-
1
-
-
0034677653
-
A novel family of mammalian taste receptors
-
Adler E., Hoon M.A., Mueller K.L., Chandrashekar J., Ryba N.J., Zuker C.S. A novel family of mammalian taste receptors. Cell 2000, 100:693-702.
-
(2000)
Cell
, vol.100
, pp. 693-702
-
-
Adler, E.1
Hoon, M.A.2
Mueller, K.L.3
Chandrashekar, J.4
Ryba, N.J.5
Zuker, C.S.6
-
2
-
-
0028428521
-
Solid-phase synthesis and structure-activity relationships of analogs of the sweet protein monellin
-
Ariyoshi Y., Kohmura M. Solid-phase synthesis and structure-activity relationships of analogs of the sweet protein monellin. J. Soc. Synth. Org. Chem. Jpn. 1994, 52:359-369.
-
(1994)
J. Soc. Synth. Org. Chem. Jpn.
, vol.52
, pp. 359-369
-
-
Ariyoshi, Y.1
Kohmura, M.2
-
3
-
-
77951901176
-
Key amino acid residues involved in multi-point binding interactions between brazzein a sweet protein and the T1R2-T1R3 human sweet receptor
-
Assadi-Porter F.M., Maillet E.L., Radek J.T., Quijada J., Markley J.L., Max M. Key amino acid residues involved in multi-point binding interactions between brazzein a sweet protein and the T1R2-T1R3 human sweet receptor. J. Mol. Biol. 2010, 398:584-599.
-
(2010)
J. Mol. Biol.
, vol.398
, pp. 584-599
-
-
Assadi-Porter, F.M.1
Maillet, E.L.2
Radek, J.T.3
Quijada, J.4
Markley, J.L.5
Max, M.6
-
4
-
-
0028174033
-
Fingerprinting G-protein-coupled receptors
-
Attwood T.K., Findlay J.B. Fingerprinting G-protein-coupled receptors. Protein Eng. 1994, 7:195-203.
-
(1994)
Protein Eng.
, vol.7
, pp. 195-203
-
-
Attwood, T.K.1
Findlay, J.B.2
-
5
-
-
0031202625
-
Sucrose consumption in mice, major influence of two genetic loci affecting peripheral sensory responses
-
Bachmanov A., Reed D.R., Ninomiya Y., Inoue M., Tordoff M.G., Price R.A., et al. Sucrose consumption in mice, major influence of two genetic loci affecting peripheral sensory responses. Mamm. Genome 1997, 8:545-548.
-
(1997)
Mamm. Genome
, vol.8
, pp. 545-548
-
-
Bachmanov, A.1
Reed, D.R.2
Ninomiya, Y.3
Inoue, M.4
Tordoff, M.G.5
Price, R.A.6
-
6
-
-
0034802060
-
Positional cloning of the mouse saccharin preference (Sac) locus
-
Bachmanov A.A., Li X., Reed D.R., Ohmen J.D., Li S., Chen Z., et al. Positional cloning of the mouse saccharin preference (Sac) locus. Chem. Senses 2001, 26:925-933.
-
(2001)
Chem. Senses
, vol.26
, pp. 925-933
-
-
Bachmanov, A.A.1
Li, X.2
Reed, D.R.3
Ohmen, J.D.4
Li, S.5
Chen, Z.6
-
7
-
-
0037179658
-
A general pseudoreceptor model for sweet compounds, a semi-quantitative prediction of binding affinity for sweet tasting molecules
-
Bassoli A., Drew M.G.B., Merlini L., Morini G. A general pseudoreceptor model for sweet compounds, a semi-quantitative prediction of binding affinity for sweet tasting molecules. J. Med. Chem. 2002, 45:4402-4409.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 4402-4409
-
-
Bassoli, A.1
Drew, M.G.B.2
Merlini, L.3
Morini, G.4
-
8
-
-
0036664904
-
Isovanillyl sweeteners. From molecules to receptors
-
Bassoli A., Merlini L., Morini G. Isovanillyl sweeteners. From molecules to receptors. Pure Appl. Chem. 2002, 74:1181-1187.
-
(2002)
Pure Appl. Chem.
, vol.74
, pp. 1181-1187
-
-
Bassoli, A.1
Merlini, L.2
Morini, G.3
-
9
-
-
33746639193
-
Bitter taste receptors and human bitter taste perception
-
Behrens M., Meyerhof W. Bitter taste receptors and human bitter taste perception. Cell. Mol. Life Sci. 2006, 63:1501-1509.
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, pp. 1501-1509
-
-
Behrens, M.1
Meyerhof, W.2
-
10
-
-
0015185918
-
The nature of taste receptor sites
-
Academic Press, New York, NY, W.D. Neff (Ed.)
-
Beidler L.M., Gross G.W. The nature of taste receptor sites. Contributions to Sensory Physiology 1971, vol. 5:97-127. Academic Press, New York, NY. W.D. Neff (Ed.).
-
(1971)
Contributions to Sensory Physiology
, vol.5
, pp. 97-127
-
-
Beidler, L.M.1
Gross, G.W.2
-
11
-
-
0017225946
-
Evidence for the proximity of sweet and bitter receptor sites
-
Birch G.G., Mylvaganam A.R. Evidence for the proximity of sweet and bitter receptor sites. Nature 1976, 260:632-634.
-
(1976)
Nature
, vol.260
, pp. 632-634
-
-
Birch, G.G.1
Mylvaganam, A.R.2
-
12
-
-
0035937260
-
Pairwise sequence alignment below the twilight zone
-
Blake J.D., Cohen F.E. Pairwise sequence alignment below the twilight zone. J. Mol. Biol. 2001, 307:721-735.
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 721-735
-
-
Blake, J.D.1
Cohen, F.E.2
-
13
-
-
0032766605
-
Quantitative trait loci associated with short-term intake of sucrose saccharin and quinine solutions in laboratory mice
-
Blizard D., Kotlus B., Frank M. Quantitative trait loci associated with short-term intake of sucrose saccharin and quinine solutions in laboratory mice. Chem. Senses 1999, 24:373-385.
-
(1999)
Chem. Senses
, vol.24
, pp. 373-385
-
-
Blizard, D.1
Kotlus, B.2
Frank, M.3
-
14
-
-
0017232757
-
The structure of monellin and its relation to the sweetness of the protein
-
Bohak Z., Li S.L. The structure of monellin and its relation to the sweetness of the protein. Biochim. Biophys. Acta 1976, 427:153-170.
-
(1976)
Biochim. Biophys. Acta
, vol.427
, pp. 153-170
-
-
Bohak, Z.1
Li, S.L.2
-
15
-
-
24944588609
-
The sweet principle of the leaves of Khaa-he-e (Stevia Rebaudiana Bertoni)
-
Bridel M., Lavieille R. The sweet principle of the leaves of Khaa-he-e (Stevia Rebaudiana Bertoni). C. R. Acad. Sci. 1931, 192:1123-1125.
-
(1931)
C. R. Acad. Sci.
, vol.192
, pp. 1123-1125
-
-
Bridel, M.1
Lavieille, R.2
-
16
-
-
0031750166
-
Solution structure of the thermostable sweet-tasting protein brazzein
-
Caldwell J.E., Abildgaard F., Dzakula Z., Ming D., Hellekant G., Markley J.L. Solution structure of the thermostable sweet-tasting protein brazzein. Nat. Struct. Biol. 1998, 5:427-431.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 427-431
-
-
Caldwell, J.E.1
Abildgaard, F.2
Dzakula, Z.3
Ming, D.4
Hellekant, G.5
Markley, J.L.6
-
17
-
-
0029044393
-
The genetic basis of preference for sweet substances among inbred strains of mice preference ratio phenotypes and the alleles of the sac and dpa loci
-
Capeless C., Whitney G. The genetic basis of preference for sweet substances among inbred strains of mice preference ratio phenotypes and the alleles of the sac and dpa loci. Chem. Senses 1995, 20:291-298.
