afzal M., Potokar J.P., Probert C.S., Munafo M.R. Selective processing of gastrointestinal symptom-related stimuli in irritable bowel syndrome. Psychosom. Med. 2006, 68:758-761.
5. Aisa B., Tordera R., Lasheras B., Del Rio J., Ramirez M.J. Cognitive impairment associated to HPA axis hyperactivity after maternal separation in rats. Psychoneuroendocrinology 2007, 32:256-266.
6. Aisa B., Tordera R., Lasheras B., Del Rio J., Ramirez M.J. Effects of maternal separation on hypothalamic-pituitary-adrenal responses, cognition and vulnerability to stress in adult female rats. Neuroscience 2008, 154:1218-1226.
7. Al-Khatib K., Lin H.C. Immune activation and gut microbes in irritable bowel syndrome. Gut Liver 2009, 3:14-19.
8. Alley D.E., Crimmins E.M., Karlamangla A., Hu P., Seeman T.E. Inflammation and rate of cognitive change in high-functioning older adults. J. Gerontol. A Biol. Sci. Med. Sci. 2008, 63:50-55.
9. Aloe L., Fiore M., Probert L., Turrini P., Tirassa P. Overexpression of tumour necrosis factor alpha in the brain of transgenic mice differentially alters nerve growth factor levels and choline acetyltransferase activity. Cytokine 1999, 11:45-54.
10. Altamura M., Goldberg T.E., Elvevag B., Holroyd T., Carver F.W., Weinberger D.R., Coppola R. Prefrontal cortex modulation during anticipation of working memory demands as revealed by magnetoencephalography. Int. J. Biomed. Imaging 2010, 840416. 10.1155/2010/840416.
11. Altman G., Cain K.C., Motzer S., Jarrett M., Burr R., Heitkemper M. Increased symptoms in female IBS patients with dysmenorrhea and PMS. Gastroenterol. Nurs. 2006, 29:4-11.
12. Alvarez J.A., Emory E. Executive function and the frontal lobes: a meta-analytic review. Neuropsychol. Rev. 2006, 16:17-42.
13. Anisman H., Zaharia M.D., Meaney M.J., Merali Z. Do early-life events permanently alter behavioral and hormonal responses to stressors?. Int. J. Dev. Neurosci. 1998, 16:149-164.
14. Arnold M.C., Papanicolaou D.A., O'Grady J.A., Lotsikas A., Dale J.K., Straus S.E., Grafman J. Using an interleukin-6 challenge to evaluate neuropsychological performance in chronic fatigue syndrome. Psychol. Med. 2002, 32:1075-1089.
15. Austin M.P., Mitchell P., Goodwin G.M. Cognitive deficits in depression: possible implications for functional neuropathology. Br. J. Psychiatry 2001, 178:200-206.
16. Azpiroz F., Camilleri M., Mayer E.A., Poitras P., Serra J., Spiller R.C. Mechanisms of hypersensitivity in IBS and functional disorders. Neurogastroenterol. Motil. 2007, 19:62-88.
17. Backhed F., Ley R.E., Sonnenburg J.L., Peterson D.A., Gordon J.I. Host-bacterial mutualism in the human intestine. Science 2005, 307:1915-1920.
18. Baier P.C., May U., Scheller J., Rose-John S., Schiffelholz T. Impaired hippocampus-dependent and -independent learning in IL-6 deficient mice. Behav. Brain Res. 2009, 200:192-196.
19. Balschun D., Wetzel W., Del Rey A., Pitossi F., Schneider H., Zuschratter W., Besedovsky H.O. Interleukin-6: a cytokine to forget. FASEB J. 2004, 18:1788-1790.
20. Banich M.T., Mackiewicz K.L., Depue B.E., Whitmer A.J., Miller G.A., Heller W. Cognitive control mechanisms, emotion and memory: a neural perspective with implications for psychopathology. Neurosci. Biobehav. Rev. 2009, 33:613-630.
21. Bantick S., Wise R., Ploghaus A., Clare S., Smith S., Tracey I. Imaging how attention modulates pain in humans using functional MRI. Brain Behav. Immun. 2002, 125:310-319.
22. Baran S.E., Armstrong C.E., Niren D.C., Hanna J.J., Conrad C.D. Chronic stress and sex differences on the recall of fear conditioning and extinction. Neurobiol. Learn. Mem. 2009, 91:323-332.
23. Barnett J.H., Robbins T.W., Leeson V.C., Sahakian B.J., Joyce E.M., Blackwell A.D. Assessing cognitive function in clinical trials of schizophrenia. Neurosci. Biobehav. Rev. 2010, 34:1161-1177.
24. Barrientos R.M., Higgins E.A., Sprunger D.B., Watkins L.R., Rudy J.W., Maier S.F. Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus. Behav. Brain Res. 2002, 134:291-298.
25. Baune B., Ponath G., Golledge J., Varga G., Arolt V., Rothermundt M., Berger K. Association between IL-8 cytokine and cognitive performance in an elderly general population-the MEMO-study. Neurobiol. Aging 2008, 29:937-944.
26. Beck A.T. Thinking and depression. I. Idiosyncratic content and cognitive distortions. Arch. Gen. Psychiatry 1963, 9:324-333.
27. Beck A.T. Thinking and depression. II. Theory and therapy. Arch. Gen. Psychiatry 1964, 10:561-571.
28. Beck A.T. Cognitive models of depression. J. Cogn. Psychother. 1987, 1:5-37.
29. Beck A.T. The current state of cognitive therapy: a 40-year retrospective. Arch. Gen. Psychiatry 2005, 62:953-959.
30. Beck A.T. The evolution of the cognitive model of depression and its neurobiological correlates. Am. J. Psychiatry 2008, 165:969-977.
31. Bellani R., Luecken L., Conrad C. Peripubertal anxiety profile can predict predisposition to spatial memory impairments following chronic stress. Behav. Brain Res. 2006, 166:263-270.
32. Benedetti F. The opposite effects of the opiate antagonist naloxone and the cholecystokinin antagonist proglumide on placebo analgesia. Pain 1996, 64:535-543.
33. Benedetti F., Amanzio M. The neurobiology of placebo analgesia: from endogenous opioids to cholecystokinin. Prog. Neurobiol. 1997, 52:109-125.
34. Benedetti F., Amanzio M., Maggi G. Potentiation of placebo analgesia by proglumide. Lancet 1995, 346:1231.
35. Berman S.M., Chang L., Suyenobu B., Derbyshire S.W., Stains J., Fitzgerald L., Mandelkern M., Hamm L., Vogt B., Naliboff B.D., Mayer E.A. Condition-specific deactivation of brain regions by 5-HT3 receptor antagonist Alosetron. Gastroenterology 2002, 123:969-977.
36. Berman S., Munakata J., Naliboff B.D., Chang L., Mandelkern M., Silverman D., Kovalik E., Mayer E.A. Gender differences in regional brain response to visceral pressure in IBS patients. Eur. J. Pain 2000, 4:157-172.
37. Berman S.M., Naliboff B.D., Suyenobu B., Labus J.S., Stains J., Ohning G., Kilpatrick L., Bueller J.A., Ruby K., Jarcho J., Mayer E.A. Reduced brainstem inhibition during anticipated pelvic visceral pain correlates with enhanced brain response to the visceral stimulus in women with irritable bowel syndrome. J. Neurosci. 2008, 28:349-359.
38. Bingel U., Lorenz J., Schoell E., Weiller C., Buchel C. Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network. Pain 2006, 120:8-15.
39. Birnbaum S., Gobeske K.T., Auerbach J., Taylor J.R., Arnsten A.F. A role for norepinephrine in stress-induced cognitive deficits: alpha-1-adrenoceptor mediation in the prefrontal cortex. Biol. Psychiatry 1999, 46:1266-1274.
40. Bjugstad K.B., Flitter W.D., Garland W.A., Su G.C., Arendash G.W. Preventive actions of a synthetic antioxidant in a novel animal model of AIDS dementia. Brain Res. 1998, 795:349-357.
41. Blanchard E.B. A critical review of cognitive, behavioral, and cognitive-behavioral therapies for irritable bowel syndrome. J. Cogn. Psychother. 2005, 19:101-123.
42. Blanchard E.B., Lackner J.M., Sanders K., Krasner S., Keefer L., Payne A., Gudleski G.D., Katz L., Rowell D., Sykes M., Kuhn E., Gusmano R., Carosella A.M., Firth R., Dulgar-Tulloch L. A controlled evaluation of group cognitive therapy in the treatment of irritable bowel syndrome. Behav. Res. Ther. 2007, 45:633-648.
43. Bohmelt A.H., Nater U.M., Franke S., Hellhammer D.H., Ehlert U. Basal and stimulated hypothalamic-pituitary-adrenal axis activity in patients with functional gastrointestinal disorders and healthy controls. Psychosom. Med. 2005, 67:288-294.
44. Bondi C., Rodriguez G., Gould G., Frazer A., Morilak D. Chronic unpredictable stress induces a cognitive deficit and anxiety-like behavior in rats that is prevented by chronic antidepressant drug treatment. Neuropsychopharmacology 2008, 33:320-331.
45. Borkowska A., Drozdz W., Jurkowski P., Rybakowski J.K. The Wisconsin Card Sorting Test and the N-back test in mild cognitive impairment and elderly depression. World J. Biol. Psychiatry 2009, 10:870-876.
46. Bos K.J., Fox N., Zeanah C.H., Nelson Iii C.A. Effects of early psychosocial deprivation on the development of memory and executive function. Front. Behav. Neurosci. 2009, 3:16.
47. Bouin M., Plourde V., Boivin M., Riberdy M., Lupien F., Laganiere M., Verrier P., Poitras P. Rectal distention testing in patients with irritable bowel syndrome: sensitivity, specificity, and predictive values of pain sensory thresholds. Gastroenterology 2002, 122:1771-1777.
48. Bourdeau I., Bard C., Noel B., Leclerc I., Cordeau M.P., Belair M., Lesage J., Lafontaine L., Lacroix A. Loss of brain volume in endogenous Cushing's syndrome and its reversibility after correction of hypercortisolism. J. Clin. Endocrinol. Metab. 2002, 87:1949-1954.
49. Bowie C.R., Leung W.W., Reichenberg A., McClure M.M., Patterson T.L., Heaton R.K., Harvey P.D. Predicting schizophrenia patients' real-world behavior with specific neuropsychological and functional capacity measures. Biol. Psychiatry 2008, 63:505-511.
50. Bowman R.E., Zrull M.C., Luine V.N. Chronic restraint stress enhances radial arm maze performance in female rats. Brain Res. 2001, 904:279-289.
51. Braida D., Sacerdote P., Panerai A.E., Bianchi M., Aloisi A.M., Iosue S., Sala M. Cognitive function in young and adult IL (interleukin)-6 deficient mice. Behav. Brain Res. 2004, 153:423-429.
52. Bravo J.A., Dinan T.G., Cryan J.F. Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders. Int. J. Neuropsychopharmacol. 2011, 14:666-683.
53. Bravo, J.A., Scaravage, E., Chew, M., Forsythe, P., Dinan, T.G., Bienenstock, J., Cryan, J.F., 2010. The probiotic Lactobacillus reuteri induces constitutive changes in central GABA receptor expression. SFN 795.17/FFF2 (abstract).
54. Bremner J.D., Vythilingam M., Vermetten E., Southwick S.M., McGlashan T., Staib L.H., Soufer R., Charney D.S. Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse. Biol. Psychiatry 2003, 53:879-889.
55. Brennan F.X., Beck K.D., Servatius R.J. Proinflammatory cytokines differentially affect leverpress avoidance acquisition in rats. Behav. Brain Res. 2004, 153:351-355.
56. Brooks J.C., Nurmikko T.J., Bimson W.E., Singh K.D., Roberts N. fMRI of thermal pain: effects of stimulus laterality and attention. Neuroimage 2002, 15:293-301.
57. Buchanan T.W., Lovallo W.R. Enhanced memory for emotional material following stress-level cortisol treatment in humans. Psychoneuroendocrinology 2001, 26:307-317.
58. Buckner R.L., Wheeler M.E. The cognitive neuroscience of remembering. Nat. Rev. Neurosci. 2001, 2:624-634.
59. Burke H.M., Davis M.C., Otte C., Mohr D.C. Depression and cortisol responses to psychological stress: a meta-analysis. Psychoneuroendocrinology 2005, 30:846-856.
60. Burr R.L., Jarrett M.E., Cain K.C., Jun S.E., Heitkemper M.M. Catecholamine and cortisol levels during sleep in women with irritable bowel syndrome. Neurogastroenterol. Motil. 2009, 21. 1148-e97.
61. Bush G., Vogt B.A., Holmes J., Dale A.M., Greve D., Jenike M.A., Rosen B.R. Dorsal anterior cingulate cortex: a role in reward-based decision making. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:523-528.
62. Bushnell M., Duncan G., Hofbauer R., Ha B., Chen J., Carrier B. Pain perception: is there a role for primary somatosensory cortex?. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:7705-7709.
63. Cahill L. Why sex matters for neuroscience. Nat. Rev. 2006, 7:477-484.
64. Cahill L., Gorski L., Le K. Enhanced human memory consolidation with post-learning stress: interaction with the degree of arousal at encoding. Learn. Mem. 2003, 10:270-274.
65. Cahill L., Haier R.J., Fallon J., Alkire M.T., Tang C., Keator D., Wu J., McGaugh J.L. Amygdala activity at encoding correlated with long-term, free recall of emotional information. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:8016-8021.
66. Camilleri M. Management of the irritable bowel syndrome. Gastroenterology 2001, 120:652-668.
67. Capuron L., Fornwalt F.B., Knight B.T., Harvey P.D., Ninan P.T., Miller A.H. Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals?. J. Affect. Disord. 2009, 119:181-185.
68. Casement M.D., Broussard J.L., Mullington J.M., Press D.Z. The contribution of sleep to improvements in working memory scanning speed: a study of prolonged sleep restriction. Biol. Psychol. 2006, 72:208-212.
