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Biochemistry (Moscow)
Volumn 76, Issue 9, 2011, Pages 981-998
Role of Epac proteins in mechanisms of cAMP-dependent immunoregulation
Author keywords

B lymphocytes; Epac proteins; monocytes macrophages; T lymphocytes
Indexed keywords

BACTERIA (MICROORGANISMS);
EID: 80054739836     PISSN: 00062979     EISSN: 16083040     Source Type: Journal    
DOI: 10.1134/S000629791109001X     Document Type: Review
Times cited : (14)
References (175)
  • 1
    • 0038199731 scopus 로고    scopus 로고
    • CAMP effector mechanisms. Novel twists for an 'old' signaling system
    • DOI 10.1016/S0014-5793(03)00563-5
    • R. Kopperud C. Krakstad F. Selheim S. O. Doskeland 2003 FEBS Lett. 546 121 126 12829247 1:CAS:528:DC%2BD3sXkvVKjs7c%3D 10.1016/S0014-5793(03)00563-5 (Pubitemid 36782292)
    • (2003) FEBS Letters , vol.546 , Issue.1 , pp. 121-126
    • Kopperud, R.1    Krakstad, C.2    Selheim, F.3    Doskeland, S.O.4
  • 3
    • 0141541343 scopus 로고    scopus 로고
    • 14993377 1:CAS:528:DC%2BD3sXpsVWg 10.1124/mi.2.3.168
    • R. K. Sunahara R. Taussig 2002 Mol. Interv. 2 168 184 14993377 1:CAS:528:DC%2BD3sXpsVWg 10.1124/mi.2.3.168
    • (2002) Mol. Interv. , vol.2 , pp. 168-184
    • Sunahara, R.K.1    Taussig, R.2
  • 4
    • 70350469968 scopus 로고    scopus 로고
    • 19684092 1:CAS:528:DC%2BD1MXhtlOqtbjP 10.1124/mol.109.059345
    • C. W. Dessauer 2009 Mol. Pharmacol. 76 935 941 19684092 1:CAS:528:DC%2BD1MXhtlOqtbjP 10.1124/mol.109.059345
    • (2009) Mol. Pharmacol. , vol.76 , pp. 935-941
    • Dessauer, C.W.1
  • 5
    • 54249153754 scopus 로고    scopus 로고
    • 18948702 1:CAS:528:DC%2BD1MXhslyit78%3D 10.1159/000166277
    • R. Sadana C. W. Dessauer 2009 Neurosignals 17 5 22 18948702 1:CAS:528:DC%2BD1MXhslyit78%3D 10.1159/000166277
    • (2009) Neurosignals , vol.17 , pp. 5-22
    • Sadana, R.1    Dessauer, C.W.2
  • 8
    • 0037443097 scopus 로고    scopus 로고
    • PDE4 cAMP phosphodiesterases: Modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization
    • DOI 10.1042/BJ20021698
    • M. D. Hoslay D. R. Adams 2003 Biochem. J. 370 1 18 10.1042/BJ20021698 1:CAS:528:DC%2BD3sXhtVKktbc%3D (Pubitemid 36259414)
    • (2003) Biochemical Journal , vol.370 , Issue.1 , pp. 1-18
    • Houslay, M.D.1    Adams, D.R.2
  • 10
    • 33847068206 scopus 로고    scopus 로고
    • 17307970 1:CAS:528:DC%2BD2sXhsF2kurY%3D 10.1161/01.RES.0000256354.95791. f1
    • K. Omori J. Kotera 2007 Circ. Res. 100 309 327 17307970 1:CAS:528:DC%2BD2sXhsF2kurY%3D 10.1161/01.RES.0000256354.95791.f1
    • (2007) Circ. Res. , vol.100 , pp. 309-327
    • Omori, K.1    Kotera, J.2
  • 11
    • 20444412702 scopus 로고    scopus 로고
    • Compartmentalisation of phosphodiesterases and protein kinase A: Opposites attract
    • DOI 10.1016/j.febslet.2005.03.089, PII S0014579305004515
    • G. S. Baillie J. D. Scott M. D. Houslay 2005 FEBS Lett. 579 3264 3270 15943971 1:CAS:528:DC%2BD2MXltFSqurc%3D 10.1016/j.febslet.2005.03.089 (Pubitemid 40804673)
    • (2005) FEBS Letters , vol.579 , Issue.15 , pp. 3264-3270
    • Baillie, G.S.1    Scott, J.D.2    Houslay, M.D.3
  • 12
    • 0036729478 scopus 로고    scopus 로고
    • Cyclic nucleotide research - Still expanding after half a century
    • DOI 10.1038/nrm911
    • J. A. Beavo L. L. Brunton 2002 Nat. Rev. Mol. Cell. Biol. 3 710 718 12209131 1:CAS:528:DC%2BD38Xmslansrk%3D 10.1038/nrm911 (Pubitemid 34987792)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.9 , pp. 710-718
    • Beavo, J.A.1    Brunton, L.L.2
  • 15
    • 0032484019 scopus 로고    scopus 로고
    • CREB is a regulatory target for the protein kinase Akt/PKB
    • DOI 10.1074/jbc.273.49.32377
    • K. Du M. Montminy 1998 J. Biol. Chem. 273 32377 32379 9829964 1:CAS:528:DyaK1cXnvFOnsLY%3D 10.1074/jbc.273.49.32377 (Pubitemid 28557606)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.49 , pp. 32377-32379
    • Du, K.1    Montminy, M.2
  • 17
    • 80054718711 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD28XivVemur0%3D
    • S. V. Shirshev 2005 Usp. Sovrem. Biol. 125 555 566 1:CAS:528: DC%2BD28XivVemur0%3D
    • (2005) Usp. Sovrem. Biol. , vol.125 , pp. 555-566
    • Shirshev, S.V.1
  • 18
    • 80054758295 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BD2sXhsVSjtLvM
    • S. V. Shirshev 2007 Usp. Sovrem. Biol. 127 358 371 1:CAS:528: DC%2BD2sXhsVSjtLvM
    • (2007) Usp. Sovrem. Biol. , vol.127 , pp. 358-371
    • Shirshev, S.V.1
  • 19
    • 80054752678 scopus 로고    scopus 로고
    • 1:CAS:528:DC%2BC3cXosF2kurY%3D
    • S. V. Shirshev 2010 Usp. Sovrem. Biol. 130 130 146 1:CAS:528: DC%2BC3cXosF2kurY%3D
    • (2010) Usp. Sovrem. Biol. , vol.130 , pp. 130-146
    • Shirshev, S.V.1
  • 23
    • 0029045679 scopus 로고
    • 8562314 1:CAS:528:DyaK2MXnvVaitr8%3D 10.1016/0898-6568(95)00023-I
    • T. Kaneko R. Alvarez I. F. Ueki J. A. Nadel 1995 Cell Signal. 7 527 534 8562314 1:CAS:528:DyaK2MXnvVaitr8%3D 10.1016/0898-6568(95)00023-I
