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Volumn 155, Issue 1, 2009, Pages 35-43

Level, phenotype and activation status of CD4+FoxP3+ regulatory T cells in patients chronically infected with human immunodeficiency virus and/or hepatitis C virus

Author keywords

Activation; FoxP3; HIV HCV co infection; Regulatory T cells

Indexed keywords

CD27 ANTIGEN; CD38 ANTIGEN; CD45RA ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

EID: 57449111288     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03797.x     Document Type: Article
Times cited : (44)

References (51)
  • 1
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary HIV type 1 syndrome
    • Koup RA, Safrit JT, Cao Y et al. Temporal association of cellular immune responses with the initial control of viremia in primary HIV type 1 syndrome. J Virol 1994 68 : 4650 5.
    • (1994) J Virol , vol.68 , pp. 4650-5
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3
  • 2
    • 0033524838 scopus 로고    scopus 로고
    • Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes
    • Schmitz J, Schmitz JE, Kuroda MJ et al. Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. Science 1999 283 : 857 60.
    • (1999) Science , vol.283 , pp. 857-60
    • Schmitz, J.1    Schmitz, J.E.2    Kuroda, M.J.3
  • 3
    • 10244225383 scopus 로고    scopus 로고
    • Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response
    • Missale G, Bertoni R, Lamonaca V et al. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J Clin Invest 1996 98 : 706 14.
    • (1996) J Clin Invest , vol.98 , pp. 706-14
    • Missale, G.1    Bertoni, R.2    Lamonaca, V.3
  • 4
    • 0035914925 scopus 로고    scopus 로고
    • Determinants of viral clearance and persistence during acute hepatitis C virus infection
    • Thimme R, Oldach D, Chang KM, Steiger C, Ray SC, Chisari FV. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med 2001 194 : 1395 406.
    • (2001) J Exp Med , vol.194 , pp. 1395-406
    • Thimme, R.1    Oldach, D.2    Chang, K.M.3    Steiger, C.4    Ray, S.C.5    Chisari, F.V.6
  • 5
    • 0034330698 scopus 로고    scopus 로고
    • Impaired function of circulating HIV-specific CD8+ T-cells in chronic HIV infection
    • Shankar P, Russo M, Harnisch B, Patterson M, Skolnik P, Lieberman J. Impaired function of circulating HIV-specific CD8+ T-cells in chronic HIV infection. Blood 2000 96 : 3094 101.
    • (2000) Blood , vol.96 , pp. 3094-101
    • Shankar, P.1    Russo, M.2    Harnisch, B.3    Patterson, M.4    Skolnik, P.5    Lieberman, J.6
  • 6
    • 0242413259 scopus 로고    scopus 로고
    • Phenotype and functional characteristics of HIV-specific cytotoxic CD8+ T-cells in chronically infected patients. Dual effects of highly active antiretroviral therapy
    • Benito JM, López M, Lozano S et al. Phenotype and functional characteristics of HIV-specific cytotoxic CD8+ T-cells in chronically infected patients. Dual effects of highly active antiretroviral therapy. J Acquir Immune Defic Syndr 2003 34 : 255 66.
    • (2003) J Acquir Immune Defic Syndr , vol.34 , pp. 255-66
    • Benito, J.M.1    López, M.2    Lozano, S.3
  • 7
    • 0037105567 scopus 로고    scopus 로고
    • Impaired effector function of hepatitis C virus-specific CD8-T cells in chronic hepatitis C virus infection
    • Wedemeyer H, He XS, Nascimbeni M et al. Impaired effector function of hepatitis C virus-specific CD8-T cells in chronic hepatitis C virus infection. J Immunol 2002 169 : 3447 58.
    • (2002) J Immunol , vol.169 , pp. 3447-58
    • Wedemeyer, H.1    He, X.S.2    Nascimbeni, M.3
  • 8
    • 0038374730 scopus 로고    scopus 로고
    • Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C
    • Ulsenheimer A, Gerlach JT, Gruener NH et al. Detection of functionally altered hepatitis C virus-specific CD4 T cells in acute and chronic hepatitis C. Hepatology 2003 37 : 1189 98.
    • (2003) Hepatology , vol.37 , pp. 1189-98
    • Ulsenheimer, A.1    Gerlach, J.T.2    Gruener, N.H.3
  • 9
    • 4344569076 scopus 로고    scopus 로고
    • The role of CD8+ T-cell response in HIV infection
