A candidate taste receptor gene near a sweet taste locus

Nature Neuroscience

Volumn 4, Issue 5, 2001, Pages 492-498

  Montmayeur, J P ^a   Liberles, S D ^a   Matsunami, H ^a   Buck, L B ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DIMER; GENE PRODUCT; LIGAND; PROTEIN T1R3; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; GENE EXPRESSION; GENE LOCATION; GENE LOCUS; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; SEQUENCE ANALYSIS; SWEETNESS; TASTE BUD; TASTE DISCRIMINATION;

EID: 0035041808     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/87440     Document Type: Article

References (50)

1. Taste reception
2. Cellular mechanisms of taste transduction
3. The molecular physiology of taste transduction
4. Transduction of bitter and sweet taste by gustducin
5. A plethora of taste receptors
6. A metabotropic glutamate receptor variant functions as a taste receptor
7. A novel family of mammalian taste receptors
8. A family of candidate taste receptors in human and mouse
9. T2Rs function as bitter taste receptors
10. Molecular identification of a taste receptor gene for trehalose in Drosophila
11. Putative mammalian taste receptors: A class of taste-specific GPCRs with distinct topographic selectivity
12. Gene mapping for taste related phenotypes in human and mice
13. Single-locus control of saccharin preference in mice
14. The genetics of tasting in mice: VI. Saccharin, acesulfame, dulcin and sucrose
15. The genetics of tasting in mice. VII. Glycine revisited, and the chromosomal location of Sac and Soa
16. The genetic basis of preference for sweet substances among inbred strains of mice: Preference ratio phenotypes and the alleles of the Sac and dpa loci
17. Sucrose consumption in mice: Major influence of two genetic loci affecting peripheral sensory responses
18. Quantitative trait loci associated with short-term intake of sucrose saccharin and quinine solutions in laboratory mice
19. Single locus control of saccharin intake in BXD/Ty recombinant inbred (RI) mice: Some methodological implications for RI strain analysis
20. Chorda tympani responses in two inbred strains of mice with different taste preferences
21. 2+-sensing receptor from bovine parathyroid
22. A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution
23. A multigene family encoding a diverse array of putative pheromone receptors in mammals
24. A new multigene family of putative pheromone receptors
25. Role of the large extracellular domain of metabotropic glutamate receptors in agonist selectivity determination
26. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor
27. A first-generation whole genome-radiation hybrid map spanning the mouse genome
28. Molecular markers that define the distal end of mouse autosomes 4, 13, and 19 and the sex chromosomes
29. The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8
30. Mapping of clone D4Smh6b to the distal end of mouse chromosome 4
31. High-resolution genetic mapping of the saccharin preference locus (Sac) and the putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal Chromosome 4
32. Structure and function of the extracellular calcium-sensing receptor
33. Genetic influences on saccharin preference of mice
34. Genetic influence on water and sweetened water consumption in mice
35. Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells
36. Characterization and solubilization of bitter-responsive receptors that couple to gustducin
37. B receptors - The first 7TM heterodimers
38. 2+ in response to sugars and non-sugar sweeteners in transduction of sweet taste in the rat
39. Olfactory receptor trafficking involves conserved regulatory steps
40. Sweet taste involves several distinct receptor mechanisms
41. Evolution of the sweetness receptor in primates. I. Why does alitame taste sweet in all prosimians and simians, and aspartame only in old world simians?
42. Evolution of the sweetness receptor in primates. II. Gustatory responses of non-human primates to nine compounds known to be sweet in man
43. Multiple human taste receptor sites: A molecular modeling approach
44. Lack of gurmarin sensitivity of sweet taste receptors innervated by the glossopharyngeal nerve in C57BL mice
45. Sweet taste response of mouse chorda tympani neurons: Existence of gurmarin-sensitive and -insensitive receptor components
46. Multiple receptor sites mediate sweetness: Evidence from cross adaptation
47. Cross-adaptation and molecular modeling study of receptor mechanisms common to four taste stimuli in humans
48. Cross-adapted sugar responses in the mouse taste cell
49. Sensory transduction in vomeronasal neurons: Evidence for G alpha o, G alpha i2, and adenylyl cyclase II as major components of a pheromone signaling cascade
50. Combinatorial receptor codes for odors