-
1
-
-
10744227590
-
Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens
-
Aandahl, E. M., J. Michaelsson, W. J. Moretto, F. M. Hecht, and D. F. Nixon. 2004. Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. J. Virol. 78:2454-2459.
-
(2004)
J. Virol.
, vol.78
, pp. 2454-2459
-
-
Aandahl, E.M.1
Michaelsson, J.2
Moretto, W.J.3
Hecht, F.M.4
Nixon, D.F.5
-
2
-
-
77949416171
-
Gut mucosal FOXP3+ regulatory CD4+ T cells and nonregulatory CD4+ T cells are differentially affected by simian immunodeficiency virus infection in rhesus macaques
-
Allers, K., et al. 2010. Gut mucosal FOXP3+ regulatory CD4+ T cells and nonregulatory CD4+ T cells are differentially affected by simian immunodeficiency virus infection in rhesus macaques. J. Virol. 84:3259-3269.
-
(2010)
J. Virol.
, vol.84
, pp. 3259-3269
-
-
Allers, K.1
-
3
-
-
17444407451
-
The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients
-
Andersson, J., et al. 2005. The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. J. Immunol. 174:3143-3147.
-
(2005)
J. Immunol.
, vol.174
, pp. 3143-3147
-
-
Andersson, J.1
-
4
-
-
51449088613
-
Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals
-
Antons, A. K., R. Wang, S. A. Kalams, and D. Unutmaz. 2008. Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals. PLoS One 3:e2952.
-
(2008)
PLoS One
, vol.3
-
-
Antons, A.K.1
Wang, R.2
Kalams, S.A.3
Unutmaz, D.4
-
5
-
-
0035413350
-
CD4+CD25high regulatory cells in human peripheral blood
-
Baecher-Allan, C., J. A. Brown, G. J. Freeman, and D. A. Hafler. 2001. CD4+CD25high regulatory cells in human peripheral blood. J. Immunol. 167:1245-1253.
-
(2001)
J. Immunol.
, vol.167
, pp. 1245-1253
-
-
Baecher-Allan, C.1
Brown, J.A.2
Freeman, G.J.3
Hafler, D.A.4
-
6
-
-
33846781424
-
Peripheral CD4 loss of regulatory T cells is associated with persistent viraemia in chronic HIV infection
-
Baker, C. A., et al. 2007. Peripheral CD4 loss of regulatory T cells is associated with persistent viraemia in chronic HIV infection. Clin. Exp. Immunol. 147:533-539.
-
(2007)
Clin. Exp. Immunol.
, vol.147
, pp. 533-539
-
-
Baker, C.A.1
-
7
-
-
34748873441
-
Regulatory T cells and infection: a dangerous necessity
-
Belkaid, Y. 2007. Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 7:875-888.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 875-888
-
-
Belkaid, Y.1
-
8
-
-
16844369607
-
Natural regulatory T cells in infectious disease
-
Belkaid, Y., and B. T. Rouse. 2005. Natural regulatory T cells in infectious disease. Nat. Immunol. 6:353-360.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 353-360
-
-
Belkaid, Y.1
Rouse, B.T.2
-
9
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C. L., et al. 2001. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27:20-21.
-
(2001)
Nat. Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
10
-
-
35448968815
-
Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection
-
Boasso, A., et al. 2007. Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection. J. Virol. 81:11593-11603.
-
(2007)
J. Virol.
, vol.81
, pp. 11593-11603
-
-
Boasso, A.1
-
11
-
-
53449093632
-
Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
-
Brenchley, J. M., et al. 2008. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112:2826-2835.
-
(2008)
Blood
, vol.112
, pp. 2826-2835
-
-
Brenchley, J.M.1
-
12
-
-
33645924682
-
HIV disease: fallout from a mucosal catastrophe? Nat
-
Brenchley, J. M., D. A. Price, and D. C. Douek. 2006. HIV disease: fallout from a mucosal catastrophe? Nat. Immunol. 7:235-239.
-
(2006)
Immunol
, vol.7
, pp. 235-239
-
-
Brenchley, J.M.1
Price, D.A.2
Douek, D.C.3
-
13
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
Brenchley, J. M., et al. 2006. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 12:1365-1371.
