Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome

Gut

Volumn 47, Issue 6, 2000, Pages 804-811

  Spiller, R C ^a   Jenkins, D ^a   Thornley, J P ^a   Hebden, J M ^a   Wright, T ^a   Skinner, M ^a   Neal, K R ^a  

^a NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Campylobacter; Enteroendocrine cell; Irritable bowel syndrome; T lymphocytes

Indexed keywords

ADULT; AGED; ARTICLE; CAMPYLOBACTER; CLINICAL ARTICLE; DYSENTERY; ENDOCRINE CELL; ENTERITIS; FEMALE; GRAM NEGATIVE INFECTION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INTESTINE MUCOSA PERMEABILITY; IRRITABLE COLON; MALE; PRIORITY JOURNAL; RECTUM BIOPSY; RECTUM MUCOSA; T LYMPHOCYTE;

ACUTE DISEASE; ADULT; AGED; ANTIGENS, CD; BIOPSY; CAMPYLOBACTER INFECTIONS; CELL COUNT; COLONIC DISEASES, FUNCTIONAL; ENTERITIS; ENTEROENDOCRINE CELLS; FEMALE; HUMANS; INTESTINAL MUCOSA; LIFE CHANGE EVENTS; LYMPHOCYTOSIS; MALE; MAST CELLS; MIDDLE AGED; PERMEABILITY; T-LYMPHOCYTES;

EID: 0033665517     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.47.6.804     Document Type: Article

References (50)

1. Symptoms of irritable bowel syndrome in a British urban community: Consulters and nonconsulters
2. The irritable colon syndrome
3. Prognosis in the irritable bowel syndrome: A 5 year prospective study
4. Prevalence of gastrointestinal symptoms six months after bacterial gastroenteritis and risk factors for development of the irritable bowel syndrome: Postal survey of patients
5. Irritable bowel syndrome - Post salmonella infection
6. Psychometric scores and persistence of irritable bowel after infectious diarrhoea
7. Irritable bowel syndrome could be an inflammatory disorder
8. The role of psychological and biological factors in postinfective gut dysfunction
9. Elevated cytokines, cytotoxic product and NK cells and pathogenesis of persistent acute-onset diarrhoea
10. Rectal mucosal adrenergic innervation and enterochromaffin cells in ulcerative colitis and irritable colon
11. Intestinal permeability and screening tests for coeliac disease
12. Intestinal permeability in children with Crohn's disease and coeliac disease
13. Identification of subgroups of functional gastrointestinal disorders
14. Guidelines for the initial biopsy diagnosis of suspected chronic idiopathic inflammatory bowel disease
15. Intestinal permeability and screening tests for coeliac disease
16. Intestinal permeability in children with Crohn's disease and coeliac disease
17. Increased risk of irritable bowel syndrome after bacterial gastroenteritis: Cohort study
18. Regional differences in concentrations of regulatory peptides in human colon mucosal biopsy
19. Mucosal protection through active intestinal secretion: Neural and paracrine modulation by 5-hydroxytryptamine
20. 5-Hydroxytryptamine agonists and antagonists in the modulation of gastrointestinal motility and sensation: Clinical implications
21. 5-Hydroxytryptamine release into human jejunum by cholera toxin
22. 5-HT2 and 5-HT3 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion in the rat
23. Enteropathy of coeliac disease in adults: Increased number of enterochromaffin cells in the duodenal mucosa
24. Motor dysfunction of the small bowel and colon in patients with the carcinoid syndrome and diarrhea
25. A 5HT3 antagonist corrects the postprandial colonic hypertonic response in carcinoid diarrhea
26. 5-Hydroxytryptamine and functional bowel disorders
27. Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: A pilot study
28. Selective 5-hydroxytryptamine type 3 receptor antagonism with ondansetron as treatment for diarrhea-predominant irritable bowel syndrome: A pilot study
29. Selective 5-hydroxytryptamine antagonism: A role in irritable bowel syndrome and functional dyspepsia?
30. Effect of alosetron on responses to colonic distension in patients with irritable bowel syndrome
31. Human distribution and release of a putative new gut hormone, peptide YY
32. Peptide YY augments postprandial small intestinal absorption in the conscious dog
33. Effects of peptide YY (PYY) on mouth to caecum intestinal transit time and on the rate of gastric emptying in healthy volunteers
34. Preliminary report: Role of peptide YY in defence against diarrhoea
35. Inflammatory bowel disease: Etiology and pathogenesis
36. CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease
37. Immunoepidemiology of intestinal helminth infections. 4. Immunopathology in trichuriasis: Lessons from the mouse model
38. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
39. Transforming growth factor-β in mucossal immunity and tolerance
40. Human intestinal epithelial cell-induced CD8+ T cell activation is mediated through CD8 and the activation of CD8-associated p56lck
41. CD4+ T cell downregulation in human intestinal mucosa: Evidence for intestinal tolerance to luminal bacterial antigens
42. T-lymphocyte modulation of intestinal muscle function in the Trichinella-infected rat
43. Increased levels of substance P in the myenteric plexus of Trichinella-infected rats
44. Human monocyte-derived macrophages infected with virulent Shigella flexneri in vitro undergo a rapid cytolytic event similar to oncosis but not apoptosis
45. Effect of Clostridium difficile toxin A on human intestinal epithelial cells: Induction of interleukin 8 production and apoptosis after cell detachment
46. Increased macrophage subset in inflammatory bowel disease: Apparent recruitment from peripheral blood monocytes
47. Gastrin secretion from primary cultures of rabbit antral G cells: Stimulation by inflammatory cytokines
48. Terminal ileal mucosal mast cells in irritable bowel syndrome
49. Value of simple screening tests for the diagnosis of chronic diarrhoea
50. Lymphocytic ('microscopic') colitis: A comparative histopathologic study with particular reference to collagenous colitis