Neurobehavioral alterations in developing transgenic mice expressing TNF-α in the brain

Brain, Behavior, and Immunity

Volumn 10, Issue 2, 1996, Pages 126-138

  Fiore, M ^a   Probert, L ^b   Kollias, G ^b   Akassoglou, K ^b   Alleva, E ^c   Aloe, L ^a  

^a CNR   (Italy)

^b HELLENIC PASTEUR INSTITUTE   (Greece)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONTROLLED STUDY; FEMALE; MALE; MEMORY; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0030174305     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1006/brbi.1996.0013     Document Type: Article

References (42)

1. Alleva, E., & Bignami, G. (1985). Development of mouse activity, stimulus reactivity, habituation, and response to amphetamine and scopolamine. Phisiol. Behav. 34, 519-523.
2. Alleva, E., Aloe, L., & Bigi, S. (1993). Un updated role for nerve growth factor in neurobehavioural regulation of adult vertebrates. Rev. Neurosc. 4, 41-62.
3. Aloe, L., Probert, L., Kollias, G., Bracci-Laudiero, L., Spillantini, M. G., & Levi-Montalcini, R. (1993). The synovium of transgenic arthritic mice expressing human tumor necrosis factor contains a high level of nerve growth factor. Growth Factors 9, 149-155.
4. Bernardini, R., Kamilaris, T. C., Calogero, A. E., Johnson, E. O., Gomez, M. T., Gold, P. W., & Chrousos, G. P. (1990). Interactions between tumor necrosis factor, hyphothalamic corticotropin-releasing hormone and adrenocorticotropin secretion in the rat. Endocrinology 126, 2871-2881.
5. Bianchi, M., Sacerdote, P., Ricciardi-Castagnoli, P., Mantegazza, P., & Panerai, P. E. (1992). Central effects of tumor necrosis factor α and interleukin-1α on nociceptive thresholds and spontaneous locomotor activity. Neurosc. Lett. 148, 76-80.
6. Bluthé, R. M., Dantzer, R., & Kelley, K. W. (1991). Interleukin-1 mediates behavioural but not metabolic effects of tumor necrosis factor alpha in mice. Eur. J. Pharmacol. 209, 281-283.
7. Breder, C. D., Tsujimoto, M., Terano, Y., Scott, D. W., & Saper, C. B. (1993). Distribution and characterization of tumor necrosis factor-α-like immunoreactivity in the murine central nervous system. J. Comp. Neurol. 337, 543-567.
8. Calamandrei, G., Valanzano, A., & Alleva, E. (1991). NGF and cholinergic control of behavior: Anticipation and enhancement of scopolamine effects in neonatal mice. Dev. Brain Res. 61, 237-224.
9. Calamandrei, G., & Alleva, E. (1995). Neuronal growth factors, neurotrophins and memory deficiency. Behav. Brain Res. 66, 129-132.
10. Cheng, B., Christakos, S., & Mattson, M. P. (1994). Tumor necrosis factors protect neurons against metabolic-exitocic insults and promote maintenance of calcium homeostasis. Neuron 12, 139-153.
11. Costall, B., Jones, B. J., Kelly, M. E., Naylor, R. J., & Tomkins, D. M. (1989). Exploration of mice in a black and white test box: Validation as a model of anxiety. Pharmacol. Biochem. Behav. 32, 777-785.
12. Crawley, J. N., & Goodwin, F. K. (1980). Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines. Pharmacol. Biochem. Behav. 13, 167-170.
13. Della Seta, D., De Acetis, L., Aloe, L., & Alleva, E. (1994). NGF effects on hot-plate behaviors in mice. Pharmacol. Biochem. Behav. 49, 701-705.
14. File, S. E. (1985). Models of anxiety. Br. J. Clin. Pract. 38, 15-20.
15. Fiore, M., Dell'Omo, G., Alleva, E., & Lipp, HP. (1996). A comparison of behavioural effects of prenatally administered oxazepam in mice exposed to open-fields in the laboratory and the real world. Psychopharmacology 122, 72-77.
16. Fischer, W., Victorin, K., Bjorklund, A., Williams, L. R., Varon, S., & Gage, F. H. (1987). Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature 329, 65-68.
17. Hattori, A., Iwasaki, S., Murase, K., Tsujimoto, M., Sato, M., Hayashi, K., & Kohno, M. (1994). Tumor necrosis factor is markedly synergistic with Interleukin 1 and interferon-gamma in stimulating the production of nerve growth factor in fibroblasts. FEBS Lett. 340, 177-180.
18. Keffer, J., Probert, L., Cazlaris, H., Georgopoulos, S., Kaslaris, E., Kioussis, D., & Kollias, G. (1991). Transgenic mice expressing human tumor necrosis factor, a predictive genetic model of arthritis. EMBO J. 10, 4025-4031.
