-
1
-
-
42749086113
-
-
Pabst R, Russell MW, Brandtzaeg P. Tissue distribution of lymphocytes and plasma cells and the role of the gut. Trends Immunol 2008; 29:206-208. This paper is a review of the mucosal immune system, including the official terminology adopted by the Society for Mucosal Immunology in 2007.
-
Pabst R, Russell MW, Brandtzaeg P. Tissue distribution of lymphocytes and plasma cells and the role of the gut. Trends Immunol 2008; 29:206-208. This paper is a review of the mucosal immune system, including the official terminology adopted by the Society for Mucosal Immunology in 2007.
-
-
-
-
2
-
-
67649889287
-
The gut is still the largest lymphoid organ in the body
-
in press
-
MacDonald TT. The gut is still the largest lymphoid organ in the body. Mucosal Immunology (in press).
-
Mucosal Immunology
-
-
MacDonald, T.T.1
-
3
-
-
36048968755
-
Understanding the benign nature of SIV infection in natural hosts
-
Silvestri G, Paiardini M, Pandrea I, et al. Understanding the benign nature of SIV infection in natural hosts. J Clin Invest 2007; 117:3148-3154.
-
(2007)
J Clin Invest
, vol.117
, pp. 3148-3154
-
-
Silvestri, G.1
Paiardini, M.2
Pandrea, I.3
-
4
-
-
34548689151
-
Human immunodeficiency virus controllers: Mechanisms of durable virus control in the absence of antiretroviral therapy
-
Deeks SG, Walker BD. Human immunodeficiency virus controllers: mechanisms of durable virus control in the absence of antiretroviral therapy. Immunity 2007; 27:406-416.
-
(2007)
Immunity
, vol.27
, pp. 406-416
-
-
Deeks, S.G.1
Walker, B.D.2
-
5
-
-
33646465596
-
Understanding the "lucky few": The conundrum of HIV-exposed, seronegative individuals
-
Shacklett BL. Understanding the "lucky few": the conundrum of HIV-exposed, seronegative individuals. Curr HIV/AIDS Rep 2006; 3:26-31.
-
(2006)
Curr HIV/AIDS Rep
, vol.3
, pp. 26-31
-
-
Shacklett, B.L.1
-
6
-
-
0036444413
-
Loss of ileal IgA+ plasma cells and of CD4+ lymphocytes in ileal Peyer's patches of vitamin A deficient rats
-
Bjersing JL, Telemo E, Dahlgren U, Hanson LA. Loss of ileal IgA+ plasma cells and of CD4+ lymphocytes in ileal Peyer's patches of vitamin A deficient rats. Clin Exp Immunol 2002; 130:404-408.
-
(2002)
Clin Exp Immunol
, vol.130
, pp. 404-408
-
-
Bjersing, J.L.1
Telemo, E.2
Dahlgren, U.3
Hanson, L.A.4
-
7
-
-
5644300399
-
Retinoic acid imprints gut-homing specificity on T cells
-
Iwata M, Hirakiyama A, Eshima Y, et al. Retinoic acid imprints gut-homing specificity on T cells. Immunity 2004; 21:527-538.
-
(2004)
Immunity
, vol.21
, pp. 527-538
-
-
Iwata, M.1
Hirakiyama, A.2
Eshima, Y.3
-
8
-
-
0038264036
-
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
-
Mora JR, Bono MR, Manjunath N, et al. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 2003; 424:88-93.
-
(2003)
Nature
, vol.424
, pp. 88-93
-
-
Mora, J.R.1
Bono, M.R.2
Manjunath, N.3
-
9
-
-
0141449950
-
Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): Requirement for GALT dendritic cells and adjuvant
-
Johansson-Lindbom B, Svensson M, Wurbel MA, et al. Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant. J Exp Med 2003; 198:963-969.
-
(2003)
J Exp Med
, vol.198
, pp. 963-969
-
-
Johansson-Lindbom, B.1
Svensson, M.2
Wurbel, M.A.3
-
10
-
-
33751223544
-
Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells
-
Mora JR, Iwata M, Eksteen B, et al. Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells. Science 2006; 314:1157-1160.
-
(2006)
Science
, vol.314
, pp. 1157-1160
-
-
Mora, J.R.1
Iwata, M.2
Eksteen, B.3
-
11
-
-
26844538936
-
Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing
-
Johansson-Lindbom B, Svensson M, Pabst O, et al. Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J Exp Med 2005; 202:1063-1073.
-
(2005)
J Exp Med
, vol.202
, pp. 1063-1073
-
-
Johansson-Lindbom, B.1
Svensson, M.2
Pabst, O.3
-
12
-
-
48849115839
-
Differentiation and homing of IgA-secreting cells
-
Mora JR, Von Andrian UH. Differentiation and homing of IgA-secreting cells. Mucosal Immunology 2008; 1:96-109.
-
(2008)
Mucosal Immunology
, vol.1
, pp. 96-109
-
-
Mora, J.R.1
Von Andrian, U.H.2
-
13
-
-
39449098115
-
HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells
-
This paper describes a novel mechanism by which HIV-1 envelope induces signal transduction and upregulation of adhesion molecules in mucosal-homing T cells, potentially enhancing cell-to-cell spread of HIV infection
-
Arthos J, Cicala C, Martinelli E, et al. HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. Nat Immunol 2008; 9:301-309. This paper describes a novel mechanism by which HIV-1 envelope induces signal transduction and upregulation of adhesion molecules in mucosal-homing T cells, potentially enhancing cell-to-cell spread of HIV infection.
-
(2008)
Nat Immunol
, vol.9
, pp. 301-309
-
-
Arthos, J.1
Cicala, C.2
Martinelli, E.3
-
14
-
-
34547788180
-
A functionally specialized population of mucosal CD103+DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
-
Coombes JL, Siddiqui KR, Arancibia-Carcamo CV, et al. A functionally specialized population of mucosal CD103+DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 2007; 204:1757-1764.
-
(2007)
J Exp Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Carcamo, C.V.3
-
15
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
This study identified retinoic acid as a key mediator of the balance between induction of pro-inflammatory (Th17) and tolerogenic (Treg) CD4 T-cell subsets
-
Mucida D, Park Y, Kim G, et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007; 317:256-260. This study identified retinoic acid as a key mediator of the balance between induction of pro-inflammatory (Th17) and tolerogenic (Treg) CD4 T-cell subsets.
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
-
16
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, et al. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006; 24:179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
-
17
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov II, McKenzie BS, Zhou L, et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006; 126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
-
18
-
-
41449110468
-
Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
-
This paper linked a defect in IL-17 production and Th17 differentiation to the pathogenesis of Job's syndrome, a disease characterized by severe, recurrent bacterial infections
-
Milner JD, Brenchley JM, Laurence A, et al. Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 2008; 452:773-776. This paper linked a defect in IL-17 production and Th17 differentiation to the pathogenesis of Job's syndrome, a disease characterized by severe, recurrent bacterial infections.
