-
1
-
-
0026711027
-
Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain
-
Yang, J., Usman, N., Chartland, P. & Cedergren, R. (1992). Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain. Biochemistry 31, 5005-5009.
-
(1992)
Biochemistry
, vol.31
, pp. 5005-5009
-
-
Yang, J.1
Usman, N.2
Chartland, P.3
Cedergren, R.4
-
2
-
-
0021013526
-
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
-
Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N. & Altman, S. (1983). The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 35, 849-875.
-
(1983)
Cell
, vol.35
, pp. 849-875
-
-
Guerrier-Takada, C.1
Gardiner, K.2
Marsh, T.3
Pace, N.4
Altman, S.5
-
3
-
-
0024340908
-
RNA catalytic properties of the minimum (-)sTRSV sequence
-
Hampel, A. & Tritz, R. (1989). RNA catalytic properties of the minimum (-)sTRSV sequence. Biochemistry 28, 4929-4933.
-
(1989)
Biochemistry
, vol.28
, pp. 4929-4933
-
-
Hampel, A.1
Tritz, R.2
-
4
-
-
0024364094
-
Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting
-
McSwiggen, J.A. & Cech, T.R. (1989). Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting. Science 244, 679-683.
-
(1989)
Science
, vol.244
, pp. 679-683
-
-
McSwiggen, J.A.1
Cech, T.R.2
-
5
-
-
0022649937
-
The intervening sequence RNA of Tetrahymena is an enzyme
-
Zaug, A.J. & Cech, T.R. (1986). The intervening sequence RNA of Tetrahymena is an enzyme. Science 231, 470-475.
-
(1986)
Science
, vol.231
, pp. 470-475
-
-
Zaug, A.J.1
Cech, T.R.2
-
6
-
-
0022975535
-
The Tetrahymena ribozyme acts like an RNA restriction endonuclease
-
Zaug, A.J., Been, M.D. & Cech, T.R. (1986). The Tetrahymena ribozyme acts like an RNA restriction endonuclease. Nature 324, 429-433.
-
(1986)
Nature
, vol.324
, pp. 429-433
-
-
Zaug, A.J.1
Been, M.D.2
Cech, T.R.3
-
7
-
-
0025265468
-
Substrate sequence effects on 'hammerhead' RNA catalytic efficiency
-
Fedor, M.J. & Uhlenbeck, O.C. (1990). Substrate sequence effects on 'hammerhead' RNA catalytic efficiency. Proc. Natl Acad. Sci. USA 87, 1668-1672.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 1668-1672
-
-
Fedor, M.J.1
Uhlenbeck, O.C.2
-
8
-
-
0023221419
-
A small catalytic oligoribonucleotide
-
Uhlenbeck, O.C. (1987). A small catalytic oligoribonucleotide. Nature 328, 596-600.
-
(1987)
Nature
, vol.328
, pp. 596-600
-
-
Uhlenbeck, O.C.1
-
9
-
-
0029690789
-
The role of metal ions in ribozymes
-
Sigel, H. & Sigel, A., eds Marcel Dekker, N.Y.
-
Pyle, A.M. (1996). The role of metal ions in ribozymes. In Metal Ions in Biological Systems, Vol 32 (Sigel, H. & Sigel, A., eds) pp. 479-520, Marcel Dekker, N.Y.
-
(1996)
Metal Ions in Biological Systems
, vol.32
, pp. 479-520
-
-
Pyle, A.M.1
-
10
-
-
0027389356
-
Self-cleaving catalytic RNA
-
Long, D. & Uhlenbeck, O. (1993). Self-cleaving catalytic RNA. FASEB J. 30, 25-30.
-
(1993)
FASEB J.
, vol.30
, pp. 25-30
-
-
Long, D.1
Uhlenbeck, O.2
-
11
-
-
0027184481
-
A general two-metal-ion mechanism for catalytic RNA
-
Steitz, T.A. & Steitz, J.A. (1993). A general two-metal-ion mechanism for catalytic RNA. Proc. Natl Acad. Sci. USA 90, 6498-6502.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 6498-6502
-
-
Steitz, T.A.1
Steitz, J.A.2
-
12
-
-
0000604820
-
Ribonuclease H activation by inert transition metal complexes. Mechanistic probes for metallocofactors: Insights on the metallobiochemisty of divalent magnesium ion
-
Jou, R. & Cowan, J.A. (1991). Ribonuclease H activation by inert transition metal complexes. Mechanistic probes for metallocofactors: insights on the metallobiochemisty of divalent magnesium ion. J. Am. Chem. Soc. 113, 6685-6686.
-
(1991)
J. Am. Chem. Soc.
, vol.113
, pp. 6685-6686
-
-
Jou, R.1
Cowan, J.A.2
-
13
-
-
0001143268
-
Evaluation of the free energy profile for ribonuclease H metal-promoted catalysis of phosphate ester hydrolysis. Use of inert chromium complexes to evaluate hydrogen bonding and electrostatic contributions to transition state stabilization
-
Black, C.B., Foster, M. & Cowan, J.A. (1996). Evaluation of the free energy profile for ribonuclease H metal-promoted catalysis of phosphate ester hydrolysis. Use of inert chromium complexes to evaluate hydrogen bonding and electrostatic contributions to transition state stabilization. J. Biol. Inorg. Chem. 1, 500-506.