-
(2006)
Nat. Med.
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
-
14
-
-
4644342929
-
CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
-
Brenchley, J. M., et al. 2004. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 200:749-759.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 749-759
-
-
Brenchley, J.M.1
-
15
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M. E., et al. 2001. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27:68-73.
-
(2001)
Nat. Genet.
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
-
16
-
-
0028589592
-
Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection
-
Carini, C., M. F. McLane, K. H. Mayer, and M. Essex. 1994. Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection. Eur. J. Immunol. 24:2927-2934.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 2927-2934
-
-
Carini, C.1
McLane, M.F.2
Mayer, K.H.3
Essex, M.4
-
17
-
-
50149097478
-
Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation
-
Chase, A. J., H. C. Yang, H. Zhang, J. N. Blankson, and R. F. Siliciano. 2008. Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation. J. Virol. 82:8307-8315.
-
(2008)
J. Virol.
, vol.82
, pp. 8307-8315
-
-
Chase, A.J.1
Yang, H.C.2
Zhang, H.3
Blankson, J.N.4
Siliciano, R.F.5
-
18
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T. A., et al. 2000. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106:R75-R81.
-
(2000)
J. Clin. Invest.
, vol.106
-
-
Chatila, T.A.1
-
19
-
-
3843056825
-
Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load
-
Deeks, S. G., et al. 2004. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Blood 104:942-947.
-
(2004)
Blood
, vol.104
, pp. 942-947
-
-
Deeks, S.G.1
-
20
-
-
34548689151
-
Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy
-
Deeks, S. G., and B. D. Walker. 2007. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 27:406-416.
-
(2007)
Immunity
, vol.27
, pp. 406-416
-
-
Deeks, S.G.1
Walker, B.D.2
-
21
-
-
75649117427
-
CD4+CD25+/hiCD127lo phenotype does not accurately identify regulatory T cells in all populations of HIV-infected persons
-
del Pozo-Balado, M. M., M. Leal, G. Mendez-Lagares, and Y. M. Pacheco. 2010. CD4+CD25+/hiCD127lo phenotype does not accurately identify regulatory T cells in all populations of HIV-infected persons. J. Infect. Dis. 201:331-335.
-
(2010)
J. Infect. Dis.
, vol.201
, pp. 331-335
-
-
del Pozo-Balado, M.M.1
Leal, M.2
Mendez-Lagares, G.3
Pacheco, Y.M.4
-
22
-
-
79952294178
-
Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points
-
Dietze, K. K., et al. 2011. Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points. Proc. Natl. Acad. Sci. U. S. A. 108:2420-2425.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 2420-2425
-
-
Dietze, K.K.1
-
23
-
-
45949112196
-
CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection
-
Dunham, R. M., et al. 2008. CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection. J. Immunol. 180:5582-5592.
-
(2008)
J. Immunol.
, vol.180
, pp. 5582-5592
-
-
Dunham, R.M.1
-
24
-
-
15444363618
-
Depletion of regulatory T cells in HIV infection is associated with immune activation
-
Eggena, M. P., et al. 2005. Depletion of regulatory T cells in HIV infection is associated with immune activation. J. Immunol. 174:4407-4414.
-
(2005)
J. Immunol.
, vol.174
, pp. 4407-4414
-
-
Eggena, M.P.1
-
25
-
-
79955384228
-
Innate and adaptive immune responses both contribute to pathological CD4 T cell activation in HIV-1 infected Ugandans
-
Eller, M. A., et al. 2011. Innate and adaptive immune responses both contribute to pathological CD4 T cell activation in HIV-1 infected Ugandans. PLoS One 6:e18779.
-
(2011)
PLoS One
, vol.6
-
-
Eller, M.A.1
-
26
-
-
43949124825
-
HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control
-
Emu, B., et al. 2008. HLA class I-restricted T-cell responses may contribute to the control of human immunodeficiency virus infection, but such responses are not always necessary for long-term virus control. J. Virol. 82:5398-5407.