    • (1995) Cell Signal. , vol.7 , pp. 527-534
    • Kaneko, T.1    Alvarez, R.2    Ueki, I.F.3    Nadel, J.A.4
  • 25
    • 13544251389 scopus 로고    scopus 로고
    • Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: A novel role for the cAMP pathway
    • DOI 10.1182/blood-2004-05-1718
    • M. Schnurr T. Toy A. Shin M. Wagner J. Cebon E. Maraskovsky 2005 Blood 105 1582 1589 15486065 1:CAS:528:DC%2BD2MXhsVChtbg%3D 10.1182/blood-2004-05-1718 (Pubitemid 40223678)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1582-1589
    • Schnurr, M.1    Toy, T.2    Shin, A.3    Wagner, M.4    Cebon, J.5    Maraskovsky, E.6
  • 27
    • 34347369084 scopus 로고    scopus 로고
    • Post-translational modifications and regulation of the RAS superfamily of GTPases as anticancer targets
    • DOI 10.1038/nrd2221, PII NRD2221
    • P. A. Konstantinopoulos M. V. Karamouzis A. G. Papavassilou 2007 Nat. Rev. Drug Disc. 6 541 553 1:CAS:528:DC%2BD2sXntVOksrc%3D 10.1038/nrd2221 (Pubitemid 47019443)
    • (2007) Nature Reviews Drug Discovery , vol.6 , Issue.7 , pp. 541-555
    • Konstantinopoulos, P.A.1    Karamouzis, M.V.2    Papavassiliou, A.G.3
  • 29
    • 0036607064 scopus 로고    scopus 로고
    • Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation
    • DOI 10.1016/S0962-8924(02)02294-8, PII S0962892402022948
    • P. J. S. Stork J. M. Schmitt 2002 Trends Cell Biol. 12 258 266 12074885 1:CAS:528:DC%2BD38Xks1emuro%3D 10.1016/S0962-8924(02)02294-8 (Pubitemid 34634174)
    • (2002) Trends in Cell Biology , vol.12 , Issue.6 , pp. 258-266
    • Stork, P.J.S.1    Schmitt, J.M.2
  • 36
    • 0033021636 scopus 로고    scopus 로고
    • AKAPs: From structure to function
    • DOI 10.1016/S0962-8924(99)01558-5, PII S0962892499015585
    • M. Colledge J. D. Scott 1999 Trends Cell Biol. 9 216 221 10354567 1:CAS:528:DyaK1MXjvFOrurk%3D 10.1016/S0962-8924(99)01558-5 (Pubitemid 29244132)
    • (1999) Trends in Cell Biology , vol.9 , Issue.6 , pp. 216-221
    • Colledge, M.1    Scott, J.D.2
  • 37
    • 0041836339 scopus 로고    scopus 로고
    • Epac: A new cAMP target and new avenues in cAMP research
    • DOI 10.1038/nrm1197
    • J. L. Bos 2003 Nat. Rev. Mol. Cell Biol. 4 733 738 14506476 1:CAS:528:DC%2BD3sXnsVKqsLw%3D 10.1038/nrm1197 (Pubitemid 37082188)
    • (2003) Nature Reviews Molecular Cell Biology , vol.4 , Issue.9 , pp. 733-738
    • Bos, J.L.1
  • 40
    • 33751241720 scopus 로고    scopus 로고
    • Epac proteins: multi-purpose cAMP targets
    • DOI 10.1016/j.tibs.2006.10.002, PII S0968000406002921
    • J. L. Bos 2006 Trends Biochem. Sci. 31 680 686 17084085 1:CAS:528:DC%2BD28Xht1ClsrfF 10.1016/j.tibs.2006.10.002 (Pubitemid 44791945)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.12 , pp. 680-686
    • Bos, J.L.1
  • 42
    • 1642296250 scopus 로고    scopus 로고
    • Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis
    • DOI 10.1182/blood-2003-06-2154
    • S. Tiwari K. Felekkis E. Y. Moon A. Flies D. H. Sherr A. Lerner 2004 Blood 103 2661 2667 14615375 1:CAS:528:DC%2BD2cXjtVaks7c%3D 10.1182/blood-2003- 06-2154 (Pubitemid 38393022)
    • (2004) Blood , vol.103 , Issue.7 , pp. 2661-2667
    • Tlwari, S.1    Felekkis, K.2    Moon, E.-Y.3    Flies, A.4    Sherr, D.H.5    Lerner, A.6
  • 43
    • 0037135592 scopus 로고    scopus 로고
    • Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP
    • DOI 10.1074/jbc.M203571200
    • J. Qiao F. C. Mei V. L. Popov L. A. Vergara X. Cheng 2002 J. Biol. Chem. 277 26581 26586 12000763 1:CAS:528:DC%2BD38XlsFKqsrg%3D 10.1074/jbc.M203571200 (Pubitemid 34967156)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.29 , pp. 26581-26586
    • Qiao, J.1    Mei, F.C.2    Popov, V.L.3    Vergara, L.A.4    Cheng, X.5
  • 44
    • 47549108691 scopus 로고    scopus 로고
    • Epac and PKA: A tale of two intracellular cAMP receptors
    • DOI 10.1111/j.1745-7270.2008.00438.x
    • X. Cheng Z. Ji T. Tsalkova F. Mei 2008 Acta Biochim. Biophys. Sin. 40 651 662 18604457 1:CAS:528:DC%2BD1cXpvF2qsL0%3D 10.1111/j.1745-7270.2008.00438.x (Pubitemid 352009080)
    • (2008) Acta Biochimica et Biophysica Sinica , vol.40 , Issue.7 , pp. 651-662
    • Cheng, X.1    Ji, Z.2    Tsalkova, T.3    Mei, F.4
  • 47
    • 0344885558 scopus 로고    scopus 로고
    • Structural evidence for feedback activation by Ras·GTP of the Ras-specific nucleotide exchange factor SOS
    • DOI 10.1016/S0092-8674(03)00149-1
    • S. M. Margarit H. Sondermann B. E. Hall B. Nagar A. Hoelz M. Pirruccello D. Bar-Sagi J. Kuriyan 2003 Cell 112 685 695 12628188 1:CAS:528: DC%2BD3sXitFyku78%3D 10.1016/S0092-8674(03)00149-1 (Pubitemid 36331780)
    • (2003) Cell , vol.112 , Issue.5 , pp. 685-695
    • Margarit, S.M.1    Sondermann, H.2    Hall, B.E.3    Nagar, B.4    Hoelz, A.5    Pirruccello, M.6    Bar-Sagi, D.7    Kuriyan, J.8
  • 48
    • 33845999953 scopus 로고    scopus 로고