-
(1995)
Chem. Senses
, vol.20
, pp. 291-298
-
-
Capeless, C.1
Whitney, G.2
-
18
-
-
0025138532
-
Conformation activity relationship of sweet molecules. Comparison of aspartame and naphtimidazole-sulfonic acids
-
Castiglione-Morelli M.A., Lelj F., Naider F., Tallon M., Tancredi T., Temussi P.A. Conformation activity relationship of sweet molecules. Comparison of aspartame and naphtimidazole-sulfonic acids. J. Med. Chem. 1990, 33:514-520.
-
(1990)
J. Med. Chem.
, vol.33
, pp. 514-520
-
-
Castiglione-Morelli, M.A.1
Lelj, F.2
Naider, F.3
Tallon, M.4
Tancredi, T.5
Temussi, P.A.6
-
19
-
-
33751084573
-
The receptors and cells for mammalian taste
-
Chandrashekar J., Hoon M.A., Ryba N.J., Zuker C.S. The receptors and cells for mammalian taste. Nature 2006, 444:288-294.
-
(2006)
Nature
, vol.444
, pp. 288-294
-
-
Chandrashekar, J.1
Hoon, M.A.2
Ryba, N.J.3
Zuker, C.S.4
-
20
-
-
0034677655
-
T2Rs function as bitter taste receptors
-
Chandrashekar J., Mueller K.L., Hoon M.A., Adler E., Feng L., Guo W., et al. T2Rs function as bitter taste receptors. Cell 2000, 100:703-711.
-
(2000)
Cell
, vol.100
, pp. 703-711
-
-
Chandrashekar, J.1
Mueller, K.L.2
Hoon, M.A.3
Adler, E.4
Feng, L.5
Guo, W.6
-
21
-
-
0033993988
-
A metabotropic glutamate receptor variant functions as a taste receptor
-
Chaudhari N., Landin A.M., Roper S.D. A metabotropic glutamate receptor variant functions as a taste receptor. Nat. Neurosci. 2000, 3:113-119.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 113-119
-
-
Chaudhari, N.1
Landin, A.M.2
Roper, S.D.3
-
23
-
-
33751505567
-
The heterodimeric sweet taste receptor has multiple potential ligand binding sites
-
Cui M., Jiang P., Maillet E., Max M., Margolskee R.F., Osman R. The heterodimeric sweet taste receptor has multiple potential ligand binding sites. Curr. Pharm. Des. 2006, 12:4591-4600.
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 4591-4600
-
-
Cui, M.1
Jiang, P.2
Maillet, E.3
Max, M.4
Margolskee, R.F.5
Osman, R.6
-
24
-
-
33646130169
-
MD calculations of MNEI a sweet protein: hot spots from hydration sites are consistent with key mutations and receptor interaction derived from docking calculations
-
De Simone A., Spadaccini R., Temussi P.A., Fraternali F. MD calculations of MNEI a sweet protein: hot spots from hydration sites are consistent with key mutations and receptor interaction derived from docking calculations. Biophys. J. 2006, 90:3052-3061.
-
(2006)
Biophys. J.
, vol.90
, pp. 3052-3061
-
-
De Simone, A.1
Spadaccini, R.2
Temussi, P.A.3
Fraternali, F.4
-
25
-
-
0342879408
-
Three-dimensional structure of thaumatin I, an intensely sweet protein
-
de Vos A.M., Hatada M., van der Wel H., Krabbendam H., Peerdeman A.F., Kim S.H. Three-dimensional structure of thaumatin I, an intensely sweet protein. Proc. Natl. Acad. Sci. USA 1985, 82:1406-1409.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 1406-1409
-
-
de Vos, A.M.1
Hatada, M.2
van der Wel, H.3
Krabbendam, H.4
Peerdeman, A.F.5
Kim, S.H.6
-
27
-
-
0019422535
-
Dihydrochalcone sweeteners. A study of the atypical temporal phenomena
-
DuBois G.E., Crosby G.A., Stephenson R.A. Dihydrochalcone sweeteners. A study of the atypical temporal phenomena. J. Med. Chem. 1981, 24:408-428.
-
(1981)
J. Med. Chem.
, vol.24
, pp. 408-428
-
-
DuBois, G.E.1
Crosby, G.A.2
Stephenson, R.A.3
-
28
-
-
33745253400
-
The importance of electrostatic potential in the interaction of sweet proteins with the sweet taste receptor
-
Esposito V., Gallucci R., Picone D., Tancredi T., Temussi P.A. The importance of electrostatic potential in the interaction of sweet proteins with the sweet taste receptor. J. Mol. Biol. 2006, 360:448-456.
-
(2006)
J. Mol. Biol.
, vol.360
, pp. 448-456
-
-
Esposito, V.1
Gallucci, R.2
Picone, D.3
Tancredi, T.4
Temussi, P.A.5
-
29
-
-
0034611739
-
Neurobiology, the good taste of genomics
-
Firestein S. Neurobiology, the good taste of genomics. Nature 2000, 404:552-553.
-
(2000)
Nature
, vol.404
, pp. 552-553
-
-
Firestein, S.1
-
30
-
-
33749240615
-
Modeling the human PTC bitter-taste receptor interactions with bitter tastants
-
Floriano W.B., Hall S., Vaidehi N., Kim U., Drayna D., Goddard W.A. Modeling the human PTC bitter-taste receptor interactions with bitter tastants. J. Mol. Model. 2006, 12:931-941.
-
(2006)
J. Mol. Model.
, vol.12
, pp. 931-941
-
-
Floriano, W.B.1
Hall, S.2
Vaidehi, N.3
Kim, U.4
Drayna, D.5
Goddard, W.A.6
-
31
-
-
0016167786
-
Single-locus control of saccharin preference in mice
-
Fuller J. Single-locus control of saccharin preference in mice. J. Hered. 1974, 65:33-36.
-
(1974)
J. Hered.
, vol.65
, pp. 33-36
-
-
Fuller, J.1
-
32
-
-
0030248921
-
Sweet and taste-modifying proteins, a review
-
Gibbs B.F., Alli I., Mulligan C. Sweet and taste-modifying proteins, a review. Nutr. Res. 1996, 16:1619-1630.
-
(1996)
Nutr. Res.
, vol.16
, pp. 1619-1630
-
-
Gibbs, B.F.1
Alli, I.2
Mulligan, C.3
-
34
-
-
22744438980
-
Cocrystal structures of NC68 Fab identify key interactions for high potency sweetener recognition, implications for the design of synthetic sweeteners
-
Gokulan K., Khare S., Ronning D.R., Linthicum S.D., Sacchettini J.C., Rupp B. Cocrystal structures of NC68 Fab identify key interactions for high potency sweetener recognition, implications for the design of synthetic sweeteners. Biochemistry 2005, 44:9889-9898.
-
(2005)
Biochemistry
, vol.44
, pp. 9889-9898
-
-
Gokulan, K.1
Khare, S.2
Ronning, D.R.3
Linthicum, S.D.4
Sacchettini, J.C.5
Rupp, B.6
-
35
-
-
0031134714
-
Conformational analysis of the dipeptide taste ligand L-aspartyl-D-2-aminobutyric acid-(S)-alpha-ethylbenzylamide and its analogues by NMR spectroscopy, computer simulations and X-ray diffraction studies
-
Goodman M., Zhu Q., Kent D.R., Amino Y., Iacovino R., Benedetti E., et al. Conformational analysis of the dipeptide taste ligand L-aspartyl-D-2-aminobutyric acid-(S)-alpha-ethylbenzylamide and its analogues by NMR spectroscopy, computer simulations and X-ray diffraction studies. J. Pept. Sci. 1997, 3:231-241.