19. Laviola, G., Renna, G., Bignami, G., & Cuomo, V. (1988). Ontogenetic and pharmacological dissociation of various components of locomotor activity and habituation in the rat. Int. J. Dev. Neurosci. 6, 431-438.
20. Levi-Montalcini, R. (1952). Effects of mouse tumor transplantation on the nervous system. Ann. N.Y. Acad. Sci, 55, 330-343.
21. Levi-Montalcini, R. (1987). The nerve growth factor 35 years later. Science 237, 1154-1162.
22. Levi-Montalcini, R., Aloe, L., & Alleva, E. (1990). A role for nerve growth factor in nervous, endocrine and immune systems. Prog. Neuroendocrinimmunol. 3, 1-10.
23. Lewin, G. L., & Mendell, L. M. (1993). Nerve growth factor and nociception. Trends Neurosci. 16, 353-359.
24. Mackintosh, J. H. (1981). Behaviour of the house mouse. Symp. Zool. Soc. London 47, 337-365.
25. Merrill, J. E. (1992). Tumor necrosis factor alpha, interleukin 1 and related cytokines in brain development: normal and pathological. Dev. Neurosci. 14, 1-10.
26. Miles, D. W., Happerfield, L. C., Naylor, M. S., Bobrow, L. C., Rubens, R. D., & Balkwill, F. S. (1994). Expression of tumor necrosis factor (TNF alpha) and its receptors in benign and malignant breast tissue. Int. J. Cancer 56, 777-782.
27. Minami, M., Kuraishi, Y., & Satho, M. (1991). Effects of kainic acid on messenger RNA levels of IL-I beta, IL-6, TNF alpha and LIF in the rat brain. Biochem. Biophys. Res. Commun. 176, 593-598.
28. Oliverio, A., Eleftheriou, B. E., & Bailey, D. W. (1973). Exploratory activity: genetic analysis of its modification by scopolamine and amphetamine. Physiol. Behav. 10, 893-899.
29. Olton, S. D., & Markowska, A. L. (1994). Memory and hippocampal function as target for neurotoxic substances. NeuroToxicology 15, 439-444.
30. Probert, L., Keffer, J., Corbella, P., Cazlaris, H., Patsavoudi, E., Stephens, S., Kaslaris, E., Kioussis, D., & Kollias, G. (1993). Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell-targeted human tumor necrosis factor transgenes. J. Immunol. 151, 1894-1906.
31. Probert, L., Akassoglou, K., Pasparakis, M., Kontogeorgos, G., & Kollias, G. (1995). Spontaneous inflammatory demyelinating disease in transgenic mice showing CNS-specific TNF-α expression. Proc. Natl. Acad. Sci. USA 92, 11294-11298.
32. Ricciardi-Castagnoli, P., Pirami, L., Righi, M., Sacerdote, P., Locatelli, V., Bianchi, M., Sassano, M., Valsasnini, P., Shammah, S., & Panerai, A. E. (1990). Cellular sources and effects of tumor necrosis factor-alpha on pituitary cells and in the central nervous system. Ann. N.Y. Acad. Sci. 594, 156-158.
33. Rothe, J., Gehr, G., Loetscher, H., & Lesslauer, W. (1992). Tumor necrosis factor receptors-structure and function. Immunol. Res. 11, 81-90.
34. Schall, T. J., Lewis, M., Koller, K. J., Lee, A., Rice, G. C., Wong, G. H. W., Gatanaga, T., Granger, G. A., Lentz, R., Raab, H., Kohr, W. J., & Goeddel, D. V. (1990). Molecular cloning and expression of a receptor for human necrosis factor. Cell 61, 61-370.
35. Spruijt, B. M., Van Hoof, J. A. R. A., & Gispen, W. H. (1992). Ethology and neurobiology of grooming behavior. Physiol. Rev. 72, 825-852.
36. Tancredi, V., D'Arcangelo, G., Grassi, F., Tarroni, P., Palmieri, G., Santoni, A., & Eusebi, F. (1992). Tumor necrosis factor alters synaptic transmission in rat hippocampal slices. Neurosci. Lett. 146, 176-178.
37. Tchelingerian, J-L., Vignais, L., & Jacque, C. (1994). TNF-α gene expression is induced in neurones after a hyppocampal lesion. NeuroReport 5, 585-588.
38. Theobald, C. M., & Goupillot, R. P. (1990). The analysis of repeated latency measure in behavioural studies. Anim. Behav. 40, 484-490.
39. Thoenen, H., & Barde, Y. A. (1980). Physiology of nerve growth factor. Physiol. Rev. 60, 1284-1335.
40. Vassalli, P. (1992). The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10, 411-452.
41. Vilcek, J., & Lee, T. H. (1991). Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J. Biol. Chem. 266, 7313-7316.
42. Wilcox, R. R. (1987). New statistical procedures for the social sciences. Erlbaum: Hillsdale, New Jersey.