    • Dissecting the mechanism of Epac activation via hydrogen-deuterium exchange FT-IR and structural modeling
    • DOI 10.1021/bi061701x
    • S. Yu F. Fan S. C. Flores F. Mei X. Cheng 2006 Biochemistry 45 15318 15326 17176054 1:CAS:528:DC%2BD28Xht1KqsL%2FL 10.1021/bi061701x (Pubitemid 46043108)
    • (2006) Biochemistry , vol.45 , Issue.51 , pp. 15318-15326
    • Yu, S.1    Fan, F.2    Flores, S.C.3    Mei, F.4    Cheng, X.5
  • 51
    • 10044253425 scopus 로고    scopus 로고
    • AKAP signalling complexes: Focal points in space and time
    • DOI 10.1038/nrm1527
    • W. Wong J. D. Scott 2004 Nat. Rev. Mol. Cell. Biol. 5 959 970 15573134 1:CAS:528:DC%2BD2cXhtVarsbzJ 10.1038/nrm1527 (Pubitemid 39611533)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.12 , pp. 959-970
    • Wong, W.1    Scott, J.D.2
  • 52
    • 22744445886 scopus 로고    scopus 로고
    • Signaling interplay in ras superfamily function
    • DOI 10.1016/j.cub.2005.07.010, PII S0960982205007487
    • N. Mitin K. L. Rossman C. J. Der 2005 Curr. Biol. 15 R563 R574 16051167 1:CAS:528:DC%2BD2MXmvVKgsb0%3D 10.1016/j.cub.2005.07.010 (Pubitemid 41026614)
    • (2005) Current Biology , vol.15 , Issue.14
    • Mitin, N.1    Rossman, K.L.2    Der, C.J.3
  • 53
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: Critical Elements in the Control of Small G Proteins
    • DOI 10.1016/j.cell.2007.05.018, PII S0092867407006551
    • J. L. Bos H. Rehmann A. Wittinghofer 2007 Cell 129 865 877 17540168 1:CAS:528:DC%2BD2sXmsl2qsLw%3D 10.1016/j.cell.2007.05.018 (Pubitemid 46802708)
    • (2007) Cell , vol.129 , Issue.5 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 55
    • 33746076698 scopus 로고    scopus 로고
    • Role of the exchange protein directly activated by cyclic adenosine 5′-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells
    • DOI 10.1210/en.2006-0056
    • S. Lotfi Z. Li J. Sun Y. Zuo P. P. Lam Y. Kang M. Rahimi D. Islam P. Wang H. Y. Gaisano T. Jin 2006 Endocrinology 147 3727 3736 16644915 1:CAS:528:DC%2BD28XnsVWmsr8%3D 10.1210/en.2006-0056 (Pubitemid 44079377)
    • (2006) Endocrinology , vol.147 , Issue.8 , pp. 3727-3736
    • Lotfi, S.1    Li, Z.2    Sun, J.3    Zuo, Y.4    Lam, P.P.L.5    Kang, Y.6    Rahimi, M.7    Islam, D.8    Wang, P.9    Gaisano, H.Y.10    Jin, T.11
  • 56
    • 27644580732 scopus 로고    scopus 로고
    • Interplay between exchange protein directly activated by cAMP (Epac) and microtubule cytoskeleton
    • DOI 10.1039/b511267b
    • F. C. Mei X. D. Cheng 2005 Mol. Biosyst. 1 325 331 16880999 1:CAS:528:DC%2BD2MXht1Shs77M 10.1039/b511267b (Pubitemid 41579325)
    • (2005) Molecular BioSystems , vol.1 , Issue.4 , pp. 325-331
    • Mei, F.C.1    Cheng, X.2
  • 57
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • DOI 10.1146/annurev.cellbio.21.020604.150721
    • A. B. Jaffe A. Hall 2005 Annu. Rev. Cell. Dev. Biol. 21 247 269 16212495 1:CAS:528:DC%2BD2MXhtlektbrI 10.1146/annurev.cellbio.21.020604.150721 (Pubitemid 41740635)
    • (2005) Annual Review of Cell and Developmental Biology , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 58
    • 14844320785 scopus 로고    scopus 로고
    • MAP1A light chain 2 interacts with exchange protein activated by cyclic AMP 1 (EPAC1) to enhance Rap1 GTPase activity and cell adhesion
    • DOI 10.1074/jbc.M413697200
    • M. Gupta S. J. Yarwood 2005 J. Biol. Chem. 280 8109 8116 15591041 1:CAS:528:DC%2BD2MXhs1yitbc%3D 10.1074/jbc.M413697200 (Pubitemid 40349710)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.9 , pp. 8109-8116
    • Gupta, M.1    Yarwood, S.J.2
  • 63
    • 33751315308 scopus 로고    scopus 로고
    • Phospholipase C epsilon: linking second messengers and small GTPases
    • DOI 10.1016/j.tcb.2006.10.007, PII S0962892406002947
    • T. D. Bunney M. Katan 2006 Trends Cell Biol. 16 640 648 17085049 1:CAS:528:DC%2BD28Xht1OhtLjF 10.1016/j.tcb.2006.10.007 (Pubitemid 44809889)
    • (2006) Trends in Cell Biology , vol.16 , Issue.12 , pp. 640-648
    • Bunney, T.D.1    Katan, M.2
  • 64
    • 0035865293 scopus 로고    scopus 로고
    • Phospholipase Cε: A novel Ras effector
    • DOI 10.1093/emboj/20.4.743
    • G. G. Kelley S. E. Reks J. M. Ondrako A. V. Smrcka 2001 EMBO J. 20 743 754 11179219 1:CAS:528:DC%2BD3MXhsVyht7k%3D 10.1093/emboj/20.4.743 (Pubitemid 32167639)
    • (2001) EMBO Journal , vol.20 , Issue.4 , pp. 743-754
    • Kelley, G.G.1    Reks, S.E.2    Ondrako, J.M.3    Smrcka, A.V.4
  • 67
    • 0036360199 scopus 로고    scopus 로고
    • 11987824 1:CAS:528:DC%2BD38XivFyisbY%3D 10.1007/BFb0116585
    • J. H. Exton 2002 Rev. Physiol. Biochem. Pharmacol. 144 1 94 11987824 1:CAS:528:DC%2BD38XivFyisbY%3D 10.1007/BFb0116585
    • (2002) Rev. Physiol. Biochem. Pharmacol. , vol.144 , pp. 1-94
    • Exton, J.H.1
  • 68
    • 15044363028 scopus 로고    scopus 로고
    • Recent advances in the protein kinase B signaling pathway
    • DOI 10.1016/j.ceb.2005.02.010, Cell Regulation