69. Cebra J.J. Influences of microbiota on intestinal immune system development. Am. J. Clin. Nutr. 1999, 69:1046S-1051S.
70. Cerqueira J., Mailliet F., Almeida O., Jay T., Sousa N. The prefrontal cortex as a key target of the maladaptive response to stress. J. Neurosci. 2007, 27:2781-2787.
71. Cerqueira J.J., Pego J.M., Taipa R., Bessa J.M., Almeida O.F., Sousa N. Morphological correlates of corticosteroid-induced changes in prefrontal cortex-dependent behaviors. J. Neurosci. 2005, 25:7792-7800.
72. Chadwick V.S., Chen W.X., Shu D.R., Paulus B., Bethwaite P., Tie A., Wilson I. Activation of the mucosal immune system in irritable bowel syndrome. Gastroenterology 2002, 122:1778-1783.
73. Chan R.C., Shum D., Toulopoulou T., Chen E.Y. Assessment of executive functions: review of instruments and identification of critical issues. Arch. Clin. Neuropsychol. 2008, 23:201-216.
74. Chang L., Heitkemper M.M. Gender differences in irritable bowel syndrome. Gastroenterology 2002, 123:1686-1701.
75. Chang L., Lee O.Y., Naliboff B., Schmulson M., Mayer E.A. Sensation of bloating and visible abdominal distension in patients with irritable bowel syndrome. Am. J. Gastroenterol. 2001, 96:3341-3347.
76. Chang L., Sundaresh S., Elliott J., Anton P.A., Baldi P., Licudine A., Mayer M., Vuong T., Hirano M., Naliboff B.D., Ameen V.Z., Mayer E.A. Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in irritable bowel syndrome. Neurogastroenterol. Motil. 2009, 21:149-159.
77. Chapman S., Martin M. Attention to pain words in irritable bowel syndrome: increased orienting and speeded engagement. Br. J. Health Psychol. 2011, 16:47-60.
78. Chen J., Buchanan J.B., Sparkman N.L., Godbout J.P., Freund G.G., Johnson R.W. Neuroinflammation and disruption in working memory in aged mice after acute stimulation of the peripheral innate immune system. Brain Behav. Immun. 2008, 22:301-311.
79. Chitkara D.K., van Tilburg M.A.L., Blois-Martin N., Whitehead W.E. Early life risk factors that contribute to irritable bowel syndrome in adults: a systematic review. Am. J. Gastroenterol. 2008, 103:765-774.
80. Christodoulou C., DeLuca J., Lange G., Johnson S.K., Sisto S.A., Korn L., Natelson B.H. Relation between neuropsychological impairment and functional disability in patients with chronic fatigue syndrome. J. Neurol. Neurosurg. Psychiatry 1998, 64:431-434.
81. Chrousos G.P. Stress and disorders of the stress system. Nat. Rev. Endocrinol. 2009, 5:374-381.
82. Chuah L.Y., Chee M.W. Functional neuroimaging of sleep deprived healthy volunteers and persons with sleep disorders: a brief review. Ann. Acad. Med. Singapore 2008, 37:689-694.
83. Chuah Y.M.L., Venkatraman V., Dinges D.F., Chee M.W. The neural basis of interindividual variability in inhibitory efficiency after sleep deprivation. J. Neurosci. 2006, 26:7156-7162.
84. Chudasama Y., Robbins T.W. Functions of frontostriatal systems in cognition: comparative neuropsychopharmacological studies in rats, monkeys and humans. Biol. Psychol. 2006, 73:19-38.
85. Clark D.A., Beck A.T. Cognitive theory and therapy of anxiety and depression: convergence with neurobiological findings. Trends Cogn. Sci. 2010, 14:418-424.
86. Clarke G., Fitzgerald P., Cryan J.F., Cassidy E.M., Quigley E.M., Dinan T.G. Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterol. 2009, 9:6.
87. Clarke G., Fitzgerald P., Hennessy A.A., Cassidy E.M., Quigley E.M., Ross P., Stanton C., Cryan J.F., Dinan T.G. Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome. J. Lipid Res. 2010, 51:1186-1192.
88. Clarke G., O'Mahony S.M., Hennessy A.A., Ross P., Stanton C., Cryan J.F., Dinan T.G. Chain reactions: early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood. Behav. Brain Res. 2009, 205:319-321.
89. Clarke G., Quigley E.M.M., Cryan J.F., Dinan T.G. Irritable bowel syndrome: towards biomarker identification. Trends Mol. Med. 2009, 15:478-489.
90. Codling C., O'Mahony L., Shanahan F., Quigley E.M., Marchesi J.R. A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome. Dig. Dis. Sci. 2010, 55:392-397.
91. Cohen O., Reichenberg A., Perry C., Ginzberg D., Pollmacher T., Soreq H., Yirmiya R. Endotoxin-induced changes in human working and declarative memory associate with cleavage of plasma " readthrough" acetylcholinesterase. J. Mol. Neurosci. 2003, 21:199-212.
92. Collins S.M. A case for an immunological basis for irritable bowel syndrome. Gastroenterology 2002, 122:2078-2080.
93. Collins S.M., Bercik P. The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease. Gastroenterology 2009, 136:2003-2014.
94. Colvert E., Rutter M., Kreppner J., Beckett C., Castle J., Groothues C., Hawkins A., Stevens S., Sonuga-Barke E.J. Do theory of mind and executive function deficits underlie the adverse outcomes associated with profound early deprivation?: findings from the English and Romanian adoptees study. J. Abnorm. Child Psychol. 2008, 36:1057-1068.
95. Colzato L.S., Hertsig G., van den Wildenberg W.P., Hommel B. Estrogen modulates inhibitory control in healthy human females: evidence from the stop-signal paradigm. Neuroscience 2010, 167:709-715.
96. Compton R.J., Banich M.T., Mohanty A., Milham M.P., Herrington J., Miller G.A., Scalf P.E., Webb A., Heller W. Paying attention to emotion: an fMRI investigation of cognitive and emotional stroop tasks. Cogn. Affect. Behav. Neurosci. 2003, 3:81-96.
97. Conners C.K., Staff M. Conners' Continuous Performance Test II: Computer Program for Windows Technical Guide and Software Manual 2000, Mutli-Health Systems, North Tonwanda, NY.
98. Conrad C., Galea L., Kuroda Y., McEwen B. Chronic stress impairs rat spatial memory on the Y maze, and this effect is blocked by tianeptine pretreatment. Behav. Neurosci. 1996, 110:1321-1334.
99. Conrad C.D., LeDoux J.E., Magarinos A.M., McEwen B.S. Repeated restraint stress facilitates fear conditioning independently of causing hippocampal CA3 dendritic atrophy. Behav. Neurosci. 1999, 113:902-913.
100. Coogan A.N., O'Neill L.A., O'Connor J.J. The P38 mitogen-activated protein kinase inhibitor SB203580 antagonizes the inhibitory effects of interleukin-1beta on long-term potentiation in the rat dentate gyrus in vitro. Neuroscience 1999, 93:57-69.
101. Cordero M.I., Venero C., Kruyt N.D., Sandi C. Prior exposure to a single stress session facilitates subsequent contextual fear conditioning in rats - evidence for a role of corticosterone. Horm. Behav. 2003, 44:338-345.
102. Corney R.H., Stanton R. Physical Symptom severity, psychological and social dysfunction in a series of outpatients with irritable bowel syndrome. J. Psychosom. Res. 1990, 34:483-491.
103. Cosgrove K.P., Mazure C.M., Staley J.K. Evolving knowledge of sex differences in brain structure, function, and chemistry. Biol. Psychiatry 2007, 62:847-855.
104. Coull J.T., Frith C.D., Frackowiak R.S.J., Grasby P.M. A fronto-parietal network for rapid visual information processing: a PET study of sustained attention and working memory. Neuropsychologia 1996, 34:1085-1095.
105. Craig M.C., Murphy D.G. Oestrogen, cognition and the maturing female brain. J. Neuroendocrinol. 2007, 19:1-6.
106. Crombez G., Eccleston C., Baeyens F., Eelen P. The disruptive nature of pain: an experimental investigation. Behav. Res. Ther. 1996, 34:911-918.
107. Cryan, J.F., Clarke, G., Grenham, S., Scully, P., Shanahan, F., Dinan, T.G., 2010. The gut microbiome markedly influences hippocampal neurotransmission in the mouse: role of gender. SFN 795.18/FFF3 (abstract).
108. Cryan J.F., Holmes A. The ascent of mouse: advances in modelling human depression and anxiety. Nat. Rev. Drug Discov. 2005, 4:775-790.
109. Cryan J.F., O'Mahony S.M. The microbiome-gut-brain axis: from bowel to behavior. Neurogastroenterol. Motil. 2011, 23:187-192.
110. Cumberland P., Sethi D., Roderick P.J., Wheeler J.G., Cowden J.M., Roberts J.A., Rodrigues L.C., Hudson M.J., Tompkins D.S. The infectious intestinal disease study of England: a prospective evaluation of symptoms and health care use after an acute episode. Epidemiol. Infect. 2003, 130:453-460.
111. Cunningham A.J., Murray C.A., O'Neill L.A., Lynch M.A., O'Connor J.J. Interleukin-1 beta (IL-1 beta) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro. Neurosci. Lett. 1996, 203:17-20.
112. Dachir S., Kadar T., Robinzon B., Levy A. Cognitive deficits induced in young rats by long-term corticosterone administration. Behav. Neural Biol. 1993, 60:103-109.
113. Dancey C.P., Attree E.A., Stuart G., Wilson C., Sonnet A. Words fail me: the verbal IQ deficit in inflammatory bowel disease and irritable bowel syndrome. Inflamm. Bowel Dis. 2009, 15:852-857.
114. Dantzer R. Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity. Eur. J. Pharmacol. 2004, 500:399-411.
115. Dantzer R. Cytokine, sickness behavior, and depression. Immunol. Allergy Clin. North Am. 2009, 29:247-264.
116. Dantzer R., Wollman E.E., Yirmiya R. Cytokines, Stress, and Depression 1999, Plenum, Kluwer Academic, New York.
117. De Bellis M.D., Hooper S.R., Woolley D.P., Shenk C.E. Demographic, maltreatment, and neurobiological correlates of PTSD symptoms in children and adolescents. J. Pediatr. Psychol. 2010, 35:570-577.
118. de Jongh R., Geyer M.A., Olivier B., Groenink L. The effects of sex and neonatal maternal separation on fear-potentiated and light-enhanced startle. Behav. Brain Res. 2005, 161:190-196.
119. de Kloet E.R., Oitzl M.S., Joels M. Stress and cognition: are corticosteroids good or bad guys?. Trends Neurosci. 1999, 22:422-426.
120. de Quervain D.J., Henke K., Aerni A., Treyer V., McGaugh J.L., Berthold T., Nitsch R.M., Buck A., Roozendaal B., Hock C. Glucocorticoid-induced impairment of declarative memory retrieval is associated with reduced blood flow in the medial temporal lobe. Eur. J. Neurosci. 2003, 17:1296-1302.
121. de Quervain D.J., Roozendaal B., Nitsch R.M., McGaugh J.L., Hock C. Acute cortisone administration impairs retrieval of long-term declarative memory in humans. Nat. Neurosci. 2000, 3:313-314.
122. De Weerd P. Attention, neural basis of. Encyclopedia of cognitive science 2003, 408-414. Nature Publishing Group, London. L. Nadel (Ed.).
123. Dedovic K., Duchesne A., Andrews J., Engert V., Pruessner J.C. The brain and the stress axis: the neural correlates of cortisol regulation in response to stress. Neuroimage 2009, 47:864-871.
124. Dedovic K., Renwick R., Mahani N.K., Engert V., Lupien S.J., Pruessner J.C. The Montreal Imaging Stress Task: using functional imaging to investigate the effects of perceiving and processing psychosocial stress in the human brain. J. Psychiatry Neurosci. 2005, 30:319-325.
125. Delis D.C., Kramer J.H., Kaplan E., Ober B.A. California Verbal Learning Test 2000, The Psychological Corporation, San Antonio, TX. Second Edition, Adult Version ed.
126. Dere E., Easton A., Nadel L., Huston P.J. Handbook of Episodic Memory 2008, Elsevier, Amsterdam. 1st ed.
127. Desbonnet L., Garrett L., Clarke G., Bienenstock J., Dinan T.G. The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat. J. Psychiatr. Res. 2008, 43:164-174.
128. Diamond D.M., Bennett M.C., Fleshner M., Rose G.M. Inverted-U relationship between the level of peripheral corticosterone and the magnitude of hippocampal primed burst potentiation. Hippocampus 1992, 2:421-430.
129. Dick B., Eccleston C., Crombez G. Attentional functioning in fibromyalgia, rheumatoid arthritis, and musculoskeletal pain patients. Arthritis Rheum. 2002, 47:639-644.
130. Dick B.D., Rashiq S. Disruption of attention and working memory traces in individuals with chronic pain. Anesth. Analg. 2007, 104:1223-1229. (tables of contents).
131. Dickerson B.C., Eichenbaum H. The episodic memory system: neurocircuitry and disorders. Neuropsychopharmacology 2010, 35:86-104.
132. Dik M.G., Jonker C., Hack C.E., Smit J.H., Comijs H.C., Eikelenboom P. Serum inflammatory proteins and cognitive decline in older persons. Neurology 2005, 64:1371-1377.
133. Dinan T.G., Clarke G., Quigley E.M., Scott L.V., Shanahan F., Cryan J., Cooney J., Keeling P.W. Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors. Am. J. Gastroenterol. 2008, 103:2570-2576.
134. Dinan T.G., Cryan J., Shanahan F., Keeling P.W., Quigley E.M. IBS: an epigenetic perspective. Nat. Rev. Gastroenterol. Hepatol. 2010, 7:465-471.
