Two distinct catalytic strategies in the hepatitis delta virus ribozyme cleavage reaction

Biochemistry

Volumn 50, Issue 44, 2011, Pages 9424-9433

  Golden, Barbara L ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CLEAVAGE REACTION; CLEAVAGE SITES; COVALENT STRUCTURES; CYCLIC PHOSPHATES; DIVALENT METAL ION; HEPATITIS DELTA VIRUS; HIGH IONIC STRENGTH; IN-LINE; LEAVING GROUPS; LEWIS ACID; MECHANISTIC ANALYSIS; METAL BINDING; MONOVALENT CATIONS; RIBOZYMES;

CATALYSIS; FUNCTIONAL GROUPS; IONIC STRENGTH; METAL IONS; METALS; NUCLEOPHILES; RNA; VIRUSES;

CRYSTAL STRUCTURE;

CYTOSINE; DIVALENT CATION; HYDROXYL GROUP; LEWIS ACID; MAGNESIUM; METAL ION; MONOVALENT CATION; NUCLEOPHILE; NUCLEOTIDE; PHOSPHATE; PROTON; RIBONUCLEASE P; RIBOZYME; SHORT HAIRPIN RNA; SINGLE STRANDED RNA;

ANOPHELES GAMBIAE; ARTICLE; CATALYSIS; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HEPATITIS DELTA VIRUS; HYBRID; HYDROGEN BOND; INTRON; IONIC STRENGTH; METAL BINDING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RNA BINDING; RNA CLEAVAGE; RNA STRUCTURE; TANDEM REPEAT;

ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYTOSINE NUCLEOTIDES; ENZYME STABILITY; HEPATITIS DELTA VIRUS; HUMANS; MAGNESIUM; MODELS, MOLECULAR; RIBONUCLEOPROTEIN, U1 SMALL NUCLEAR; RNA, CATALYTIC; RNA, VIRAL; SUBSTRATE SPECIFICITY;

HEPATITIS DELTA VIRUS;

EID: 80155186850     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201157t     Document Type: Article

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