-
(2008)
J. Virol.
, vol.82
, pp. 5398-5407
-
-
Emu, B.1
-
27
-
-
33750320502
-
Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART
-
Epple, H.-J., et al. 2006. Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 108:3072-3078.
-
(2006)
Blood
, vol.108
, pp. 3072-3078
-
-
Epple, H.-J.1
-
28
-
-
77958083540
-
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
-
Estes, J. D., et al. 2010. Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections. PLoS Pathog. 6:e1001052.
-
(2010)
PLoS Pathog
, vol.6
-
-
Estes, J.D.1
-
29
-
-
33144476838
-
Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection
-
Estes, J. D., et al. 2006. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J. Infect. Dis. 193:703-712.
-
(2006)
J. Infect. Dis.
, vol.193
, pp. 703-712
-
-
Estes, J.D.1
-
30
-
-
33846785628
-
Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection
-
Estes, J. D., et al. 2007. Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. J. Infect. Dis. 195:551-561.
-
(2007)
J. Infect. Dis.
, vol.195
, pp. 551-561
-
-
Estes, J.D.1
-
31
-
-
77952977625
-
Tryptophan catabolism by indoleamine 2 3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV Dis
-
Favre, D., et al. 2010. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV Dis. Sci. Transl. Med. 2:32ra36.
-
(2010)
Sci. Transl. Med.
, vol.2
, Issue.32
-
-
Favre, D.1
-
32
-
-
41349101159
-
Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response?
-
Fazekas de St Groth, B., and A. L. Landay. 2008. Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response? AIDS 22:671-683.
-
(2008)
AIDS
, vol.22
, pp. 671-683
-
-
Fazekas de St Groth, B.1
Landay, A.L.2
-
33
-
-
65449126294
-
Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control
-
Ferre, A. L., et al. 2009. Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. Blood 113:3978-3989.
-
(2009)
Blood
, vol.113
, pp. 3978-3989
-
-
Ferre, A.L.1
-
34
-
-
77957944425
-
HIV controllers with HLA-DRB1*13 and HLADQB1* 06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses
-
Ferre, A. L., et al. 2010. HIV controllers with HLA-DRB1*13 and HLADQB1* 06 alleles have strong, polyfunctional mucosal CD4+ T-cell responses. J. Virol. 84:11020-11029.
-
(2010)
J. Virol.
, vol.84
, pp. 11020-11029
-
-
Ferre, A.L.1
-
35
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J. D., M. A. Gavin, and A. Y. Rudensky. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4:330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
36
-
-
0038434099
-
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
-
Gambineri, E., T. R. Torgerson, and H. D. Ochs. 2003. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr. Opin. Rheumatol. 15:430-435.
-
(2003)
Curr. Opin. Rheumatol.
, vol.15
, pp. 430-435
-
-
Gambineri, E.1
Torgerson, T.R.2
Ochs, H.D.3
-
37
-
-
13944258421
-
Early antiretroviral therapy for simian immunodeficiency virus infection leads to mucosal CD4+ T-cell restoration and enhanced gene expression regulating mucosal repair and regeneration
-
George, M. D., E. Reay, S. Sankaran, and S. Dandekar. 2005. Early antiretroviral therapy for simian immunodeficiency virus infection leads to mucosal CD4+ T-cell restoration and enhanced gene expression regulating mucosal repair and regeneration. J. Virol. 79:2709-2719.
-
(2005)
J. Virol.
, vol.79
, pp. 2709-2719
-
-
George, M.D.1
Reay, E.2
Sankaran, S.3
Dandekar, S.4
-
38
-
-
0014792798
-
Cell interactions in the induction of tolerance: the role of thymic lymphocytes
-
Gershon, R. K., and K. Kondo. 1970. Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology 18:723-737.
-
(1970)
Immunology
, vol.18
, pp. 723-737
-
-
Gershon, R.K.1
Kondo, K.2
-
39
-
-
0015172562
-
Infectious immunological tolerance
-
Gershon, R. K., and K. Kondo. 1971. Infectious immunological tolerance. Immunology 21:903-914.