-
(1996)
J. Biol. Inorg. Chem.
, vol.1
, pp. 500-506
-
-
Black, C.B.1
Foster, M.2
Cowan, J.A.3
-
14
-
-
0031026873
-
Inert chromium and cobalt complexes as probes of magnesium dependent enzymes. Evaluation of the stoichiometry and mechanistic role of the essential metal cofactor in Escherichia coli exonuclease III
-
Black, C.B. & Cowan, J.A. (1997). Inert chromium and cobalt complexes as probes of magnesium dependent enzymes. Evaluation of the stoichiometry and mechanistic role of the essential metal cofactor in Escherichia coli exonuclease III. Eur J. Biochem. 243, 684-689.
-
(1997)
Eur J. Biochem.
, vol.243
, pp. 684-689
-
-
Black, C.B.1
Cowan, J.A.2
-
16
-
-
0028105270
-
Quantitative evaluation of electrostatic and hydrogen bonding contributions to metal cofactor binding to nucleic acids
-
Black, C.B. & Cowan, J.A. (1994). Quantitative evaluation of electrostatic and hydrogen bonding contributions to metal cofactor binding to nucleic acids. J. Am. Chem. Soc 116, 1174-1178.
-
(1994)
J. Am. Chem. Soc
, vol.116
, pp. 1174-1178
-
-
Black, C.B.1
Cowan, J.A.2
-
17
-
-
0026028020
-
2+ binding sites on e coli 5S rRNA. Implications for activity
-
2+ binding sites on E coli 5S rRNA. Implications for activity. J. Am. Chem. Soc, 113, 673-675.
-
(1991)
J. Am. Chem. Soc
, vol.113
, pp. 673-675
-
-
Reid, S.S.1
Cowan, J.A.2
-
19
-
-
0022425387
-
Structural basis for stabilization of Z-DNA by cobalt hexaammine and magnesium cations
-
Gessner, R.V., Quigley, G.J., Wang, A.H.-J., van der Marel, G.A., van Boom, J.H. & Rich, A. (1985). Structural basis for stabilization of Z-DNA by cobalt hexaammine and magnesium cations. Biochemistry 24, 237-240.
-
(1985)
Biochemistry
, vol.24
, pp. 237-240
-
-
Gessner, R.V.1
Quigley, G.J.2
Wang, A.H.-J.3
Van Der Marel, G.A.4
Van Boom, J.H.5
Rich, A.6
-
20
-
-
0024363293
-
The molecular structure of the left-handed Z-DNA double helix at 1.0-.ANG. atomic resolution. Geometry, conformation, and ionic interactions of d(CGCGCG)
-
Gessner, R.V., Frederick, C.A., Quigley, G.J., Rich, A. & Wang, A.H.-J. (1989). The molecular structure of the left-handed Z-DNA double helix at 1.0-.ANG. atomic resolution. Geometry, conformation, and ionic interactions of d(CGCGCG). J. Biol. Chem. 264, 7921-7935.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 7921-7935
-
-
Gessner, R.V.1
Frederick, C.A.2
Quigley, G.J.3
Rich, A.4
Wang, A.H.-J.5
-
21
-
-
0027473887
-
Ionic requirements for RNA binding, cleavage and ligation by the hairpin ribozyme
-
Chowrira, B., Berzal-Herranz, A. & Burke, J. (1993). Ionic requirements for RNA binding, cleavage and ligation by the hairpin ribozyme. Biochemistry 32, 1088-1095.
-
(1993)
Biochemistry
, vol.32
, pp. 1088-1095
-
-
Chowrira, B.1
Berzal-Herranz, A.2
Burke, J.3
-
22
-
-
0027247579
-
Metal coordination sites that contribute to structure and catalysis in the group I intron from Tetrahymena
-
Christian, E.L & Yarus, M. (1993). Metal coordination sites that contribute to structure and catalysis in the group I intron from Tetrahymena. Biochemistry 32, 4475-4480.
-
(1993)
Biochemistry
, vol.32
, pp. 4475-4480
-
-
Christian, E.L.1
Yarus, M.2
-
23
-
-
0025821094
-
Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and magnesium binding
-
Koizumi, M. & Ohtsuka, E. (1991). Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and magnesium binding. Biochemistry 30, 5145-5150.
-
(1991)
Biochemistry
, vol.30
, pp. 5145-5150
-
-
Koizumi, M.1
Ohtsuka, E.2
-
24
-
-
0029583249
-
Hammerhead ribozymemediated cleavage of a substrate analog containing an intemucleotidic bridging 5′-phosphorothioate: Implications for the cleavage mechanism and the catalytic role of the metal cofactor
-
Kuimelis, R.G. & McLaughlin, LW. (1995). Hammerhead ribozymemediated cleavage of a substrate analog containing an intemucleotidic bridging 5′-phosphorothioate: implications for the cleavage mechanism and the catalytic role of the metal cofactor. J. Am. Chem. Soc. 117, 11019-11020.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 11019-11020
-
-
Kuimelis, R.G.1
McLaughlin, L.W.2
-
25
-
-
0025998488
-
Role of divalent metal ions in the hammerhead RNA cleavage reaction
-
Dahm, S.C. & Uhlenbeck, O.C. (1991). Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry 30, 9464-9469.