-
(2008)
Nature
, vol.452
, pp. 773-776
-
-
Milner, J.D.1
Brenchley, J.M.2
Laurence, A.3
-
19
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 2005; 6:1133-1141.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
-
20
-
-
67649883328
-
Primary SIV infection causes rapid loss of the balance between TH17 and T regulatory cell populations in pathogenic infection of nonhuman primates [abstract]
-
Stevenson M, Mellors JW, editors, Abstract 117LB
-
Favre D, Lederer S, Kanwar B, et al. Primary SIV infection causes rapid loss of the balance between TH17 and T regulatory cell populations in pathogenic infection of nonhuman primates [abstract]. In: Stevenson M, Mellors JW, editors. 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston. Alexandria: CROI; 2008. Abstract 117LB.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston. Alexandria: CROI
-
-
Favre, D.1
Lederer, S.2
Kanwar, B.3
-
21
-
-
67649890180
-
Preferential loss of TH17 CD4 cells in the gastrointestinal tract of HIV-infected individuals but not SIV-infected sooty mangabeys [abstract]
-
Stevenson M, Mellors JW, editors, Abstract 115
-
Cervasi B, Brenchley JM, Paiardini M, et al. Preferential loss of TH17 CD4 cells in the gastrointestinal tract of HIV-infected individuals but not SIV-infected sooty mangabeys [abstract]. In: Stevenson M, Mellors JW, editors. 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston. Alexandria: CROI; 2008. Abstract 115.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston. Alexandria: CROI
-
-
Cervasi, B.1
Brenchley, J.M.2
Paiardini, M.3
-
22
-
-
67649887250
-
Preferential loss of TH17 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virusinfected macaques [abstract]
-
Stevenson M, Mellors JW, editors, Abstract 116
-
Cecchinato V, Trindade C, Heraud JM, et al. Preferential loss of TH17 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virusinfected macaques [abstract]. In: Stevenson M, Mellors JW, editors. 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston. Alexandria: CROI; 2008. Abstract 116.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston. Alexandria: CROI
-
-
Cecchinato, V.1
Trindade, C.2
Heraud, J.M.3
-
23
-
-
41849142985
-
-
Raffatellu M, Santos RL, Verhoeven DE, et al. Simian immunodeficiency virusinduced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med 2008; 14:421-428. This study demonstrated that SIV infection results in depletion of Th17 cells in ileal mucosa of rhesus macaques, impairing mucosal barrier function and facilitating S. typhimurium dissemination.
-
Raffatellu M, Santos RL, Verhoeven DE, et al. Simian immunodeficiency virusinduced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med 2008; 14:421-428. This study demonstrated that SIV infection results in depletion of Th17 cells in ileal mucosa of rhesus macaques, impairing mucosal barrier function and facilitating S. typhimurium dissemination.
-
-
-
-
24
-
-
33645924682
-
HIV disease: Fallout from a mucosal catastrophe?
-
Brenchley JM, Price DA, Douek DC. HIV disease: fallout from a mucosal catastrophe? Nat Immunol 2006; 7:235-239.
-
(2006)
Nat Immunol
, vol.7
, pp. 235-239
-
-
Brenchley, J.M.1
Price, D.A.2
Douek, D.C.3
-
25
-
-
33845532053
-
Microbial translocation is a cause of systemic immune activation in chronic HIV infection
-
Brenchley JM, Price DA, Schacker TW, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006; 12:1365-1371.
-
(2006)
Nat Med
, vol.12
, pp. 1365-1371
-
-
Brenchley, J.M.1
Price, D.A.2
Schacker, T.W.3
-
27
-
-
33750320502
-
Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART
-
Epple HJ, Loddenkemper C, Kunkel D, et al. Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 2006; 108:3072-3078.
-
(2006)
Blood
, vol.108
, pp. 3072-3078
-
-
Epple, H.J.1
Loddenkemper, C.2
Kunkel, D.3
-
28
-
-
17444407451
-
The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients
-
Andersson J, Boasso A, Nilsson J, et al. The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. J Immunol 2005; 174:3143-3147.
-
(2005)
J Immunol
, vol.174
, pp. 3143-3147
-
-
Andersson, J.1
Boasso, A.2
Nilsson, J.3
-
29
-
-
33144476838
-
Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection
-
Estes JD, Li Q, Reynolds MR, et al. Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection. J Infect Dis 2006; 193:703-712.
-
(2006)
J Infect Dis
, vol.193
, pp. 703-712
-
-
Estes, J.D.1
Li, Q.2
Reynolds, M.R.3
-
30
-
-
33750310898
-
HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS
-
Nilsson J, Boasso A, Velilla PA, et al. HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood 2006; 108:3808-3817.
-
(2006)
Blood
, vol.108
, pp. 3808-3817
-
-
Nilsson, J.1
Boasso, A.2
Velilla, P.A.3
-
31
-
-
36349005400
-
Severe depletion of CD4+ CD25+ regulatory T cells from the intestinal lamina propria but not peripheral blood or lymph nodes during acute simian immunodeficiency virus infection
-
Chase AJ, Sedaghat AR, German JR, et al. Severe depletion of CD4+ CD25+ regulatory T cells from the intestinal lamina propria but not peripheral blood or lymph nodes during acute simian immunodeficiency virus infection. J Virol 2007; 81:12748-12757.
-
(2007)
J Virol
, vol.81
, pp. 12748-12757
-
-
Chase, A.J.1
Sedaghat, A.R.2
German, J.R.3
-
32
-
-
35448968815
-
Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection
-
This study found a correlation between regulatory T-cell markers and viral load in plasma and tissues of SIV-infected rhesus macaques
-
Boasso A, Vaccari M, Hryniewicz A, et al. Regulatory T-cell markers, indoleamine 2,3-dioxygenase, and virus levels in spleen and gut during progressive simian immunodeficiency virus infection. J Virol 2007; 81:11593-11603. This study found a correlation between regulatory T-cell markers and viral load in plasma and tissues of SIV-infected rhesus macaques.
-
(2007)
J Virol
, vol.81
, pp. 11593-11603
-
-
Boasso, A.1
Vaccari, M.2
Hryniewicz, A.3
-
33
-
-
25844482131
-
Perils at mucosal front lines for HIV and SIV and their hosts
-
Haase AT. Perils at mucosal front lines for HIV and SIV and their hosts. Nat Rev Immunol 2005; 5:783-792.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 783-792
-
-
Haase, A.T.1
-
34
-
-
0032540418
-
Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
-
Veazey R, DeMaria M, Chalifoux L, et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 1998; 280:427-431.
-
(1998)
Science
, vol.280
, pp. 427-431
-
-
Veazey, R.1
DeMaria, M.2
Chalifoux, L.3
-
35
-
-
17844374605
-
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
-
Mattapallil JJ, Douek DC, Hill B, et al. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005; 434:1093-1097.
-
(2005)
Nature
, vol.434
, pp. 1093-1097
-
-
Mattapallil, J.J.1
Douek, D.C.2
Hill, B.3
-
36
-
-
17844376742
-
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells
-
Li Q, Duan L, Estes JD, et al. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells. Nature 2005; 434:1148-1152.
-
(2005)
Nature
, vol.434
, pp. 1148-1152
-
-
Li, Q.1
Duan, L.2
Estes, J.D.3
-
37
-
-
21644488003
-
CD8+ T-lymphocyte response to major immunodominant epitopes after vaginal exposure to simian immunodeficiency virus: Too late and too little
-
Reynolds MR, Rakasz E, Skinner PJ, et al. CD8+ T-lymphocyte response to major immunodominant epitopes after vaginal exposure to simian immunodeficiency virus: too late and too little. J Virol 2005; 79:9228-9235.
-
(2005)
J Virol
, vol.79
, pp. 9228-9235
-
-
Reynolds, M.R.1
Rakasz, E.2
Skinner, P.J.3
-
38
-
-
33644772169
-
Perforin expression in the gastrointestinal mucosa is limited to acute simian immunodeficiency virus infection
-
Quigley MF, Abel K, Zuber B, et al. Perforin expression in the gastrointestinal mucosa is limited to acute simian immunodeficiency virus infection. J Virol 2006; 80:3083-3087.