-
(1971)
Immunology
, vol.21
, pp. 903-914
-
-
Gershon, R.K.1
Kondo, K.2
-
40
-
-
0032955651
-
Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage
-
Giorgi, J. V., et al. 1999. Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J. Infect. Dis. 179:859-870.
-
(1999)
J. Infect. Dis.
, vol.179
, pp. 859-870
-
-
Giorgi, J.V.1
-
41
-
-
78149471644
-
Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals
-
Gordon, S. N., et al. 2010. Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals. J. Immunol. 185:5169-5179.
-
(2010)
J. Immunol.
, vol.185
, pp. 5169-5179
-
-
Gordon, S.N.1
-
42
-
-
77951060733
-
OX40 is required for regulatory T cell-mediated control of colitis
-
Griseri, T., M. Asquith, C. Thompson, and F. Powrie. 2010. OX40 is required for regulatory T cell-mediated control of colitis. J. Exp. Med. 207:699-709.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 699-709
-
-
Griseri, T.1
Asquith, M.2
Thompson, C.3
Powrie, F.4
-
43
-
-
0142092389
-
Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
-
Guadalupe, M., et al. 2003. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 77:11708-11717.
-
(2003)
J. Virol.
, vol.77
, pp. 11708-11717
-
-
Guadalupe, M.1
-
44
-
-
25844482131
-
Perils at mucosal front lines for HIV and SIV and their hosts
-
Haase, A. T. 2005. Perils at mucosal front lines for HIV and SIV and their hosts. Nat. Rev. Immunol. 5:783-792.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 783-792
-
-
Haase, A.T.1
-
45
-
-
62549154975
-
Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis
-
Holmes, D., Q. Jiang, L. Zhang, and L. Su. 2008. Foxp3 and Treg cells in HIV-1 infection and immuno-pathogenesis. Immunol. Res. 41:248-266.
-
(2008)
Immunol. Res.
, vol.41
, pp. 248-266
-
-
Holmes, D.1
Jiang, Q.2
Zhang, L.3
Su, L.4
-
46
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
47
-
-
79551649723
-
A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers
-
Hunt, P. W., et al. 2011. A low T regulatory cell response may contribute to both viral control and generalized immune activation in HIV controllers. PLoS One 6:e15924.
-
(2011)
PLoS One
, vol.6
-
-
Hunt, P.W.1
-
48
-
-
33746377279
-
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
-
Izcue, A., J. L. Coombes, and F. Powrie. 2006. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunol. Rev. 212:256-271.
-
(2006)
Immunol. Rev.
, vol.212
, pp. 256-271
-
-
Izcue, A.1
Coombes, J.L.2
Powrie, F.3
-
49
-
-
33747228472
-
Regulatory T cells generated during cytomegalovirus in vitro stimulation of mononuclear cells from HIVinfected individuals on HAART correlate with decreased lymphocyte proliferation
-
Jesser, R. D., S. Li, and A. Weinberg. 2006. Regulatory T cells generated during cytomegalovirus in vitro stimulation of mononuclear cells from HIVinfected individuals on HAART correlate with decreased lymphocyte proliferation. Virology 352:408-417.
-
(2006)
Virology
, vol.352
, pp. 408-417
-
-
Jesser, R.D.1
Li, S.2
Weinberg, A.3
-
50
-
-
61349156886
-
HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression
-
Ji, J., and M. W. Cloyd. 2009. HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression. Int. Immunol. 21:283-294.
-
(2009)
Int. Immunol.
, vol.21
, pp. 283-294
-
-
Ji, J.1
Cloyd, M.W.2
-
51
-
-
68249136806
-
The decrease of regulatory T cells correlates with excessive activation and apoptosis of CD8(+) T cells in HIV-1-infected typical progressors, but not in long-term non-progressors
-
Jiao, Y., et al. 2009. The decrease of regulatory T cells correlates with excessive activation and apoptosis of CD8(+) T cells in HIV-1-infected typical progressors, but not in long-term non-progressors. Immunology 128(Suppl. 1):e366-e375.
