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Volumn 5, Issue 2, 2010, Pages

Increased sensitivity of CD4+ T-effector cells to CD4+CD25+ treg suppression compensates for reduced treg number in asymptomatic HIV-1 infection

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 17; TRANSCRIPTION FACTOR FOXP3; CD45 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA;

EID: 77949527332     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009254     Document Type: Article
Times cited : (25)

References (57)
  • 1
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: Friend or foe in immunity to infection?
    • Mills KHG (2004) Regulatory T cells: friend or foe in immunity to infection? Nat Rev Immunol 4: 841-55.
    • (2004) Nat Rev Immunol , vol.4 , pp. 841-855
    • Mills, K.H.G.1
  • 2
    • 34547214205 scopus 로고    scopus 로고
    • Regulatory T-cell immunotherapy for tolerance to self and foreign antigens in humans
    • Roncarolo BM, Battagalia M (2007) Regulatory T-cell immunotherapy for tolerance to self and foreign antigens in humans. Nature Reviews Immunology 7: 585-98.
    • (2007) Nature Reviews Immunology , vol.7 , pp. 585-598
    • Roncarolo, B.M.1    Battagalia, M.2
  • 3
    • 65549123867 scopus 로고    scopus 로고
    • Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?
    • Curotto de Lafaille MA, Lafaille JJ (2009) Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor? Immunity 30: 626-35.
    • (2009) Immunity , vol.30 , pp. 626-635
    • Curotto de Lafaille, M.A.1    Lafaille, J.J.2
  • 4
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet
    • Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, et al. (2001) The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 27: 20-1.
    • (2001) , vol.27 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3    Brunkow, M.E.4    Ferguson, P.J.5
  • 5
    • 40349089873 scopus 로고    scopus 로고
    • Couper KN, Blount DG, Wilson MS, Hafalla JC, Belkaid Y, et al. (2008) IL-10 from CD4CD25Foxp3CD127 Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection. PLoS Pathog 4: e1000004.
    • Couper KN, Blount DG, Wilson MS, Hafalla JC, Belkaid Y, et al. (2008) IL-10 from CD4CD25Foxp3CD127 Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection. PLoS Pathog 4: e1000004.
  • 6
    • 33746599842 scopus 로고    scopus 로고
    • Regulatory T cells in cancer
    • Beyer M, Schultze JL (2006) Regulatory T cells in cancer. Blood 108: 804-11.
    • (2006) Blood , vol.108 , pp. 804-811
    • Beyer, M.1    Schultze, J.L.2
  • 8
    • 10744227590 scopus 로고    scopus 로고
    • Human CD4+ CD25+ Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens
    • Aandahl EM, Michaelsson J, Moretto WJ, Hecht FM, Nixon DF (2004) Human CD4+ CD25+ Regulatory T Cells Control T-Cell Responses to Human Immunodeficiency Virus and Cytomegalovirus Antigens. J Viro 78: 2454-9.
    • (2004) J Viro , vol.78 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 10
    • 33144476838 scopus 로고    scopus 로고
    • Premature Induction of an Immunosuppressive Regulatory T Cell Response during Acute Simian Immunodeficiency Virus Infection
    • Estes JD, Li Q, Reynolds MR, Wietgrefe S, Duan L, et al. (2006) Premature Induction of an Immunosuppressive Regulatory T Cell Response during Acute Simian Immunodeficiency Virus Infection. The Journal of Infectious Diseases 193: 703-12.
    • (2006) The Journal of Infectious Diseases , vol.193 , pp. 703-712
    • Estes, J.D.1    Li, Q.2    Reynolds, M.R.3    Wietgrefe, S.4    Duan, L.5
  • 11
    • 34247632512 scopus 로고    scopus 로고
    • Simian Immunodeficiency Virus (SIV) Infection Influences the Level and Function of Regulatory T Cells in SIV-Infected Rhesus Macaques but Not SIV-Infected Sooty Mangabeys
    • Pereira LE, Villinger F, Onlamoon N, Bryan P, Cardona A, et al. (2007) Simian Immunodeficiency Virus (SIV) Infection Influences the Level and Function of Regulatory T Cells in SIV-Infected Rhesus Macaques but Not SIV-Infected Sooty Mangabeys. J Virol 81: 4445-56.