    • J. R. Woodgett 2005 Curr. Opin. Cell. Biol. 17 150 157 15780591 1:CAS:528:DC%2BD2MXisVCqtb8%3D 10.1016/j.ceb.2005.02.010 (Pubitemid 40380938)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.2 , pp. 150-157
    • Woodgett, J.R.1
  • 70
    • 33644688682 scopus 로고    scopus 로고
    • Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: Effects of silencing CREB gene expression on Akt activation
    • DOI 10.1074/jbc.M507332200
    • U. K. Misra S. V. Pizzo 2005 J. Biol. Chem. 280 38276 38289 16172130 1:CAS:528:DC%2BD2MXht1SktL%2FK 10.1074/jbc.M507332200 (Pubitemid 43853725)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.46 , pp. 38276-38289
    • Misra, U.K.1    Pizzo, S.V.2
  • 71
    • 24344439701 scopus 로고    scopus 로고
    • Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: Implications for cross talk between insulin and adrenaline
    • DOI 10.1016/j.cellsig.2005.03.011, PII S0898656805000641
    • E. O. Brennesvik C. Ktori J. Ruzzin E. Jebens P. R. Shepherd J. Jensen 2005 Cell Signal. 17 1551 1559 15908181 1:CAS:528:DC%2BD2MXpvV2lsbY%3D 10.1016/j.cellsig.2005.03.011 (Pubitemid 41253994)
    • (2005) Cellular Signalling , vol.17 , Issue.12 , pp. 1551-1559
    • Brennesvik, E.O.1    Ktori, C.2    Ruzzin, J.3    Jebens, E.4    Shepherd, P.R.5    Jensen, J.6
  • 74
    • 14944377651 scopus 로고    scopus 로고
    • Regulation of vascular endothelial barrier function by Epac, a cAMP-activated exchange factor for Rap GTPase
    • DOI 10.1182/blood-2004-05-1987
    • X. Cullere S. K. Shaw L. Andersson J. Hirahashi F. W. Luscinskas T. N. Mayads 2005 Blood 105 1950 1955 15374886 1:CAS:528:DC%2BD2MXitVOnsL8%3D 10.1182/blood-2004-05-1987 (Pubitemid 40731777)
    • (2005) Blood , vol.105 , Issue.5 , pp. 1950-1955
    • Cullere, X.1    Shaw, S.K.2    Andersson, L.3    Hirahashi, J.4    Luscinskas, F.W.5    Mayadas, T.N.6
  • 75
    • 24144444059 scopus 로고    scopus 로고
    • Epac1 regulates integrity of endothelial cell junctions through VE-cadherin
    • DOI 10.1016/j.febslet.2005.07.080, PII S001457930500949X
    • M. R. Kooistra M. Corada E. Dejana J. L. Bos 2005 FEBS Lett. 579 4966 4972 16115630 1:CAS:528:DC%2BD2MXpvV2rurk%3D 10.1016/j.febslet.2005.07.080 (Pubitemid 41242837)
    • (2005) FEBS Letters , vol.579 , Issue.22 , pp. 4966-4972
    • Kooistra, M.R.H.1    Corada, M.2    Dejana, E.3    Bos, J.L.4
  • 76
    • 1542365269 scopus 로고    scopus 로고
    • CAMP Dose-dependently Prevents Palmitate-induced Apoptosis by Both Protein Kinase A- and cAMP-Guanine Nucleotide Exchange Factor-dependent Pathwwys in β-Cells
    • DOI 10.1074/jbc.M310330200
    • G. Kwon K. L. Pappan C. A. Marshall J. E. Schaffer M. L. McDaniel 2004 J. Biol. Chem. 279 8938 8945 14688288 1:CAS:528:DC%2BD2cXhs1Onurk%3D 10.1074/jbc.M310330200 (Pubitemid 38295955)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.10 , pp. 8938-8945
    • Kwon, G.1    Pappan, K.L.2    Marshall, C.A.3    Schaffer, J.E.4    McDaniel, M.L.5
  • 78
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • DOI 10.1016/0092-8674(94)90337-9
    • T. A. Springer 1994 Cell 76 301 314 7507411 1:CAS:528:DyaK2cXhs1Srtrg%3D 10.1016/0092-8674(94)90337-9 (Pubitemid 24046692)
    • (1994) Cell , vol.76 , Issue.2 , pp. 301-314
    • Springer, T.A.1
  • 85
    • 41949123680 scopus 로고    scopus 로고
    • 18032709 1:CAS:528:DC%2BD1cXivFaktL0%3D 10.1182/blood-2007-04-086231
    • G. Carmona E. Chavakis U. Koehl A. M. Zeiher S. Dimmeler 2008 Blood 111 2640 2646 18032709 1:CAS:528:DC%2BD1cXivFaktL0%3D 10.1182/blood-2007-04-086231
    • (2008) Blood , vol.111 , pp. 2640-2646
    • Carmona, G.1    Chavakis, E.2    Koehl, U.3    Zeiher, A.M.4    Dimmeler, S.5
  • 87
    • 0029946652 scopus 로고    scopus 로고
    • Regulation of leukocyte integrin function: Affinity vs. avidity
    • DOI 10.1002/(SICI)1097-4644(19960616)61:4<554::AID-JCB8>3.0.CO;2-N
    • M. Stewart N. Hogg 1996 J. Cell. Biochem. 61 554 561 8806078 1:CAS:528:DyaK28Xkt1Wqu7o%3D 10.1002/(SICI)1097-4644(19960616)61:4<554::AID- JCB8>3.0.CO;2-N (Pubitemid 26240132)
    • (1996) Journal of Cellular Biochemistry , vol.61 , Issue.4 , pp. 554-561
    • Stewart, M.1    Hogg, N.2
  • 88
    • 0036220127 scopus 로고    scopus 로고
    • Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation
    • DOI 10.1038/nsb779
    • N. Beglova S. C. Blacklow J. Takagi T. A. Springer 2002 Nat. Struct. Biol. 9 282 287 11896403 1:CAS:528:DC%2BD38Xis1Kitr4%3D 10.1038/nsb779 (Pubitemid 34289901)
    • (2002) Nature Structural Biology , vol.9 , Issue.4 , pp. 282-287
    • Beglova, N.1    Blacklow, S.C.2    Takagi, J.3    Springer, T.A.4
  • 89
    • 0034004457 scopus 로고    scopus 로고
    • Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase
    • DOI 10.1128/MCB.20.6.1956-1969.2000
    • K. Katagiri M. Hattori N. Minato S. Irie K. Takatsu T. Kinashi 2000 Mol. Cell. Biol. 20 1956 1969 10688643 1:CAS:528:DC%2BD3cXhsVKmsLo%3D 10.1128/MCB.20.6.1956-1969.2000 (Pubitemid 30123812)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.6 , pp. 1956-1969