-
(1991)
Biochemistry
, vol.30
, pp. 9464-9469
-
-
Dahm, S.C.1
Uhlenbeck, O.C.2
-
26
-
-
0026027594
-
Nuclear magnetic resonance studies of the hammerhead ribozyme domain. Secondary structure formation and magnesium ion dependence
-
Heus, H.A. & Pardi, A. (1991). Nuclear magnetic resonance studies of the hammerhead ribozyme domain. Secondary structure formation and magnesium ion dependence. J. Mol. Biol. 217, 113-124.
-
(1991)
J. Mol. Biol.
, vol.217
, pp. 113-124
-
-
Heus, H.A.1
Pardi, A.2
-
27
-
-
0025771210
-
Ribozyme-catalyzed and nonenzymic reactions of phosphate diesters: Rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom
-
Herschlag, D., Piccirilli, J.A. & Cech, T.R. (1991). Ribozyme-catalyzed and nonenzymic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom. Biochemistry 30, 4844-4854.
-
(1991)
Biochemistry
, vol.30
, pp. 4844-4854
-
-
Herschlag, D.1
Piccirilli, J.A.2
Cech, T.R.3
-
28
-
-
0027398505
-
Metal ion catalysis in the Tetrahymena ribozyme reaction
-
Piccirilli, JA, Vyle, J.S., Caruthers, M.H. & Cech, T.R. (1993). Metal ion catalysis in the Tetrahymena ribozyme reaction. Nature 361, 85-88.
-
(1993)
Nature
, vol.361
, pp. 85-88
-
-
Piccirilli, J.A.1
Vyle, J.S.2
Caruthers, M.H.3
Cech, T.R.4
-
29
-
-
0024966814
-
Effects of substrate structure on the kinetics of circle opening reactions of the self-splicing intervening sequence from Tetrahymena thermophila: Evidence for substrate and magnesium binding interactions
-
Sugimoto, N., Tomka, M., Kierzek, R., Bevilacqua P.C. & Turner, D.H. (1989). Effects of substrate structure on the kinetics of circle opening reactions of the self-splicing intervening sequence from Tetrahymena thermophila: evidence for substrate and magnesium binding interactions. Nucleic Acids Res. 17, 355-371.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 355-371
-
-
Sugimoto, N.1
Tomka, M.2
Kierzek, R.3
Bevilacqua, P.C.4
Turner, D.H.5
-
30
-
-
0026047343
-
Binding and cleavage of nucleic acids by the hairpin ribozyme
-
Chowrira, B.M. & Burke, J.M. (1991). Binding and cleavage of nucleic acids by the hairpin ribozyme. Biochemistry 30, 8518-8522.
-
(1991)
Biochemistry
, vol.30
, pp. 8518-8522
-
-
Chowrira, B.M.1
Burke, J.M.2
-
31
-
-
0029556755
-
Rational redesign of a metal-dependent nuclease. Engineering the active site of magnesiumdependent ribonuclease H to form an active 'metal-independent' enzyme
-
Casareno, R.L.B., Li, D. & Cowan, J.A. (1995). Rational redesign of a metal-dependent nuclease. Engineering the active site of magnesiumdependent ribonuclease H to form an active 'metal-independent' enzyme. J. Am. Chem. Soc. 117, 11011-11012.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 11011-11012
-
-
Casareno, R.L.B.1
Li, D.2
Cowan, J.A.3
-
32
-
-
0025021952
-
'Hairpin' catalytic RNA model: Evidence for helixes and sequence requirement for substrate RNA
-
Hampel, A., Tritz, R., Hicks, M. & Cruz, P. (1990). 'Hairpin' catalytic RNA model: evidence for helixes and sequence requirement for substrate RNA. Nucleic Acids Res. 18, 299-304.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 299-304
-
-
Hampel, A.1
Tritz, R.2
Hicks, M.3
Cruz, P.4
-
33
-
-
0023651444
-
Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates
-
Milligan, J.F., Groebe, D.R., Witherell, G.W. & Uhlenbeck, O.C. (1987). Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates. Nucleic Acids Res. 15, 8783-8798.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 8783-8798
-
-
Milligan, J.F.1
Groebe, D.R.2
Witherell, G.W.3
Uhlenbeck, O.C.4
-
34
-
-
0028225004
-
Mutagenesis of the hairpin ribozyme
-
Anderson, P., Monforte, J., Tritz, R., Nesbitt, S., Hearst, J. & Hampel, A. (1994). Mutagenesis of the hairpin ribozyme. Nucleic Acids Res. 22, 1096-1100.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 1096-1100
-
-
Anderson, P.1
Monforte, J.2
Tritz, R.3
Nesbitt, S.4
Hearst, J.5
Hampel, A.6
|