135. Dinan T.G., Quigley E.M., Ahmed S.M., Scully P., O'Brien S., O'Mahony L., O'Mahony S., Shanahan F., Keeling P.W. Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker?. Gastroenterology 2006, 130:304-311.
136. Domes G., Heinrichs M., Rimmele U., Reichwald U., Hautzinger M. Acute stress impairs recognition for positive words-association with stress-induced cortisol secretion. Stress Int. J. Biol. Stress 2004, 7:173-181.
137. Domes G., Rothfischer J., Reichwald U., Hautzinger M. Inverted-U function between salivary cortisol and retrieval of verbal memory after hydrocortisone treatment. Behav. Neurosci. 2005, 119:512-517.
138. Drossman D.A. Review article: an integrated approach to the irritable bowel syndrome. Aliment. Pharmacol. Ther. 1999, 13(Suppl. 2):3-14.
139. Drossman D.A. The functional gastrointestinal disorders and the Rome III process. Gastroenterology 2006, 130:1377-1390.
140. Drossman D.A. Abuse, trauma, and GI illness: is there a link?. Am. J. Gastroenterol. 2011, 106:14-25.
141. Drossman D.A., Camilleri M., Mayer E.A., Whitehead W.E. AGA technical review on irritable bowel syndrome. Gastroenterology 2002, 123:2108-2131.
142. Drossman D.A., Leserman J., Li Z., Keefe F., Hu Y.J., Toomey T.C. Effects of coping on health outcome among women with gastrointestinal disorders. Psychosom. Med. 2000, 62:309-317.
143. Drossman D.A., McKee D.C., Sandler R.S., Mitchell C.M., Cramer E.M., Lowman B.C., Burger A.L. Psychosocial factors in the irritable bowel syndrome. A multivariate study of patients and nonpatients with irritable bowel syndrome. Gastroenterology 1988, 95:701-708.
144. Drossman D.A., Toner B.B., Whitehead W.E., Diamant N.E., Dalton C.B., Duncan S., Emmott S., Proffitt V., Akman D., Frusciante K., Le T., Meyer K., Bradshaw B., Mikula K., Morris C.B., Blackman C.J., Hu Y., Jia H., Li J.Z., Koch G.G., Bangdiwala S.I. Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders. Gastroenterology 2003, 125:19-31.
145. Dunlop S.P., Jenkins D., Neal K.R., Spiller R.C. Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS. Gastroenterology 2003, 125:1651-1659.
146. Earnst K.S., Virginia G., Wadley T.M., Steenwky A.B., Hammond A.E., Harrell L.E., Marson D.C. Loss of financial capacity in Alzheimer's disease: the role of working memory. Aging Neuropsychol. Cogn. 2001, 8:109-119.
147. Elliott R., Baker S.C., Rogers R.D., O'Leary D.A., Paykel E.S., Frith C.D., Dolan R.J., Sahakian B.J. Prefrontal dysfunction in depressed patients performing a complex planning task: a study using positron emission tomography. Psychol. Med. 1997, 27:937-942.
148. Elsenbruch S. Abdominal pain in irritable bowel syndrome: a review of putative psychological, neural and neuro-immune mechanisms. Brain Behav. Immun. 2011, 25:386-394.
149. Elsenbruch S., Holtmann G., Oezcan D., Lysson A., Janssen O., Goebel M.U., Schedlowski M. Are there alterations of neuroendocrine and cellular immune responses to nutrients in women with irritable bowel syndrome?. Am. J. Gastroenterol. 2004, 99:703-710.
150. Elsenbruch S., Rosenberger C., Bingel U., Forsting M., Schedlowski M., Gizewski E.R. Patients with irritable bowel syndrome have altered emotional modulation of neural responses to visceral stimuli. Gastroenterology 2010, 139:1310-1319.
151. Elsenbruch S., Rosenberger C., Enck P., Forsting M., Schedlowski M., Gizewski E.R. Affective disturbances modulate the neural processing of visceral pain stimuli in irritable bowel syndrome: an fMRI study. Gut 2010, 59:489-495.
152. Elzinga B.M., Roelofs K. Cortisol-induced impairments of working memory require acute sympathetic activation. Behav. Neurosci. 2005, 119:98-103.
153. Endo Y., Nishimura J.I., Kimura F. Impairment of maze learning in rats following long-term glucocorticoid treatments. Neurosci. Lett. 1996, 203:199-202.
154. Eriksson E.M., Andren K.I., Eriksson H.T., Kurlberg G.K. Irritable bowel syndrome subtypes differ in body awareness, psychological symptoms and biochemical stress markers. World J. Gastroenterol. 2008, 14:4889-4896.
155. Fass R., Fullerton S., Tung S., et al. Sleep disturbances in clinic patients with functional bowel disorders. Am. J. Gastroenterol. 2000, 95:195-200.
156. Faymonville M.E., Laureys S., Degueldre C., DelFiore G., Luxen A., Franck G., Lamy M., Maquet P. Neural mechanisms of antinociceptive effects of hypnosis. Anesthesiology 2000, 92:1257-1267.
157. Fernandez G., Klaver P., Fell J., Grunwald T., Elger C.E. Human declarative memory formation: segregating rhinal and hippocampal contributions. Hippocampus 2002, 12:514-519.
158. Fernandez G., Weis S., Stoffel-Wagner B., Tendolkar I., Reuber M., Beyenburg S., Klaver P., Fell J., de Greiff A., Ruhlmann J., Reul J., Elger C.E. Menstrual cycle-dependent neural plasticity in the adult human brain is hormone, task, and region specific. J. Neurosci. 2003, 23:3790-3795.
159. Ferry B., Roozendaal B., McGaugh J.L. Involvement of alpha1-adrenoceptors in the basolateral amygdala in modulation of memory storage. Eur. J. Pharmacol. 1999, 372:9-16.
160. Fiore M., Probert L., Kollias G., Akassoglou K., Alleva E., Aloe L. Neurobehavioral alterations in developing transgenic mice expressing TNF-alpha in the brain. Brain Behav. Immun. 1996, 10:126-138.
161. FitzGerald L.Z., Kehoe P., Sinha K. Hypothalamic-pituitary-adrenal axis dysregulation in women with irritable bowel syndrome in response to acute physical stress. West. J. Nurs. Res. 2009, 31:818-836.
162. Forbes A., MacAuley S., Chiotakakou-Faliakou E. Hypnotherapy and therapeutic audiotape: effective in previously unsuccessfully treated irritable bowel syndrome?. Int. J. Colorectal Dis. 2000, 15:328-334.
163. Forsythe P., Sudo N., Dinan T., Taylor V.H., Bienenstock J. Mood and gut feelings. Brain Behav. Immun. 2010, 24:9-16.
164. Frankenstein U., Richter W., McIntyre M., Rémy F. Distraction modulates anterior cingulate gyrus activations during the cold pressor test. Neuroimage 2001, 14:827-836.
165. Frankola K.A., Flora A.L., Torres A.K., Grissom E.M., Overstreet S., Dohanich G.P. Effects of early rearing conditions on cognitive performance in prepubescent male and female rats. Neurobiol. Learn. Mem. 2010, 94:91-99.
166. Franowicz J.S., Kessler L., Morgan C., Arnsten A.F.T. The alpha 2 noradrenergic agonist guanifacine improves spatial working memory in wild type mice with point mutations of the gene for the alpha-2A receptor. Soc. Soc. Neurosci. Abs. 1998, 24:711.
167. Fukudo S., Nomura T., Hongo M. Impact of corticotropin-releasing hormone on gastrointestinal motility and adrenocorticotropic hormone in normal controls and patients with irritable bowel syndrome. Gut 1998, 42:845-849.
168. Fuster J.M. The prefrontal cortex-an update: time is of the essence. Neuron 2001, 30:319-333.
169. Galvez R., Mesches M.H., McGaugh J.L. Norepinephrine release in the amygdala in response to footshock stimulation. Neurobiol. Learn. Mem. 1996, 66:253-257.
170. Gareau M.G., Wine E., Rodrigues D.M., Cho J.H., Whary M.T., Philpott D.J., Macqueen G., Sherman P.M. Bacterial infection causes stress-induced memory dysfunction in mice. Gut 2011, 60:307-317.
171. Gerber J., Bottcher T., Hahn M., Siemer A., Bunkowski S., Nau R. Increased mortality and spatial memory deficits in TNF-alpha-deficient mice in ceftriaxone-treated experimental pneumococcal meningitis. Neurobiol. Dis. 2004, 16:133-138.
172. Gianaros P.J., Derbyshire S.W., May J.C., Siegle G.J., Gamalo M.A., Jennings J.R. Anterior cingulate activity correlates with blood pressure during stress. Psychophysiology 2005, 42:627-635.
173. Gianaros P.J., Jennings J.R., Sheu L.K., Derbyshire S.W., Matthews K.A. Heightened functional neural activation to psychological stress covaries with exaggerated blood pressure reactivity. Hypertension 2007, 49:134-140.
174. Gibbs-Gallagher N., Palsson O.S., Levy R.L., Meyer K., Drossman D.A., Whitehead W.E. Selective recall of gastrointestinal-sensation words: evidence for a cognitive-behavioral contribution to irritable bowel syndrome. Am. J. Gastroenterol. 2001, 96:1133-1138.
175. Gibertini M. IL1 beta impairs relational but not procedural rodent learning in a water maze task. Adv. Exp. Med. Biol. 1996, 402:207-217.
176. Gibney S.M., Gosselin R.D., Dinan T.G., Cryan J.F. Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome. Neuroscience 2010, 165:675-683.
177. Gimeno D., Marmot M.G., Singh-Manoux A. Inflammatory markers and cognitive function in middle-aged adults: the Whitehall II study. Psychoneuroendocrinology 2008, 33:1322-1334.
178. Golan H., Levav T., Mendelsohn A., Huleihel M. Involvement of tumor necrosis factor alpha in hippocampal development and function. Cereb. Cortex 2004, 14:97-105.
179. Goldsmith G., Levin J.S. Effect of sleep quality on symptoms of irritable bowel syndrome. Dig. Dis. Sci. 1993, 38:1809-1814.
180. Gonsalkorale W.M., Houghton L.A., Whorwell P.J. Hypnotherapy in irritable bowel syndrome: a large-scale audit of a clinical service with examination of factors influencing responsiveness. Am. J. Gastroenterol. 2002, 97:954-961.
181. Gonsalkorale W.M., Miller V., Afzal A., Whorwell P.J. Long term benefits of hypnotherapy for irritable bowel syndrome. Gut 2003, 52:1623-1629.
182. Gonsalkorale W.M., Toner B.B., Whorwell P.J. Cognitive change in patients undergoing hypnotherapy for irritable bowel syndrome. J. Psychosom. Res. 2004, 56:271-278.
183. Gosselin R.D., O'Connor R.M., Tramullas M., Julio-Pieper M., Dinan T.G., Cryan J.F. Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms. Gastroenterology 2010, 138:2418-2425.
184. Grace G.M., Nielson W.R., Hopkins M., Berg M.A. Concentration and memory deficits in patients with fibromyalgia syndrome. J. Clin. Exp. Neuropsychol. 1999, 21:477-487.
185. Greve K.W., Love J.M., Sherwin E., Mathias C.W., Ramzinski P., Levy J. Wisconsin Card Sorting Test in chronic severe traumatic brain injury: factor structure and performance subgroups. Brain Inj. 2002, 16:29-40.
186. Grevert P., Albert L.H., Goldstein A. Partial antagonism of placebo analgesia by naloxone. Pain 1983, 16:129-143.
187. Groeger J.A., Field D., Hammond S.M. Measuring memory span. Int. J. Psychol. 1999, 34:359-363.
188. Groeger J.A., Viola A.U., Lo J.C., von Schantz M., Archer S.N., Dijk D.J. Early morning executive functioning during sleep deprivation is compromised by a PERIOD3 polymorphism. Sleep 2008, 31:1159-1167.
189. Guglielmetti S., Mora D., Gschwender M., Popp K. Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life -- a double-blind, placebo-controlled study. Alimentary Pharmacology & Therapeutics 2011, 33:1123-1132.
190. Gwee K.A., Leong Y.L., Graham C., McKendrick M.W., Collins S.M., Walters S.J., Underwood J.E., Read N.W. The role of psychological and biological factors in postinfective gut dysfunction. Gut 1999, 44:400-406.
191. Hamann S., Mao H. Positive and negative emotional verbal stimuli elicit activity in the left amygdala. Neuroreport 2002, 13:15-19.
192. Hampson E. Estrogen-related variations in human spatial and articulatory-motor skills. Psychoneuroendocrinology 1990, 15:97-111.
193. Harrison Y., Horne J.A., Rothwell A. Prefrontal neuropsychological effects of sleep deprivation in young adults - a model of healthy aging?. Sleep 2000, 23:1067-1073.
194. Harman K., Ruyak P. Working through the pain: a controlled study of the impact of persistent pain on performing a computer task. Clin. J. Pain 2005, 21:216-222.
195. Hart B.L. Biological basis of the behavior of sick animals. Neurosci. Biobehav. Rev. 1988, 12:123-137.
196. Hatta T., Nagaya K. Menstrual cycle phase effects on memory and Stroop task performance. Arch. Sex. Behav. 2009, 38:821-827.
197. Hazlett-Stevens H., Craske M.G., Mayer E.A., Chang L., Naliboff B.D. Prevalence of irritable bowel syndrome among university students: the roles of worry, neuroticism, anxiety sensitivity and visceral anxiety. J. Psychosom. Res. 2003, 55:501-505.
198. Hedges D.W., Woon F.L. Early-life stress and cognitive outcome. Psychopharmacology (Berl.) 2011, 214:121-130.
199. Heijtz R.D., Wang S., Anuar F., Qian Y., Bjorkholm B., Samuelsson A., Hibberd M.L., Forssberg H., Pettersson S. Normal gut microbiota modulates brain development and behavior. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:3047-3052.