    • Katagiri, K.1    Hattori, M.2    Minato, N.3    Irie, S.-K.4    Takatsu, K.5    Kinashi, T.6
  • 91
    • 33846596607 scopus 로고    scopus 로고
    • Interactome of transforming growth factor-β type I receptor (TβRI): Inhibition of TGFβ signaling by Epac1
    • DOI 10.1021/pr060427q
    • P. Conrotto I. Yakymovych M. Yakymovych S. Souchelnytskyi 2007 J. Proteome. Res. 6 287 297 17203972 1:CAS:528:DC%2BD28XhtlWmu7vP 10.1021/pr060427q (Pubitemid 46173680)
    • (2007) Journal of Proteome Research , vol.6 , Issue.1 , pp. 287-297
    • Conrotto, P.1    Yakymovych, I.2    Yakymovych, M.3    Souchelnytskyi, S.4
  • 93
    • 0035067974 scopus 로고    scopus 로고
    • Evaluation of signal transduction pathways in chemoattractant-induced human monocyte chemotaxis
    • DOI 10.1023/A:1007152903135
    • J. S. Fine H. D. Byrnes P. J. Zavodny R. W. Hipkin 2001 Inflammation 25 61 67 11321360 1:CAS:528:DC%2BD3MXjtFyht7w%3D 10.1023/A:1007152903135 (Pubitemid 32295740)
    • (2001) Inflammation , vol.25 , Issue.2 , pp. 61-67
    • Fine, J.S.1    Byrnes, H.D.2    Zavodny, P.J.3    Hipkin, R.W.4
  • 94
    • 33645635391 scopus 로고    scopus 로고
    • Relaxin stimulates leukocyte adhesion and migration through a relaxin receptor LGR7-dependent mechanism
    • DOI 10.1074/jbc.M506665200
    • K. A. Figueiredo A. L. Mui C. C. Nelson M. E. Cox 2006 J. Biol. Chem. 281 3030 3039 16303766 1:CAS:528:DC%2BD28XhtFSnurw%3D 10.1074/jbc.M506665200 (Pubitemid 43845912)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.6 , pp. 3030-3039
    • Figueiredo, K.A.1    Mui, A.L.2    Nelson, C.C.3    Cox, M.E.4
  • 95
    • 0029616709 scopus 로고
    • Urokinase-type plasminogen activator-induced monocyte adhesion requires a carboxyl-terminal lysine and cAMP-dependent signal transduction
    • DOI 10.1074/jbc.270.51.30282
    • C. Li J. N. Liu V. Gurewich 1995 J. Biol. Chem. 270 30282 30285 8530448 1:CAS:528:DyaK28XhtFKisg%3D%3D 10.1074/jbc.270.51.30282 (Pubitemid 26005076)
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.51 , pp. 30282-30285
    • Li, C.1    Liu, J.-N.2    Gurewich, V.3
  • 96
    • 15044353649 scopus 로고    scopus 로고
    • Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes
    • DOI 10.1016/j.ceb.2005.01.003, Cell Regulation
    • G. S. Baillie M. D. Houslay 2005 Curr. Opin. Cell Biol. 17 129 134 15780588 1:CAS:528:DC%2BD2MXisVCqtLY%3D 10.1016/j.ceb.2005.01.003 (Pubitemid 40380935)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.2 , pp. 129-134
    • Baillie, G.S.1    Houslay, M.D.2
  • 97
    • 0038561221 scopus 로고    scopus 로고
    • Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
    • DOI 10.1083/jcb.200301133
    • M. Shimonaka K. Katagiri T. Nakayama N. Fujita T. Tsuruo O. Yoshie T. Kinashi 2003 J. Cell. Biol. 161 417 427 12707305 1:CAS:528:DC%2BD3sXjtl2itrw%3D 10.1083/jcb.200301133 (Pubitemid 36529858)
    • (2003) Journal of Cell Biology , vol.161 , Issue.2 , pp. 417-427
    • Shimonaka, M.1    Katagiri, K.2    Nakayama, T.3    Fujita, N.4    Tsuruo, T.5    Yoshie, O.6    Kinashi, T.7
  • 99
    • 0042490495 scopus 로고    scopus 로고
    • RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1
    • DOI 10.1038/ni950
    • K. Katagiri A. Maeda M. Shimonaka T. Kinashi 2003 Nat. Immunol. 4 741 748 12845325 1:CAS:528:DC%2BD3sXlvVajtbY%3D 10.1038/ni950 (Pubitemid 36986757)
    • (2003) Nature Immunology , vol.4 , Issue.8 , pp. 741-748
    • Katagiri, K.1    Maeda, A.2    Shimonaka, M.3    Kinashi, T.4
  • 100
    • 2342597085 scopus 로고    scopus 로고
    • Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL
    • DOI 10.1016/j.imlet.2004.02.008, PII S0165247804000409
    • T. Kinashi K. Katagiri 2004 Immunol. Lett. 93 1 5 15134891 1:CAS:528:DC%2BD2cXjvVeqs7c%3D 10.1016/j.imlet.2004.02.008 (Pubitemid 38591512)
    • (2004) Immunology Letters , vol.93 , Issue.1 , pp. 1-5
    • Kinashi, T.1    Katagiri, K.2
  • 104
    • 0034635221 scopus 로고    scopus 로고
    • Roles of PLC-β2 and -β3 and PI3kγ in chemoattractant- mediated signal transduction
    • DOI 10.1126/science.287.5455.1046
    • Z. Li H. Jiang W. Xie Z. Zhang A. V. Smrcka D. Wu 2000 Science 287 1046 1049 10669417 1:CAS:528:DC%2BD3cXhtFyqtbw%3D 10.1126/science.287.5455.1046 (Pubitemid 30094361)
    • (2000) Science , vol.287 , Issue.5455 , pp. 1046-1049
    • Li, Z.1    Jiang, H.2    Xie, W.3    Zhang, Z.4    Smrcka, A.V.5    Wu, D.6
  • 105
    • 0041327718 scopus 로고    scopus 로고
    • 10.1242/jcs.00703 1:CAS:528:DC%2BD3sXntFyjt7Y%3D
    • S. Merlot R. A. Firtel 2000 J. Cell Sci. 116 3471 3478 10.1242/jcs.00703 1:CAS:528:DC%2BD3sXntFyjt7Y%3D
    • (2000) J. Cell Sci. , vol.116 , pp. 3471-3478
    • Merlot, S.1    Firtel, R.A.2
  • 106
    • 36249032544 scopus 로고    scopus 로고
    • The macrophage: Past, present and future