    • (2007) J Virol , vol.81 , pp. 4445-4456
    • Pereira, L.E.1    Villinger, F.2    Onlamoon, N.3    Bryan, P.4    Cardona, A.5
  • 12
    • 33847667461 scopus 로고    scopus 로고
    • Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals
    • Kinter A, McNally J, Riggin L, Jackson R, Roby G, et al. (2007) Suppression of HIV-specific T cell activity by lymph node CD25+ regulatory T cells from HIV-infected individuals. Proc Natl Acad Sci U S A 104: 3390-5.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3390-3395
    • Kinter, A.1    McNally, J.2    Riggin, L.3    Jackson, R.4    Roby, G.5
  • 13
    • 34247241493 scopus 로고    scopus 로고
    • CD25+ regulatory T cells isolated from HIV-infected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro
    • Kinter AL, Horak R, Sion M, Riggin L, McNally J, et al. (2007) CD25+ regulatory T cells isolated from HIV-infected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro. AIDS Res Hum Retroviruses 23: 438-50.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 438-450
    • Kinter, A.L.1    Horak, R.2    Sion, M.3    Riggin, L.4    McNally, J.5
  • 14
    • 8644280556 scopus 로고    scopus 로고
    • Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
    • Weiss L, Donkova-Petrini V, Caccavelli L, Balbo M, Carbonneil C, et al. (2004) Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 104: 3249-56.
    • (2004) Blood , vol.104 , pp. 3249-3256
    • Weiss, L.1    Donkova-Petrini, V.2    Caccavelli, L.3    Balbo, M.4    Carbonneil, C.5
  • 15
    • 33750310898 scopus 로고    scopus 로고
    • HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS
    • Nilsson J, Boasso A, Velilla PA, Zhang R, Vaccari M, et al. (2006) HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood 108: 3808-17.
    • (2006) Blood , vol.108 , pp. 3808-3817
    • Nilsson, J.1    Boasso, A.2    Velilla, P.A.3    Zhang, R.4    Vaccari, M.5
  • 16
    • 41349101159 scopus 로고    scopus 로고
    • Regulatory T cells in HIV infection: Pathogenic or protective participants in the immune response?
    • de St Groth BFL, Alan Lb (2008) Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response? AIDS 22: 671-83.
    • (2008) AIDS , vol.22 , pp. 671-683
    • de St1    Groth, B.F.L.2    Lb, A.3
  • 17
    • 0037105617 scopus 로고    scopus 로고
    • CD4 T Cell Depletion Is Linked Directly to Immune Activation in the Pathogenesis of HIV-1 and HIV-2 but Only Indirectly to the Viral Load
    • Sousa AE, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino RMM, et al. (2002) CD4 T Cell Depletion Is Linked Directly to Immune Activation in the Pathogenesis of HIV-1 and HIV-2 but Only Indirectly to the Viral Load. J Immunol 169: 3400-6.
    • (2002) J Immunol , vol.169 , pp. 3400-3406
    • Sousa, A.E.1    Carneiro, J.2    Meier-Schellersheim, M.3    Grossman, Z.4    Victorino, R.M.M.5
  • 18
    • 13944252473 scopus 로고    scopus 로고
    • T cell activation in HIV-seropositive Ugandans: Differential associations with viral load, CD4+ T cell depletion, and coinfection
    • Eggena MP, Vaccari M, Nilsson J, Shearer GM, Andersson J, et al. (2005) T cell activation in HIV-seropositive Ugandans: differential associations with viral load, CD4+ T cell depletion, and coinfection. J Infect Dis 191: 694-701.
    • (2005) J Infect Dis , vol.191 , pp. 694-701
    • Eggena, M.P.1    Vaccari, M.2    Nilsson, J.3    Shearer, G.M.4    Andersson, J.5
  • 19
    • 3543098686 scopus 로고    scopus 로고
    • Kinter AL, Hennessey M, Bell A, Kern S, Lin Y, et al. (2004) AS, CD25+CD4+ Regulatory T Cells from the Peripheral Blood of Asymptomatic HIV-infected Individuals Regulate CD4+ and CD8+ HIV-specific T Cell Immune Responses In Vitro and Are Associated with Favorable Clinical Markers of Disease Status. J Exp Med 200: 331-43.