200. Heitkemper M.M., Cain K.C., Jarrett M.E., Burr R.L., Hertig V., Bond E.F. Symptoms across the menstrual cycle in women with irritable bowel syndrome. Am. J. Gastroenterol. 2003, 98:420-430.
201. Heitkemper M.M., Chang L. Do fluctuations in ovarian hormones affect gastrointestinal symptoms in women with irritable bowel syndrome?. Gender medicine 2009, 6(Suppl. 2):152-167.
202. Het S., Ramlow G., Wolf O.T. A meta-analytic review of the effects of acute cortisol administration on human memory. Psychoneuroendocrinology 2005, 30:771-784.
203. Heyser C.J., Masliah E., Samimi A., Campbell I.L., Gold L.H. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:1500-1505.
204. Hillila M.T., Farkkila M.A. Prevalence of irritable bowel syndrome according to different diagnostic criteria in a non-selected adult population. Aliment. Pharmacol. Ther. 2004, 20:339-345.
205. Hofmann S.G., Smits J.A., Asnaani A., Gutner C.A., Otto M.W. Cognitive enhancers for anxiety disorders. Pharmacol Biochem Behav 2011, 99:275-284.
206. Holmes A., Wellman C.L. Stress-induced prefrontal reorganization and executive dysfunction in rodents. Neurosci. Biobehav. Rev. 2009, 33:773-783.
207. Houghton L.A., Heyman D.J., Whorwell P.J. Symptomatology, quality of life and economic features of irritable bowel syndrome-the effect of hypnotherapy. Aliment. Pharmacol. Ther. 1996, 10:91-95.
208. Houghton L.A., Whorwell P.J. Opening the doors of perception in the irritable bowel syndrome. Gut 1997, 41:567-568.
209. Hryniewicz A., Bialuk I., Kaminski K.A., Winnicka M.M. Impairment of recognition memory in interleukin-6 knock-out mice. Eur. J. Pharmacol. 2007, 577:219-220.
210. Hsu F.C., Garside M.J., Massey A.E., McAllister-Williams R.H. Effects of a single dose of cortisol on the neural correlates of episodic memory and error processing in healthy volunteers. Psychopharmacology (Berl.) 2003, 167:431-442.
211. Hu W.H., Wong W.M., Lam C.L., Lam K.F., Hui W.M., Lai K.C., Xia H.X., Lam S.K., Wong B.C. Anxiety but not depression determines health care-seeking behaviour in Chinese patients with dyspepsia and irritable bowel syndrome: a population-based study. Aliment. Pharmacol. Ther. 2002, 16:2081-2088.
212. Hui G.K., Figueroa I.R., Poytress B.S., Roozendaal B., McGaugh J.L., Weinberger N.M. Memory enhancement of classical fear conditioning by post-training injections of corticosterone in rats. Neurobiol. Learn. Mem. 2004, 81:67-74.
213. Hunt M.G., Milonova M., Moshier S. Catastrophizing the consequences of gastrointestinal symptoms in irritable bowel syndrome. J. Cogn. Psychother. 2009, 23:160-173.
214. Huot R.L., Plotsky P.M., Lenox R.H., McNamara R.K. Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats. Brain Res. 2002, 950:52-63.
215. Hyland N.P., Julio-Pieper M., O'Mahony S.M., Bulmer D.C., Lee K., Quigley E.M., Dinan T.G., Cryan J.F. A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?. Gut 2009, 58:1029-1030. (author reply 1030-1021).
216. Janitzkya K., Schweglerb H., Kröberb A., Roskodenb T., Yanagawac Y., Linkeb R. Species-relevant inescapable stress differently influences memory consolidation and retrieval of mice in a spatial radial arm maze. Behav. Brain Res. 2011, 219:142-148.
217. Jarrett M., Heitkemper M., Cain K., Burr R., Hertig V. Sleep disturbance influences gastrointestinal symptoms in women with irritable bowel syndrome. Dig. Dis. Sci. 2000, 45:952-959.
218. Johnson S.C., Saykin A.J., Flashman L.A., McAllister T.W., Sparling M.B. Brain activation on fMRI and verbal memory ability: functional neuroanatomic correlates of CVLT performance. J. Int. Neuropsychol. Soc. 2001, 7:55-62.
219. Jones M.P., Dilley J.B., Drossman D., Crowell M.D. Brain-gut connections in functional GI disorders: anatomic and physiologic relationships. Neurogastroenterol. Motil. 2006, 18:91-103.
220. Jordanova V., Stewart R., Davies E., Sherwood R., Prince M. Markers of inflammation and cognitive decline in an African-Caribbean population. Int. J. Geriatr. Psychiatry 2007, 22:966-973.
221. Kalisch R., Wiech K., Critchley H.D., Seymour B., O'Doherty J.P., Oakley D.A., Allen P., Dolan R.J. Anxiety reduction through detachment: subjective, physiological, and neural effects. J. Cogn. Neurosci. 2005, 17:874-883.
222. Kalisch R., Wiech K., Herrmann K., Dolan R.J. Neural correlates of self-distraction from anxiety and a process model of cognitive emotion regulation. J. Cogn. Neurosci. 2006, 18:1266-1276.
223. Kalman J., Juhasz A., Laird G., Dickens P., Jardanhazy T., Rimanoczy A., Boncz I., Parry-Jones W.L., Janka Z. Serum interleukin-6 levels correlate with the severity of dementia in Down syndrome and in Alzheimer's disease. Acta Neurol. Scand. 1997, 96:236-240.
224. Kamiya T., Wang L., Forsythe P., Goettsche G., Mao Y., Wang Y., Tougas G., Bienenstock J. Inhibitory effects of Lactobacillus reuteri on visceral pain induced by colorectal distension in Sprague-Dawley rats. Gut 2006, 55:191-196.
225. Kanazawa M., Palsson O.S., Thiwan S.I., Turner M.J., van Tilburg M.A., Gangarosa L.M., Chitkara D.K., Fukudo S., Drossman D.A., Whitehead W.E. Contributions of pain sensitivity and colonic motility to IBS symptom severity and predominant bowel habits. Am. J. Gastroenterol. 2008, 103:2550-2561.
226. Kane S.V., Sable K., Hanauer S.B. The menstrual cycle and its effect on inflammatory bowel disease and irritable bowel syndrome: a prevalence study. Am. J. Gastroenterol. 1998, 93:1867-1872.
227. Karl A., Schaefer M., Malta L.S., Dorfel D., Rohleder N., Werner A. A meta-analysis of structural brain abnormalities in PTSD. Neurosci. Biobehav. Rev. 2006, 30:1004-1031.
228. Karling P., Nyhlin H., Wiklund U., Sjoberg M., Olofsson B.O., Bjerle P. Spectral analysis of heart rate variability in patients with irritable bowel syndrome. Scand. J. Gastroenterol. 1998, 33:572-576.
229. Kassinen A., Krogius-Kurikka L., Makivuokko H., Rinttila T., Paulin L., Corander J., Malinen E., Apajalahti J., Palva A. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. Gastroenterology 2007, 133:24-33.
230. Keefe F.J., Rumble M.E., Scipio C.D., Giordano L.A., Perri L.M. Psychological aspects of persistent pain: current state of the science. J. Pain 2004, 5:195-211.
231. Kilkens T.O., Honig A., Fekkes D., Brummer R.J. The effects of an acute serotonergic challenge on brain-gut responses in irritable bowel syndrome patients and controls. Aliment. Pharmacol. Ther. 2005, 22:865-874.
232. Kilkens T.O., Honig A., van Nieuwenhoven M.A., Riedel W.J., Brummer R.J. Acute tryptophan depletion affects brain-gut responses in irritable bowel syndrome patients and controls. Gut 2004, 53:1794-1800.
233. Kinsey S.G., Bailey M.T., Sheridan J.F., Padgett D.A., Avitsur R. Repeated social defeat causes increased anxiety-like behavior and alters splenocyte function in C57BL/6 and CD-1 mice. Brain Behav. Immun. 2007, 21:458-466.
234. Kleen J., Sitomer M., Killeen P., Conrad C. Chronic stress impairs spatial memory and motivation for reward without disrupting motor ability and motivation to explore. Behav. Neurosci. 2006, 120:842-851.
235. Knapp P., Beck A.T. Cognitive therapy: foundations, conceptual models, applications and research. Rev. Bras. Psiquiatr. 2008, 30(Suppl. 2):s54-s64.
236. Koloski N.A., Talley N.J., Boyce P.M. A history of abuse in community subjects with irritable bowel syndrome and functional dyspepsia: the role of other psychosocial variables. Digestion 2005, 72:86-96.
237. Konishi S., Kawazu M., Uchida I., Kikyo H., Asakura I., Miyashita Y. Contribution of working memory to transient activation in human inferior prefrontal cortex during performance of the Wisconsin Card Sorting Test. Cereb. Cortex 1999, 9:745-753.
238. Kosten T.A., Lee H.J., Kim J.J. Neonatal handling alters learning in adult male and female rats in a task-specific manner. Brain Res. 2007, 1154:144-153.
239. Krabbe K.S., Reichenberg A., Yirmiya R., Smed A., Pedersen B.K., Bruunsgaard H. Low-dose endotoxemia and human neuropsychological functions. Brain Behav. Immun. 2005, 19:453-460.
240. Kraneveld A.D., Rijnierse A., Nijkamp F.B., Garssen J. Neuro-immune interactions in inflammatory bowel disease and irritable bowel syndrome: future therapeutic targets. Eur. J. Pharmacol. 2008, 585:361-374.
241. Kuhlmann S., Wolf O.T. Arousal and cortisol interact in modulating memory consolidation in healthy young men. Behav. Neurosci. 2006, 120:217-223.
242. Kukolja J., Schlapfer T.E., Keysers C., Klingmuller D., Maier W., Fink G.R., Hurlemann R. Modeling a negative response bias in the human amygdala by noradrenergic-glucocorticoid interactions. J. Neurosci. 2008, 28:12868-12876.
243. Kumar D. Abnormal REM sleep in the irritable bowel syndrome. Gastroenterology 1992, 130:12-17.
244. Kumar D., Wingate D.L. The irritable bowel syndrome: a paroxysmal motor disorder. Lancet 1985, 2:973-977.
245. Kwan C.L., Diamant N.E., Pope G., Mikula K., Mikulis D.J., Davis K.D. Abnormal forebrain activity in functional bowel disorder patients with chronic pain. Neurology 2005, 65:1268-1277.
246. LaBar K.S., Cabeza R. Cognitive neuroscience of emotional memory. Nat. Rev. Neurosci. 2006, 7:54-64.
247. Labus J.S., Naliboff B.N., Fallon J., Berman S.M., Suyenobu B., Bueller J.A., Mandelkern M., Mayer E.A. Sex differences in brain activity during aversive visceral stimulation and its expectation in patients with chronic abdominal pain: a network analysis. Neuroimage 2008, 41:1032-1043.
248. Lackner J.M., Lou Coad M., Mertz H.R., Wack D.S., Katz L.A., Krasner S.S., Firth R., Mahl T.C., Lockwood A.H. Cognitive therapy for irritable bowel syndrome is associated with reduced limbic activity, GI symptoms, and anxiety. Behav. Res. Ther. 2006, 44:621-638.
249. Lackner J.M., Jaccard J., Krasner S.S., Katz L.A., Gudleski G.D., Blanchard E.B. How does cognitive behavior therapy for irritable bowel syndrome work?. A mediational analysis of a randomized clinical trial. Gastroenterology 2007, 133:433-444.
250. Lackner J.M., Mesmer C., Morley S., Dowzer C., Hamilton S. Psychological treatments for irritable bowel syndrome: a systematic review and meta-analysis. J. Consult. Clin. Psychol. 2004, 72:1100-1113.
251. Lackner J.M., Quigley B.M. Pain catastrophizing mediates the relationship between worry and pain suffering in patients with irritable bowel syndrome. Behav. Res. Ther. 2005, 43:943-957.
252. Lacosta S., Merali Z., Anisman H. Influence of acute and repeated interleukin-2 administration on spatial learning, locomotor activity, exploratory behaviors, and anxiety. Behav. Neurosci. 1999, 113:1030-1041.
253. Ladd C.O., Huot R.L., Thrivikraman K.V., Nemeroff C.B., Plotsky P.M. Long-term adaptations in glucocorticoid receptor and mineralocorticoid receptor mRNA and negative feedback on the hypothalamo-pituitary-adrenal axis following neonatal maternal separation. Biol. Psychiatry 2004, 55:367-375.
254. Lagopoulos J., Malhi G.S. A functional magnetic resonance imaging study of emotional Stroop in euthymic bipolar disorder. Neuroreport 2007, 18:1583-1587.
255. Lapiz-Bluhm M.D., Soto-Pina A.E., Hensler J.G., Morilak D.A. Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats. Psychopharmacology (Berl.) 2009, 202:329-341.
256. Lazarus R.S., Folkman S. Stress, Appraisal and Coping 1984, Springer Publication Company, NY.
257. Lea R., Houghton L.A., Calvert E.L., Larder S., Gonsalkorale W.M., Whelan V., Randles J., Cooper P., Cruickshanks P., Miller V., Whorwell P.J. Gut-focused hypnotherapy normalizes disordered rectal sensitivity in patients with irritable bowel syndrome. Aliment. Pharmacol. Ther. 2003, 17:635-642.
258. Lee H.-F., Lu C.-L., Hsieh J.-C., Yeh T.-C., Cheng C.-M., Chang F.-Y., Lee S.-D. Aberrant neuro-network in processing of visceral placebo analgesia among IBS patients. Gastroenterology 2010, 138(Suppl. 1):S-117-S-118.
259. Lee K.J., Tack J. Altered intestinal microbiota in irritable bowel syndrome. Neurogastroenterol. Motil. 2010, 22:493-498.
260. Lee S.Y., Kim J.H., Sung I.K., Park H.S., Jin C.J., Choe W.H., Kwon S.Y., Lee C.H., Choi K.W. Irritable bowel syndrome is more common in women regardless of the menstrual phase: a Rome II-based survey. J. Korean Med. Sci. 2007, 22:851-854.