    • DOI 10.1002/eji.200737638
    • S. Gordon 2007 Eur. J. Immunol. 37 S9 S17 17972350 1:CAS:528: DC%2BD2sXhsVSgtbbJ 10.1002/eji.200737638 (Pubitemid 350131264)
    • (2007) European Journal of Immunology , vol.37 , Issue.SUPPL. 1
    • Gordon, S.1
  • 109
    • 33748163485 scopus 로고    scopus 로고
    • 2
    • DOI 10.1182/blood-2006-05-021881
    • Z. Hazan-Eitan Y. Weinstein N. Hadad A. Konforty R. Levy 2006 Blood 108 1758 1766 16709925 1:CAS:528:DC%2BD28Xpt1Slurc%3D 10.1182/blood-2006-05-021881 (Pubitemid 44316147)
    • (2006) Blood , vol.108 , Issue.5 , pp. 1758-1766
    • Hazan-Eitan, Z.1    Weinstein, Y.2    Hadad, N.3    Konforty, A.4    Levy, R.5
  • 111
    • 0034710567 scopus 로고    scopus 로고
    • 10985384 1:CAS:528:DC%2BD3cXmtVGiuro%3D 10.1016/S0960-9822(00)00641-2
    • E. Caron A. J. Self A. Hall 2000 Curr. Biol. 10 974 978 10985384 1:CAS:528:DC%2BD3cXmtVGiuro%3D 10.1016/S0960-9822(00)00641-2
    • (2000) Curr. Biol. , vol.10 , pp. 974-978
    • Caron, E.1    Self, A.J.2    Hall, A.3
  • 112
    • 4344588424 scopus 로고    scopus 로고
    • CAMP protects neutrophils against TNF-α-induced apoptosis by activation of cAMP-dependent protein kinase, independently of exchange protein directly activated by cAMP (Epac)
    • DOI 10.1189/jlb.0104005
    • C. Krakstad A. E. Christensen S. O. Doskeland 2004 J. Leukocyte Biol. 76 641 647 15178699 1:CAS:528:DC%2BD2cXnsVaksL0%3D 10.1189/jlb.0104005 (Pubitemid 39129097)
    • (2004) Journal of Leukocyte Biology , vol.76 , Issue.3 , pp. 641-647
    • Krakstad, C.1    Christensen, A.E.2    Doskeland, S.O.3
  • 113
    • 0030176170 scopus 로고    scopus 로고
    • Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: A possible pathway for inhibition of the respiratory burst
    • DOI 10.1016/0898-6568(96)00052-6
    • C. Bengis-Garber N. Gruener 1996 Cell Signal. 8 291 296 8842530 1:CAS:528:DyaK28XkvFKhs7g%3D 10.1016/0898-6568(96)00052-6 (Pubitemid 26245256)
    • (1996) Cellular Signalling , vol.8 , Issue.4 , pp. 291-296
    • Bengis-Garber, C.1    Gruener, N.2
  • 114
    • 34848843529 scopus 로고    scopus 로고
    • Malaria circumsporozoite protein inhibits the respiratory burst in Kupffer cells
    • DOI 10.1111/j.1462-5822.2007.00982.x
    • I. Usynin C. Klotz U. Frevert 2007 Cell Microbiol. 9 2610 2628 17573905 1:CAS:528:DC%2BD2sXht1aisrrK 10.1111/j.1462-5822.2007.00982.x (Pubitemid 47500514)
    • (2007) Cellular Microbiology , vol.9 , Issue.11 , pp. 2610-2628
    • Usynin, I.1    Klotz, C.2    Frevert, U.3
  • 115
  • 116
    • 36749040280 scopus 로고    scopus 로고
    • 2 on the subcellular localization of Epac-1 and Rap1 proteins during Fcγ-receptor-mediated phagocytosis in alveolar macrophages
    • DOI 10.1016/j.yexcr.2007.10.011, PII S0014482707004910
    • T. G. Brock C. H. Serezani J. K. Carstens M. Peters-Golden D. M. Aronoff 2008 Exp. Cell. Res. 314 255 263 18021770 1:CAS:528:DC%2BD2sXhsVWjtLnL 10.1016/j.yexcr.2007.10.011 (Pubitemid 350216104)
    • (2008) Experimental Cell Research , vol.314 , Issue.2 , pp. 255-263
    • Brock, T.G.1    Serezani, C.H.2    Carstens, J.K.3    Peters-Golden, M.4    Aronoff, D.M.5
  • 119
    • 0025286210 scopus 로고
    • Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
    • DOI 10.1038/346574a0
    • C. V. Harding E. R. Unanue 1990 Nature 346 574 576 2115981 1:CAS:528:DyaK3cXltFens7c%3D 10.1038/346574a0 (Pubitemid 20238811)
    • (1990) Nature , vol.346 , Issue.6284 , pp. 574-576
    • Harding, C.V.1    Unanue, E.R.2
  • 121
    • 0023908650 scopus 로고
    • 3259335 1:CAS:528:DyaL1cXktlKntro%3D 10.1126/science.3259335
    • M. A. Goldsmith A. Weiss 1988 Science 240 1029 1031 3259335 1:CAS:528:DyaL1cXktlKntro%3D 10.1126/science.3259335
    • (1988) Science , vol.240 , pp. 1029-1031
    • Goldsmith, M.A.1    Weiss, A.2
  • 122
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • DOI 10.1038/25764
    • C. R. F. Monks B. A. Freiberg H. Kupfer N. Sciaky A. Kupfer 1998 Nature 395 82 86 9738502 1:CAS:528:DyaK1cXmtVSlt7c%3D 10.1038/25764 (Pubitemid 28420234)
    • (1998) Nature , vol.395 , Issue.6697 , pp. 82-86
    • Monks, C.R.F.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 124
    • 0033614036 scopus 로고    scopus 로고
    • Costimulation: Building an immunological synapse
    • DOI 10.1126/science.283.5402.649
    • M. L. Dustin A. S. Shaw 1999 Science 29 649 650 10.1126/science.283.5402. 649 (Pubitemid 29074994)
    • (1999) Science , vol.283 , Issue.5402 , pp. 649-650
    • Dustin, M.L.1    Shaw, A.S.2
  • 125
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • DOI 10.1126/science.285.5425.221
    • A. Grakoui S. Bromley C. Sumen M. Davis A. Shaw P. Allen M. Dustin 1999 Science 285 221 227 10398592 1:CAS:528:DyaK1MXks1SjsLg%3D 10.1126/science.285. 5425.221 (Pubitemid 29329988)
    • (1999) Science , vol.285 , Issue.5425 , pp. 221-227
    • Grakoui, A.1    Bromley, S.K.2    Sumen, C.3    Davis, M.M.4    Shaw, A.S.5    Allen, P.M.6    Dustin, M.L.7