-
(2009)
Immunology
, vol.128
, Issue.SUPPL. 1
-
-
Jiao, Y.1
-
52
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., T. Cox, S. A. Yasayko, and F. Ramsdell. 2003. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4:337-342.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
53
-
-
33847667461
-
Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals
-
Kinter, A., et al. 2007. Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals. Proc. Natl. Acad. Sci. U. S. A. 104:3390-3395.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 3390-3395
-
-
Kinter, A.1
-
54
-
-
3543098686
-
CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
-
Kinter, A. L., et al. 2004. CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J. Exp. Med. 200:331-343.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 331-343
-
-
Kinter, A.L.1
-
55
-
-
34247241493
-
CD25+ regulatory T cells isolated from HIVinfected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro
-
Kinter, A. L., et al. 2007. CD25+ regulatory T cells isolated from HIVinfected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro. AIDS Res. Hum. Retroviruses 23:438-450.
-
(2007)
AIDS Res. Hum. Retroviruses
, vol.23
, pp. 438-450
-
-
Kinter, A.L.1
-
56
-
-
32044462951
-
Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects
-
Krathwohl, M. D., T. W. Schacker, and J. L. Anderson. 2006. Abnormal presence of semimature dendritic cells that induce regulatory T cells in HIV-infected subjects. J. Infect. Dis. 193:494-504.
-
(2006)
J. Infect. Dis.
, vol.193
, pp. 494-504
-
-
Krathwohl, M.D.1
Schacker, T.W.2
Anderson, J.L.3
-
57
-
-
34548042128
-
Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal
-
Legrand, F. A., et al. 2006. Strong HIV-1-specific T cell responses in HIV-1-exposed uninfected infants and neonates revealed after regulatory T cell removal. PLoS One 1:e102.
-
(2006)
PLoS One
, vol.1
-
-
Legrand, F.A.1
-
58
-
-
0035806323
-
Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
Levings, M. K., R. Sangregorio, and M. G. Roncarolo. 2001. Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 193:1295-1302.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1295-1302
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
59
-
-
17844376742
-
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells
-
Li, Q., et al. 2005. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 434:1148-1152.
-
(2005)
Nature
, vol.434
, pp. 1148-1152
-
-
Li, Q.1
-
60
-
-
37349126294
-
Natural regulatory T cells and persistent viral infection
-
Li, S., E. J. Gowans, C. Chougnet, M. Plebanski, and U. Dittmer. 2008. Natural regulatory T cells and persistent viral infection. J. Virol. 82:21-30.
-
(2008)
J. Virol.
, vol.82
, pp. 21-30
-
-
Li, S.1
Gowans, E.J.2
Chougnet, C.3
Plebanski, M.4
Dittmer, U.5
-
61
-
-
44449110691
-
Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II
-
Liang, B., et al. 2008. Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II. J. Immunol. 180:5916-5926.
-
(2008)
J. Immunol.
, vol.180
, pp. 5916-5926
-
-
Liang, B.1
-
62
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
-
Liu, W., et al. 2006. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J. Exp. Med. 203:1701-1711.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
-
63
-
-
0030668834
-
Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the multicenter AIDS cohort study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression
-
Liu, Z., et al. 1997. Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the multicenter AIDS cohort study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J. Acquir. Immune Defic. Syndr. 16:83-92.
-
(1997)
J. Acquir. Immune Defic. Syndr.
, vol.16
, pp. 83-92
-
-
Liu, Z.1
-
64
-
-
17844374605
-
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
-
Mattapallil, J. J., et al. 2005. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 434:1093-1097.
-
(2005)
Nature
, vol.434
, pp. 1093-1097
-
-
Mattapallil, J.J.1
-
65
-
-
1842581857
-
Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
-
Misra, N., J. Bayry, S. Lacroix-Desmazes, M. D. Kazatchkine, and S. V. Kaveri. 2004. Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells. J. Immunol. 172:4676-4680.