-
(2006)
J Virol
, vol.80
, pp. 3083-3087
-
-
Quigley, M.F.1
Abel, K.2
Zuber, B.3
-
39
-
-
37349014838
-
Depletion of natural killer cells in the colonic lamina propria of viraemic HIV-1-infected individuals
-
Mela CM, Steel A, Lindsay J, et al. Depletion of natural killer cells in the colonic lamina propria of viraemic HIV-1-infected individuals. AIDS 2007; 21:2177-2182.
-
(2007)
AIDS
, vol.21
, pp. 2177-2182
-
-
Mela, C.M.1
Steel, A.2
Lindsay, J.3
-
40
-
-
0030011639
-
Intraepithelial gamma/delta T cells in duodenal mucosa are related to the immune state and survival time in AIDS
-
Nilssen DE, Muller F, Oktedalen O, et al. Intraepithelial gamma/delta T cells in duodenal mucosa are related to the immune state and survival time in AIDS. J Virol 1996; 70:3545-3550.
-
(1996)
J Virol
, vol.70
, pp. 3545-3550
-
-
Nilssen, D.E.1
Muller, F.2
Oktedalen, O.3
-
41
-
-
0033624681
-
The role of gammadelta T cells in generating antiviral factors and beta-chemokines in protection against mucosal simian immunodeficiency virus infection
-
Lehner T, Mitchell E, Bergmeier L, et al. The role of gammadelta T cells in generating antiviral factors and beta-chemokines in protection against mucosal simian immunodeficiency virus infection. Eur J Immunol 2000; 30:2245-2256.
-
(2000)
Eur J Immunol
, vol.30
, pp. 2245-2256
-
-
Lehner, T.1
Mitchell, E.2
Bergmeier, L.3
-
42
-
-
38349153297
-
Gamma/Delta T-cell functional responses differ after pathogenic human immunodeficiency virus and nonpathogenic simian immunodeficiency virus infections
-
This study is one of the few to address the role of γδT cells in HIV/SIV infection; however, this study focused primarily on peripheral blood
-
Kosub DA, Lehrman G, Milush JM, et al. Gamma/Delta T-cell functional responses differ after pathogenic human immunodeficiency virus and nonpathogenic simian immunodeficiency virus infections. J Virol 2008; 82:1155-1165. This study is one of the few to address the role of γδT cells in HIV/SIV infection; however, this study focused primarily on peripheral blood.
-
(2008)
J Virol
, vol.82
, pp. 1155-1165
-
-
Kosub, D.A.1
Lehrman, G.2
Milush, J.M.3
-
43
-
-
0034791052
-
Emergence and kinetics of simian immunodeficiency virus-specific CD8(+) T cells in the intestines of macaques during primary infection
-
Veazey RS, Gauduin MC, Mansfield KG, et al. Emergence and kinetics of simian immunodeficiency virus-specific CD8(+) T cells in the intestines of macaques during primary infection. J Virol 2001; 75:10515-10519.
-
(2001)
J Virol
, vol.75
, pp. 10515-10519
-
-
Veazey, R.S.1
Gauduin, M.C.2
Mansfield, K.G.3
-
44
-
-
0034630946
-
Characterization of HIV-1-specific cytotoxic T lymphocytes expressing the mucosal lymphocyte integrin CD103 in rectal and duodenal lymphoid tissue of HIV-1-infected subjects
-
Shacklett BL, Beadle TJ, Pacheco PA, et al. Characterization of HIV-1-specific cytotoxic T lymphocytes expressing the mucosal lymphocyte integrin CD103 in rectal and duodenal lymphoid tissue of HIV-1-infected subjects. Virology 2000; 270:317-327.
-
(2000)
Virology
, vol.270
, pp. 317-327
-
-
Shacklett, B.L.1
Beadle, T.J.2
Pacheco, P.A.3
-
45
-
-
0031047593
-
HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women
-
Musey L, Hu Y, Eckert L, et al. HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women. J Exp Med 1997; 185:293-303.
-
(1997)
J Exp Med
, vol.185
, pp. 293-303
-
-
Musey, L.1
Hu, Y.2
Eckert, L.3
-
46
-
-
1842292203
-
Direct ex vivo simian immunodeficiency virus (SIV)-specific cytotoxic activity detected from small intestine intraepithelial lymphocytes of SIV-infected macaques at an advanced stage of infection
-
Couedel-Courteille A, Le Grand R, Tulliez M, et al. Direct ex vivo simian immunodeficiency virus (SIV)-specific cytotoxic activity detected from small intestine intraepithelial lymphocytes of SIV-infected macaques at an advanced stage of infection. J Virol 1997; 71:1052-1057.
-
(1997)
J Virol
, vol.71
, pp. 1052-1057
-
-
Couedel-Courteille, A.1
Le Grand, R.2
Tulliez, M.3
-
47
-
-
0035895053
-
Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys
-
Schmitz JE, Veazey RS, Kuroda MJ, et al. Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys. Blood 2001; 98:3757-3761.
-
(2001)
Blood
, vol.98
, pp. 3757-3761
-
-
Schmitz, J.E.1
Veazey, R.S.2
Kuroda, M.J.3
-
48
-
-
0037213930
-
Ontogeny and specificity of mucosal and blood human immunodeficiency virus-1 specific CD8+ cytotoxic T lymphocytes
-
Musey L, Ding Y, Cao J, et al. Ontogeny and specificity of mucosal and blood human immunodeficiency virus-1 specific CD8+ cytotoxic T lymphocytes. J Virol 2003; 77:291-300.
-
(2003)
J Virol
, vol.77
, pp. 291-300
-
-
Musey, L.1
Ding, Y.2
Cao, J.3
-
49
-
-
20144363311
-
Parallel human immunodeficiency virus type 1-specific CD8+ T-lymphocyte responses in blood and mucosa during chronic infection
-
Ibarrondo FJ, Anton PA, Fuerst M, et al. Parallel human immunodeficiency virus type 1-specific CD8+ T-lymphocyte responses in blood and mucosa during chronic infection. J Virol 2005; 79:4289-4297.
-
(2005)
J Virol
, vol.79
, pp. 4289-4297
-
-
Ibarrondo, F.J.1
Anton, P.A.2
Fuerst, M.3
-
51
-
-
32044442312
-
Cutting edge: Gut microenvironment promotes differentiation of a unique memory CD8 T cell population
-
Masopust D, Vezys V, Wherry EJ, et al. Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. J Immunol 2006; 176:2079-2083.
-
(2006)
J Immunol
, vol.176
, pp. 2079-2083
-
-
Masopust, D.1
Vezys, V.2
Wherry, E.J.3
-
52
-
-
0035162229
-
Intraepithelial lymphocytes: Exploring the Third Way in immunology
-
Hayday A, Theodoridis E, Ramsburg E, Shires J. Intraepithelial lymphocytes: exploring the Third Way in immunology. Nat Immunol 2001; 2:997-1003.
-
(2001)
Nat Immunol
, vol.2
, pp. 997-1003
-
-
Hayday, A.1
Theodoridis, E.2
Ramsburg, E.3
Shires, J.4
-
53
-
-
0038033158
-
Trafficking of HIV-1-specific CD8+ T-cells to gut-associated lymphoid tissue (GALT) during chronic infection
-
Shacklett BL, Cox CA, Sandberg JK, et al. Trafficking of HIV-1-specific CD8+ T-cells to gut-associated lymphoid tissue (GALT) during chronic infection. J Virol 2003; 77:5621-5631.