    • Benito JM, López M, Soriano V. The role of CD8+ T-cell response in HIV infection. AIDS Rev 2004 6 : 79 88.
    • (2004) AIDS Rev , vol.6 , pp. 79-88
    • Benito, J.M.1    López, M.2    Soriano, V.3
  • 12
    • 12144287345 scopus 로고    scopus 로고
    • Functional impairment of CD8+ T cells by regulatory T cells during persistent retroviral infection
    • Dittmer U, He H, Messer RJ et al. Functional impairment of CD8+ T cells by regulatory T cells during persistent retroviral infection. Immunity 2004 20 : 293 303.
    • (2004) Immunity , vol.20 , pp. 293-303
    • Dittmer, U.1    He, H.2    Messer, R.J.3
  • 13
    • 7044247947 scopus 로고    scopus 로고
    • An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection
    • Cabrera R, Tu Z, Xu Y et al. An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. Hepatology 2004 40 : 1062 71.
    • (2004) Hepatology , vol.40 , pp. 1062-71
    • Cabrera, R.1    Tu, Z.2    Xu, Y.3
  • 14
    • 33747590748 scopus 로고    scopus 로고
    • The role of virus-induced regulatory T cells in immunopathology
    • Robertson S, Hasenkrug K. The role of virus-induced regulatory T cells in immunopathology. Springer Semin Immunopathol 2006 28 : 51 62.
    • (2006) Springer Semin Immunopathol , vol.28 , pp. 51-62
    • Robertson, S.1    Hasenkrug, K.2
  • 15
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 2001 193 : 1303 10.
    • (2001) J Exp Med , vol.193 , pp. 1303-10
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 16
    • 0035806290 scopus 로고    scopus 로고
    • Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
    • Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk AH. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001 193 : 1285 94.
    • (2001) J Exp Med , vol.193 , pp. 1285-94
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3    Tuettenberg, A.4    Knop, J.5    Enk, A.H.6
  • 17
    • 0035054606 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro
    • Stephens LA, Mottet C, Mason D, Powrie F. Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro. Eur J Immunol 2001 31 : 1247 54.
    • (2001) Eur J Immunol , vol.31 , pp. 1247-54
    • Stephens, L.A.1    Mottet, C.2    Mason, D.3    Powrie, F.4
  • 19
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • O'Garra A, Vieira P. Regulatory T cells and mechanisms of immune system control. Nat Med 2004 10 : 801 5.
    • (2004) Nat Med , vol.10 , pp. 801-5
    • O'Garra, A.1    Vieira, P.2
  • 20
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003 3 : 253 7.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-7
    • Bluestone, J.A.1    Abbas, A.K.2
  • 22
    • 10744227590 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory T cells control T-cell responses to HIV and cytomegalovirus antigens
    • Aandahl EM, Michaëlsson J, Moretto WJ, Hecht FM, Nixon DF. Human CD4+ CD25+ regulatory T cells control T-cell responses to HIV and cytomegalovirus antigens. J Virol 2004 78 : 2454 9.
    • (2004) J Virol , vol.78 , pp. 2454-9
    • Aandahl, E.M.1    Michaëlsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 23
    • 3543098686 scopus 로고    scopus 로고
    • CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
    • Kinter AL, Hennessey M, Bell A et al. CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 2004 200 : 331 43.
    • (2004) J Exp Med , vol.200 , pp. 331-43
    • Kinter, A.L.1    Hennessey, M.2    Bell, A.3
  • 24
    • 0345017746 scopus 로고    scopus 로고
    • Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection
    • Sugimoto K, Ikeda F, Stadanlick J, Nunes FA, Alter HJ, Chang KM. Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection. Hepatology 2003 38 : 1437 48.
    • (2003) Hepatology , vol.38 , pp. 1437-48
    • Sugimoto, K.1    Ikeda, F.2    Stadanlick, J.3    Nunes, F.A.4    Alter, H.J.5    Chang, K.M.6
  • 25
    • 8644280556 scopus 로고    scopus 로고
    • V-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
    • Weiss L, Donkova-Petrini V, Caccavelli L et al. V-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 2004 104 : 3249 56.