-
(2004)
J. Immunol.
, vol.172
, pp. 4676-4680
-
-
Misra, N.1
Bayry, J.2
Lacroix-Desmazes, S.3
Kazatchkine, M.D.4
Kaveri, S.V.5
-
66
-
-
79956339815
-
Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism
-
Moreno-Fernandez, M. E., C. M. Rueda, L. K. Rusie, and C. A. Chougnet. 2011. Regulatory T cells control HIV replication in activated T cells through a cAMP-dependent mechanism. Blood 117:5372-5380.
-
(2011)
Blood
, vol.117
, pp. 5372-5380
-
-
Moreno-Fernandez, M.E.1
Rueda, C.M.2
Rusie, L.K.3
Chougnet, C.A.4
-
67
-
-
72849144975
-
Human regulatory T cells are targets for human immunodeficiency virus (HIV) infection, and their susceptibility differs depending on the HIV type 1 strain
-
Moreno-Fernandez, M. E., W. Zapata, J. T. Blackard, G. Franchini, and C. A. Chougnet. 2009. Human regulatory T cells are targets for human immunodeficiency virus (HIV) infection, and their susceptibility differs depending on the HIV type 1 strain. J. Virol. 83:12925-12933.
-
(2009)
J. Virol.
, vol.83
, pp. 12925-12933
-
-
Moreno-Fernandez, M.E.1
Zapata, W.2
Blackard, J.T.3
Franchini, G.4
Chougnet, C.A.5
-
68
-
-
77949908711
-
Expansion of FOXP3+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control
-
Nigam, P., et al. 2010. Expansion of FOXP3+ CD8 T cells with suppressive potential in colorectal mucosa following a pathogenic simian immunodeficiency virus infection correlates with diminished antiviral T cell response and viral control. J. Immunol. 184:1690-1701.
-
(2010)
J. Immunol.
, vol.184
, pp. 1690-1701
-
-
Nigam, P.1
-
69
-
-
33750310898
-
HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS
-
Nilsson, J., et al. 2006. HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood 108:3808-3817.
-
(2006)
Blood
, vol.108
, pp. 3808-3817
-
-
Nilsson, J.1
-
70
-
-
19344374571
-
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
-
Oswald-Richter, K., et al. 2004. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Biol. 2:E198.
-
(2004)
PLoS Biol
, vol.2
-
-
Oswald-Richter, K.1
-
71
-
-
57449111288
-
Level, phenotype and activation status of CD4+FoxP3+ regulatory T cells in patients chronically infected with human immunodeficiency virus and/or hepatitis C virus
-
Rallon, N. I., et al. 2009. Level, phenotype and activation status of CD4+FoxP3+ regulatory T cells in patients chronically infected with human immunodeficiency virus and/or hepatitis C virus. Clin. Exp. Immunol. 155:35-43.
-
(2009)
Clin. Exp. Immunol.
, vol.155
, pp. 35-43
-
-
Rallon, N.I.1
-
72
-
-
0035503984
-
Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats
-
Roederer, M. 2001. Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats. Cytometry 45:194-205.
-
(2001)
Cytometry
, vol.45
, pp. 194-205
-
-
Roederer, M.1
-
73
-
-
20844432429
-
Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level
-
Roncador, G., et al. 2005. Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level. Eur. J. Immunol. 35:1681-1691.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 1681-1691
-
-
Roncador, G.1
-
74
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25)
-
Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, and M. Toda. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of selftolerance causes various autoimmune diseases. J. Immunol. 155:1151-1164.
-
(1995)
Breakdown of a single mechanism of selftolerance causes various autoimmune diseases. J. Immunol.
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
75
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi, S., T. Yamaguchi, T. Nomura, and M. Ono. 2008. Regulatory T cells and immune tolerance. Cell 133:775-787.
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
76
-
-
73949113630
-
Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1
-
Salisch, N. C., et al. 2010. Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1. J. Immunol. 184:476-487.
-
(2010)
J. Immunol.
, vol.184
, pp. 476-487
-
-
Salisch, N.C.1
-
77
-
-
37349078686
-
Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration
-
Sankaran, S., et al. 2008. Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration. J. Virol. 82:538-545.