-
(1997)
J. Pept. Sci.
, vol.3
, pp. 231-241
-
-
Goodman, M.1
Zhu, Q.2
Kent, D.R.3
Amino, Y.4
Iacovino, R.5
Benedetti, E.6
-
36
-
-
0016437110
-
PTC taste blindness and the taste of caffeine
-
Hall M.J., Bartoshuk L.M., Cain W.S., Stevens J.C. PTC taste blindness and the taste of caffeine. Nature 1975, 253:442-443.
-
(1975)
Nature
, vol.253
, pp. 442-443
-
-
Hall, M.J.1
Bartoshuk, L.M.2
Cain, W.S.3
Stevens, J.C.4
-
37
-
-
0021971156
-
Crystal structure of aspartame, a peptide sweetener
-
Hatada M., Jancarik J., Graves B., Kim S.-H. Crystal structure of aspartame, a peptide sweetener. J. Am. Chem. Soc. 1985, 107:4279-4282.
-
(1985)
J. Am. Chem. Soc.
, vol.107
, pp. 4279-4282
-
-
Hatada, M.1
Jancarik, J.2
Graves, B.3
Kim, S.-H.4
-
38
-
-
0028871926
-
Dali, a network tool for protein structure comparison
-
Holm L., Sander C. Dali, a network tool for protein structure comparison. Trends Biochem. Sci. 1995, 20:478-480.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 478-480
-
-
Holm, L.1
Sander, C.2
-
39
-
-
0012470990
-
Studies on mabinlin, a sweet protein from the seeds of Capparis masaikai levl. I. Extraction, purification and certain characteristics
-
Hu Z., Min H. Studies on mabinlin, a sweet protein from the seeds of Capparis masaikai levl. I. Extraction, purification and certain characteristics. Acta Bot. Yunnan. 1983, 5:207-212.
-
(1983)
Acta Bot. Yunnan.
, vol.5
, pp. 207-212
-
-
Hu, Z.1
Min, H.2
-
40
-
-
33747860824
-
The cells and logic for mammalian sour taste detection
-
Huang A.L., Chen X., Hoon M.A., Chandrashekar J., Guo W., Traenkner D., et al. The cells and logic for mammalian sour taste detection. Nature 2006, 442:934-938.
-
(2006)
Nature
, vol.442
, pp. 934-938
-
-
Huang, A.L.1
Chen, X.2
Hoon, M.A.3
Chandrashekar, J.4
Guo, W.5
Traenkner, D.6
-
41
-
-
0033534374
-
Structural differences in d and l-monellin in the crystals of racemic mixture
-
Hung L.W., Kohmura M., Ariyoshi Y., Kim S.H. Structural differences in d and l-monellin in the crystals of racemic mixture. J. Mol. Biol. 1999, 285:311-321.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 311-321
-
-
Hung, L.W.1
Kohmura, M.2
Ariyoshi, Y.3
Kim, S.H.4
-
42
-
-
0036856418
-
New seasonings
-
Ikeda K. New seasonings. Chem. Senses 2002, 27:847-849.
-
(2002)
Chem. Senses
, vol.27
, pp. 847-849
-
-
Ikeda, K.1
-
43
-
-
0000599679
-
Tropical plants with unusual taste properties
-
Inglett G.E., May J.F. Tropical plants with unusual taste properties. Econ. Bot. 1968, 22:326-331.
-
(1968)
Econ. Bot.
, vol.22
, pp. 326-331
-
-
Inglett, G.E.1
May, J.F.2
-
44
-
-
84989997494
-
Serendipity berries source of a new intense sweetener
-
Inglett G.E., May J.F. Serendipity berries source of a new intense sweetener. J. Food Sci. 1969, 34:408-411.
-
(1969)
J. Food Sci.
, vol.34
, pp. 408-411
-
-
Inglett, G.E.1
May, J.F.2
-
45
-
-
0018779842
-
The complete amino-acid sequence of the sweet protein thaumatin I
-
Iyengar R.B., Smits P., van der Ouderaa F., van der Wel H., van Brouwershaven J., Ravestein P., et al. The complete amino-acid sequence of the sweet protein thaumatin I. Eur. J. Biochem. 1979, 96:193-204.
-
(1979)
Eur. J. Biochem.
, vol.96
, pp. 193-204
-
-
Iyengar, R.B.1
Smits, P.2
van der Ouderaa, F.3
van der Wel, H.4
van Brouwershaven, J.5
Ravestein, P.6
-
46
-
-
7244238124
-
The cysteine-rich region of T1R3 determines responses to intensely sweet proteins
-
Jiang P., Ji Q., Liu Z., Snyder L.A., Benard L.M., Margolskee R.F., et al. The cysteine-rich region of T1R3 determines responses to intensely sweet proteins. J. Biol. Chem. 2004, 279:45068-45075.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45068-45075
-
-
Jiang, P.1
Ji, Q.2
Liu, Z.3
Snyder, L.A.4
Benard, L.M.5
Margolskee, R.F.6
-
47
-
-
0027050055
-
SAR of sweet molecules, conformational analysis of two hypersweet and two conformationally restricted aspartame analogues
-
Kamphuis J., Lelj F., Tancredi T., Toniolo C., Temussi P.A. SAR of sweet molecules, conformational analysis of two hypersweet and two conformationally restricted aspartame analogues. QSAR 1992, 11:486-491.
-
(1992)
QSAR
, vol.11
, pp. 486-491
-
-
Kamphuis, J.1
Lelj, F.2
Tancredi, T.3
Toniolo, C.4
Temussi, P.A.5
-
48
-
-
0035116853
-
Structure-sweetness relationship in thaumatin, importance of lysine residues
-
Kaneko R., Kitabatake N. Structure-sweetness relationship in thaumatin, importance of lysine residues. Chem. Senses 2001, 26:167-177.
-
(2001)
Chem. Senses
, vol.26
, pp. 167-177
-
-
Kaneko, R.1
Kitabatake, N.2
-
49
-
-
0024338385
-
Redesigning a sweet protein, increased stability and renaturability
-
Kim S.H., Kang C.-H., Kim R., Cho J.M., Lee Y.-B., Lee T.-K. Redesigning a sweet protein, increased stability and renaturability. Protein Eng. 1989, 2:571-575.
-
(1989)
Protein Eng.
, vol.2
, pp. 571-575
-
-
Kim, S.H.1
Kang, C.-H.2
Kim, R.3
Cho, J.M.4
Lee, Y.-B.5
Lee, T.-K.6
-
50
-
-
0002284446
-
Sweet proteins, biochemical studies and genetic engineering
-
ACS Symposium Series, ACS, Washington, DC, D.E. Walters, F.T. Orthofer, G.E. DuBois (Eds.)
-
Kim S.H., Kang C.-H., Cho J.M. Sweet proteins, biochemical studies and genetic engineering. Sweeteners, Discovery, Molecular Design and Chemoreception 1991, vol. 450:28-40. ACS Symposium Series, ACS, Washington, DC. D.E. Walters, F.T. Orthofer, G.E. DuBois (Eds.).
-
(1991)
Sweeteners, Discovery, Molecular Design and Chemoreception
, vol.450
, pp. 28-40
-
-
Kim, S.H.1
Kang, C.-H.2
Cho, J.M.3
-
51
-
-
0033680582
-
A plethora of taste receptors
-
Kinnamon S.C. A plethora of taste receptors. Neuron 2000, 25:507-510.
-
(2000)
Neuron
, vol.25
, pp. 507-510
-
-
Kinnamon, S.C.1
-
52
-
-
0034789987
-
Molecular genetic identification of a candidate receptor gene for sweet taste
-
Kitagawa M., Kusakabe Y., Miura H., Ninomiya Y., Hino A. Molecular genetic identification of a candidate receptor gene for sweet taste. Biochem. Biophys. Res. Commun. 2001, 283:236-242.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.283
, pp. 236-242
-
-
Kitagawa, M.1
Kusakabe, Y.2
Miura, H.3
Ninomiya, Y.4
Hino, A.5
-
53
-
-
0027022363
-
Highly probable active site of the sweet protein monellin
-
Kohmura M., Nio N., Ariyoshi Y. Highly probable active site of the sweet protein monellin. Biosci. Biotechnol. Biochem. 1992, 56:1937-1942.