261. Lehmann J., Feldon J. Long-term biobehavioral effects of maternal separation in the rat: consistent or confusing?. Rev. Neurosci. 2000, 11:383-408.
262. Lembo T., Naliboff B., Munakata J., Fullerton S., Saba L., Tung S., Schmulson M., Mayer E.A. Symptoms and visceral perception in patients with pain-predominant irritable bowel syndrome. Am. J. Gastroenterol. 1999, 94:1320-1326.
263. Levine J.D., Gordon N.C. Influence of the method of drug administration on analgesic response. Nature 1984, 312:755-756.
264. Levine J.D., Gordon N.C., Fields H.L. The mechanism of placebo analgesia. Lancet 1978, 2:654-657.
265. Li A.J., Katafuchi T., Oda S., Hori T., Oomura Y. Interleukin-6 inhibits long-term potentiation in rat hippocampal slices. Brain Res. 1997, 748:30-38.
266. Li S., Wang C., Wang W., Dong H., Hou P., Tang Y. Chronic mild stress impairs cognition in mice: from brain homeostasis to behavior. Life Sci. 2008, 82:934-942.
267. Li W., Dowd S.E., Scurlock B., Acosta-Martinez V., Lyte M. Memory and learning behavior in mice is temporally associated with diet-induced alterations in gut bacteria. Physiol. Behav. 2009, 96:557-567.
268. Liang K.C., Juler R.G., McGaugh J.L. Modulating effects of posttraining epinephrine on memory: involvement of the amygdala noradrenergic system. Brain Res. 1986, 368:125-133.
269. Lieberman M.D., Jarcho J.M., Berman S., Naliboff B.D., Suyenobu B.Y., Mandelkern M., Mayer E.A. The neural correlates of placebo effects: a disruption account. Neuroimage 2004, 22:447-455.
270. Liebregts T., Adam B., Bredack C., Roth A., Heinzel S., Lester S., Downie-Doyle S., Smith E., Drew P., Talley N.J., Holtmann G. Immune activation in patients with irritable bowel syndrome. Gastroenterology 2007, 132:913-920.
271. Liston C., Miller M.M., Goldwater D.S., Radley J.J., Rocher A.B., Hof P.R., Morrison J.H., McEwen B.S. Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J. Neurosci. 2006, 26:7870-7874.
272. Lockwood A.H., Linn R.T., Szymanski H., Coad M.L., Wack D.S. Mapping the neural systems that mediate the Paced Auditory Serial Addition Task (PASAT). J. Int. Neuropsychol. Soc. 2004, 10:26-34.
273. Loftis J.M., Huckans M., Morasco B.J. Neuroimmune mechanisms of cytokine-induced depression: current theories and novel treatment strategies. Neurobiol. Dis. 2010, 37:519-533.
274. Longe S., Wise R., Bantick S., Lloyd D., Johansen-Berg H., McGlone F., Tracèy I. Counter-stimulatory effects on pain perception and processing are significantly altered by attention: an fMRI study. Neuroreport 2001, 12:2021-2025.
275. Longstreth G.F., Thompson W.G., Chey W.D., Houghton L.A., Mearin F., Spiller R.C. Functional bowel disorders. Gastroenterology 2006, 130:1480-1491.
276. Longstreth G.F., Wilson A., Knight K., Wong J., Chiou C.F., Barghout V., Frech F., Ofman J.J. Irritable bowel syndrome, health care use, and costs: a U.S. managed care perspective. Am. J. Gastroenterol. 2003, 98:600-607.
277. Lu C.-L., Chang F.-Y. Placebo effect in patients with irritable bowel syndrome. J. Gastroenterol. Hepatol. 2011, 26(Suppl. 3):116-118.
278. Lupien S., Gillin C., Hauger R. Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: a dose-response study in humans. Behav. Neurosci. 1999, 113:420-430.
279. Lupien S., Lecours A.R., Lussier I., Schwartz G., Nair N.P.V., Meaney M.J. Basal cortisol-levels and cognitive deficits in human aging. J. Neurosci. 1994, 14:2893-2903.
280. Lupien S.J., Gaudreau S., Tchiteya B.M., Maheu F., Sharma S., Nair N.P.V., Hauger R.L., McEwen B.S., Meaney M.J. Stress-induced declarative memory impairment healthy elderly subjects: relationship to cortisol reactivity. J. Clin. Endocrinol. Metab. 1997, 82:2070-2075.
281. Lupien S.J., Maheu F., Tu M., Fiocco A., Schramek T.E. The effects of stress and stress hormones on human cognition: implications for the field of brain and cognition. Brain Cogn. 2007, 65:209-237.
282. Lupien S.J., McEwen B.S., Gunnar M.R., Heim C. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat. Rev. 2009, 10:434-445.
283. Lupien S.J., Wilkinson C.W., Briere S., Menard C., Ng Ying Kin N.M., Nair N.P. The modulatory effects of corticosteroids on cognition: studies in young human populations. Psychoneuroendocrinology 2002, 27:401-416.
284. Lyte M., Li W., Opitz N., Gaykema R.P., Goehler L.E. Induction of anxiety-like behavior in mice during the initial stages of infection with the agent of murine colonic hyperplasia Citrobacter rodentium. Physiol. Behav. 2006, 89:350-357.
285. Maddock R.J., Garrett A.S., Buonocore M.H. Posterior cingulate cortex activation by emotional words: fMRI evidence from a valence decision task. Hum. Brain Mapp. 2003, 18:30-41.
286. Madruga C., Xavier L.L., Achaval M., Sanvitto G.L., Lucion A.B. Early handling, but not maternal separation, decreases emotional responses in two paradigms of fear without changes in mesolimbic dopamine. Behav. Brain Res. 2006, 166:241-246.
287. Majer M., Nater U.M., Lin J.M., Capuron L., Reeves W.C. Association of childhood trauma with cognitive function in healthy adults: a pilot study. BMC Neurol 2010, 10:61.
288. Maki P.M., Rich J.B., Rosenbaum R.S. Implicit memory varies across the menstrual cycle: estrogen effects in young women. Neuropsychologia 2002, 40:518-529.
289. Malinen E., Rinttilä T., Kajander K., Mättö J., Kassinen A., Krogius L., Saarela M., Korpela R., Palva A. Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR. Am. J. Gastroenterol. 2005, 100:373-382.
290. Manabe N., Tanaka T., Hata J., Kusunoki H., Haruma K. Pathophysiology underlying irritable bowel syndrome-from the viewpoint of dysfunction of autonomic nervous system activity. J. Smooth Muscle Res. 2009, 45:15-23.
291. Manni L., Aloe L., Fiore M. Changes in cognition induced by social isolation in the mouse are restored by electro-acupuncture. Physiol. Behav. 2009, 98:537-542.
292. Marsland A., Petersen K., Sathanoori R., Muldoon M., Neumann S., Ryan C., Flory J., Manuck S. Interleukin-6 covaries inversely with cognitive performance among middle-aged community volunteers. Psychosom. Med. 2006, 68:895-903.
293. Martin M., Chapman S.C. Cognitive processing in putative functional gastrointestinal disorder: rumination yields orientation to social threat not pain. Eur. J. Pain 2010, 14:207-213.
294. Matsumoto Y., Watanabe S., Suh Y.H., Yamamoto T. Effects of intrahippocampal CT105, a carboxyl terminal fragment of beta-amyloid precursor protein, alone/with inflammatory cytokines on working memory in rats. J. Neurochem. 2002, 82:234-239.
295. Matto J., Maunuksela L., Kajander K., Palva A., Korpela R., Kassinen A., Saarela M. Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome-a longitudinal study in IBS and control subjects. FEMS Immunol. Med. Microbiol. 2005, 43:213-222.
296. Mayer E., Berman S., Suyenobu B., Labus J., Mandelkern M., Naliboff B., Chang L. Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis. Pain 2005, 115:398-409.
297. Mayer E., Tillisch K., Bradesi S. Review article: modulation of the brain-gut axis as a therapeutic approach in gastrointestinal disease. Aliment. Pharmacol. Ther. 2006, 24:919-933.
298. Mayer E.A. The neurobiology of stress and gastrointestinal disease. Gut 2000, 47:861-869.
299. Mayer E.A., Aziz Q., Coen S., Kern M., Labus J.S., Lane R., Kuo B., Naliboff B., Tracey I. Brain imaging approaches to the study of functional GI disorders: a Rome working team report. Neurogastroenterol. Motil. 2009, 21:579-596.
300. Mayer E.A., Collins S.M. Evolving pathophysiologic models of functional gastrointestinal disorders. Gastroenterology 2002, 122:2032-2048.
301. Mayer E.A., Tillisch K. The brain-gut axis in abdominal pain syndromes. Annu. Rev. Med. 2011, 62:381-396.
302. McAfoose J., Koerner H., Baune B. The effects of TNF deficiency on age-related cognitive performance. Psychoneuroendocrinology 2009, 34:615-619.
303. McEwen B.S. Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling. Ann. N.Y. Acad. Sci. 2010, 1204(Suppl.):E38-E59.
304. McFarland L.V., Dublin S. Meta-analysis of probiotics for the treatment of irritable bowel syndrome. World J. Gastroenterol. 2008, 14:2650-2661.
305. McGaugh J.L. The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu. Rev. Neurosci. 2004, 27:1-28.
306. McKee D.P., Quigley E.M. Intestinal motility in irritable bowel syndrome: is IBS a motility disorder? Part 1. Definition of IBS and colonic motility. Dig. Dis. Sci. 1993, 38:1761-1772.
307. McKernan D.P., Fitzgerald P., Dinan T.G., Cryan J.F. The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat. Neurogastroenterol. Motil. 2010, 22:1029-1035. e1268.
308. McKernan D.P., Gaszner G., Quigley E.M., Cryan J.F., Dinan T.G. Altered peripheral toll-like receptor responses in the irritable bowel syndrome. Aliment. Pharmacol. Ther. 2011, 33:1045-1052.
309. McKernan D.P., Nolan A., Brint E.K., O'Mahony S.M., Hyland N.P., Cryan J.F., Dinan T.G. Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome. PLoS One 2009, 4:e8226.
310. McLay R.N., Freeman S.M., Zadina J.E. Chronic corticosterone impairs memory performance in the Barnes maze. Physiol. Behav. 1998, 63:933-937.
311. Mentzel H.J., Gaser C., Volz H.P., Rzanny R., Häger F., Sauer H., Kaiser W.A. Cognitive stimulation with the Wisconsin Card Sorting Test: functional MR imaging at 1.5T. Radiology 1998, 207:399-404.
312. Merlot E., Moze E., Dantzer R., Neveu P.J. Importance of fighting in the immune effects of social defeat. Physiol. Behav. 2003, 80:351-357.
313. Mertz H., Naliboff B., Munakata J., Niazi N., Mayer E. Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology 1995, 109:40-52.
314. Messaoudi M., Lalonde R., Violle N., Javelot H., Desor D., Nejdi A., Bisson J.F., Rougeot C., Pichelin M., Cazaubiel M., Cazaubiel J.M. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br. J. Nutr. 2011, 105:755-764.
315. Miller A.R., North C.S., Clouse R.E., Wetzel R.D., Spitznagel E.L., Alpers D.H. The association of irritable bowel syndrome and somatization disorder. Ann. Clin. Psychiatry 2001, 13:25-30.
316. Miller G.E., Rohleder N., Stetler C., Kirschbaum C. Clinical depression and regulation of the inflammatory response during acute stress. Psychosom. Med. 2005, 67:679-687.
317. Miller V., Whorwell P.J. Hypnotherapy for functional gastrointestinal disorders: a review. Int. J. Clin. Exp. Hypn. 2009, 57:279-292.
318. Miracle A.D., Brace M.F., Huyck K.D., Singler S.A., Wellman C.L. Chronic stress impairs recall of extinction of conditioned fear. Neurobiol. Learn. Mem. 2006, 85:213-218.
319. Mizoguchi K., Yuzurihara M., Ishige A., Sasaki H., Chui D.H., Tabira T. Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. J. Neurosci. 2000, 15:1568-1574.
320. Moayyedi P., Ford A.C., Talley N.J., Cremonini F., Foxx-Orenstein A.E., Brandt L.J., Quigley E.M. The efficacy of probiotics in the treatment of irritable bowel syndrome: a systematic review. Gut 2010, 59:325-332.
321. Monroy E., Hernandez-Torres E., Flores G. Maternal separation disrupts dendritic morphology of neurons in prefrontal cortex, hippocampus, and nucleus accumbens in male rat offspring. J. Chem. Neuroanat. 2010, 40:93-101.
322. Moore J., Barlow D., Jewell D., Kennedy S. Do gastrointestinal symptoms vary with the menstrual cycle?. Br. J. Obstet. Gynaecol. 1998, 105:1322-1325.
323. Moriarty O., McGuire B.E., Finn D.P. The effect of pain on cognitive function: a review of clinical and preclinical research. Prog. Neurobiol. 2011, 93:385-404.
324. Morrison S.E., Salzman C.D. Re-valuing the amygdala. Curr. Opin. Neurobiol. 2010, 20:221-230.
325. Mudipalli R.S., Remes-Troche J.M., Andersen L., Rao S.S. Functional chest pain: esophageal or overlapping functional disorder. J. Clin. Gastroenterol. 2007, 41:264-269.
326. Muller-Lissner S.A., Bollani S., Brummer R.J., Coremans G., Dapoigny M., Marshall J.K., Muris J.W., Oberndorff-Klein Wolthuis A., Pace F., Rodrigo L., Stockbrugger R., Vatn M.H. Epidemiological aspects of irritable bowel syndrome in Europe and North America. Digestion 2001, 64:200-204.
327. Mykletun A., Jacka F., Williams L., Pasco J., Henry M., Nicholson G.C., Kotowicz M.A., Berk M. Prevalence of mood and anxiety disorder in self reported irritable bowel syndrome (IBS). An epidemiological population based study of women. BMC Gastroenterol. 2010, 10:88.