-
(2003)
J Virol
, vol.77
, pp. 5621-5631
-
-
Shacklett, B.L.1
Cox, C.A.2
Sandberg, J.K.3
-
54
-
-
2942737129
-
Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: Implications for immune control of HIV-1 infection
-
Shacklett BL, Cox CA, Quigley MF, et al. Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection. J Immunol 2004; 173:641-648.
-
(2004)
J Immunol
, vol.173
, pp. 641-648
-
-
Shacklett, B.L.1
Cox, C.A.2
Quigley, M.F.3
-
55
-
-
34249774014
-
Multifunctional HIVgag specific CD8+ T-cell responses in rectal mucosa and PBMC during chronic HIV-1 infection
-
This study found higher magnitude HIVgag-specific CD8+ T-cell responses in rectal mucosa as compared with PBMC of individuals with chronic HIV infection and not on antiretroviral therapy
-
Critchfield JW, Lemongello D, Walker DH, et al. Multifunctional HIVgag specific CD8+ T-cell responses in rectal mucosa and PBMC during chronic HIV-1 infection. J Virol 2007; 81:5460-5471. This study found higher magnitude HIVgag-specific CD8+ T-cell responses in rectal mucosa as compared with PBMC of individuals with chronic HIV infection and not on antiretroviral therapy.
-
(2007)
J Virol
, vol.81
, pp. 5460-5471
-
-
Critchfield, J.W.1
Lemongello, D.2
Walker, D.H.3
-
56
-
-
67649890177
-
Functionality of rectal HIV-1-specific CD8+ T-cells during chronic infection correlates with clinical status [abstract]
-
Barouch DH, Mascola JR, McElrath MJ, editors, Keystone Symposia;, Abstract 352
-
Critchfield JW, Young DH, Hayes TL, et al. Functionality of rectal HIV-1-specific CD8+ T-cells during chronic infection correlates with clinical status [abstract]. In: Barouch DH, Mascola JR, McElrath MJ, editors. Keystone Symposium, HIV Vaccines: Progress and Prospects (X7); 27 March -1 April 2008; Banff. Silverthorne: Keystone Symposia; 2008. Abstract 352.
-
(2008)
Keystone Symposium, HIV Vaccines: Progress and Prospects (X7); 27 March -1 April 2008; Banff. Silverthorne
-
-
Critchfield, J.W.1
Young, D.H.2
Hayes, T.L.3
-
57
-
-
46049120719
-
High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage
-
This study found strong, polyfunctional HIV-specific T-cell responses in bronchoalveolar lavage, but not terminal ileum of HIV-infected subjects
-
Brenchley JM, Knox KS, Asher AI, et al. High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage. Mucosal Immunology 2008; 1:49-58. This study found strong, polyfunctional HIV-specific T-cell responses in bronchoalveolar lavage, but not terminal ileum of HIV-infected subjects.
-
(2008)
Mucosal Immunology
, vol.1
, pp. 49-58
-
-
Brenchley, J.M.1
Knox, K.S.2
Asher, A.I.3
-
58
-
-
67649869605
-
Polyfunctional T-cells in the rectal mucosa of HIV controllers [abstract]
-
Barouch DH, Mascola JR, McElrath MJ, editors, Keystone Symposia;, Abstract 143
-
Ferre AL, Critchfield JW, Hunt PW, et al. Polyfunctional T-cells in the rectal mucosa of HIV controllers [abstract]. In: Barouch DH, Mascola JR, McElrath MJ, editors. Keystone Symposium, HIV Vaccines: Progress and Prospects (X7); 27 March -1 April 2008; Banff. Silverthorne: Keystone Symposia; 2008. Abstract 143.
-
(2008)
Keystone Symposium, HIV Vaccines: Progress and Prospects (X7); 27 March -1 April 2008; Banff. Silverthorne
-
-
Ferre, A.L.1
Critchfield, J.W.2
Hunt, P.W.3
-
59
-
-
0033952103
-
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
-
Baba TW, Liska V, Hofmann-Lehmann R, et al. Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med 2000; 6:200-206.
-
(2000)
Nat Med
, vol.6
, pp. 200-206
-
-
Baba, T.W.1
Liska, V.2
Hofmann-Lehmann, R.3
-
60
-
-
0033951746
-
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
-
Mascola JR, Stiegler G, VanCott TC, et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med 2000; 6:207-210.
-
(2000)
Nat Med
, vol.6
, pp. 207-210
-
-
Mascola, J.R.1
Stiegler, G.2
VanCott, T.C.3
-
61
-
-
33750608831
-
Humoral immune responses to the human immunodeficiency virus type-1 (HIV-1) in the genital tract compared to other mucosal sites
-
Mestecky J. Humoral immune responses to the human immunodeficiency virus type-1 (HIV-1) in the genital tract compared to other mucosal sites. J Reprod Immunol 2006; 72:1-17.
-
(2006)
J Reprod Immunol
, vol.72
, pp. 1-17
-
-
Mestecky, J.1
-
62
-
-
9444249960
-
Women with cervicovaginal antibody-dependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads
-
Nag P, Kim J, Sapiega V, et al. Women with cervicovaginal antibody-dependent cell-mediated cytotoxicity have lower genital HIV-1 RNA loads. J Infect Dis 2004; 190:1970-1978.
-
(2004)
J Infect Dis
, vol.190
, pp. 1970-1978
-
-
Nag, P.1
Kim, J.2
Sapiega, V.3
-
63
-
-
33750076960
-
Saliva can mediate HIV-1-specific antibodydependent cell-mediated cytotoxicity
-
Kim JS, Nag P, Landay AL, et al. Saliva can mediate HIV-1-specific antibodydependent cell-mediated cytotoxicity. FEMS Immunol Med Microbiol 2006; 48:267-273.
-
(2006)
FEMS Immunol Med Microbiol
, vol.48
, pp. 267-273
-
-
Kim, J.S.1
Nag, P.2
Landay, A.L.3
-
64
-
-
36749022726
-
-
Chomont N, Hocini H, Gody JC, et al. Neutralizing monoclonal antibodies to human immunodeficiency virus type 1 do not inhibit viral transcytosis through mucosal epithelial cells. Virology 2008; 370:246-254. This study demonstrated that the best-characterized neutralizing monoclonal antibodies to HIV are unable to block transcytosis through an epithelial monolayer in vitro; however, results also suggested that certain polyclonal or polymeric (i.e., S-IgA) antibodies may block HIV attachment by agglutination of virus particles, a process distinct from classic neutralization.
-
Chomont N, Hocini H, Gody JC, et al. Neutralizing monoclonal antibodies to human immunodeficiency virus type 1 do not inhibit viral transcytosis through mucosal epithelial cells. Virology 2008; 370:246-254. This study demonstrated that the best-characterized neutralizing monoclonal antibodies to HIV are unable to block transcytosis through an epithelial monolayer in vitro; however, results also suggested that certain polyclonal or polymeric (i.e., S-IgA) antibodies may block HIV attachment by agglutination of virus particles, a process distinct from classic neutralization.
-
-
-
-
65
-
-
0032906032
-
Epidemiologic and biologic characterization of a cohort of human immunodeficiency virus type 1 highly exposed, persistently seronegative female sex workers in northern Thailand. Chiang Mai HEPS Working Group
-
Beyrer C, Artenstein AW, Rugpao S, et al. Epidemiologic and biologic characterization of a cohort of human immunodeficiency virus type 1 highly exposed, persistently seronegative female sex workers in northern Thailand. Chiang Mai HEPS Working Group. J Infect Dis 1999; 179:59-67.