-
(1992)
Biosci. Biotechnol. Biochem.
, vol.56
, pp. 1937-1942
-
-
Kohmura, M.1
Nio, N.2
Ariyoshi, Y.3
-
54
-
-
0029881007
-
MOLMOL, a program for display and analysis of macromolecular structure
-
Koradi R., Billeter M., Wuethrich K. MOLMOL, a program for display and analysis of macromolecular structure. J. Mol. Graph. 1996, 14:51-55.
-
(1996)
J. Mol. Graph.
, vol.14
, pp. 51-55
-
-
Koradi, R.1
Billeter, M.2
Wuethrich, K.3
-
55
-
-
0034718925
-
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor
-
Kunishima N., Shimada Y., Tsuji Y., Sato T., Yamamoto M., Kumasaka T., et al. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor. Nature 2000, 407:971-977.
-
(2000)
Nature
, vol.407
, pp. 971-977
-
-
Kunishima, N.1
Shimada, Y.2
Tsuji, Y.3
Sato, T.4
Yamamoto, M.5
Kumasaka, T.6
-
56
-
-
0014424842
-
Taste-modifying protein from miracle fruit
-
Kurihara K., Beidler L.M. Taste-modifying protein from miracle fruit. Science 1969, 161:1241-1243.
-
(1969)
Science
, vol.161
, pp. 1241-1243
-
-
Kurihara, K.1
Beidler, L.M.2
-
57
-
-
0034063598
-
Physiological studies on umami taste
-
Kurihara K., Kashiwayanagi M. Physiological studies on umami taste. J. Nutr. 2000, 130:931S-934S.
-
(2000)
J. Nutr.
, vol.130
-
-
Kurihara, K.1
Kashiwayanagi, M.2
-
58
-
-
0033596696
-
Solution structure of a sweet protein single-chain monellin determined by nuclear magnetic resonance and dynamical simulated annealing calculations
-
Lee S.Y., Lee J.H., Chang H.J., Cho J.M., Jung J.W., Lee W. Solution structure of a sweet protein single-chain monellin determined by nuclear magnetic resonance and dynamical simulated annealing calculations. Biochemistry 1999, 38:2340-2346.
-
(1999)
Biochemistry
, vol.38
, pp. 2340-2346
-
-
Lee, S.Y.1
Lee, J.H.2
Chang, H.J.3
Cho, J.M.4
Jung, J.W.5
Lee, W.6
-
59
-
-
0017106241
-
Interaction of alpha-l-aspartyl-l-phenylalanine methyl ester with the receptor site of the sweet taste bud
-
Lelj F., Tancredi T., Temussi P.A., Toniolo C. Interaction of alpha-l-aspartyl-l-phenylalanine methyl ester with the receptor site of the sweet taste bud. J. Am. Chem. Soc. 1976, 98:6669-6675.
-
(1976)
J. Am. Chem. Soc.
, vol.98
, pp. 6669-6675
-
-
Lelj, F.1
Tancredi, T.2
Temussi, P.A.3
Toniolo, C.4
-
60
-
-
0019332167
-
How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins
-
Lesk A.M., Chothia C. How different amino acid sequences determine similar protein structures: the structure and evolutionary dynamics of the globins. J. Mol. Biol. 1980, 136:225-270.
-
(1980)
J. Mol. Biol.
, vol.136
, pp. 225-270
-
-
Lesk, A.M.1
Chothia, C.2
-
61
-
-
0035145485
-
High-resolution genetic mapping of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4
-
Li X., Inoue M., Reed D.R., Hunque T., Puchalski R.B., Tordoff M.G., et al. High-resolution genetic mapping of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4. Mamm. Genome 2001, 12:13-16.
-
(2001)
Mamm. Genome
, vol.12
, pp. 13-16
-
-
Li, X.1
Inoue, M.2
Reed, D.R.3
Hunque, T.4
Puchalski, R.B.5
Tordoff, M.G.6
-
62
-
-
0037007027
-
Human receptors for sweet and umami taste
-
Li X., Staszewski L., Xu H., Durick K., Zoller M., Adler E. Human receptors for sweet and umami taste. Proc. Natl. Acad. Sci. USA 2002, 99:4692-4696.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4692-4696
-
-
Li, X.1
Staszewski, L.2
Xu, H.3
Durick, K.4
Zoller, M.5
Adler, E.6
-
63
-
-
41649105855
-
Crystal structure of Mabinlin II: a novel structural type of sweet proteins and the main structural basis for its sweetness
-
Li D.F., Jiang P., Zhu D.Y., Hu Y., Max M., Wang D.C. Crystal structure of Mabinlin II: a novel structural type of sweet proteins and the main structural basis for its sweetness. J. Struct. Biol. 2008, 162:50-62.
-
(2008)
J. Struct. Biol.
, vol.162
, pp. 50-62
-
-
Li, D.F.1
Jiang, P.2
Zhu, D.Y.3
Hu, Y.4
Max, M.5
Wang, D.C.6
-
64
-
-
0030194456
-
Taste reception
-
Lindemann B. Taste reception. Physiol. Rev. 1996, 76:718-766.
-
(1996)
Physiol. Rev.
, vol.76
, pp. 718-766
-
-
Lindemann, B.1
-
65
-
-
0032959395
-
Receptor seeks ligand, on the way to cloning the molecular receptors for sweet and bitter taste
-
Lindemann B. Receptor seeks ligand, on the way to cloning the molecular receptors for sweet and bitter taste. Nat. Med. 1999, 5:381-382.
-
(1999)
Nat. Med.
, vol.5
, pp. 381-382
-
-
Lindemann, B.1
-
66
-
-
0035855939
-
Receptors and transduction in taste
-
Lindemann B. Receptors and transduction in taste. Nature 2001, 413:219-225.
-
(2001)
Nature
, vol.413
, pp. 219-225
-
-
Lindemann, B.1
-
67
-
-
0027530456
-
Purification, complete amino acid sequence and structural characterization of the heat-stable sweet protein, mabinlin II
-
Liu X., Maeda S., Hu Z., Aiuchi T., Nakaya K., Kurihara Y. Purification, complete amino acid sequence and structural characterization of the heat-stable sweet protein, mabinlin II. Eur. J. Biochem. 1993, 211:281-287.
-
(1993)
Eur. J. Biochem.
, vol.211
, pp. 281-287
-
-
Liu, X.1
Maeda, S.2
Hu, Z.3
Aiuchi, T.4
Nakaya, K.5
Kurihara, Y.6
-
68
-
-
0024398994
-
The genetics of tasting in mice, VI. Saccharin, acesulfame, dulcin and sucrose
-
Lush I. The genetics of tasting in mice, VI. Saccharin, acesulfame, dulcin and sucrose. Genet. Res. 1989, 53:95-99.
-
(1989)
Genet. Res.
, vol.53
, pp. 95-99
-
-
Lush, I.1
-
69
-
-
0028807124
-
The genetics of tasting in mice. VII. Glycine revisited, and the chromosomal location of Sac and Soa
-
Lush I., Hornigold N., King P., Stoye J. The genetics of tasting in mice. VII. Glycine revisited, and the chromosomal location of Sac and Soa. Genet. Res. 1995, 66:167-174.
-
(1995)
Genet. Res.
, vol.66
, pp. 167-174
-
-
Lush, I.1
Hornigold, N.2
King, P.3
Stoye, J.4
-
70
-
-
4043162667
-
The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant
-
Lyall V., Heck G.L., Vinnikova A.K., Ghosh S., Phan T.H., Alam R.I., et al. The mammalian amiloride-insensitive non-specific salt taste receptor is a vanilloid receptor-1 variant. J. Physiol. 2004, 558:147-159.