    • Kinter AL, Hennessey M, Bell A, Kern S, Lin Y, et al. (2004) AS, CD25+CD4+ Regulatory T Cells from the Peripheral Blood of Asymptomatic HIV-infected Individuals Regulate CD4+ and CD8+ HIV-specific T Cell Immune Responses In Vitro and Are Associated with Favorable Clinical Markers of Disease Status. J Exp Med 200: 331-43.
  • 20
    • 20644434609 scopus 로고    scopus 로고
    • Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients
    • Tsunemi S, Iwasaki T, Imado T, Higasa S, Kakishita E, et al. (2005) Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients. AIDS 19: 879-86.
    • (2005) AIDS , vol.19 , pp. 879-886
    • Tsunemi, S.1    Iwasaki, T.2    Imado, T.3    Higasa, S.4    Kakishita, E.5
  • 21
    • 0037343278 scopus 로고    scopus 로고
    • Nonpathogenic SIV Infection of Sooty Mangabeys Is Characterized by Limited Bystander Immunopathology Despite Chronic High-Level Viremia
    • Silvestri G, Sodora DL, Koup RA, Paiardini M, O'Neil SP, et al. (2003) Nonpathogenic SIV Infection of Sooty Mangabeys Is Characterized by Limited Bystander Immunopathology Despite Chronic High-Level Viremia. Immunity 18: 441-52.
    • (2003) Immunity , vol.18 , pp. 441-452
    • Silvestri, G.1    Sodora, D.L.2    Koup, R.A.3    Paiardini, M.4    O'Neil, S.P.5
  • 22
    • 36349005400 scopus 로고    scopus 로고
    • Severe Depletion of CD4+ CD25+ Regulatory T Cells from the Intestinal Lamina Propria but Not Peripheral Blood or Lymph Nodes during Acute Simian Immunodeficiency Virus Infection
    • Chase AJ, Sedaghat AR, German JR, Gama L, Zink MC, et al. (2007) Severe Depletion of CD4+ CD25+ Regulatory T Cells from the Intestinal Lamina Propria but Not Peripheral Blood or Lymph Nodes during Acute Simian Immunodeficiency Virus Infection. J Virol 81: 12748-57.
    • (2007) J Virol , vol.81 , pp. 12748-12757
    • Chase, A.J.1    Sedaghat, A.R.2    German, J.R.3    Gama, L.4    Zink, M.C.5
  • 24
    • 0036883944 scopus 로고    scopus 로고
    • Inhibition of Human CD4+CD25+high Regulatory T Cell Function
    • Baecher-Allan C, Viglietta V, Hafler DA (2002) Inhibition of Human CD4+CD25+high Regulatory T Cell Function. J Immunol 169: 6210-7.
    • (2002) J Immunol , vol.169 , pp. 6210-6217
    • Baecher-Allan, C.1    Viglietta, V.2    Hafler, D.A.3
  • 27
    • 0036884096 scopus 로고    scopus 로고
    • Presence of HIV-1 Gag-Specific IFN-{gamma}+IL-2+ and CD28+IL-2+ CD4 T Cell Responses Is Associated with Nonprogression in HIV-1 Infection
    • Boaz MJ, Waters A, Murad S, Easterbrook PJ, Vyakarnam A (2002) Presence of HIV-1 Gag-Specific IFN-{gamma}+IL-2+ and CD28+IL-2+ CD4 T Cell Responses Is Associated with Nonprogression in HIV-1 Infection. J Immunol 169: 6376-85.
    • (2002) J Immunol , vol.169 , pp. 6376-6385
    • Boaz, M.J.1    Waters, A.2    Murad, S.3    Easterbrook, P.J.4    Vyakarnam, A.5
  • 28
    • 0347911962 scopus 로고    scopus 로고
    • HIV-1 Viremia Prevents the Establishment of Interleukin 2-producing HIV-specific Memory CD4+ T Cells Endowed with Proliferative Capacity
    • Younes S-A, Yassine-Diab B, Dumont AR, Boulassel M-R, Grossman Z, et al. (2003) HIV-1 Viremia Prevents the Establishment of Interleukin 2-producing HIV-specific Memory CD4+ T Cells Endowed with Proliferative Capacity. J Exp Med 198: 1909-22.