328. Nagahama Y., Okada T., Katsumi Y., Hayashi T., Yamauchi H., Oyanagi C., Konishi J., Fukuyama H., Shibasaki H. Dissociable mechanisms of attentional control within the human prefrontal cortex. Cereb. Cortex 2001, 11:85-92.
329. Nakajima S., Ohsawa I., Ohta S., Ohno M., Mikami T. Regular voluntary exercise cures stress-induced impairment of cognitive function and cell proliferation accompanied by increases in cerebral IGF-1 and GST activity in mice. Behav. Brain Res. 2010, 211:178-184.
330. Naliboff B.D., Berman S., Chang L., Derbyshire S.W., Suyenobu B., Vogt B.A., Mandelkern M., Mayer E.A. Sex-related differences in IBS patients: central processing of visceral stimuli. Gastroenterology 2003, 124:1738-1747.
331. Naliboff B.D., Berman S., Suyenobu B., Labus J.S., Chang L., Stains J., Mandelkern M.A., Mayer E.A. Longitudinal change in perceptual and brain activation response to visceral stimuli in irritable bowel syndrome patients. Gastroenterology 2006, 131:352-365.
332. Naliboff B.D., Munakata J., Fullerton S., Gracely R.H., Kodner A., Harraf F., Mayer E.A. Evidence for two distinct perceptual alterations in irritable bowel syndrome. Gut 1997, 41:505-512.
333. Navalta C.P., Polcari A., Webster D.M., Boghossian A., Teicher M.H. Effects of childhood sexual abuse on neuropsychological and cognitive function in college women. J. Neuropsychiatry Clin. Neurosci. 2006, 18:45-53.
334. Neal K.R., Hebden J., Spiller R. Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: postal survey of patients. BMJ 1997, 314:779-782.
335. Nemeroff C.B. Neurobiological consequences of childhood trauma. J. Clin. Psychiatry 2004, 65(Suppl. 1):18-28.
336. Neufeld K.A., Foster J.A. Effects of gut microbiota on the brain: implications for psychiatry. J. Psychiatry Neurosci. 2009, 34:230-231.
337. Neufeld K.M., Kang N., Bienenstock J., Foster J.A. Reduced anxiety-like behavior and central neurochemical change in germ-free mice. Neurogastroenterol Motil 2011, 23:255-264.
338. Nicholson J.K., Holmes E., Wilson I.D. Gut microorganisms, mammalian metabolism and personalized health care. Nat. Rev. Microbiol. 2005, 3:431-438.
339. North C.S., Downs D., Clouse R.E., Alrakawi A., Dokucu M.E., Cox J., Spitznagel E.L., Alpers D.H. The presentation of irritable bowel syndrome in the context of somatization disorder. Clin. Gastroenterol. Hepatol. 2004, 2:787-795.
340. Nyhlin H., Ford M.J., Eastwood J., et al. Non-alimentary aspects of the irritable bowel syndrome. J. Psychosom. Res. 1993, 3:155-162.
341. O'Mahony L., McCarthy J., Kelly P., Hurley G., Luo F.Y., Chen K.S., O'Sullivan G.C., Kiely B., Collins J.K., Shanahan F., Quigley E.M.M. Lactobacillus and Bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology 2005, 128:541-551.
342. O'Mahony S., Chua A.S., Quigley E.M., Clarke G., Shanahan F., Keeling P.W., Dinan T.G. Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model. Neurogastroenterol. Motil. 2008, 20:680-688.
343. O'Mahony S.M., Hyland N.P., Dinan T.G., Cryan J.F. Maternal separation as a model of brain-gut axis dysfunction. Psychopharmacology (Berl) 2011, 214:71-88.
344. O'Mahony S.M., Marchesi J.R., Scully P., Codling C., Ceolho A.M., Quigley E.M., Cryan J.F., Dinan T.G. Early life stress alters behavior, immunity, and microbiota in rats: implications for irritable bowel syndrome and psychiatric illnesses. Biol. Psychiatry 2009, 65:263-267.
345. O'Malley D., Dinan T.G., Cryan J.F. Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood. Psychopharmacology (Berl) 2011, 214:221-229.
346. O'Malley D., Liston M., Hyland N.P., Dinan T.G., Cryan J.F. Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism. Am. J. Physiol. Gastrointest. Liver Physiol. 2011, 300:G241-G252.
347. O'Malley D., Quigley E.M., Dinan T.G., Cryan J.F. Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome?. Brain Behav. Immun. 2011, PubMed PMID: 21536124 (Epub ahead of print).
348. Ochsner K.N., Gross J.J. The cognitive control of emotion. Trends Cogn. Sci. 2005, 9:242-249.
349. Oosterman J.M., Derksen L.C., van Wijck A.J., Veldhuijzen D.S., Kessels R.P. Memory functions in chronic pain: examining contributions of attention and age to test performance. Clin. J. Pain 2011, 27:70-75.
350. Oei N.Y., Everaerd W.T., Elzinga B.M., van Well S., Bermond B. Psychosocial stress impairs working memory at high loads: an association with cortisol levels and memory retrieval. Stress Int. J. Biol. Stress 2006, 9:133-141.
351. Oerlemans S., van Cranenburgh O., Herremans P.J., Spreeuwenberg P., van Dulmen S. Intervening on cognitions and behavior in irritable bowel syndrome: a feasibility trial using PDAs. J. Psychosom. Res. 2011, 70:267-277.
352. Ohira H., Nomura M., Ichikawa N., Isowa T., Iidaka T., Sato A., Fukuyama S., Nakajima T., Yamada J. Association of neural and physiological responses during voluntary emotion suppression. Neuroimage 2006, 29:721-733.
353. Ohman L., Simren M. New insights into the pathogenesis and pathophysiology of irritable bowel syndrome. Dig. Liver Dis. 2007, 39:201-215.
354. Oitzl M.S., van Oers H., Schobitz B., de Kloet E.R. Interleukin-1β, but not interleukin-6, impairs spatial navigation learning. Brain Res. 1993, 613:160-163.
355. Orr W.C. Sleep and functional gastrointestinal disorders: can bad bowels cause bad dreams?. Am. J. Gastroenterol. 2000, 95:1118-1121.
356. Owen A.M., Evans A.C., Pertrides M. Evidence for a two-stage model of working memory processing within the lateral frontal cortex: a positron emission tomography study. Cereb. Cortex 1996, 6:31-38.
357. Owen A.M., McMillan K.M., Laird A.R., Bullmore E. N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies. Hum. Brain Mapp. 2005, 25:46-59.
358. Owen A.M., Sahakian B.J., Semple J., Polkey C.E., Robbins T.W. Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man. Neuropsychologia 1995, 33:1-24.
359. Palsson O.S., Whitehead W.E. The growing case for hypnosis as adjunctive therapy for functional gastrointestinal disorders. Gastroenterology 2002, 123:2132-2135.
360. Park C.R., Campbell A.M., Diamond D.M. Chronic psychosocial stress impairs learning and memory and increases sensitivity to yohimbine in adult rats. Biol. Psychiatry 2001, 50:994-1004.
361. Park D.C., Glass J.M., Minear M., Crofford L.J. Cognitive function in fibromyalgia patients. Arthritis Rheum. 2001, 44:2125-2133.
362. Park I.H., Park H.J., Chun J.W., Kim E.Y., Kim J.J. Dysfunctional modulation of emotional interference in the medial prefrontal cortex in patients with schizophrenia. Neurosci. Lett. 2008, 440:119-124.
363. Pawlak R., Rao B.S., Melchor J.P., Chattarji S., McEwen B., Strickland S. Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:18201-18206.
364. Payne J.D., Jackson E.D., Ryan L., Hoscheidt S., Jacobs J.W., Nadel L. The impact of stress on neutral and emotional aspects of episodic memory. Memory (Hove, England) 2006, 14:1-16.
365. Pechtel P., Pizzagalli D.A. Effects of early life stress on cognitive and affective function: an integrated review of human literature. Psychopharmacology (Berl.) 2011, 214:55-70.
366. Pessoa L. Emotion and cognition and the amygdala: from " what is it?." to " what's to be done?" Neuropsychologia 2010, 48:3416-3429.
367. Petrovic P., Kalso E., Petersson K.M., Ingvar M. Placebo and opioid analgesia-imaging a shared neuronal network. Science 2002, 295:1737-1740.
368. Petrovic P., Petersson K., Ghatan P., Stone-Elander S., Ingvar M. Pain-related cerebral activation is altered by a distracting cognitive task. Pain 2000, 85:19-30.
369. Peyron R., Laurent B., Garcia-Larrea L. Functional imaging of brain responses to pain. A review and meta-analysis. Neurophysiol. Clin. 2000, 30:263-288.
370. Phan K.L., Fitzgerald D.A., Nathan P.J., Moore G.J., Uhde T.W., Tancer M.E. Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study. Biol. Psychiatry 2005, 57:210-219.
371. Phillips S.M., Sherwin B.B. Variations in memory function and sex steroid hormones across the menstrual cycle. Psychoneuroendocrinology 1992, 17:497-506.
372. Pickering M., Cumiskey D., O'Connor J.J. Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system. Exp. Physiol. 2005, 90:663-670.
373. Piser T.M. Linking the cytokine and neurocircuitry hypotheses of depression: a translational framework for discovery and development of novel anti-depressants. Brain Behav. Immun. 2010, 24:515-524.
374. Pollak S.D., Nelson C.A., Schlaak M.F., Roeber B.J., Wewerka S.S., Wiik K.L., Frenn K.A., Loman M.M., Gunnar M.R. Neurodevelopmental effects of early deprivation in postinstitutionalized children. Child Dev. 2010, 81:224-236.
375. Porter R.J., Barnett N.A., Idey A., McGuckin E.A., O'Brien J.T. Effects of hydrocortisone administration on cognitive function in the elderly. J. Psychopharmacol. 2002, 16:65-71.
376. Posner M.I., Petersen S.E. The attention system of the human brain. Annu. Rev. Neurosci. 1990, 13:25-42.
377. Posserud I., Agerforz P., Ekman R., Bjornsson E.S., Abrahamsson H., Simren M. Altered visceral perceptual and neuroendocrine response in patients with irritable bowel syndrome during mental stress. Gut 2004, 53:1102-1108.
378. Posserud I., Svedlund J., Wallin J., Simren M. Hypervigilance in irritable bowel syndrome compared with organic gastrointestinal disease. J. Psychosom. Res. 2009, 66:399-405.
379. Price D.D., Craggs J., Verne G.N., Perlstein W.M., Robinson M.E. Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients. Pain 2007, 127:63-72.
380. Protopopescu X., Butler T., Pan H., Root J., Altemus M., Polanecsky M., McEwen B., Silbersweig D., Stern E. Hippocampal structural changes across the menstrual cycle. Hippocampus 2008, 18:985-988.
381. Price D.D., Finniss D.G., Benedetti F. A comprehensive review of the placebo effect: recent advances and current thought. Annu. Rev. Psychol. 2008, 59:565-590.
382. Pruessner J.C., Dedovic K., Khalili-Mahani N., Engert V., Pruessner M., Buss C., Renwick R., Dagher A., Meaney M.J., Lupien S. Deactivation of the limbic system during acute psychosocial stress: evidence from positron emission tomography and functional magnetic resonance imaging studies. Biol. Psychiatry 2008, 63:234-240.
383. Pugh C.R., Nguyen K.T., Gonyea J.L., Fleshner M., Wakins L.R., Maier S.F., Rudy J.W. Role of interleukin-1 beta in impairment of contextual fear conditioning caused by social isolation. Behav. Brain Res. 1999, 106:109-118.
384. Quan N., Banks W.A. Brain-immune communication pathways. Brain Behav. Immun. 2007, 21:727-735.
385. Quigley E.M. Changing face of irritable bowel syndrome. World J. Gastroenterol. 2006, 12:1-5.
386. Quigley E.M. The efficacy of probiotics in IBS. J. Clin. Gastroenterol. 2008, 42:S85-S90.
387. Quigley E.M. Prebiotics and probiotics; modifying and mining the microbiota. Pharmacol. Res. 2010, 61:213-218.
388. Raichle M.E., Mintun M.A. Brain work and brain imaging. Annu. Rev. Neurosci. 2006, 29:449-476.
389. Rainville P., Duncan G.H., Price D.D., Carrier B., Bushnell M.C. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 1997, 15:968-971.
390. Ramos B., Stark D., Verduzco L., van Dyck C.H., Arnsten A.F.T. Alpha-2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals. Learn. Mem. 2006, 13:770-776.
391. Ramos B.P., Arnsten A.F. Adrenergic pharmacology and cognition: focus on the prefrontal cortex. Pharmacol. Ther. 2007, 113:523-536.
392. Rauch S.L., Shin L.M., Phelps E.A. Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research-past, present, and future. Biol. Psychiatry 2006, 60:376-382.
393. Reichenberg A., Kraus T., Haack M., Schuld A., Pollmächer T., Yirmiya R. Endotoxin-induced changes in food consumption in healthy volunteers are associated with TNF-[alpha] and IL-6 secretion. Psychoneuroendocrinology 2002, 27:945-956.
394. Remy F., Frankenstein U.N., Mincic A., Tomanek B., Stroman P.W. Pain modulates cerebral activity during cognitive performance. Neuroimage 2003, 19:655-664.
395. Riedl A., Schmidtmann M., Stengel A., Goebel M., Wisser A.S., Klapp B.F., Monnikes H. Somatic comorbidities of irritable bowel syndrome: a systematic analysis. J. Psychosom. Res. 2008, 64:573-582.
396. Ringel Y., Drossman D.A., Leserman J.L., Suyenobu B.Y., Wilber K., Lin W., Whitehead W.E., Naliboff B.D., Berman S., Mayer E.A. Effect of abuse history on pain reports and brain responses to aversive visceral stimulation: an FMRI study. Gastroenterology 2008, 134:396-404.