-
(1999)
J Infect Dis
, vol.179
, pp. 59-67
-
-
Beyrer, C.1
Artenstein, A.W.2
Rugpao, S.3
-
66
-
-
0032989686
-
HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers
-
Kaul R, Trabattoni D, Bwayo JJ, et al. HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers. AIDS 1999; 13:23-29.
-
(1999)
AIDS
, vol.13
, pp. 23-29
-
-
Kaul, R.1
Trabattoni, D.2
Bwayo, J.J.3
-
67
-
-
0035895644
-
Mucosal IgA in exposed, uninfected subjects: Evidence for a role in protection against HIV infection
-
Kaul R, Plummer F, Clerici M, et al. Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection. AIDS 2001; 15:431-432.
-
(2001)
AIDS
, vol.15
, pp. 431-432
-
-
Kaul, R.1
Plummer, F.2
Clerici, M.3
-
68
-
-
0040272195
-
Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV- seropositive persons
-
Mazzoli S, Lopalco L, Salvi A, et al. Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV- seropositive persons. J Infect Dis 1999; 180:871-875.
-
(1999)
J Infect Dis
, vol.180
, pp. 871-875
-
-
Mazzoli, S.1
Lopalco, L.2
Salvi, A.3
-
69
-
-
0030702772
-
HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals
-
Mazzoli S, Trabattoni D, Lo Caputo S, et al. HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals. Nat Med 1997; 3:1250-1257.
-
(1997)
Nat Med
, vol.3
, pp. 1250-1257
-
-
Mazzoli, S.1
Trabattoni, D.2
Lo Caputo, S.3
-
70
-
-
0034327707
-
Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells
-
Devito C, Broliden K, Kaul R, et al. Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells. J Immunol 2000; 165:5170-5176.
-
(2000)
J Immunol
, vol.165
, pp. 5170-5176
-
-
Devito, C.1
Broliden, K.2
Kaul, R.3
-
71
-
-
0034622980
-
Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate
-
Devito C, Hinkula J, Kaul R, et al. Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate. AIDS 2000; 14:1917-1920.
-
(2000)
AIDS
, vol.14
, pp. 1917-1920
-
-
Devito, C.1
Hinkula, J.2
Kaul, R.3
-
72
-
-
41349105330
-
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers
-
Hirbod T, Kaul R, Reichard C, et al. HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers. AIDS 2008; 22:727-735.
-
(2008)
AIDS
, vol.22
, pp. 727-735
-
-
Hirbod, T.1
Kaul, R.2
Reichard, C.3
-
73
-
-
40449129166
-
HIV-1 neutralizing activity is correlated with increased levels of chemokines in saliva of HIV-1-exposed uninfected individuals
-
Hirbod T, Reichard C, Hasselrot K, et al. HIV-1 neutralizing activity is correlated with increased levels of chemokines in saliva of HIV-1-exposed uninfected individuals. Curr HIV Res 2008; 6:28-33.
-
(2008)
Curr HIV Res
, vol.6
, pp. 28-33
-
-
Hirbod, T.1
Reichard, C.2
Hasselrot, K.3
-
74
-
-
0035576930
-
Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women
-
Belec L, Ghys PD, Hocini H, et al. Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women. J Infect Dis 2001; 184:1412-1422.
-
(2001)
J Infect Dis
, vol.184
, pp. 1412-1422
-
-
Belec, L.1
Ghys, P.D.2
Hocini, H.3
-
75
-
-
33846818809
-
Plasma and mucosal fluid from HIV type 1-infected patients but not from HIV type 1-exposed uninfected subjects prevent HIV type 1-exposed DC from infecting other target cells
-
Soderlund J, Hirbod T, Smed-Sorensen A, et al. Plasma and mucosal fluid from HIV type 1-infected patients but not from HIV type 1-exposed uninfected subjects prevent HIV type 1-exposed DC from infecting other target cells. AIDS Res Hum Retroviruses 2007; 23:101-106.
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 101-106
-
-
Soderlund, J.1
Hirbod, T.2
Smed-Sorensen, A.3
-
76
-
-
0037083092
-
Correlates of nontransmission in United States women at high risk of HIV-1 transmission through sexual exposure
-
Skurnick JH, Palumbo P, De Vico A, et al. Correlates of nontransmission in United States women at high risk of HIV-1 transmission through sexual exposure. J Infect Dis 2002; 185:428-438.
-
(2002)
J Infect Dis
, vol.185
, pp. 428-438
-
-
Skurnick, J.H.1
Palumbo, P.2
De Vico, A.3
-
77
-
-
0033946568
-
Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia
-
Dorrell L, Hessell AJ, Wang M, et al. Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia. AIDS 2000; 14:1117-1122.
-
(2000)
AIDS
, vol.14
, pp. 1117-1122
-
-
Dorrell, L.1
Hessell, A.J.2
Wang, M.3
-
78
-
-
36048991264
-
-
Letvin NL, Rao SS, Dang V, et al. No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys. J Virol 2007; 81:12368-12374. This study presented an animalmodel to elucidate potential correlates of protection in HEPSindividuals.Rhesusmacaques were exposed to repeated low-dose atraumatic rectal challenge with SIVmac. The macaques that remained uninfected did not show evidence of SIV-specific mucosal antibodies or HIV-specific T-cell responses.
-
Letvin NL, Rao SS, Dang V, et al. No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys. J Virol 2007; 81:12368-12374. This study presented an animalmodel to elucidate potential correlates of protection in HEPSindividuals.Rhesusmacaques were exposed to repeated low-dose atraumatic rectal challenge with SIVmac. The macaques that remained uninfected did not show evidence of SIV-specific mucosal antibodies or HIV-specific T-cell responses.
-
-
-
-
79
-
-
0031456989
-
Abnormal predominance of IgG in HIV-specific antibodies produced by short-term cultured duodenal biopsy specimens from HIV-infected patients
-
Schneider T, Zippel T, Schmidt W, et al. Abnormal predominance of IgG in HIV-specific antibodies produced by short-term cultured duodenal biopsy specimens from HIV-infected patients. J Acquir Immune Defic Syndr Hum Retrovirol 1997; 16:333-339.
-
(1997)
J Acquir Immune Defic Syndr Hum Retrovirol
, vol.16
, pp. 333-339
-
-
Schneider, T.1
Zippel, T.2
Schmidt, W.3
-
80
-
-
0032895731
-
Human immunodeficiency virus type 1 and mucosal humoral defense
-
Janoff EN, Scamurra RW, Sanneman TC, et al. Human immunodeficiency virus type 1 and mucosal humoral defense. J Infect Dis 1999; 179 (Suppl 3): S475-S479.
-
(1999)
J Infect Dis
, vol.179
, Issue.SUPPL. 3
-
-
Janoff, E.N.1
Scamurra, R.W.2
Sanneman, T.C.3
-
81
-
-
5644235133
-
Paucity of antigen-specific IgA responses in sera and external secretions of HIV-type 1-infected individuals
-
Mestecky J, Jackson S, Moldoveanu Z, et al. Paucity of antigen-specific IgA responses in sera and external secretions of HIV-type 1-infected individuals. AIDS Res Hum Retroviruses 2004; 20:972-988.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, pp. 972-988
-
-
Mestecky, J.1
Jackson, S.2
Moldoveanu, Z.3
-
82
-
-
0036784646
-
Mucosal plasma cell repertoire during HIV-1 infection
-
Scamurra RW, Nelson DB, Lin XM, et al. Mucosal plasma cell repertoire during HIV-1 infection. J Immunol 2002; 169:4008-4016.