    • (2003) J Exp Med , vol.198 , pp. 1909-1922
    • Younes, S.-A.1    Yassine-Diab, B.2    Dumont, A.R.3    Boulassel, M.-R.4    Grossman, Z.5
  • 29
    • 55449111318 scopus 로고    scopus 로고
    • Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes
    • Lawson JT, Dayan C, Beyan H, Leslie RDG, Peakman M, et al. (2008) Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes. Clinical & Experimental Immunology 154: 353-9.
    • (2008) Clinical & Experimental Immunology , vol.154 , pp. 353-359
    • Lawson, J.T.1    Dayan, C.2    Beyan, H.3    Leslie, R.D.G.4    Peakman, M.5
  • 31
    • 44949174181 scopus 로고    scopus 로고
    • Natural regulatory T cells: Number and function are normal in the majority of patients with lupus nephritis
    • Yates AW, Mitchell P, Lechler RI, Lightston L, Lombardi G (2008) Natural regulatory T cells: number and function are normal in the majority of patients with lupus nephritis. Clin Exp Immunol 153: 44-55.
    • (2008) Clin Exp Immunol , vol.153 , pp. 44-55
    • Yates, A.W.1    Mitchell, P.2    Lechler, R.I.3    Lightston, L.4    Lombardi, G.5
  • 32
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, et al. (2006) Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-8.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5
  • 33
    • 43449135305 scopus 로고    scopus 로고
    • TGF-[bgr]-induced Foxp3 inhibits TH17 cell differentiation by antagonizing ROR[ggr]t function
    • Zhou L, Lopes JE, Chong MMW, Ivanov II, Min R, et al. (2008) TGF-[bgr]-induced Foxp3 inhibits TH17 cell differentiation by antagonizing ROR[ggr]t function. Nature 453: 236-40.
    • (2008) Nature , vol.453 , pp. 236-240
    • Zhou, L.1    Lopes, J.E.2    Chong, M.M.W.3    Ivanov II, M.R.4
  • 34
    • 36749081557 scopus 로고    scopus 로고
    • Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes
    • Evans HG, Suddason T, Jackson I, Taams LS, Lord GM (2007) Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes. Proceedings of the National Academy of Sciences 104: 17034-9.
    • (2007) Proceedings of the National Academy of Sciences , vol.104 , pp. 17034-17039
    • Evans, H.G.1    Suddason, T.2    Jackson, I.3    Taams, L.S.4    Lord, G.M.5
  • 36
    • 34247264460 scopus 로고    scopus 로고
    • Increased Interleukin-17 Production Both in Helper T Cell Subset Th17 And CD4-Negative T Cells in Human Immunodeficiency Virus Infection
    • Maek-A-Nantawat W, Buranapraditkun S, Klaewsongkram J, Ruxrungthum K (2007) Increased Interleukin-17 Production Both in Helper T Cell Subset Th17 And CD4-Negative T Cells in Human Immunodeficiency Virus Infection. Viral Immunology 20: 66-75.
    • (2007) Viral Immunology , vol.20 , pp. 66-75
    • Maek-A-Nantawat, W.1    Buranapraditkun, S.2    Klaewsongkram, J.3    Ruxrungthum, K.4
  • 37
    • 70350041508 scopus 로고    scopus 로고
    • Zhao Y, Yang J, Gao Y, Guo W (2010) Th17 Immunity in Patients with Allergic Asthma. International Archives of Allergy and Immunology 151: 297-307.
    • Zhao Y, Yang J, Gao Y, Guo W (2010) Th17 Immunity in Patients with Allergic Asthma. International Archives of Allergy and Immunology 151: 297-307.
  • 38
  • 39
    • 53449093632 scopus 로고    scopus 로고
    • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
    • Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, et al. (2008) Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 112: 2826-35.
    • (2008) Blood , vol.112 , pp. 2826-2835
    • Brenchley, J.M.1    Paiardini, M.2    Knox, K.S.3    Asher, A.I.4    Cervasi, B.5
  • 40
    • 43249093908 scopus 로고    scopus 로고
    • Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection
    • Ndhlovu LC, Chapman JM, Jha AR, Snyder-Cappione JF, Pagán M, et al. (2008) Suppression of HIV-1 plasma viral load below detection preserves IL-17 producing T cells in HIV-1 infection. AIDS 22: 990-2.