397. Robbins T.W., Roberts A.C. Differential regulation of fronto-executive function by the monoamines and acetylcholine. Cereb. Cortex 2007, 17(Suppl. 1):i151-i160.
398. Roceri M., Hendriks W., Racagni G., Ellenbroek B.A., Riva M.A. Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Mol. Psychiatry 2002, 7:609-616.
399. Rogers M.A., Kasai K., Koji M., Fukuda R., Iwanami A., Nakagome K., Fukuda M., Kato N. Executive and prefrontal dysfunction in unipolar depression: a review of neuropsychological and imaging evidence. Neurosci. Res. 2004, 50:1-11.
400. Rolls E.T., Grabenhorst F. The orbitofrontal cortex and beyond: from affect to decision-making. Prog. Neurobiol. 2008, 86:216-244.
401. Roozendaal B., Hui G.K., Hui I.R., Berlau D.J., McGaugh J.L., Weinberger N.M. Basolateral amygdala noradrenergic activity mediates corticosterone-induced enhancement of auditory fear conditioning. Neurobiol. Learn. Mem. 2006, 86:249-255.
402. Roozendaal B., McEwen B.S., Chattarji S. Stress, memory and the amygdala. Nat Rev Neurosci 2009, 10:423-433.
403. Rosczyk H., Sparkman N., Johnson R. Neuroinflammation and cognitive function in aged mice following minor surgery. Exp. Gerontol. 2008, 43:840-846.
404. Rosenberg L., Park S. Verbal and spatial functions across the menstrual cycle in healthy young women. Psychoneuroendocrinology 2002, 27:835-841.
405. Ross F.M., Allan S.M., Rothwell N.J., Verkhratsky A. A dual role for interleukin-1 in LTP in mouse hippocampal slices. J. Neuroimmunol. 2003, 144:61-67.
406. Rowe J.B., Owen A.M., Johnsrude I.S., Passingham R.E. Imaging the mental components of a planning task. Neuropsychologia 2001, 39:315-327.
407. Sabsevitz D.S., Swanson S.J., Hammeke T.A., Spanaki M.V., Possing E.T., Morris G.L.r., Mueller W.M., Binder J.R. Use of preoperative functional neuroimaging to predict language deficits from epilepsy surgery. Neurology 2003, 10:1788-1792.
408. Salehi B., Cordero M.I., Sandi C. Learning under stress: the inverted-U-shape function revisited. Learn. Mem. 2010, 17:522-530.
409. Salonen A., de Vos W.M., Palva A. Gastrointestinal microbiota in irritable bowel syndrome: present state and perspectives. Microbiology (Reading, England) 2010, 156:3205-3215.
410. Sapolsky R.M., Krey L.C., McEwen B.S. Prolonged glucocorticoid exposure reduces hippocampal neuron number: implications for aging. J. Neurosci. 1985, 5:1222-1227.
411. Sapolsky R.M., Krey L.C., McEwen B.S. The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocr. Rev. 1986, 7:284-301.
412. Sara S.J. The locus coeruleus and noradrenergic modulation of cognition. Nat. Rev. 2009, 10:211-223.
413. Savignac H.M., Hyland N.P., Dinan T.G., Cryan J.F. The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain. Behav Brain Res 2011, 216:576-584.
414. Schacter D.L., Tulving E. Memory Systems 1994 1994, MIT Press, Cambridge, MA.
415. Scherbel U., Raghupathi R., Nakamura M., Saatman K.E., Trojanowski J.Q., Neugebauer E., Marino M.W., McIntosh T.K. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:8721-8726.
416. Schoofs D., Preuss D., Wolf O.T. Psychosocial stress induces working memory impairments in an n-back paradigm. Psychoneuroendocrinology 2008, 33:643-653.
417. Schram M.T., Euser S.M., de Craen A.J., Witteman J.C., Frolich M., Hofman A., Jolles J., Breteler M.M., Westendorp R.G. Systemic markers of inflammation and cognitive decline in old age. J. Am. Geriatr. Soc. 2007, 55:708-716.
418. Schulkin J., Gold P.W., McEwen B.S. Induction of corticotropin-releasing hormone gene expression by glucocorticoids: implication for understanding the states of fear and anxiety and allostatic load. Psychoneuroendocrinology 1998, 23:219-243.
419. Scott D.J., Stohler C.S., Egnatuk C.M., Wang H., Koeppe R.A., Zubieta J.K. Placebo and nocebo effects are defined by opposite opioid and dopaminergic responses. Arch. Gen. Psychiatry 2008, 65:220-231.
420. Scully P., McKernan D.P., Keohane J., Groeger D., Shanahan F., Dinan T.G., Quigley E.M. Plasma cytokine profiles in females with irritable bowel syndrome and extra-intestinal co-morbidity. Am. J. Gastroenterol. 2010, 105:2235-2243.
421. Seeman T.E., Crimmins E., Huang M.H., Singer B., Bucur A., Gruenewald T., Berkman L.F., Reuben D.B. Cumulative biological risk and socio-economic differences in mortality: MacArthur studies of successful aging. Soc. Sci. Med. 2004, 58:1985-1997.
422. Seminowicz D.A., Davis K.D. Pain enhances functional connectivity of a brain network evoked by performance of a cognitive task. J. Neurophysiol. 2007, 97:3651-3659.
423. Seminowicz D.A., Labus J.S., Bueller J.A., Tillisch K., Naliboff B.D., Bushnell M.C., Mayer E.A. Regional gray matter density changes in brains of patients with irritable bowel syndrome. Gastroenterology 2010, 139:48-57. e42.
424. Servatius R.J., Shors T.J. Exposure to inescapable stress persistently facilitates associative and nonassociative learning in rats. Behav. Neurosci. 1994, 108:1101-1106.
425. Shallice T., Fletcher P., Frith C.D., Grasby P., Frackowiak R.S., Dolan R.J. Brain regions associated with acquisition and retrieval of verbal episodic memory. Nature 1994, 368:633-635.
426. Sherwin B.B. Estrogen and cognitive functioning in women. Endocr. Rev. 2003, 24:133-151.
427. Sherwin B.B., Henry J.F. Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: a critical review. Front. Neuroendocrinol. 2008, 29:88-113.
428. Sjogren P., Christrup L.L., Petersen M.A., Hojsted J. Neuropsychological assessment of chronic non-malignant pain patients treated in a multidisciplinary pain centre. Eur. J. Pain 2005, 9:453-462.
429. Smeets T., Jelicic M., Merckelbach H. The effect of acute stress on memory depends on word valence. Int. J. Psychophysiol. 2006, 62:30-37.
430. Smeets T., Wolf O.T., Giesbrecht T., Sijstermans K., Telgen S., Joels M. Stress selectively and lastingly promotes learning of context-related high arousing information. Psychoneuroendocrinology 2009, 34:1152-1161.
431. Smith S.M., Vale W.W. The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues Clin. Neurosci. 2006, 8:383-395.
432. Soliman A., O'Driscoll G.A., Pruessner J., Holahan A.L., Boileau I., Gagnon D., Dagher A. Stress-induced dopamine release in humans at risk of psychosis: a [11C]raclopride PET study. Neuropsychopharmacology 2008, 33:2033-2041.
433. Song C., Horrobin D. Omega-3 fatty acid ethyl-eicosapentaenoate, but not soybean oil, attenuates memory impairment induced by central IL-1beta administration. J. Lipid Res. 2004, 45:1112-1121.
434. Song L., Che W., Min-Wei W., Murakami Y., Matsumoto K. Impairment of the spatial learning and memory induced by learned helplessness and chronic mild stress. Pharmacol. Biochem. Behav. 2006, 83:186-193.
435. Soufer R., Bremner J.D., Arrighi J.A., Cohen I., Zaret B.L., Burg M.M., Goldman-Rakic P. Cerebral cortical hyperactivation in response to mental stress in patients with coronary artery disease. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:6454-6459.
436. Sparkman N.L., Kohman R.A., Garcia A.K., Boehm G.W. Peripheral lipopolysaccharide administration impairs two-way active avoidance conditioning in C57BL/6J mice. Physiol. Behav. 2005, 85:278-288.
437. Spiegel B.M. The burden of IBS: looking at metrics. Curr. Gastroenterol. Rep. 2009, 11:265-269.
438. Spiegel B.M., Gralnek I.M., Bolus R., Chang L., Dulai G.S., Mayer E.A., Naliboff B. Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. Arch. Intern. Med. 2004, 164:1773-1780.
439. Spiller R.C., Jenkins D., Thornley J.P., Hebden J.M., Wright T., Skinner M., Neal K.R. Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut 2000, 47:804-811.
440. Stellwagen D., Malenka R.C. Synaptic scaling mediated by glial TNF-alpha. Nature 2006, 440:1054-1059.
441. Steptoe A., Hamer M., Chida Y. The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis. Brain Behav. Immun. 2007, 21:901-912.
442. Sterlemann V., Rammes G., Wolf M., Liebl C., Ganea K., Muller M.B., Schmidt M.V. Chronic social stress during adolescence induces cognitive impairment in aged mice. Hippocampus 2010, 20:540-549.
443. Sternberg R.J. Cognitive Psychology Wadsworth 2009, Cengage Learning, Belmont, CA.
444. Stevenson C.W., Spicer C.H., Mason R., Marsden C.A. Early life programming of fear conditioning and extinction in adult male rats. Behav. Brain Res. 2009, 205:505-510.
445. Strauss E., da Costa M.F. The importance of bacterial infections as precipating factors of chronic hepatic encephalopathy in cirrhosis. Hepatogastroenterology 1998, 45:900-904.
446. Strauss E., Sherman E.M.S., Spreen O. Compendium of Neuropsychological Tests: Administration, Norms, and Commentary 2006, Oxford University Press, NY. 3rd ed.
447. Sudo N., Chida Y., Aiba Y., Sonoda J., Oyama N., Yu X.N., Kubo C., Koga Y. Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J. Physiol. 2004, 558:263-275.
448. Sugaya N., Nomura S. Relationship between cognitive appraisals of symptoms and negative mood for subtypes of irritable bowel syndrome. Biopsychosoc. Med. 2008, 2:9.
449. Sullivan M.J., Thorn B., Haythornthwaite J.A., Keefe F., Martin M., Bradley L.A., Lefebvre J.C. Theoretical perspectives on the relation between catastrophizing and pain. Clin. J. Pain 2001, 17:65-71.
450. Sullivan M.J.L., Rodgers W.M., Wilson P.M., Bell G.J., Murray T.C., Fraser S.N. An experimental investigation of the relation between catastrophizing and activity intolerance. Pain 2002, 100:47-53.
451. Sullivan S.N. A prospective study of unexplained visible abdominal bloating. N. Z. Med. J. 1994, 107:428-430.
452. Sun X., Zhang X., Chen X., Zhang P., Bao M., Zhang D., Chen J., He S., Hu X. Age-dependent brain activation during forward and backward digit recall revealed by fMRI. Neuroimage 2005, 26:36-47.
453. Sweeney J.A., Kmiec J.A., Kupfer D.J. Neuropsychologic impairments in bipolar and unipolar mood disorders on the CANTAB neurocognitive battery. Biol. Psychiatry 2000, 48:674-684.
454. Talley N.J. Irritable bowel syndrome. Intern. Med. J. 2006, 36:724-728.
455. Talley N.J., Howell S., Poulton R. The irritable bowel syndrome and psychiatric disorders in the community: is there a link?. Am. J. Gastroenterol. 2001, 96:1072-1079.
456. Tana M.G., Montin E., Cerutti S., Bianchi A.M. Exploring cortical attentional system by using fMRI during a Continuous Perfomance Test. Computational Intelligence And Neuroscience 2010, 329213. 10.1155/2010/329213.
457. Tanaka T., Manabe N., Hata J., Kusunoki H., Ishii M., Sato M., Kamada T., Shiotani A., Haruma K. Characterization of autonomic dysfunction in patients with irritable bowel syndrome using fingertip blood flow. Neurogastroenterol. Motil. 2008, 20:498-504.
458. Tancredi V., D'Antuono M., Cafe C., Giovedi S., Bue M.C., D'Arcangelo G., Onofri F., Benfenati F. The inhibitory effects of interleukin-6 on synaptic plasticity in the rat hippocampus are associated with an inhibition of mitogen-activated protein kinase ERK. J. Neurochem. 2000, 75:634-643.
459. Tancredi V., D'Arcangelo G., Grassi F., Tarroni P., Palmieri G., Santoni A., Eusebi F. Tumor necrosis factor alters synaptic transmission in rat hippocampal slices. Neurosci. Lett. 1992, 146:176-178.
460. Tanji J., Shima K., Mushiake H. Concept-based behavioral planning and the lateral prefrontal cortex. Trends Cogn. Sci. 2007, 11:528-534.
461. Thompson W.G., Longstreth G.F., Drossman D.A., Heaton K.W., Irvine E.J., Muller-Lissner S.A. Functional bowel disorders and functional abdominal pain. Gut 1999, 45(Suppl. 2):II43-II47.
462. Thomson L., Sutherland R. Interleukin-1beta induces anorexia but not spatial learning and memory deficits in the rat. Behav. Brain Res. 2006, 170:302-307.
463. Tillfors M., Furmark T., Marteinsdottir I., Fischer H., Pissiota A., Langstrom B., Fredrikson M. Cerebral blood flow in subjects with social phobia during stressful speaking tasks: a PET study. Am. J. Psychiatry 2001, 158:1220-1226.
464. Tillfors M., Furmark T., Marteinsdottir I., Fredrikson M. Cerebral blood flow during anticipation of public speaking in social phobia: a PET study. Biol. Psychiatry 2002, 52:1113-1119.
465. Tillisch K., Labus J.S. Advances in imaging the brain-gut axis: functional gastrointestinal disorders. Gastroenterology 2011, 140:407-411. e401.