-
(2002)
J Immunol
, vol.169
, pp. 4008-4016
-
-
Scamurra, R.W.1
Nelson, D.B.2
Lin, X.M.3
-
83
-
-
1642393388
-
Intestinal B cell hyperactivity in AIDSis controlled by highly active antiretroviral therapy
-
Nilssen DE, Oktedalen O, Brandtzaeg P. Intestinal B cell hyperactivity in AIDSis controlled by highly active antiretroviral therapy. Gut 2004; 53:487-493.
-
(2004)
Gut
, vol.53
, pp. 487-493
-
-
Nilssen, D.E.1
Oktedalen, O.2
Brandtzaeg, P.3
-
84
-
-
40049100634
-
Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease
-
Moir S, Malaspina A, Ho J, et al. Normalization of B cell counts and subpopulations after antiretroviral therapy in chronic HIV disease. J Infect Dis 2008; 197:572-579.
-
(2008)
J Infect Dis
, vol.197
, pp. 572-579
-
-
Moir, S.1
Malaspina, A.2
Ho, J.3
-
85
-
-
33645288761
-
Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells
-
Qiao X, He B, Chiu A, et al. Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells. Nat Immunol 2006; 7:302-310.
-
(2006)
Nat Immunol
, vol.7
, pp. 302-310
-
-
Qiao, X.1
He, B.2
Chiu, A.3
-
86
-
-
33646045632
-
HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors
-
He B, Qiao X, Klasse PJ, et al. HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors. J Immunol 2006; 176:3931-3941.
-
(2006)
J Immunol
, vol.176
, pp. 3931-3941
-
-
He, B.1
Qiao, X.2
Klasse, P.J.3
-
87
-
-
0035869152
-
Human immunodeficiency virus-specific and CD3-redirected cytotoxic T lymphocyte activity in the human female reproductive tract: Lack of correlation between mucosa and peripheral blood
-
White HD, Musey LK, Andrews MM, et al. Human immunodeficiency virus-specific and CD3-redirected cytotoxic T lymphocyte activity in the human female reproductive tract: lack of correlation between mucosa and peripheral blood. J Infect Dis 2001; 183:977-983.
-
(2001)
J Infect Dis
, vol.183
, pp. 977-983
-
-
White, H.D.1
Musey, L.K.2
Andrews, M.M.3
-
88
-
-
67649883327
-
Mucosal assessment of T cell magnitude and specificity during HIV infection [abstract
-
editors, August, Seattle. Global HIV Vaccine Enterprise;
-
Passmore JA. Mucosal assessment of T cell magnitude and specificity during HIV infection [abstract]. In: Corey L, Esparza J, editors. AIDS Vaccine 2007; 20-23 August 2007; Seattle. Global HIV Vaccine Enterprise; 2007.
-
(2007)
AIDS Vaccine 2007; 20-23
-
-
Passmore, J.A.1
-
89
-
-
0038205356
-
Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIVinfected women
-
Kaul R, Thottingal P, Kimani J, et al. Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIVinfected women. AIDS 2003; 17:1139-1144.
-
(2003)
AIDS
, vol.17
, pp. 1139-1144
-
-
Kaul, R.1
Thottingal, P.2
Kimani, J.3
-
90
-
-
0034622954
-
Quantification of HIV-1-specific T-cell responses at the mucosal cervicovaginal surface
-
Shacklett BL, Cu-Uvin S, Beadle TJ, et al. Quantification of HIV-1-specific T-cell responses at the mucosal cervicovaginal surface. AIDS 2000; 14:1911-1915.
-
(2000)
AIDS
, vol.14
, pp. 1911-1915
-
-
Shacklett, B.L.1
Cu-Uvin, S.2
Beadle, T.J.3
-
91
-
-
0028785243
-
Antiviral cytotoxic T lymphocytes in vaginal mucosa of simian immunodeficiency virus-infected rhesus macaques
-
Lohman BL, Miller CJ, McChesney MB. Antiviral cytotoxic T lymphocytes in vaginal mucosa of simian immunodeficiency virus-infected rhesus macaques. J Immunol 1995; 155:5855-5860.
-
(1995)
J Immunol
, vol.155
, pp. 5855-5860
-
-
Lohman, B.L.1
Miller, C.J.2
McChesney, M.B.3
-
92
-
-
0036133061
-
Cervicovaginal lamina propria lymphocytes: Phenotypic characterization and their importance in cytotoxic T-lymphocyte responses to simian immunodeficiency virus SIVmac251
-
Stevceva L, Kelsall B, Nacsa J, et al. Cervicovaginal lamina propria lymphocytes: phenotypic characterization and their importance in cytotoxic T-lymphocyte responses to simian immunodeficiency virus SIVmac251. J Virol 2002; 76:9-18.
-
(2002)
J Virol
, vol.76
, pp. 9-18
-
-
Stevceva, L.1
Kelsall, B.2
Nacsa, J.3
-
93
-
-
17344381593
-
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1- resistant prostitutes in Nairobi
-
Kaul R, Plummer FA, Kimani J, et al. HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1- resistant prostitutes in Nairobi. J Immunol 2000; 164:1602-1611.
-
(2000)
J Immunol
, vol.164
, pp. 1602-1611
-
-
Kaul, R.1
Plummer, F.A.2
Kimani, J.3
-
94
-
-
0031569259
-
CD3+ CD8+ CTL activity within the human female reproductive tract: Influence of stage of the menstrual cycle and menopause
-
White HD, Crassi KM, Givan AL, et al. CD3+ CD8+ CTL activity within the human female reproductive tract: influence of stage of the menstrual cycle and menopause. J Immunol 1997; 158:3017-3027.
-
(1997)
J Immunol
, vol.158
, pp. 3017-3027
-
-
White, H.D.1
Crassi, K.M.2
Givan, A.L.3
-
95
-
-
0031056227
-
Mucosal immunity in the human female reproductive tract: Cytotoxic T lymphocyte function in the cervix and vagina of premenopausal and postmenopausal women
-
White HD, Yeaman GR, Givan AL, Wira CR. Mucosal immunity in the human female reproductive tract: cytotoxic T lymphocyte function in the cervix and vagina of premenopausal and postmenopausal women. Am J Reprod Immunol 1997; 37:30-38.
-
(1997)
Am J Reprod Immunol
, vol.37
, pp. 30-38
-
-
White, H.D.1
Yeaman, G.R.2
Givan, A.L.3
Wira, C.R.4
-
96
-
-
0032743544
-
Immunoglobulin concentrations and antigenspecific antibody levels in cervicovaginal lavages of rhesus macaques are influenced by the stage of the menstrual cycle
-
Lu FX, Ma Z, Rourke T, et al. Immunoglobulin concentrations and antigenspecific antibody levels in cervicovaginal lavages of rhesus macaques are influenced by the stage of the menstrual cycle. Infect Immun 1999; 67:6321-6328.
-
(1999)
Infect Immun
, vol.67
, pp. 6321-6328
-
-
Lu, F.X.1
Ma, Z.2
Rourke, T.3
-
97
-
-
0030965069
-
Unique CD8+T cell-rich lymphoid aggregates in human uterine endometrium
-
Yeaman GR, Guyre PM, Fanger MW, et al. Unique CD8+T cell-rich lymphoid aggregates in human uterine endometrium. J Leukoc Biol 1997; 61:427-435.