    • (2008) AIDS , vol.22 , pp. 990-992
    • Ndhlovu, L.C.1    Chapman, J.M.2    Jha, A.R.3    Snyder-Cappione, J.F.4    Pagán, M.5
  • 41
    • 61449115882 scopus 로고    scopus 로고
    • Favre D, Lederer S, Kanwar B, Ma Z-M, Proll S, et al. (2009) Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection. PLoS Pathog 5: e1000295.
    • Favre D, Lederer S, Kanwar B, Ma Z-M, Proll S, et al. (2009) Critical Loss of the Balance between Th17 and T Regulatory Cell Populations in Pathogenic SIV Infection. PLoS Pathog 5: e1000295.
  • 42
    • 77949507778 scopus 로고    scopus 로고
    • Trindade CJ, Heraud J-M, Cecchinato V, Laurence A, Brenchley J, et al. (2008) Preferential Loss of Th17 T-cells at Mucosal Sites Predicts AIDS Progression in Simian Immunodeficiency Virus-Infected Macaques. FASEB J 22: 852.7.
    • Trindade CJ, Heraud J-M, Cecchinato V, Laurence A, Brenchley J, et al. (2008) Preferential Loss of Th17 T-cells at Mucosal Sites Predicts AIDS Progression in Simian Immunodeficiency Virus-Infected Macaques. FASEB J 22: 852.7.
  • 43
    • 45449104669 scopus 로고    scopus 로고
    • Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques
    • Cecchinato CJT, Laurence A, Heraud JM, Brenchley JM, Ferrari MG, et al. (2008) Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. Mucosal Immunology 1: 279-88.
    • (2008) Mucosal Immunology , vol.1 , pp. 279-288
    • Cecchinato, C.J.T.1    Laurence, A.2    Heraud, J.M.3    Brenchley, J.M.4    Ferrari, M.G.5
  • 44
    • 9144232224 scopus 로고    scopus 로고
    • The role of activation-induced cell death in the differentiation of T-helper-cell subsets
    • Roberts A, Devadas S, Zhang X, Zhang L, Keegan A, et al. (2003) The role of activation-induced cell death in the differentiation of T-helper-cell subsets. Immunologic Research 28: 285-93.
    • (2003) Immunologic Research , vol.28 , pp. 285-293
    • Roberts, A.1    Devadas, S.2    Zhang, X.3    Zhang, L.4    Keegan, A.5
  • 45
    • 18544364477 scopus 로고    scopus 로고
    • Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase
    • Munn DH, Sharma MD, Lee JR, Jhaver KG, Johnson TS, et al. (2002) Potential Regulatory Function of Human Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase. Science 297: 1867-70.
    • (2002) Science , vol.297 , pp. 1867-1870
    • Munn, D.H.1    Sharma, M.D.2    Lee, J.R.3    Jhaver, K.G.4    Johnson, T.S.5
  • 46
    • 34547099820 scopus 로고    scopus 로고
    • Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death
    • Toscano GAB MA, Bianco GA, LLarregui JM, Croci DO, Correale J, et al. (2007) Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nature Immunology 8: 825-34.
    • (2007) Nature Immunology , vol.8 , pp. 825-834
    • Toscano1    GAB, M.A.2    Bianco, G.A.3    LLarregui, J.M.4    Croci, D.O.5    Correale, J.6
  • 47
    • 17444407451 scopus 로고    scopus 로고
    • Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients
    • Andersson J, Boasso A, Nilsson J, Zhang R, Shire NJ, et al. (2005) Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients. J Immunol 174: 3143-7.
    • (2005) J Immunol , vol.174 , pp. 3143-3147
    • Andersson, J.1    Boasso, A.2    Nilsson, J.3    Zhang, R.4    Shire, N.J.5
  • 48
    • 1642446585 scopus 로고    scopus 로고
    • Preferential replication of FIV in activated CD4+CD25+T cells independent of cellular proliferation
    • Joshi A, Vahlenkamp TW, Garg H, Tompkins WAF, Tompkins MB (2004) Preferential replication of FIV in activated CD4+CD25+T cells independent of cellular proliferation. Virology 321: 307-22.
    • (2004) Virology , vol.321 , pp. 307-322
    • Joshi, A.1    Vahlenkamp, T.W.2    Garg, H.3    Tompkins, W.A.F.4    Tompkins, M.B.5
  • 49
    • 40449092356 scopus 로고    scopus 로고
    • Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection
    • Antons AK, Wang R, Oswald-Richter K, Tseng M, Arendt CW, et al. (2008) Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection. J Immunol 180: 764-73.