-
(2004)
J. Physiol.
, vol.558
, pp. 147-159
-
-
Lyall, V.1
Heck, G.L.2
Vinnikova, A.K.3
Ghosh, S.4
Phan, T.H.5
Alam, R.I.6
-
71
-
-
27244449766
-
Structure-sweetness relationship in egg white lysozyme, role of lysine and arginine residues on the elicitation of lysozyme sweetness
-
Masuda T., Ide N., Kitabatake N. Structure-sweetness relationship in egg white lysozyme, role of lysine and arginine residues on the elicitation of lysozyme sweetness. Chem. Senses 2005, 30:667-681.
-
(2005)
Chem. Senses
, vol.30
, pp. 667-681
-
-
Masuda, T.1
Ide, N.2
Kitabatake, N.3
-
72
-
-
0034611738
-
A family of candidate taste receptors in human and mouse
-
Matsunami H., Montmayeur J.P., Buck L.B. A family of candidate taste receptors in human and mouse. Nature 2000, 404:601-604.
-
(2000)
Nature
, vol.404
, pp. 601-604
-
-
Matsunami, H.1
Montmayeur, J.P.2
Buck, L.B.3
-
73
-
-
0035030731
-
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac
-
Max M., Shanker Y.G., Huang L., Rong M., Liu Z., Campagne F., et al. Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac. Nat. Genet. 2001, 28:58-63.
-
(2001)
Nat. Genet.
, vol.28
, pp. 58-63
-
-
Max, M.1
Shanker, Y.G.2
Huang, L.3
Rong, M.4
Liu, Z.5
Campagne, F.6
-
74
-
-
0141869933
-
Allosteric modulators of G-protein-coupled receptors
-
May L.T., Christopoulos A. Allosteric modulators of G-protein-coupled receptors. Curr. Opin. Pharmacol. 2003, 3:551-556.
-
(2003)
Curr. Opin. Pharmacol.
, vol.3
, pp. 551-556
-
-
May, L.T.1
Christopoulos, A.2
-
76
-
-
0026718951
-
Gustducin is a tastecell-specific G protein closely related to the transducins
-
McLaughlin S.K., McKinnon P.J., Margolskee R.F. Gustducin is a tastecell-specific G protein closely related to the transducins. Nature 1992, 357:563-569.
-
(1992)
Nature
, vol.357
, pp. 563-569
-
-
McLaughlin, S.K.1
McKinnon, P.J.2
Margolskee, R.F.3
-
77
-
-
0027993123
-
Molecular cloning of G proteins and phosphodiesterases from rat taste cells
-
McLaughlin S.K., McKinnon P.J., Spickofsky N., Danho W., Margolskee R.F. Molecular cloning of G proteins and phosphodiesterases from rat taste cells. Physiol. Behav. 1994, 56:1157-1164.
-
(1994)
Physiol. Behav.
, vol.56
, pp. 1157-1164
-
-
McLaughlin, S.K.1
McKinnon, P.J.2
Spickofsky, N.3
Danho, W.4
Margolskee, R.F.5
-
78
-
-
33845195004
-
Computational studies of ligand-receptor interactions in bitter taste receptors
-
Miguet L., Zhang Z., Grigorov M.G. Computational studies of ligand-receptor interactions in bitter taste receptors. J. Recept. Signal Transduct. Res. 2006, 26:611-630.
-
(2006)
J. Recept. Signal Transduct. Res.
, vol.26
, pp. 611-630
-
-
Miguet, L.1
Zhang, Z.2
Grigorov, M.G.3
-
79
-
-
0027959475
-
Brazzein, a new high-potency thermostable sweet protein from Pentadiplandra brazzeana B
-
Ming D., Hellekant G. Brazzein, a new high-potency thermostable sweet protein from Pentadiplandra brazzeana B. FEBS Lett. 1994, 355:106-108.
-
(1994)
FEBS Lett.
, vol.355
, pp. 106-108
-
-
Ming, D.1
Hellekant, G.2
-
81
-
-
0035041808
-
Candidate taste receptor gene near a sweet taste locus
-
Montmayeur J.P., Liberles S.D., Matsunami H., Buck L.B.A. Candidate taste receptor gene near a sweet taste locus. Nat. Neurosci. 2001, 4:492-498.
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 492-498
-
-
Montmayeur, J.P.1
Liberles, S.D.2
Matsunami, H.3
Buck, L.B.A.4
-
82
-
-
18844429747
-
Micro and macro models of the sweet receptor
-
Morini G., Temussi P.A. Micro and macro models of the sweet receptor. Chem. Senses 2005, 30:86-87.
-
(2005)
Chem. Senses
, vol.30
, pp. 86-87
-
-
Morini, G.1
Temussi, P.A.2
-
83
-
-
23944498549
-
From small sweeteners to sweet proteins, anatomy of the binding sites of the human T1R2-T1R3 receptor
-
Morini G., Bassoli A., Temussi P.A. From small sweeteners to sweet proteins, anatomy of the binding sites of the human T1R2-T1R3 receptor. J. Med. Chem. 2005, 48:5520-5529.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 5520-5529
-
-
Morini, G.1
Bassoli, A.2
Temussi, P.A.3
-
84
-
-
0017143048
-
Sweetening agents from natural sources
-
Morris J.A. Sweetening agents from natural sources. Lloydia 1976, 39:25-38.
-
(1976)
Lloydia
, vol.39
, pp. 25-38
-
-
Morris, J.A.1
-
85
-
-
0015526521
-
Purification of monellin, the sweet principle of Dioscoreophyllum cumminsii
-
Morris J.A., Cagan R.H. Purification of monellin, the sweet principle of Dioscoreophyllum cumminsii. Biochim. Biophys. Acta 1972, 261:114-122.
-
(1972)
Biochim. Biophys. Acta
, vol.261
, pp. 114-122
-
-
Morris, J.A.1
Cagan, R.H.2
-
86
-
-
0027162768
-
Sweet-tasting protein monellin is related to the cystatin family of thiol proteinase inhibitors
-
Murzin A.G. Sweet-tasting protein monellin is related to the cystatin family of thiol proteinase inhibitors. J. Mol. Biol. 1993, 230:689-694.
-
(1993)
J. Mol. Biol.
, vol.230
, pp. 689-694
-
-
Murzin, A.G.1
-
87
-
-
34247210665
-
Structures of the extracellular regions of the group II/III metabotropic glutamate receptors
-
Muto T., Tsuchiya D., Morikawa K., Jingami H. Structures of the extracellular regions of the group II/III metabotropic glutamate receptors. Proc. Natl. Acad. Sci. USA 2007, 104:3759-3764.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 3759-3764
-
-
Muto, T.1
Tsuchiya, D.2
Morikawa, K.3
Jingami, H.4
-
88
-
-
0035839040
-
Mammalian sweet taste receptors
-
Nelson G., Hoon M.A., Chandrashekar J., Zhang Y., Ryba N.J., Zuker C.S. Mammalian sweet taste receptors. Cell 2001, 106:381-390.
-
(2001)
Cell
, vol.106
, pp. 381-390
-
-
Nelson, G.1
Hoon, M.A.2
Chandrashekar, J.3
Zhang, Y.4
Ryba, N.J.5
Zuker, C.S.6
-
89
-
-
0034918672
-
Probing the surface of a sweet protein, NMR study of MNEI with a paramagnetic probe
-
Niccolai N., Spadaccini R., Scarselli M., Bernini A., Crescenzi O., Spiga F., et al. Probing the surface of a sweet protein, NMR study of MNEI with a paramagnetic probe. Protein Sci. 2001, 10:1498-1507.
-
(2001)
Protein Sci.