-
(1997)
J Leukoc Biol
, vol.61
, pp. 427-435
-
-
Yeaman, G.R.1
Guyre, P.M.2
Fanger, M.W.3
-
98
-
-
0038466109
-
Oestradiol regulation of antigen presentation by uterine stromal cells: Role of transforming growth factor-beta production by epithelial cells in mediating antigen-presenting cell function
-
Wira CR, Rossoll RM. Oestradiol regulation of antigen presentation by uterine stromal cells: role of transforming growth factor-beta production by epithelial cells in mediating antigen-presenting cell function. Immunology 2003; 109:398-406.
-
(2003)
Immunology
, vol.109
, pp. 398-406
-
-
Wira, C.R.1
Rossoll, R.M.2
-
99
-
-
9144235510
-
Recruitment of uterine NK cells: Induction of CXC chemokine ligands 10 and 11 in human endometrium by estradiol and progesterone
-
Sentman CL, Meadows SK, Wira CR, Eriksson M. Recruitment of uterine NK cells: induction of CXC chemokine ligands 10 and 11 in human endometrium by estradiol and progesterone. J Immunol 2004; 173:6760-6766.
-
(2004)
J Immunol
, vol.173
, pp. 6760-6766
-
-
Sentman, C.L.1
Meadows, S.K.2
Wira, C.R.3
Eriksson, M.4
-
100
-
-
33846213040
-
NK cell function in the human female reproductive tract
-
Sentman CL, Wira CR, Eriksson M. NK cell function in the human female reproductive tract. Am J Reprod Immunol 2007; 57:108-115.
-
(2007)
Am J Reprod Immunol
, vol.57
, pp. 108-115
-
-
Sentman, C.L.1
Wira, C.R.2
Eriksson, M.3
-
101
-
-
33749864595
-
Cyclic changes in the vaginal epithelium of normal rhesus macaques
-
Poonia B, Walter L, Dufour J, et al. Cyclic changes in the vaginal epithelium of normal rhesus macaques. J Endocrinol 2006; 190:829-835.
-
(2006)
J Endocrinol
, vol.190
, pp. 829-835
-
-
Poonia, B.1
Walter, L.2
Dufour, J.3
-
102
-
-
0031959557
-
The mucosal immune system in the human female reproductive tract: Potential insights into the heterosexual transmission of HIV
-
Yeaman GR, White HD, Howell A, et al. The mucosal immune system in the human female reproductive tract: potential insights into the heterosexual transmission of HIV. AIDS Res Hum Retroviruses 1998; 14 (Suppl 1):S57-S62.
-
(1998)
AIDS Res Hum Retroviruses
, vol.14
, Issue.SUPPL. 1
-
-
Yeaman, G.R.1
White, H.D.2
Howell, A.3
-
103
-
-
23344453110
-
Innate and adaptive immunity in female genital tract: Cellular responses and interactions
-
Wira CR, Fahey JV, Sentman CL, et al. Innate and adaptive immunity in female genital tract: cellular responses and interactions. Immunol Rev 2005; 206:306-335.
-
(2005)
Immunol Rev
, vol.206
, pp. 306-335
-
-
Wira, C.R.1
Fahey, J.V.2
Sentman, C.L.3
-
104
-
-
0037423819
-
Recent observations on HIV type-1 infection in the genital tract of men and women
-
Coombs RW, Reichelderfer PS, Landay AL. Recent observations on HIV type-1 infection in the genital tract of men and women. AIDS 2003; 17:455-480.
-
(2003)
AIDS
, vol.17
, pp. 455-480
-
-
Coombs, R.W.1
Reichelderfer, P.S.2
Landay, A.L.3
-
105
-
-
0029115952
-
Secretory leukocyte protease inhibitor: A human saliva protein exhibiting antihuman immunodeficiency virus 1 activity in vitro
-
McNeely TB, Dealy M, Dripps DJ, et al. Secretory leukocyte protease inhibitor: a human saliva protein exhibiting antihuman immunodeficiency virus 1 activity in vitro. J Clin Invest 1995; 96:456-464.
-
(1995)
J Clin Invest
, vol.96
, pp. 456-464
-
-
McNeely, T.B.1
Dealy, M.2
Dripps, D.J.3
-
106
-
-
0036605884
-
Effect of menstrual status on antibacterial activity and secretory leukocyte protease inhibitor production by human uterine epithelial cells in culture
-
Fahey JV, Wira CR. Effect of menstrual status on antibacterial activity and secretory leukocyte protease inhibitor production by human uterine epithelial cells in culture. J Infect Dis 2002; 185:1606-1613.
-
(2002)
J Infect Dis
, vol.185
, pp. 1606-1613
-
-
Fahey, J.V.1
Wira, C.R.2
-
107
-
-
9244260537
-
Secretory leukocyte protease inhibitor binds to annexin II, a cofactor for macrophage HIV-1 infection
-
Ma G, Greenwell-Wild T, Lei K, et al. Secretory leukocyte protease inhibitor binds to annexin II, a cofactor for macrophage HIV-1 infection. J Exp Med 2004; 200:1337-1346.
-
(2004)
J Exp Med
, vol.200
, pp. 1337-1346
-
-
Ma, G.1
Greenwell-Wild, T.2
Lei, K.3
-
108
-
-
3342878515
-
The antiviral activity of the milk protein lactoferrin against the human immunodeficiency virus type 1
-
Berkhout B, Floris R, Recio I, Visser S. The antiviral activity of the milk protein lactoferrin against the human immunodeficiency virus type 1. Biometals 2004; 17:291-294.
-
(2004)
Biometals
, vol.17
, pp. 291-294
-
-
Berkhout, B.1
Floris, R.2
Recio, I.3
Visser, S.4
-
109
-
-
23944431949
-
Elevated T cell counts and RANTES expression in the genital mucosa of HIV-1-resistant Kenyan commercial sex workers
-
Iqbal SM, Ball TB, Kimani J, et al. Elevated T cell counts and RANTES expression in the genital mucosa of HIV-1-resistant Kenyan commercial sex workers. J Infect Dis 2005; 192:728-738.
-
(2005)
J Infect Dis
, vol.192
, pp. 728-738
-
-
Iqbal, S.M.1
Ball, T.B.2
Kimani, J.3
-
110
-
-
33748993122
-
Upregulation of interferon-alpha and RANTES in the cervix of HIV-1-seronegative women with high-risk behavior
-
Hirbod T, Nilsson J, Andersson S, et al. Upregulation of interferon-alpha and RANTES in the cervix of HIV-1-seronegative women with high-risk behavior. J Acquir Immune Defic Syndr 2006; 43:137-143.
-
(2006)
J Acquir Immune Defic Syndr
, vol.43
, pp. 137-143
-
-
Hirbod, T.1
Nilsson, J.2
Andersson, S.3
-
111
-
-
33748109942
-
Innate host defense of human vaginal and cervical mucosae
-
Cole AM. Innate host defense of human vaginal and cervical mucosae. Curr Top Microbiol Immunol 2006; 306:199-230.
-
(2006)
Curr Top Microbiol Immunol
, vol.306
, pp. 199-230
-
-
Cole, A.M.1
-
112
-
-
28244467481
-
Cationic polypeptides are required for anti-HIV-1 activity of human vaginal fluid
-
Venkataraman N, Cole AL, Svoboda P, et al. Cationic polypeptides are required for anti-HIV-1 activity of human vaginal fluid. J Immunol 2005; 175:7560-7567.