  • 127
    • 0033534678 scopus 로고    scopus 로고
    • From TCR engagement to T cell activation: A kinetic view of T cell behavior
    • DOI 10.1016/S0092-8674(00)80952-6
    • A. Lanzavecchia G. Lezzi A. Viola 1999 Cell 96 1 4 9989490 1:CAS:528:DyaK1MXmslahtQ%3D%3D 10.1016/S0092-8674(00)80952-6 (Pubitemid 29044146)
    • (1999) Cell , vol.96 , Issue.1 , pp. 1-4
    • Lanzavecchia, A.1    Iezzi, G.2    Viola, A.3
  • 128
    • 0024443411 scopus 로고
    • T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1
    • DOI 10.1038/341619a0
    • M. L. Dustin T. A. Springer 1989 Nature 341 619 624 2477710 1:CAS:528:DyaL1MXmtlShtbg%3D 10.1038/341619a0 (Pubitemid 19257309)
    • (1989) Nature , vol.341 , Issue.6243 , pp. 619-624
    • Dustin, M.L.1    Springer, T.A.2
  • 129
    • 0034232037 scopus 로고    scopus 로고
    • 10881170 1:CAS:528:DC%2BD3cXls1yqsrY%3D 10.1038/76877
    • M. L. Dustin J. A. Cooper 2000 Nat. Immunol. 1 23 29 10881170 1:CAS:528:DC%2BD3cXls1yqsrY%3D 10.1038/76877
    • (2000) Nat. Immunol. , vol.1 , pp. 23-29
    • Dustin, M.L.1    Cooper, J.A.2
  • 131
    • 0036146452 scopus 로고    scopus 로고
    • Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses
    • DOI 10.1128/MCB.22.4.1001-1015.2002
    • K. Katagiri M. Hattori N. Minato T. Kinashi 2002 Mol. Cell. Biol. 22 1001 1015 11809793 1:CAS:528:DC%2BD38XovVWkuw%3D%3D 10.1128/MCB.22.4.1001-1015.2002 (Pubitemid 34094838)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.4 , pp. 1001-1015
    • Katagiri, K.1    Hattori, M.2    Minato, N.3    Kinashi, T.4
  • 132
    • 34447301486 scopus 로고    scopus 로고
    • Small GTPases and LFA-1 reciprocally modulate adhesion and signaling
    • DOI 10.1111/j.1600-065X.2007.00538.x
    • A. Mor M. L. Dustin M. R. Philips 2007 Immunol. Rev. 218 114 125 17624948 1:CAS:528:DC%2BD2sXhtVSiu7zM 10.1111/j.1600-065X.2007.00538.x (Pubitemid 47052308)
    • (2007) Immunological Reviews , vol.218 , Issue.1 , pp. 114-125
    • Mor, A.1    Dustin, M.L.2    Philips, M.R.3
  • 133
    • 0023077608 scopus 로고
    • 1:CAS:528:DyaL2sXhvFCiu7g%3D 10.1146/annurev.iy.05.040187.003201
    • M. Plaut 1987 Ann. Rev. Immunol. 5 621 669 1:CAS:528:DyaL2sXhvFCiu7g%3D 10.1146/annurev.iy.05.040187.003201
    • (1987) Ann. Rev. Immunol. , vol.5 , pp. 621-669
    • Plaut, M.1
  • 135
    • 0030871055 scopus 로고    scopus 로고
    • Essential lymphocyte function associated 1 (LFA-1): Intercellular adhesion molecule interactions for T cell-mediated B cell apoptosis by Fas/APO-1/CD95
    • DOI 10.1084/jem.186.7.1171
    • J. Wang M. J. Lenardo 1997 J. Exp. Med. 186 1171 1176 9314566 1:CAS:528:DyaK2sXmsFaqs7o%3D 10.1084/jem.186.7.1171 (Pubitemid 27441161)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.7 , pp. 1171-1176
    • Wang, J.1    Lenardo, M.J.2
  • 136
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27(Kip1) is instigated by Jab1
    • DOI 10.1038/18230
    • K. Tomoda Y. Kubota J. Kato 1999 Nature 398 160 165 10086358 1:CAS:528:DyaK1MXhvFKisLc%3D 10.1038/18230 (Pubitemid 29135455)
    • (1999) Nature , vol.398 , Issue.6723 , pp. 160-165
    • Tomoda, K.1    Kubota, Y.2    Kato, J.-Y.3
  • 137
    • 0033621780 scopus 로고    scopus 로고
    • P27(kip1) functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
    • DOI 10.1038/73144
    • V. A. Boussiotis G. J. Freeman P. A. Taylor A. Berezovskaya I. Grass B. R. Blazar L. M. Nadler 2000 Nat. Med. 6 290 297 10700231 1:CAS:528: DC%2BD3cXhslygsrc%3D 10.1038/73144 (Pubitemid 30148621)
    • (2000) Nature Medicine , vol.6 , Issue.3 , pp. 290-297
    • Boussiotis, V.A.1    Freeman, G.J.2    Taylor, P.A.3    Berezovskaya, A.4    Grass, I.5    Blazar, B.R.6    Nadler, L.M.7
  • 138
    • 18044405159 scopus 로고    scopus 로고
    • Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4
    • DOI 10.1128/MCB.25.10.4117-4128.2005
    • T. J. Dillon K. D. Carey S. A. Wetzel D. C. Parker P. J. Stork 2005 Mol. Cell Biol. 25 4117 4128 15870282 1:CAS:528:DC%2BD2MXktlSmu7g%3D 10.1128/MCB.25.10.4117-4128.2005 (Pubitemid 40617658)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.10 , pp. 4117-4128
    • Dillon, T.J.1    Carey, K.D.2    Wetzel, S.A.3    Parker, D.C.4    Stork, P.J.S.5
  • 139
    • 0030707866 scopus 로고    scopus 로고
    • 2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor ζ and ZAP70
    • DOI 10.1084/jem.186.10.1645
    • C. R. Calvo D. Amsen A. M. Kruisbeek 1997 J. Exp. Med. 186 1645 1653 9362525 1:CAS:528:DyaK2sXnsVeisbY%3D 10.1084/jem.186.10.1645 (Pubitemid 27506278)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.10 , pp. 1645-1653
    • Calvo, C.R.1    Amsen, D.2    Kruisbeek, A.M.3
  • 140
    • 0030812812 scopus 로고    scopus 로고
    • Maintenance of human T cell anergy: Blocking of IL-2 gene transcription by activated Rap1
    • DOI 10.1126/science.278.5335.124