, vol.10
, pp. 1498-1507
-
-
Niccolai, N.1
Spadaccini, R.2
Scarselli, M.3
Bernini, A.4
Crescenzi, O.5
Spiga, F.6
-
90
-
-
0010428209
-
Preparation of (phenylguanidino)- and [[1-(phenylamino)ethyl]amino]acetic acids as sweeteners
-
1987, Chem. Abstr., 109, 190047k
-
Nofre C., Tinti J.-M., Chatzopoulos-Ouar F. Preparation of (phenylguanidino)- and [[1-(phenylamino)ethyl]amino]acetic acids as sweeteners. Eur. Pat. Appl. EP 1988, 241:395. 1987, Chem. Abstr., 109, 190047k.
-
(1988)
Eur. Pat. Appl. EP
, vol.241
, pp. 395
-
-
Nofre, C.1
Tinti, J.-M.2
Chatzopoulos-Ouar, F.3
-
91
-
-
0027096460
-
Crystal structure of a sweet tasting protein thaumatin I, at 1.65 A resolution
-
Ogata C.M., Gordon P.F., de Vos A.M., Kim S.H. Crystal structure of a sweet tasting protein thaumatin I, at 1.65 A resolution. J. Mol. Biol. 1992, 228:893-908.
-
(1992)
J. Mol. Biol.
, vol.228
, pp. 893-908
-
-
Ogata, C.M.1
Gordon, P.F.2
de Vos, A.M.3
Kim, S.H.4
-
92
-
-
50549103804
-
Critical molecular regions for elicitation of the sweetness of the sweet-tasting protein thaumatin I
-
Ohta K., Masuda T., Ide N., Kitabatake N. Critical molecular regions for elicitation of the sweetness of the sweet-tasting protein thaumatin I. FEBS J. 2008, 275:3644-3652.
-
(2008)
FEBS J.
, vol.275
, pp. 3644-3652
-
-
Ohta, K.1
Masuda, T.2
Ide, N.3
Kitabatake, N.4
-
93
-
-
77953231314
-
Functional hypothesis on miraculin' sweetness by a molecular dynamics approach
-
Paladino A., Colonna G., Facchiano A.M., Costantini S. Functional hypothesis on miraculin' sweetness by a molecular dynamics approach. Biochem. Biophys. Res. Commun. 2010, 396:726-730.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.396
, pp. 726-730
-
-
Paladino, A.1
Colonna, G.2
Facchiano, A.M.3
Costantini, S.4
-
94
-
-
0025026058
-
Comparison of the structures of globins and phycocyanins: evidence for evolutionary relationship
-
Pastore A., Lesk A.M. Comparison of the structures of globins and phycocyanins: evidence for evolutionary relationship. Proteins Struct. Funct. Genet. 1990, 8:133-155.
-
(1990)
Proteins Struct. Funct. Genet.
, vol.8
, pp. 133-155
-
-
Pastore, A.1
Lesk, A.M.2
-
95
-
-
0038662595
-
Evolution, structure, and activation mechanism of family 3/CG-protein-coupled receptors
-
Pin J.P., Galvez T., Prezeau L. Evolution, structure, and activation mechanism of family 3/CG-protein-coupled receptors. Pharmacol. Ther. 2003, 98:325-354.
-
(2003)
Pharmacol. Ther.
, vol.98
, pp. 325-354
-
-
Pin, J.P.1
Galvez, T.2
Prezeau, L.3
-
96
-
-
0026641087
-
New aspartame-like sweeteners containing l-(Me)Phe
-
Polinelli S., Broxterman Q.B., Schoemaker H.E., Boesten W.H.J., Crisma M., Valle G., et al. New aspartame-like sweeteners containing l-(Me)Phe. Bioorg. Med. Chem. Lett. 1992, 2:453-456.
-
(1992)
Bioorg. Med. Chem. Lett.
, vol.2
, pp. 453-456
-
-
Polinelli, S.1
Broxterman, Q.B.2
Schoemaker, H.E.3
Boesten, W.H.J.4
Crisma, M.5
Valle, G.6
-
97
-
-
0035023861
-
Identification of a novel member of the T1R family of putative taste receptors
-
Sainz E., Korley J.N., Battey J.F., Sullivan S.L. Identification of a novel member of the T1R family of putative taste receptors. J. Neurochem. 2001, 77:896-903.
-
(2001)
J. Neurochem.
, vol.77
, pp. 896-903
-
-
Sainz, E.1
Korley, J.N.2
Battey, J.F.3
Sullivan, S.L.4
-
98
-
-
0027136282
-
Comparative protein modeling by satisfaction of spatial restraints
-
Sali A., Blundell T.L. Comparative protein modeling by satisfaction of spatial restraints. J. Mol. Biol. 1993, 234:779-815.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
99
-
-
33644552461
-
Cloning and characterization of a novel mGluR1 variant from vallate papillae that functions as a receptor for l-glutamate stimuli
-
San Gabriel A., Uneyama H., Yoshie S., Torii K. Cloning and characterization of a novel mGluR1 variant from vallate papillae that functions as a receptor for l-glutamate stimuli. Chem. Senses 2005, 30:i25-i26.
-
(2005)
Chem. Senses
, vol.30
-
-
San Gabriel, A.1
Uneyama, H.2
Yoshie, S.3
Torii, K.4
-
101
-
-
77949529410
-
Positive allosteric modulators of the human sweet taste receptor enhance sweet taste
-
Servant G., Tachdjian C., Tang X.Q., Werner S., Zhang F., Li X., et al. Positive allosteric modulators of the human sweet taste receptor enhance sweet taste. Proc. Natl. Acad. Sci. USA 2010, 107:4746-4751.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 4746-4751
-
-
Servant, G.1
Tachdjian, C.2
Tang, X.Q.3
Werner, S.4
Zhang, F.5
Li, X.6
-
102
-
-
0014192965
-
Molecular theory of sweet taste
-
Shallenberger R.S., Acree T. Molecular theory of sweet taste. Nature 1967, 216:480-482.
-
(1967)
Nature
, vol.216
, pp. 480-482
-
-
Shallenberger, R.S.1
Acree, T.2
-
103
-
-
0014667672
-
Sweet taste of d and l-sugars and amino-acids and the steric nature of their chemo-receptor site
-
Shallenberger R.S., Acree T.E., Lee C.Y. Sweet taste of d and l-sugars and amino-acids and the steric nature of their chemo-receptor site. Nature 1969, 221:555-556.
-
(1969)
Nature
, vol.221
, pp. 555-556
-
-
Shallenberger, R.S.1
Acree, T.E.2
Lee, C.Y.3
-
104
-
-
0028827454
-
Structure-taste correlations in sweet dihydrochalcone, sweet dihydroisocoumarin, and bitter flavone compounds
-
Shin W., Kim S.J., Shin J.M., Kim S.H. Structure-taste correlations in sweet dihydrochalcone, sweet dihydroisocoumarin, and bitter flavone compounds. J. Med. Chem. 1995, 38:4325-4331.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4325-4331
-
-
Shin, W.1
Kim, S.J.2
Shin, J.M.3
Kim, S.H.4
-
105
-
-
4544279330
-
Neoculin as a new taste-modifying protein occurring in the fruit of Curculigo latifolia
-
Shirasuka Y., Nakajima K., Asakura T., Yamashita H., Yamamoto A., Hata S., et al. Neoculin as a new taste-modifying protein occurring in the fruit of Curculigo latifolia. Biosci. Biotechnol. Biochem. 2004, 68:1403-1407.
-
(2004)
Biosci. Biotechnol. Biochem.
, vol.68
, pp. 1403-1407
-
-
Shirasuka, Y.1
Nakajima, K.2
Asakura, T.3
Yamashita, H.4
Yamamoto, A.5
Hata, S.6
-
106
-
-
0000323157
-
The taste of amino acids, peptides, and proteins
-
Solms J. The taste of amino acids, peptides, and proteins. J. Agric. Food Chem. 1969, 17:686-688.