    • (2004) Blood , vol.104 , pp. 3249-56
    • Weiss, L.1    Donkova-Petrini, V.2    Caccavelli, L.3
  • 26
    • 20644434609 scopus 로고    scopus 로고
    • Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients
    • Tsunemi S, Iwasaki T, Imado T et al. Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients. AIDS 2005 19 : 879 86.
    • (2005) AIDS , vol.19 , pp. 879-86
    • Tsunemi, S.1    Iwasaki, T.2    Imado, T.3
  • 27
    • 19944370822 scopus 로고    scopus 로고
    • T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection
    • Boettler T, Spangenberg HC, Neumann-Haefelin C et al. T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. J Virol 2005 79 : 7860 7.
    • (2005) J Virol , vol.79 , pp. 7860-7
    • Boettler, T.1    Spangenberg, H.C.2    Neumann-Haefelin, C.3
  • 28
    • 1942456867 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis
    • Boyer O, Saadoun D, Abriol J et al. CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis. Blood 2004 103 : 3428 30.
    • (2004) Blood , vol.103 , pp. 3428-30
    • Boyer, O.1    Saadoun, D.2    Abriol, J.3
  • 29
    • 33751207432 scopus 로고    scopus 로고
    • Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells
    • Banham AH. Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells. Trends Immunol 2006 27 : 541 4.
    • (2006) Trends Immunol , vol.27 , pp. 541-4
    • Banham, A.H.1
  • 30
    • 15444363618 scopus 로고    scopus 로고
    • Depletion of regulatory T cells in HIV infection is associated with immune activation
    • Eggena MP, Barugahare B, Jones N et al. Depletion of regulatory T cells in HIV infection is associated with immune activation. J Immunol 2005 174 : 4407 14.
    • (2005) J Immunol , vol.174 , pp. 4407-14
    • Eggena, M.P.1    Barugahare, B.2    Jones, N.3
  • 32
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Treg cells
    • Liu W, Putnam AL, Xu-Yu Z et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Treg cells. J Exp Med 2006 203 : 1701 11.
    • (2006) J Exp Med , vol.203 , pp. 1701-11
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3
  • 33
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003 299 : 1057 61.
    • (2003) Science , vol.299 , pp. 1057-61
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 34
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003 4 : 330 6.
    • (2003) Nat Immunol , vol.4 , pp. 330-6
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 36
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 2003 4 : 337 42.
    • (2003) Nat Immunol , vol.4 , pp. 337-42
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 37
    • 33746675679 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells in antiretroviral-naive HIV patients
    • Montes M, Lewis DE, Sanchez C et al. Foxp3+ regulatory T cells in antiretroviral-naive HIV patients. AIDS 2006 20 : 1669 71.
    • (2006) AIDS , vol.20 , pp. 1669-71
    • Montes, M.1    Lewis, D.E.2    Sanchez, C.3
  • 38
    • 34247241493 scopus 로고    scopus 로고
    • CD25+ regulatory T cells isolated from HIV-infected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro
    • Kinter AL, Horak R, Sion M et al. CD25+ regulatory T cells isolated from HIV-infected individuals suppress the cytolytic and nonlytic antiviral activity of HIV-specific CD8+ T cells in vitro. AIDS Res Hum Retroviruses 2007 23 : 438 50.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 438-50
    • Kinter, A.L.1    Horak, R.2    Sion, M.3
  • 39
    • 22144470799 scopus 로고    scopus 로고
    • In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients
    • Sereti I, Imamichi H, Natarajan V et al. In vivo expansion of CD4CD45RO-CD25 T cells expressing foxP3 in IL-2-treated HIV-infected patients. J Clin Invest 2005 115 : 1839 47.
    • (2005) J Clin Invest , vol.115 , pp. 1839-47
    • Sereti, I.1    Imamichi, H.2    Natarajan, V.3
  • 40
    • 33744460201 scopus 로고    scopus 로고
    • Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C
    • Manigold T, Shin EC, Mizukoshi E et al. Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C. Blood 2006 107 : 4424 32.