-
(2005)
J Immunol
, vol.175
, pp. 7560-7567
-
-
Venkataraman, N.1
Cole, A.L.2
Svoboda, P.3
-
113
-
-
0032531978
-
Detection of HIV-1-specific CTLs in the semen of HIV-infected individuals
-
Quayle AJ, Coston WM, Trocha AK, et al. Detection of HIV-1-specific CTLs in the semen of HIV-infected individuals. J Immunol 1998; 161:4406-4410.
-
(1998)
J Immunol
, vol.161
, pp. 4406-4410
-
-
Quayle, A.J.1
Coston, W.M.2
Trocha, A.K.3
-
114
-
-
32044448072
-
Activation of HIV type 1 specific cytotoxic T lymphocytes from semen by HIV type 1 antigen-presenting dendritic cells and IL-12
-
Huang XL, Fan Z, Gupta P, Rinaldo CR Jr. Activation of HIV type 1 specific cytotoxic T lymphocytes from semen by HIV type 1 antigen-presenting dendritic cells and IL-12. AIDS Res Hum Retroviruses 2006; 22:93-98.
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, pp. 93-98
-
-
Huang, X.L.1
Fan, Z.2
Gupta, P.3
Rinaldo Jr., C.R.4
-
115
-
-
0032860663
-
Cytotoxic T lymphocytes specific for the simian immunodeficiency virus
-
Letvin NL, Schmitz JE, Jordan HL, et al. Cytotoxic T lymphocytes specific for the simian immunodeficiency virus. Immunol Rev 1999; 170:127-134.
-
(1999)
Immunol Rev
, vol.170
, pp. 127-134
-
-
Letvin, N.L.1
Schmitz, J.E.2
Jordan, H.L.3
-
116
-
-
36849093472
-
Semen-derived amyloid fibrils drastically enhance HIV infection
-
This paper described a novel semen-associated factor, termed SEVI, derived from prostatic acid phosphatase. This factor enhances HIV infectivity in vitro by several orders of magnitude
-
Munch J, Rucker E, Standker L, et al. Semen-derived amyloid fibrils drastically enhance HIV infection. Cell 2007; 131:1059-1071. This paper described a novel semen-associated factor, termed "SEVI", derived from prostatic acid phosphatase. This factor enhances HIV infectivity in vitro by several orders of magnitude.
-
(2007)
Cell
, vol.131
, pp. 1059-1071
-
-
Munch, J.1
Rucker, E.2
Standker, L.3
-
117
-
-
36849092921
-
A seminal finding for understanding HIV transmission
-
Roan NR, Greene WC. A seminal finding for understanding HIV transmission. Cell 2007; 131:1044-1046.
-
(2007)
Cell
, vol.131
, pp. 1044-1046
-
-
Roan, N.R.1
Greene, W.C.2
-
118
-
-
33847390394
-
-
Balzarini J, Van Damme L. Microbicide drug candidates to prevent HIV infection. Lancet 2007; 369:787-797. This paper provides a detailed review of potential HIV microbicides, including drugs with highly specific anti-HIV activity.
-
Balzarini J, Van Damme L. Microbicide drug candidates to prevent HIV infection. Lancet 2007; 369:787-797. This paper provides a detailed review of potential HIV microbicides, including drugs with highly specific anti-HIV activity.
-
-
-
-
119
-
-
36349027008
-
-
van de Wijgert JH, Shattock RJ. Vaginal microbicides: moving ahead after an unexpected setback. AIDS 2007; 21:2369-2376. This paper reviews the results of HIV microbicide trials to date, including a discussion of potential explanations for trial results in the direction of harm.
-
van de Wijgert JH, Shattock RJ. Vaginal microbicides: moving ahead after an unexpected setback. AIDS 2007; 21:2369-2376. This paper reviews the results of HIV microbicide trials to date, including a discussion of potential explanations for trial results in the direction of harm.
-
-
-
-
120
-
-
0035882332
-
The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission
-
Fichorova RN, Tucker LD, Anderson DJ. The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission. J Infect Dis 2001; 184:418-428.
-
(2001)
J Infect Dis
, vol.184
, pp. 418-428
-
-
Fichorova, R.N.1
Tucker, L.D.2
Anderson, D.J.3
-
122
-
-
0037190597
-
Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomised controlled trial
-
Van Damme L, Ramjee G, Alary M, et al. Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial. Lancet 2002; 360:971-977.
-
(2002)
Lancet
, vol.360
, pp. 971-977
-
-
Van Damme, L.1
Ramjee, G.2
Alary, M.3
-
123
-
-
34248198301
-
Microbicide trial screeches to a halt
-
Honey K. Microbicide trial screeches to a halt. J Clin Invest 2007; 117:1116.
-
(2007)
J Clin Invest
, vol.117
, pp. 1116
-
-
Honey, K.1
-
124
-
-
2142652102
-
Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: An update
-
Lard-Whiteford SL, Matecka D, O'Rear JJ, et al. Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update. J Acquir Immune Defic Syndr 2004; 36:541-552.
-
(2004)
J Acquir Immune Defic Syndr
, vol.36
, pp. 541-552
-
-
Lard-Whiteford, S.L.1
Matecka, D.2
O'Rear, J.J.3
-
125
-
-
0036100217
-
AIDS models: Microbicides could learn from vaccines
-
Shattock RJ, Doms RW. AIDS models: microbicides could learn from vaccines. Nat Med 2002; 8:425.
-
(2002)
Nat Med
, vol.8
, pp. 425
-
-
Shattock, R.J.1
Doms, R.W.2
-
126
-
-
7244229669
-
Sensitive methods to detect epithelial disruption: Tests for microhemorrhage in cervicovaginal lavages
-
Moench T, Mehrazar K, Cone R, Blumenthal P. Sensitive methods to detect epithelial disruption: tests for microhemorrhage in cervicovaginal lavages. J Acquir Immune Defic Syndr 2004; 37 (Suppl 3):S194-S200.
-
(2004)
J Acquir Immune Defic Syndr
, vol.37
, Issue.SUPPL. 3
-
-
Moench, T.1
Mehrazar, K.2
Cone, R.3
Blumenthal, P.4
-
127
-
-
27744571425
-
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion
-
Veazey RS, Klasse PJ, Schader SM, et al. Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion. Nature 2005; 438:99-102.
-
(2005)
Nature
, vol.438
, pp. 99-102
-
-
Veazey, R.S.1
Klasse, P.J.2
Schader, S.M.3
-
128
-
-
0345471066
-
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
-
Veazey RS, Shattock RJ, Pope M, et al. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat Med 2003; 9:343-346.
-
(2003)
Nat Med
, vol.9
, pp. 343-346
-
-
Veazey, R.S.1
Shattock, R.J.2
Pope, M.3
-
129
-
-
43249120445
-
-
Shattock RJ, Haynes BF, Pulendran B, et al. Improving Defences at the Portal of HIV Entry: Mucosal and Innate Immunity. PLoS Med 2008; 5:e81. This article summarized a workshop held in June, 2007 in Durham, North Carolina, USA with the goal of identifying key scientific priorities for future studies of innate and mucosal immunity in the context of HIV infection.
-
Shattock RJ, Haynes BF, Pulendran B, et al. Improving Defences at the Portal of HIV Entry: Mucosal and Innate Immunity. PLoS Med 2008; 5:e81. This article summarized a workshop held in June, 2007 in Durham, North Carolina, USA with the goal of identifying key scientific priorities for future studies of innate and mucosal immunity in the context of HIV infection.
-
-
-
|