-
(1969)
J. Agric. Food Chem.
, vol.17
, pp. 686-688
-
-
Solms, J.1
-
107
-
-
0013849766
-
The taste of l- and d-amino acids
-
Solms J., Vuataz L., Egli R.H. The taste of l- and d-amino acids. Experientia 1965, 21:692-694.
-
(1965)
Experientia
, vol.21
, pp. 692-694
-
-
Solms, J.1
Vuataz, L.2
Egli, R.H.3
-
108
-
-
0028966667
-
The taste-active regions of monellin, a potently sweet protein
-
Somoza J.R., Cho J.M., Kim S.H. The taste-active regions of monellin, a potently sweet protein. Chem. Senses 1995, 20:61-68.
-
(1995)
Chem. Senses
, vol.20
, pp. 61-68
-
-
Somoza, J.R.1
Cho, J.M.2
Kim, S.H.3
-
109
-
-
0035910268
-
Solution structure of a sweet protein, NMR study of MNEI, a single chain monellin
-
Spadaccini R., Crescenzi O., Tancredi T., De Casamassimi N., Saviano G., Scognamiglio R., et al. Solution structure of a sweet protein, NMR study of MNEI, a single chain monellin. J. Mol. Biol. 2001, 305:505-514.
-
(2001)
J. Mol. Biol.
, vol.305
, pp. 505-514
-
-
Spadaccini, R.1
Crescenzi, O.2
Tancredi, T.3
De Casamassimi, N.4
Saviano, G.5
Scognamiglio, R.6
-
110
-
-
0037414437
-
The mechanism of interaction of sweet proteins with the T1R2-T1R3 receptor, evidence from the solution structure of G16A-MNEI
-
Spadaccini R., Trabucco F., Saviano G., Picone D., Crescenzi O., Tancredi T., et al. The mechanism of interaction of sweet proteins with the T1R2-T1R3 receptor, evidence from the solution structure of G16A-MNEI. J. Mol. Biol. 2003, 328:683-692.
-
(2003)
J. Mol. Biol.
, vol.328
, pp. 683-692
-
-
Spadaccini, R.1
Trabucco, F.2
Saviano, G.3
Picone, D.4
Crescenzi, O.5
Tancredi, T.6
-
111
-
-
0035375110
-
Solution structure, backbone dynamics, and stability of a double mutant single-chain monellin. structural origin of sweetness
-
Sung Y.H., Shin J., Chang H.J., Cho J.M., Lee W. Solution structure, backbone dynamics, and stability of a double mutant single-chain monellin. structural origin of sweetness. J. Biol. Chem. 2001, 276:19624-19630.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19624-19630
-
-
Sung, Y.H.1
Shin, J.2
Chang, H.J.3
Cho, J.M.4
Lee, W.5
-
112
-
-
4344594261
-
Recombinant curculin heterodimer exhibits taste-modifying and sweet-tasting activities
-
Suzuki M., Kurimoto E., Nirasawa S., Masuda Y., Hori K., Kurihara Y., et al. Recombinant curculin heterodimer exhibits taste-modifying and sweet-tasting activities. FEBS Lett. 2004, 573:135-138.
-
(2004)
FEBS Lett.
, vol.573
, pp. 135-138
-
-
Suzuki, M.1
Kurimoto, E.2
Nirasawa, S.3
Masuda, Y.4
Hori, K.5
Kurihara, Y.6
-
113
-
-
0018583620
-
Three-dimensional mapping of the bitter taste receptor site
-
Tancredi T.T., Lelj F., Temussi P.A. Three-dimensional mapping of the bitter taste receptor site. Chem. Senses Flav. 1979, 4:259-264.
-
(1979)
Chem. Senses Flav.
, vol.4
, pp. 259-264
-
-
Tancredi, T.T.1
Lelj, F.2
Temussi, P.A.3
-
114
-
-
0026781281
-
Structural determination of the active site of a sweet protein, a 1H NMR investigation of MNEI
-
Tancredi T., Iijima H., Saviano G., Amodeo P., Temussi P.A. Structural determination of the active site of a sweet protein, a 1H NMR investigation of MNEI. FEBS Lett. 1992, 310:27-30.
-
(1992)
FEBS Lett.
, vol.310
, pp. 27-30
-
-
Tancredi, T.1
Iijima, H.2
Saviano, G.3
Amodeo, P.4
Temussi, P.A.5
-
115
-
-
2942574363
-
Interaction of sweet proteins with their receptor. A conformational study of peptides corresponding to loops of brazzein, monellin and thaumatin
-
Tancredi T., Pastore A., Salvatori S., Esposito V., Temussi P.A. Interaction of sweet proteins with their receptor. A conformational study of peptides corresponding to loops of brazzein, monellin and thaumatin. Eur. J. Biochem. 2004, 271:2231-2240.
-
(2004)
Eur. J. Biochem.
, vol.271
, pp. 2231-2240
-
-
Tancredi, T.1
Pastore, A.2
Salvatori, S.3
Esposito, V.4
Temussi, P.A.5
-
116
-
-
0037189912
-
Why are sweet proteins sweet? Interaction of brazzein, monellin and thaumatin with the T1R2-T1R3 receptor
-
Temussi P.A. Why are sweet proteins sweet? Interaction of brazzein, monellin and thaumatin with the T1R2-T1R3 receptor. FEBS Lett. 2002, 526:1-3.
-
(2002)
FEBS Lett.
, vol.526
, pp. 1-3
-
-
Temussi, P.A.1
-
117
-
-
33747309084
-
Natural sweet macromolecules: how sweet proteins work
-
Temussi P.A. Natural sweet macromolecules: how sweet proteins work. Cell. Mol. Life Sci. 2006, 63:1876-1888.
-
(2006)
Cell. Mol. Life Sci.
, vol.63
, pp. 1876-1888
-
-
Temussi, P.A.1
-
118
-
-
34748919072
-
The sweet taste receptor: a single receptor with multiple sites and modes of interaction
-
Temussi P.A. The sweet taste receptor: a single receptor with multiple sites and modes of interaction. Adv. Food Nutr. Res 2007, 53:199-239.
-
(2007)
Adv. Food Nutr. Res
, vol.53
, pp. 199-239
-
-
Temussi, P.A.1
-
119
-
-
67149138301
-
Sweet, bitter and umami receptors: a complex relationship
-
Temussi P.A. Sweet, bitter and umami receptors: a complex relationship. Trends Biochem. Sci. 2009, 34:296-302.
-
(2009)
Trends Biochem. Sci.
, vol.34
, pp. 296-302
-
-
Temussi, P.A.1
-
120
-
-
80054786032
-
Determinants of sweetness in proteins: a topological approach
-
in press
-
Temussi P.A. Determinants of sweetness in proteins: a topological approach. J. Mol. Recogn. 2011, in press.
-
(2011)
J. Mol. Recogn.
-
-
Temussi, P.A.1
-
121
-
-
0018182134
-
Three-dimensional mapping of the sweet taste receptor site
-
Temussi P.A., Lelj F., Tancredi T. Three-dimensional mapping of the sweet taste receptor site. J. Med. Chem. 1978, 21:1154-1158.
-
(1978)
J. Med. Chem.
, vol.21
, pp. 1154-1158
-
-
Temussi, P.A.1
Lelj, F.2
Tancredi, T.3
-
122
-
-
84987159696
-
Soft agonist-receptor interactions, theoretical and experimental simulation of the active site of the receptor site of sweet molecules
-
Temussi P.A., Lelj F., Tancredi T., Castiglione-Morelli M.A., Pastore A. Soft agonist-receptor interactions, theoretical and experimental simulation of the active site of the receptor site of sweet molecules. Int. J. Quantum Chem. 1984, 26:889-906.
-
(1984)
Int. J. Quantum Chem.