    • (2006) Blood , vol.107 , pp. 4424-32
    • Manigold, T.1    Shin, E.C.2    Mizukoshi, E.3
  • 41
    • 38949128315 scopus 로고    scopus 로고
    • FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+CD8+ T cell activation levels in primary HIV-1 infection
    • Ndhlovu L, Loo C, Spotts G, Nixon D, Hecht F. FOXP3 expressing CD127lo CD4+ T cells inversely correlate with CD38+CD8+ T cell activation levels in primary HIV-1 infection. J Leukoc Biol 2008 83 : 254 62.
    • (2008) J Leukoc Biol , vol.83 , pp. 254-62
    • Ndhlovu, L.1    Loo, C.2    Spotts, G.3    Nixon, D.4    Hecht, F.5
  • 42
    • 33646182056 scopus 로고    scopus 로고
    • Are regulatory T-cells linked with aging?
    • Dejaco C, Duftner C, Schirmer M. Are regulatory T-cells linked with aging? Exp Gerontol 2006 41 : 339 45.
    • (2006) Exp Gerontol , vol.41 , pp. 339-45
    • Dejaco, C.1    Duftner, C.2    Schirmer, M.3
  • 43
    • 33750320502 scopus 로고    scopus 로고
    • Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART
    • Epple HJ, Loddenkemper C, Kunkel D et al. Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 2006 108 : 3072 8.
    • (2006) Blood , vol.108 , pp. 3072-8
    • Epple, H.J.1    Loddenkemper, C.2    Kunkel, D.3
  • 44
    • 53449092578 scopus 로고    scopus 로고
    • Foxp3+CD4+ Treg cells play an important role in acute HIV-1 infection in humanized rag2-/-(gamma)C-/- mice in vivo
    • Epub ahead of print F.*Sinistro A.*Ciaprini C.*et al.
    • Jiang Q, Zhang L, Wang R et al. Foxp3+CD4+ Treg cells play an important role in acute HIV-1 infection in humanized rag2-/-(gamma)C-/- mice in vivo. Blood 2008 112 : 2858 68 Epub ahead of print F, Sinistro A, Ciaprini C et al. Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels. Clin Exp Immunol 2006 144 : 188 96.
    • (2008) Blood , vol.112 , pp. 2858-68
    • Jiang, Q.1    Zhang, L.2    Wang, R.3
  • 45
    • 2142643603 scopus 로고    scopus 로고
    • CD4+ regulatory T cells in chronic viral infection
    • Hasenkrug K. CD4+ regulatory T cells in chronic viral infection. Novartis Found Symp 2003 252 : 194 9.
    • (2003) Novartis Found Symp , vol.252 , pp. 194-9
    • Hasenkrug, K.1
  • 46
    • 33745813929 scopus 로고    scopus 로고
    • Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
    • Seddiki N, Santner-Nanan B, Martinson J et al. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J Exp Med 2006 203 : 1693 700.
    • (2006) J Exp Med , vol.203 , pp. 1693-700
    • Seddiki, N.1    Santner-Nanan, B.2    Martinson, J.3
  • 47
    • 34247895580 scopus 로고    scopus 로고
    • Defining target antigens for CD25+ FOXP3 + IFN-gamma- regulatory T cells in chronic hepatitis C virus infection
    • Li S, Jones KL, Woollard DJ et al. Defining target antigens for CD25+ FOXP3 + IFN-gamma- regulatory T cells in chronic hepatitis C virus infection. Immunol Cell Biol 2007 85 : 197 204.
    • (2007) Immunol Cell Biol , vol.85 , pp. 197-204
    • Li, S.1    Jones, K.L.2    Woollard, D.J.3
  • 48
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006 12 : 1365 71.
    • (2006) Nat Med , vol.12 , pp. 1365-71
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3
  • 49
    • 0036932757 scopus 로고    scopus 로고
    • Differences in cellular activation and apoptosis in HIV-infected patients receiving protease inhibitors or nonnucleoside reverse transcriptase inhibitors
    • Benito JM, López M, Martín JC et al. Differences in cellular activation and apoptosis in HIV-infected patients receiving protease inhibitors or nonnucleoside reverse transcriptase inhibitors. AIDS Res Hum Retroviruses 2002 18 : 1379 88.
    • (2002) AIDS Res Hum Retroviruses , vol.18 , pp. 1379-88
    • Benito, J.M.1    López, M.2    Martín, J.C.3
  • 50
    • 19344374571 scopus 로고    scopus 로고
    • HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
    • Oswald-Richter K, Grill SM, Shariat N et al. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Biol 2004 2 : E198.
    • (2004) PLoS Biol , vol.2
    • Oswald-Richter, K.1    Grill, S.M.2    Shariat, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.