-
(2008)
J. Virol.
, vol.82
, pp. 538-545
-
-
Sankaran, S.1
-
78
-
-
78651396992
-
Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease
-
Schulze zur Wiesch, J., et al. 2011. Comprehensive analysis of frequency and phenotype of T regulatory cells in HIV infection: CD39 expression of FoxP3+ T regulatory cells correlates with progressive disease. J. Virol. 85:1287-1297.
-
(2011)
J. Virol.
, vol.85
, pp. 1287-1297
-
-
Schulze zur Wiesch, J.1
-
79
-
-
41649101126
-
Regulatory T cells in HIV infection: who's suppressing what? Curr
-
Seddiki, N., and A. D. Kelleher. 2008. Regulatory T cells in HIV infection: who's suppressing what? Curr. HIV/AIDS Rep. 5:20-26.
-
(2008)
HIV/AIDS Rep
, vol.5
, pp. 20-26
-
-
Seddiki, N.1
Kelleher, A.D.2
-
80
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
Seddiki, N., et al. 2006. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J. Exp. Med. 203:1693-1700.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1693-1700
-
-
Seddiki, N.1
-
81
-
-
33645510596
-
Persistence of naive CD45RA+ regulatory T cells in adult life
-
Seddiki, N., et al. 2006. Persistence of naive CD45RA+ regulatory T cells in adult life. Blood 107:2830-2838.
-
(2006)
Blood
, vol.107
, pp. 2830-2838
-
-
Seddiki, N.1
-
82
-
-
60749107237
-
Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease
-
Seddiki, N., et al. 2009. Proliferation of weakly suppressive regulatory CD4+ T cells is associated with over-active CD4+ T-cell responses in HIV-positive patients with mycobacterial immune restoration disease. Eur. J. Immunol. 39:391-403.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 391-403
-
-
Seddiki, N.1
-
83
-
-
67649873285
-
Mucosal immunity to HIV: a review of recent literature
-
Shacklett, B. L. 2008. Mucosal immunity to HIV: a review of recent literature. Curr. Opin. HIV AIDS 3:541-547.
-
(2008)
Curr. Opin. HIV AIDS
, vol.3
, pp. 541-547
-
-
Shacklett, B.L.1
-
84
-
-
77249100438
-
HIV infection and gut mucosal immune function: updates on pathogenesis with implications for management and intervention
-
Shacklett, B. L., and P. A. Anton. 2010. HIV infection and gut mucosal immune function: updates on pathogenesis with implications for management and intervention. Curr. Infect. Dis. Rep. 12:19-27.
-
(2010)
Curr. Infect. Dis. Rep.
, vol.12
, pp. 19-27
-
-
Shacklett, B.L.1
Anton, P.A.2
-
85
-
-
0038033158
-
Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection
-
Shacklett, B. L., et al. 2003. Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection. J. Virol. 77:5621-5631.
-
(2003)
J. Virol.
, vol.77
, pp. 5621-5631
-
-
Shacklett, B.L.1
-
86
-
-
65549136983
-
Mechanisms of foxp3+ T regulatory cell-mediated suppression
-
Shevach, E. M. 2009. Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 30:636-645.
-
(2009)
Immunity
, vol.30
, pp. 636-645
-
-
Shevach, E.M.1
-
87
-
-
0031925896
-
Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes
-
Smit-McBride, Z., J. J. Mattapallil, M. McChesney, D. Ferrick, and S. Dandekar. 1998. Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes. J. Virol. 72:6646-6656.
-
(1998)
J. Virol.
, vol.72
, pp. 6646-6656
-
-
Smit-McBride, Z.1
Mattapallil, J.J.2
McChesney, M.3
Ferrick, D.4
Dandekar, S.5
-
88
-
-
0037105617
-
CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load
-
Sousa, A. E., J. Carneiro, M. Meier-Schellersheim, Z. Grossman, and R. M. M. Victorino. 2002. CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load. J. Immunol. 169:3400-3406.
-
(2002)
J. Immunol.
, vol.169
, pp. 3400-3406
-
-
Sousa, A.E.1
Carneiro, J.2
Meier-Schellersheim, M.3
Grossman, Z.4
Victorino, R.M.M.5
-
89
-
-
77955399695
-
FOXP3 expression is upregulated in CD4+ T cells in progressive HIV-1 infection and is a marker of disease severity
-
Suchard, M. S., et al. 2010. FOXP3 expression is upregulated in CD4+ T cells in progressive HIV-1 infection and is a marker of disease severity. PLoS One 5:e11762.
