Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 6, 2011, Pages 2420-2425

  Dietze, Kirsten K ^a   Zelinskyy, Gennadiy ^a   Gibbert, Kathrin ^a   Schimmer, Simone ^a   Francois, Sandra ^a   Myers, Lara ^b   Sparwasser, Tim ^c   Hasenkrug, Kim J ^b   Dittmer, Ulf ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

Author keywords

Cytotoxic T cells; Friend virus; Retrovirus

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL ACTIVITY; CHRONIC DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; FEMALE; IMMUNOTHERAPY; LYMPHOCYTE DEPLETION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RETROVIRUS; RETROVIRUS INFECTION; TRANSGENIC MOUSE; VIRUS LOAD;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; CYTOKINES; LYMPHOCYTE DEPLETION; MICE; MICE, TRANSGENIC; RETROVIRIDAE INFECTIONS; T-LYMPHOCYTES, REGULATORY;

FRIEND MURINE LEUKEMIA VIRUS; HEPATITIS C VIRUS; MUS MUSCULUS;

EID: 79952294178     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1015148108     Document Type: Article

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