    • (2008) J Immunol , vol.180 , pp. 764-773
    • Antons, A.K.1    Wang, R.2    Oswald-Richter, K.3    Tseng, M.4    Arendt, C.W.5
  • 50
    • 34447542374 scopus 로고    scopus 로고
    • FoxP3 Enhances HIV-1 Gene Expression by Modulating NF{kappa}B Occupancy at the Long Terminal Repeat in Human T Cells
    • Holmes D, Knudsen G, Mackey-Cushman S, Su L (2007) FoxP3 Enhances HIV-1 Gene Expression by Modulating NF{kappa}B Occupancy at the Long Terminal Repeat in Human T Cells. J Biol Chem 282: 15973-80.
    • (2007) J Biol Chem , vol.282 , pp. 15973-15980
    • Holmes, D.1    Knudsen, G.2    Mackey-Cushman, S.3    Su, L.4
  • 51
    • 19344374571 scopus 로고    scopus 로고
    • HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T-cells
    • Oswald-Richter K, Leelawong M, Unutmaz D (2004) HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T-cells. PLOS BIOLOGY 2: 0955-66.
    • (2004) PLOS BIOLOGY , vol.2 , pp. 0955-0966
    • Oswald-Richter, K.1    Leelawong, M.2    Unutmaz, D.3
  • 52
    • 33750320502 scopus 로고    scopus 로고
    • Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART
    • Epple H-J, Loddenkemper C, Kunkel D, Troger H, Maul J, et al. (2006) Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 108: 3072-8.
    • (2006) Blood , vol.108 , pp. 3072-3078
    • Epple, H.-J.1    Loddenkemper, C.2    Kunkel, D.3    Troger, H.4    Maul, J.5
  • 53
    • 69849103644 scopus 로고    scopus 로고
    • Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells
    • Becker C, Taube C, Bopp T, Becker C, Michel K, et al. (2009) Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells. Blood 114: 1263-9.
    • (2009) Blood , vol.114 , pp. 1263-1269
    • Becker, C.1    Taube, C.2    Bopp, T.3    Becker, C.4    Michel, K.5
  • 54
    • 61349156886 scopus 로고    scopus 로고
    • HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: An additional mechanism of immunosuppression
    • Ji J, Cloyd MW (2009) HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression. Int Immunol. dxn146.
    • (2009) Int Immunol
    • Ji, J.1    Cloyd, M.W.2
  • 55
    • 0027232141 scopus 로고
    • T-Cell Subsets in Health, Infectious Disease, and Idiopathic CD4+T Lymphocytopenia
    • Laurence J (1993) T-Cell Subsets in Health, Infectious Disease, and Idiopathic CD4+T Lymphocytopenia. Ann Intern Med 119: 55-62.
    • (1993) Ann Intern Med , vol.119 , pp. 55-62
    • Laurence, J.1
  • 56
    • 37349090747 scopus 로고    scopus 로고
    • WFDC1/ps20 Is a Novel Innate Immunomodulatory Signature Protein of Human Immunodeficiency Virus (HIV)-Permissive CD4+ CD45RO+ Memory T Cells That Promotes Infection by Upregulating CD54 Integrin Expression and Is Elevated in HIV Type 1 Infection
    • Alvarez R, Reading J, King DFL, Hayes M, Easterbrook P, et al. (2008) WFDC1/ps20 Is a Novel Innate Immunomodulatory Signature Protein of Human Immunodeficiency Virus (HIV)-Permissive CD4+ CD45RO+ Memory T Cells That Promotes Infection by Upregulating CD54 Integrin Expression and Is Elevated in HIV Type 1 Infection. J Virol 82: 471-86.
    • (2008) J Virol , vol.82 , pp. 471-486
    • Alvarez, R.1    Reading, J.2    King, D.F.L.3    Hayes, M.4    Easterbrook, P.5
  • 57
    • 0035943355 scopus 로고    scopus 로고
    • Selective Transcription and Modulation of Resting T Cell Activity by Preintegrated HIV DNA
    • Wu Y, Marsh JW (2001) Selective Transcription and Modulation of Resting T Cell Activity by Preintegrated HIV DNA. Science 293: 1503-6.
    • (2001) Science , vol.293 , pp. 1503-1506
    • Wu, Y.1    Marsh, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.