, vol.26
, pp. 889-906
-
-
Temussi, P.A.1
Lelj, F.2
Tancredi, T.3
Castiglione-Morelli, M.A.4
Pastore, A.5
-
123
-
-
0024288401
-
Complete purification and characterization of the taste-modifying protein, miraculin, from miracle fruit
-
Theerasilp S., Kurihara Y. Complete purification and characterization of the taste-modifying protein, miraculin, from miracle fruit. J. Biol. Chem. 1988, 263:11536-11539.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 11536-11539
-
-
Theerasilp, S.1
Kurihara, Y.2
-
124
-
-
0024533487
-
Complete amino acid sequence and structure characterization of the taste-modifying protein, miraculin
-
Theerasilp S., Hitotsuya H., Nakajo S., Nakaya K., Nakamura Y., Kurihara Y. Complete amino acid sequence and structure characterization of the taste-modifying protein, miraculin. J. Biol. Chem. 1989, 264:6655-6659.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 6655-6659
-
-
Theerasilp, S.1
Hitotsuya, H.2
Nakajo, S.3
Nakaya, K.4
Nakamura, Y.5
Kurihara, Y.6
-
125
-
-
0027968068
-
CLUSTAL_W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
-
Thompson J.D., Higgins D.G., Gibson T.J. CLUSTAL_W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 1994, 22:4673-4680.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 4673-4680
-
-
Thompson, J.D.1
Higgins, D.G.2
Gibson, T.J.3
-
126
-
-
0031574072
-
The CLUSTAL_X windows interface, flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., Higgins D.G. The CLUSTAL_X windows interface, flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 1997, 24:4876-4882.
-
(1997)
Nucleic Acids Res.
, vol.24
, pp. 4876-4882
-
-
Thompson, J.D.1
Gibson, T.J.2
Plewniak, F.3
Jeanmougin, F.4
Higgins, D.G.5
-
127
-
-
0002455549
-
Why does a sweetener taste sweet? A new model
-
ACS Symposium Series, ACS, Washington, DC, D.E. Walters, F.T. Orthofer, G.E. DuBois (Eds.)
-
Tinti J.M., Nofre C. Why does a sweetener taste sweet? A new model. Sweeteners, Discovery, Molecular Design and Chemoreception 1991, vol. 450:88-99. ACS Symposium Series, ACS, Washington, DC. D.E. Walters, F.T. Orthofer, G.E. DuBois (Eds.).
-
(1991)
Sweeteners, Discovery, Molecular Design and Chemoreception
, vol.450
, pp. 88-99
-
-
Tinti, J.M.1
Nofre, C.2
-
128
-
-
35148813068
-
Breadth of tuning and taste coding in mammalian taste buds
-
Tomchik S.M., Berg S., Kim J.W., Chaudhari N., Roper S.D. Breadth of tuning and taste coding in mammalian taste buds. J. Neurosci. 2007, 27:10840-10848.
-
(2007)
J. Neurosci.
, vol.27
, pp. 10840-10848
-
-
Tomchik, S.M.1
Berg, S.2
Kim, J.W.3
Chaudhari, N.4
Roper, S.D.5
-
129
-
-
0037022586
-
Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+
-
Tsuchiya D., Kunishima N., Kamiya N., Jingami H., Morikawa K. Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+. Proc. Natl. Acad. Sci. USA 2002, 99:2660-2665.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2660-2665
-
-
Tsuchiya, D.1
Kunishima, N.2
Kamiya, N.3
Jingami, H.4
Morikawa, K.5
-
130
-
-
0028984540
-
Protein docking for low-resolution structures
-
Vakser I.A. Protein docking for low-resolution structures. Protein Eng. 1995, 8:371-377.
-
(1995)
Protein Eng.
, vol.8
, pp. 371-377
-
-
Vakser, I.A.1
-
131
-
-
0033587727
-
A systematic study of low-resolution recognition in protein-protein complexes
-
Vakser I.A., Matar O.G., Lam C.F. A systematic study of low-resolution recognition in protein-protein complexes. Proc. Natl. Acad. Sci. USA 1999, 96:8477-8482.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8477-8482
-
-
Vakser, I.A.1
Matar, O.G.2
Lam, C.F.3
-
132
-
-
0015494327
-
Isolation and characterization of thaumatin I and II, the sweet-tasting proteins from Thaumatococcus daniellii Benth
-
van der Wel H., Loeve K. Isolation and characterization of thaumatin I and II, the sweet-tasting proteins from Thaumatococcus daniellii Benth. Eur. J. Biochem. 1972, 31:221-225.
-
(1972)
Eur. J. Biochem.
, vol.31
, pp. 221-225
-
-
van der Wel, H.1
Loeve, K.2
-
133
-
-
0029135744
-
Pseudoreceptor modelling, the construction of three dimensional receptor surrogates
-
Vedani A., Zbinden P., Snyder J.P., Greenidge P.A. Pseudoreceptor modelling, the construction of three dimensional receptor surrogates. J. Am. Chem. Soc. 1995, 117:4987-4994.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 4987-4994
-
-
Vedani, A.1
Zbinden, P.2
Snyder, J.P.3
Greenidge, P.A.4
-
134
-
-
0014263324
-
On organic compounds with a sweet and/or a bitter taste Il Farmaco
-
Verkade P.E. On organic compounds with a sweet and/or a bitter taste Il Farmaco. Farmaco. Sci. 1967, 23:248-291.
-
(1967)
Farmaco. Sci.
, vol.23
, pp. 248-291
-
-
Verkade, P.E.1
-
135
-
-
33751156382
-
Using models to understand and design sweeteners
-
Walters D.E. Using models to understand and design sweeteners. J. Chem. Educ. 1995, 72:680-683.
-
(1995)
J. Chem. Educ.
, vol.72
, pp. 680-683
-
-
Walters, D.E.1
-
136
-
-
0036664529
-
Homology-based model of the extracellular domain of the taste receptor T1R3
-
Walters D.E. Homology-based model of the extracellular domain of the taste receptor T1R3. Pure Appl. Chem. 2002, 74:1117-1123.
-
(2002)
Pure Appl. Chem.
, vol.74
, pp. 1117-1123
-
-
Walters, D.E.1
-
137
-
-
33846489813
-
Interactions of the sweet protein brazzein with the sweet taste receptor
-
Walters D.E., Hellekant G. Interactions of the sweet protein brazzein with the sweet taste receptor. J. Agric. Food Chem. 2006, 54:10129-10133.
-
(2006)
J. Agric. Food Chem.
, vol.54
, pp. 10129-10133
-
-
Walters, D.E.1
Hellekant, G.2
-
139
-
-
0040855786
-
Dihydrochalcones; their occurrence and use as indicators in chemical plant taxonomy
-
Williams A.H. Dihydrochalcones; their occurrence and use as indicators in chemical plant taxonomy. Nature 1964, 202:824-825.
-
(1964)
Nature
, vol.202
, pp. 824-825
-
-
Williams, A.H.1
-
140
-
-
0025126845
-
Purification and complete amino acid sequence of a new type of sweet protein taste-modifying activity, curculin
-
Yamashita H., Theerasilp S., Aiuchi T., Nakaya K., Nakamura Y., Kurihara Y. Purification and complete amino acid sequence of a new type of sweet protein taste-modifying activity, curculin. J. Biol. Chem. 1990, 265:15770-15775.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 15770-15775
-
-
Yamashita, H.1
Theerasilp, S.2
Aiuchi, T.3
Nakaya, K.4
Nakamura, Y.5
Kurihara, Y.6
-
141
-
-
58549099473
-
Molecular mechanism for the umami taste synergism
-
Zhang F., Klebansky B., Fine R.M., Xu H., Pronin A., Liu H., et al. Molecular mechanism for the umami taste synergism. Proc. Natl. Acad. Sci. USA 2008, 105:20930-20934.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20930-20934
-
-
Zhang, F.1
Klebansky, B.2
Fine, R.M.3
Xu, H.4
Pronin, A.5
Liu, H.6
|