-
(2010)
PLoS One
, vol.5
-
-
Suchard, M.S.1
-
90
-
-
0036086232
-
Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells
-
Taams, L. S., et al. 2002. Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells. Eur. J. Immunol. 32:1621-1630.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1621-1630
-
-
Taams, L.S.1
-
91
-
-
77949527332
-
Increased sensitivity of CD4+ T-effector cells to CD4+CD25+ Treg suppression compensates for reduced Treg number in asymptomatic HIV-1 infection
-
Thorborn, G., et al. 2010. Increased sensitivity of CD4+ T-effector cells to CD4+CD25+ Treg suppression compensates for reduced Treg number in asymptomatic HIV-1 infection. PLoS One 5:e9254.
-
(2010)
PLoS One
, vol.5
-
-
Thorborn, G.1
-
92
-
-
20644434609
-
Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients
-
Tsunemi, S., et al. 2005. Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients. AIDS 19:879-886.
-
(2005)
AIDS
, vol.19
, pp. 879-886
-
-
Tsunemi, S.1
-
93
-
-
42949162462
-
Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators
-
van Mierlo, G. J., et al. 2008. Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators. J. Immunol. 180:2747-2751.
-
(2008)
J. Immunol.
, vol.180
, pp. 2747-2751
-
-
van Mierlo, G.J.1
-
94
-
-
0032540418
-
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
-
Veazey, R. S., et al. 1998. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 280:427-431.
-
(1998)
Science
, vol.280
, pp. 427-431
-
-
Veazey, R.S.1
-
95
-
-
4644337357
-
Getting to the guts of HIV pathogenesis
-
Veazey, R. S., and A. A. Lackner. 2004. Getting to the guts of HIV pathogenesis. J. Exp. Med. 200:697-700.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 697-700
-
-
Veazey, R.S.1
Lackner, A.A.2
-
97
-
-
75449119312
-
Impact of changes in antigen level on CD38/PD-1 co-expression on HIV-specific CD8 T cells in chronic, untreated HIV-1 infection
-
Vollbrecht, T., et al. 2010. Impact of changes in antigen level on CD38/PD-1 co-expression on HIV-specific CD8 T cells in chronic, untreated HIV-1 infection. J. Med. Virol. 82:358-370.
-
(2010)
J. Med. Virol.
, vol.82
, pp. 358-370
-
-
Vollbrecht, T.1
-
98
-
-
8644280556
-
Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
-
Weiss, L., et al. 2004. Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 104:3249-3256.
-
(2004)
Blood
, vol.104
, pp. 3249-3256
-
-
Weiss, L.1
-
99
-
-
8344275995
-
Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells
-
Yagi, H., et al. 2004. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int. Immunol. 16: 1643-1656.
-
(2004)
Int. Immunol.
, vol.16
, pp. 1643-1656
-
-
Yagi, H.1
-
100
-
-
70149110489
-
High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40)
-
Zaunders, J. J., et al. 2009. High levels of human antigen-specific CD4+ T cells in peripheral blood revealed by stimulated coexpression of CD25 and CD134 (OX40). J. Immunol. 183:2827-2836.
-
(2009)
J. Immunol.
, vol.183
, pp. 2827-2836
-
-
Zaunders, J.J.1
-
101
-
-
54449093154
-
Relationship of frequency of CD4+CD25+Foxp3+ regulatory T cells with disease progression in antiretroviral-naive HIV-1 infected Chinese
-
Zhang, Z., et al. 2008. Relationship of frequency of CD4+CD25+Foxp3+ regulatory T cells with disease progression in antiretroviral-naive HIV-1 infected Chinese. Jpn. J. Infect. Dis. 61:391-392.
-
(2008)
Jpn. J. Infect. Dis.
, vol.61
, pp. 391-392
-
-
Zhang, Z.1
|