466. Tillisch K., Mayer E.A., Labus J.S. Quantitative meta-analysis identifies brain regions activated during rectal distension in irritable bowel syndrome. Gastroenterology 2011, 140:91-100.
467. Tkachuk G.A., Graff L.A., Martin G.L., Bernstein C.N. Randomized controlled trial of cognitive-behavioral group therapy for irritable bowel syndrome in a medical setting. J. Clin. Psychol. Med. Settings 2003, 10:57-69.
468. Tombaugh T.N. A comprehensive review of the Paced Auditory Serial Addition Test (PASAT). Arch. Clin. Neuropsychol. 2006, 21:53-76.
469. Tomoda A., Sheu Y.S., Rabi K., Suzuki H., Navalta C.P., Polcari A., Teicher M.H. Exposure to parental verbal abuse is associated with increased gray matter volume in superior temporal gyrus. Neuroimage 2011, 54(Suppl. 1):S280-S286.
470. Toner B.B., Segal Z.V., Emmott S., Myran D., Ali A., DiGasbarro I., Stuckless N. Cognitive-behavioral group therapy for patients with irritable bowel syndrome. Int. J. Group Psychother. 1998, 48:215-243.
471. Tops M., van der Pompe G., Baas D., Mulder L.J., Den Boer J.A., Meijman T.F., Korf J. Acute cortisol effects on immediate free recall and recognition of nouns depend on stimulus valence. Psychophysiology 2003, 40:167-173.
472. Tornblom H., Lindberg G., Nyberg B., Veress B. Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome. Gastroenterology 2002, 123:1972-1979.
473. Tottenham N., Hare T.A., Quinn B.T., McCarry T.W., Nurse M., Gilhooly T., Millner A., Galvan A., Davidson M.C., Eigsti I.M., Thomas K.M., Freed P.J., Booma E.S., Gunnar M.R., Altemus M., Aronson J., Casey B.J. Prolonged institutional rearing is associated with atypically large amygdala volume and difficulties in emotion regulation. Dev. Sci. 2010, 13:46-61.
474. Tracey I. Getting the pain you expect: mechanisms of placebo, nocebo and reappraisal effects in humans. Nat. Med. 2010, 16:1277-1283.
475. Tracey I., Mantyh P.W. The cerebral signature for pain perception and its modulation. Neuron 2007, 55:377-391.
476. Tracey I., Ploghaus A., Gati J., Clare S., Smith S., Menon R., Matthews P. Imaging attentional modulation of pain in the periaqueductal gray in humans. J. Neurosci. 2002, 22:2748-2752.
477. Tulving E., Markowitsch H.J. Episodic and declarative memory: role of the hippocampus. Hippocampus 1998, 8:198-204.
478. Uno H., Tarara R., Else J.G., Suleman M.A., Sapolsky R.M. Hippocampal damage associated with prolonged and fatal stress in primates. J. Neurosci. 1989, 9:1705-1711.
479. Valet M., Sprenger T., Boecker H., Willoch F., Rummeny E., Conrad B., Erhard P., Tolle T.R. Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain-an fMRI analysis. Pain 2004, 109:399-408.
480. Vallieres L., Campbell I.L., Gage F.H., Sawchenko P.E. Reduced hippocampal neurogenesis in adult transgenic mice with chronic astrocytic production of interleukin-6. J. Neurosci. 2002, 22:486-492.
481. Van Damme S., Crombez G., Eccleston C. The anticipation of pain modulates spatial attention: evidence for pain-specificity in high-pain catastrophizers. Pain 2004, 111:392-399.
482. van den Heuvel M.P., Hulshoff Pol H.E. Exploring the brain network: a review on resting-state fMRI functional connectivity. Eur. Neuropsychopharmacol. 2010, 20:519-534.
483. van Orshoven N.P., Andriesse G.I., van Schelven L.J., Smout A.J., Akkermans L.M., Oey P.L. Subtle involvement of the parasympathetic nervous system in patients with irritable bowel syndrome. Clin. Auton. Res. 2006, 16:33-39.
484. van Veen V., Holroyd C., Cohen J., Stenger V.A., Carter C.S. Errors without conflict: implications for performance monitoring theories of anterior cingulate cortex. Brain Cogn. 2004, 56:267-276.
485. Vege S.S., Locke G.R., Weaver A.L., Farmer S.A., Melton L.J., Talley N.J. Functional gastrointestinal disorders among people with sleep disturbances: a population based study. Mayo Clin. Proc. 2004, 79:1501-1506.
486. Venero C., Tilling T., Hermans-Borgmeyer I., Schmidt R., Schachner M., Sandi C. Chronic stress induces opposite changes in the mRNA expression of the cell adhesion molecules NCAM and L1. Neuroscience 2002, 115:1211-1219.
487. Verdejo-Garcia A., Lopez-Torrecillas F., Calandre E.P., Delgado-Rodriguez A., Bechara A. Executive function and decision-making in women with fibromyalgia. Arch. Clin. Neuropsychol. 2009, 24:113-122.
488. Videbech P., Ravnkilde B. Hippocampal volume and depression: a meta-analysis of MRI studies. Am. J. Psychiatry 2004, 161:1957-1966.
489. Vitkovic L., Bockaert J., Jacque C. " Inflammatory" cytokines: neuromodulators in normal brain?. J. Neurochem. 2000, 74:457-471.
490. Vitkovic L., Konsman J.P., Bockaert J., Dantzer R., Homburger V., Jacque C. Cytokine signals propagate through the brain. Mol. Psychiatry 2000, 5:604-615.
491. Vogt B.A. Pain and emotion interactions in subregions of the cingulate gyrus. Nat. Rev. 2005, 6:533-544.
492. Volz H.P., Gaser C., Hager F., Rzanny R., Mentzel H.J., Kreitschmann-Andermahr I., Kaiser W.A., Sauer H. Brain activation during cognitive stimulation with the Wisconsin Card Sorting Test-a functional MRI study on healthy volunteers and schizophrenics. Psychiatry Res. 1997, 75:145-157.
493. Wager T.D., Rilling J.K., Smith E.E., Sokolik A., Casey K.L., Davidson R.J., Kosslyn S.M., Rose R.M., Cohen J.D. Placebo-induced changes in FMRI in the anticipation and experience of pain. Science 2004, 303:1162-1167.
494. Wager T.D., Jonides J., Reading S. Neuroimaging studies of shifting attention: a meta-analysis. Neuroimage 2004, 22:1679-1693.
495. Wang J., Korczykowski M., Rao H., Fan Y., Pluta J., Gur R.C., McEwen B.S., Detre J.A. Gender difference in neural response to psychological stress. Soc. Cogn. Affect. Neurosci. 2007, 2:227-239.
496. Wang J., Rao H., Wetmore G.S., Furlan P.M., Korczykowski M., Dinges D.F., Detre J.A. Perfusion functional MRI reveals cerebral blood flow pattern under psychological stress. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:17804-17809.
497. Weaver J.D., Huang M.H., Albert M., Harris T., Rowe J.W., Seeman T.E. Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology 2002, 59:371-378.
498. Weinryb R.M., Osterberg E., Blomquist L., Hultcrantz R., Krakau I., Asberg M. Psychological factors in irritable bowel syndrome: a population-based study of patients, non-patients and controls. Scand. J. Gastroenterol. 2003, 38:503-510.
499. Weis S., Hausmann M., Stoffers B., Sturm W. Dynamic changes in functional cerebral connectivity of spatial cognition during the menstrual cycle. Hum Brain Mapp 2010, 10.1002/hbm.21126.
500. Welgan P., Meshkinpour H., Beeler M. Effect of anger on colon motor and myoelectric activity in irritable bowel syndrome. Gastroenterology 1988, 94:1150-1156.
501. White P.D., Moorey S. Psychosomatic illnesses are not " all in the mind" J. Psychosom. Res. 1997, 42:329-332.
502. Whitehead W.E., Bosmajian L., Zonderman A.B., Costa P.T., Schuster M.M. Symptoms of psychologic distress associated with irritable bowel syndrome. Comparison of community and medical clinic samples. Gastroenterology 1988, 95:709-714.
503. Whitehead W.E., Cheskin L.J., Heller B.R., Robinson J.C., Crowell M.D., Benjamin C., Schuster M.M. Evidence for exacerbation of irritable bowel syndrome during menses. Gastroenterology 1990, 98:1485-1489.
504. Whitehead W.E., Palsson O., Jones K.R. Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications?. Gastroenterology 2002, 122:1140-1156.
505. Whitehead W.E., Palsson O.S. Is rectal pain sensitivity a biological marker for irritable bowel syndrome: psychological influences on pain perception. Gastroenterology 1998, 115:1263-1271.
506. Whorwell P.J., Houghton L.A., Taylor E.E., Maxton D.G. Physiological effects of emotion: assessment via hypnosis. Lancet 1992, 340:69-72.
507. Whorwell P.J., Prior A., Colgan S.M. Hypnotherapy in severe irritable bowel syndrome: further experience. Gut 1987, 28:423-425.
508. Whorwell P.J., Prior A., Faragher E.B. Controlled trial of hypnotherapy in the treatment of severe refractory irritable-bowel syndrome. Lancet 1984, 2:1232-1234.
509. Wiech K., Kalisch R., Weiskopf N., Pleger B., Stephan K.E., Dolan R.J. Anterolateral prefrontal cortex mediates the analgesic effect of expected and perceived control over pain. J. Neurosci. 2006, 26:11501-11509.
510. Wiech K., Ploner M., Tracey I. Neurocognitive aspects of pain perception. Trends Cogn. Sci. 2008, 12:306-313.
511. Wilber A.A., Southwood C.J., Sokoloff G., Steinmetz J.E., Wellman C.L. Neonatal maternal separation alters adult eyeblink conditioning and glucocorticoid receptor expression in the interpositus nucleus of the cerebellum. Dev. Neurobiol. 2007, 67:1751-1764.
512. Wilding J., Andrews B., Hejdenberg J. Relations between life difficulties, measures of working memory operation, and examination performance in a student sample. Memory (Hove, England) 2007, 15:57-62.
513. Wilson A., Longstreth G.F., Knight K., Wong J., Wade S., Chiou C.F., Barghout V., Frech F., Ofman J.J. Quality of life in managed care patients with irritable bowel syndrome. Manag. Care Interface 2004, 17:24-28. 34.
514. Wingenfeld K., Rullkoetter N., Mensebach C., Beblo T., Mertens M., Kreisel S., Toepper M., Driessen M., Woermann F.G. Neural correlates of the individual emotional Stroop in borderline personality disorder. Psychoneuroendocrinology 2009, 34:571-586.
515. Wolf O.T. HPA axis and memory. Best Pract. Res. Clin. Endocrinol. Metab. 2003, 17:287-299.
516. Wolf O.T., Convit A., McHugh P.F., Kandil E., Thorn E.L., De Santi S., McEwen B.S., de Leon M.J. Cortisol differentially affects memory in young and elderly men. Behav. Neurosci. 2001, 115:1002-1011.
517. Wolkowitz O.M., Reus V.I., Canick J., Levin B., Lupien S. Glucocorticoid medication, memory and steroid psychosis in medical illness. Ann. N. Y. Acad. Sci. 1997, 823:81-96.
518. Woodman C.L., Breen K., Russell N.J., Moss C., Fagerholm R., Yagla S.J., Summers R. The relationship between irritable bowel syndrome and psychiatric illness. Psychosomatics 1998, 39:45-54.
519. Woods D.L., Kishiyama M.M., Yund E.W., Herron T.J., Edwards B., Poliva O., Hink R.F., Reed B. Improving digit span assessment of short-term verbal memory. J. Clin. Exp. Neuropsychol. 2010, 4:1-11.
520. Woon F.L., Hedges D.W. Hippocampal and amygdala volumes in children and adults with childhood maltreatment-related posttraumatic stress disorder: a meta-analysis. Hippocampus 2008, 18:729-736.
521. Woon F.L., Sood S., Hedges D.W. Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: a meta-analysis. Prog. Neuropsychopharmacol. Biol. Psychiatry 2010, 34:1181-1188.
522. Wright C., Sacco R., Rundek T., Delman J., Rabbani L., Elkind M. Interleukin-6 is associated with cognitive function: the Northern Manhattan Study. J. Stroke Cerebrovasc. Dis. 2006, 15:34-38.
523. Wright R., Conrad C. Chronic stress leaves novelty-seeking behavior intact while impairing spatial recognition memory in the Y-maze. Stress Int. J. Biol. Stress 2005, 8:151-154.
524. Yamada K., Iida R., Miyamoto Y., Saito K., Sekikawa K., Seishima M., Nabeshima T. Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-alpha gene: implications for emotional behavior. J. Neuroimmunol. 2000, 111:131-138.
525. Yang H., Zhou Z., Liu Y., Ruan Z., Gong H., Luo Q., Lu Z. Gender difference in hemodynamic responses of prefrontal area to emotional stress by near-infrared spectroscopy. Behav. Brain Res. 2007, 178:172-176.
526. Yirmiya R., Winocur G., Goshen I. Brain interleukin-1 is involved in spatial memory and passive avoidance conditioning. Neurobiol. Learn. Mem. 2002, 78:379-389.
527. Yu T., Guo M., Garza J., Rendon S., Sun X.L., Zhang W., Lu X.Y. Cognitive and neural correlates of depression-like behaviour in socially defeated mice: an animal model of depression with cognitive dysfunction. Int. J. Neuropsychopharmacol. 2010, 14:1-15.
528. Zijdenbos I.L., de Wit N.J., van der Heijden G.J., Rubin G., Quartero A.O. Psychological treatments for the management of irritable bowel syndrome. Cochrane Database Syst. Rev. 2009, CD006442.
529. Zubieta J.K., Bueller J.A., Jackson L.R., Scott D.J., Xu Y., Koeppe R.A., Nichols T.E., Stohler C.S. Placebo effects mediated by endogenous opioid activity on mu-opioid receptors. J. Neurosci. 2005, 25:7754-7762.