A genomewide search for ribozymes reveals an HDV-like sequence in the human CPEB3 gene

Science

Volumn 313, Issue 5794, 2006, Pages 1788-1792

  Salehi Ashtiani, Kourosh ^a,b   Lupták, Andrej ^a   Litovchick, Alexander ^a   Szostak, Jack W ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; CELLS; GENES; RNA;

MAMMALS; POLYADENYLATION; RIBOZYMES;

GENETIC ENGINEERING;

MESSENGER RNA; RIBOZYME; TRANSCRIPTOME;

EVOLUTION; GENE; RNA;

ARTICLE; CPEB3 GENE; GENE; GENE CONTROL; GENE MAPPING; GENE SEQUENCE; HEPATITIS DELTA VIRUS; HUMAN; NONHUMAN; PRIORITY JOURNAL; RNA STRUCTURE;

BASE PAIRING; BASE SEQUENCE; CATALYSIS; CATIONS, DIVALENT; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; EXPRESSED SEQUENCE TAGS; GENOME, HUMAN; GENOMIC LIBRARY; HEPATITIS DELTA VIRUS; HUMANS; HYDROGEN-ION CONCENTRATION; INTRONS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PHOSPHORYLATION; RNA, CATALYTIC; RNA-BINDING PROTEINS;

HEPATITIS DELTA VIRUS; MAMMALIA;

EID: 33749034196     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1129308     Document Type: Article

References (36)

1. R. F. Gesteland, T. R. Cech, J. F. Atkins, Eds., The RNA World: The Nature of Modern RNA Suggests a Prebiotic RNA (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, ed. 3, 2006).
2. M. J. Fedor, J. R. Williamson, Nat Rev. Mol. Cell Biol. 6, 399 (2005).
3. D. S. Wilson, J. W. Szostak, Annu. Rev. Biochem. 68, 611 (1999).
4. W. C. Winkler, A. Nahvi, A. Roth, J. A. Collins, R. R. Breaker, Nature 428, 281 (2004).
5. A. Teixeira et al., Nature 432, 526 (2004).
6. A. C. Forster, R. H. Symons, Cell 50, 9 (1987).
7. A. Hampel, R. Tritz, Biochemistry 28, 4929 (1989).
8. M. Y. Kuo, L. Sharmeen, G. Dinter-Gottlieb, J. Taylor, J. Virol. 62, 4439 (1988).
9. B. J. Seville, R. A. Collins, Cell 61, 685 (1990).
10. H. Nielsen, E. Westhof, S. Johansen, Science 309, 1584 (2005).
11. Materials and methods are available as supporting material on Science Online.
12. S. L. Daubendiek, E. T. Kool. Nat. Biotechnol. 15, 273 (1997).
13. S. F. Altschul, W. Gish, W. Miller, E. W. Myers, D. J. Lipman, J. Mol. Biol. 215, 403 (1990).
14. A. S. Hinrichs et al., 'Nucleic Acids Res. 34, D590 (2006).
15. J. B. Murray, A. A. Seyhan, N. G. Walter, J. M. Burke, W. G. Scott, Chem. Biol. 5, 587 (1998).
16. K. Salehi-Ashtiani, J. W. Szostak, Nature 414, 82 (2001).
17. L. Sharmeen, M. Y. Kuo, G. Dinter-Gottlieb, J. Taylor, J. Virol. 62, 2674 (1988).
18. A. R. Ferré-D'Amaré, K. Zhou, J. A. Doudna, Nature 395, 567 (1998).
19. T. S. Wadkins, A. T. Perrotta, A. R. Ferre-D'Amare, J. A. Doudna, M. D. Been, RNA 5, 720 (1999).
20. S. Nakano, D. M. Chadalavada, P. C. Bevilacqua, Science 287, 1493 (2000).
21. S. R. Das, J. A. Piccirilli, Nat. Chem. Biol. 1, 45 (2005).
22. A. Ke, K. Zhou, F. Ding, J. H. Cate, J. A. Doudna, Nature 429, 201 (2004).
23. A. T. Perrotta, I. Shih, M. D. Been, Science 286, 123 (1999).
24. E. L. Christian, M. Yarus, J. Mol. Biol. 228, 743 (1992).
25. N. S. Prabhu, G. Dinter-Gottlieb, P. A. Gottlieb, Nucleic Acids Res. 25, 5119 (1997).
26. S. P. Rosenstein, M. D. Been, Biochemistry 35, 11403 (1996).
27. A. Nehdi, J. P. Perreault, Nucleic Acids Res. 34, 584 (2006).
28. M. Legiewicz, A. Wichlacz, B. Brzezicha, J. Ciesiolka, Nucleic Acids Res. 34, 1270 (2006).
29. R. Brazas, D. Ganem, Science 274, 90 (1996).
30. D. S. Ucker, K. R. Yamamoto, J. Biol. Chem. 259, 7416 (1984).
31. Y. S. Huang, J. D. Richter, Curr. Opin. Cell Biol. 16, 308 (2004).
32. T. Nagase et al., DNA Res. 6, 63 (1999).
33. M. Theis, K. Si, E. R. Kandel, Proc. Natl. Acad. Sci. U.S.A. 100, 9602 (2003).
34. K. Si et al., Cell 115, 893 (2003).
35. K. Si, S. Lindquist, E. R. Kandel, Cell 115, 879 (2003).
36. We thank L. Yen, G. Short, E. Meisami, E. Weiler, D. Treco, R. Bruckner, S. Schalm, J. Dennis, L. Davidoff, J. Ichida, J. Carothers, R. Larralde, and members of the Szostak laboratory for useful discussions and/or critical comments on the manuscript; P. Svec, D. Levin, and L. Almeida for administrative and laboratory support; and the Massachusetts General Hospital DNA core facility. Supported by NIH grants GM53936 and HL66678 to J.W.S. and the Howard Hughes Medical Institute.