    • V. A. Boussiotis G. J. Freeman A. Berezovskaya D. L. Barber L. M. Nadler 1997 Science 278 124 128 9311917 1:CAS:528:DyaK2sXmsV2lsr8%3D 10.1126/science.278.5335.124 (Pubitemid 27446291)
    • (1997) Science , vol.278 , Issue.5335 , pp. 124-128
    • Boussiotis, V.A.1    Freeman, G.J.2    Berezovskaya, A.3    Barber, D.L.4    Nadler, L.M.5
  • 142
    • 0035056017 scopus 로고    scopus 로고
    • CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
    • DOI 10.1146/annurev.immunol.19.1.565
    • C. A. Chambers M. S. Kuhns J. G. Egen J. P. Allison 2001 Annu. Rev. Immunol. 19 565 594 11244047 1:CAS:528:DC%2BD3MXivFKgurc%3D 10.1146/annurev. immunol.19.1.565 (Pubitemid 32368046)
    • (2001) Annual Review of Immunology , vol.19 , pp. 565-594
    • Chambers, C.A.1    Kuhns, M.S.2    Egen, J.G.3    Allison, J.P.4
  • 144
    • 0038136924 scopus 로고    scopus 로고
    • Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells
    • DOI 10.1074/jbc.M204652200
    • T. Bouschet V. Perez C. Fernandez J. Bockaert A. Eychene L. Journot 2003 J. Biol. Chem. 278 4778 4785 12473665 1:CAS:528:DC%2BD3sXhtVKls7g%3D 10.1074/jbc.M204652200 (Pubitemid 36800980)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.7 , pp. 4778-4785
    • Bouschet, T.1    Perez, V.2    Fernandez, C.3    Bockaert, J.4    Eychene, A.5    Journot, L.6
  • 146
    • 0034724873 scopus 로고    scopus 로고
    • The association of CRKII with C3G can be regulated by integrins and defines a novel means to regulate the mitogen-activated protein kinases
    • DOI 10.1074/jbc.275.17.13118
    • C. S. Buensuceso T. E. O'Toole 2000 J. Biol. Chem. 275 13118 13125 10777617 1:CAS:528:DC%2BD3cXjtVaqsLw%3D 10.1074/jbc.275.17.13118 (Pubitemid 30241474)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.17 , pp. 13118-13125
    • Buensuceso, C.S.1    O'Toole, T.E.2
  • 148
    • 0242521711 scopus 로고    scopus 로고
    • Changes in bad phosphorylation are correlated with BCR-induced apoptosis of WEHI-231 immature B cells
    • DOI 10.1016/S0300-9084(03)00140-8
    • E. Malissein M. I. Verdier M. H. Ratinaud D. Troutaud 2003 Biochimie 85 733 740 14585539 1:CAS:528:DC%2BD3sXosVymsLk%3D 10.1016/S0300-9084(03)00140-8 (Pubitemid 37383791)
    • (2003) Biochimie , vol.85 , Issue.8 , pp. 733-740
    • Malissein, E.1    Verdier, M.2    Ratinaud, M.H.3    Troutaud, D.4
  • 149
  • 151
    • 33644765206 scopus 로고    scopus 로고
    • Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation
    • DOI 10.1128/MCB.26.6.2130-2145.2006
    • Z. Wang T. J. Dillon V. Pokala S. Mishra K. Labudda B. Hunter P. J. Stork 2006 Mol. Cell. Biol. 26 2130 2145 16507992 1:CAS:528:DC%2BD28XislygtL0%3D 10.1128/MCB.26.6.2130-2145.2006 (Pubitemid 43346916)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.6 , pp. 2130-2145
    • Wang, Z.1    Dillon, T.J.2    Pokala, V.3    Mishra, S.4    Labudda, K.5    Hunter, B.6    Stork, P.J.S.7
  • 153
    • 0036884819 scopus 로고    scopus 로고
    • Regulation of B-cell fate by antigen-receptor signals
    • DOI 10.1038/nri955
    • H. Niiro E. A. Clark 2002 Nat. Rev. Immunol. 2 945 956 12461567 1:CAS:528:DC%2BD38XptFKnu7k%3D 10.1038/nri955 (Pubitemid 37323215)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.12 , pp. 945-956
    • Niiro, H.1    Clark, E.A.2
  • 154
    • 0028959263 scopus 로고
    • 7768548 1:STN:280:DyaK2M3os1ajuw%3D%3D 10.1038/icb.1995.2
    • A. R. Gottschalk J. Quintans 1995 Immunol. Cell Biol. 73 8 16 7768548 1:STN:280:DyaK2M3os1ajuw%3D%3D 10.1038/icb.1995.2
    • (1995) Immunol. Cell Biol. , vol.73 , pp. 8-16
    • Gottschalk, A.R.1    Quintans, J.2
  • 155
    • 0025345758 scopus 로고
    • 2342467 1:CAS:528:DyaK3cXksFKqurw%3D
    • D. M. Page A. L. DeFranco 1990 Mol. Cell. Biol. 10 3003 3012 2342467 1:CAS:528:DyaK3cXksFKqurw%3D
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 3003-3012
    • Page, D.M.1    Defranco, A.L.2
  • 160
    • 2442421056 scopus 로고    scopus 로고
    • RasGRP1 Sensitizes an Immature B Cell Line to Antigen Receptor-induced Apoptosis
    • DOI 10.1074/jbc.M314273200
    • B. Guilbault R. J. Kay 2004 J. Biol. Chem. 279 19523 19530 14970203 1:CAS:528:DC%2BD2cXjs1Wju74%3D 10.1074/jbc.M314273200 (Pubitemid 38623387)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.19 , pp. 19523-19530
    • Guilbault, B.1    Kay, R.J.2
  • 163
    • 0034104590 scopus 로고    scopus 로고
    • The Ras branch of small GTPases: Ras family members don't fall far from the tree
    • DOI 10.1016/S0955-0674(99)00071-X
    • G. W. Reuther C. J. Der 2000 Curr. Opin. Cell Biol. 12 157 165 10712923 1:CAS:528:DC%2BD3cXitVantL0%3D 10.1016/S0955-0674(99)00071-X (Pubitemid 30142561)
    • (2000) Current Opinion in Cell Biology , vol.12 , Issue.2 , pp. 157-165
    • Reuther, G.W.1    Der, C.J.2
  • 164
    • 0035135929 scopus 로고    scopus 로고
    • 11152757 1:CAS:528:DC%2BD3MXitV2ktLw%3D
    • Y. Takai T. Sasaki T. Matozaki 2001 Physiol. Rev. 81 153 208 11152757 1:CAS:528:DC%2BD3MXitV2ktLw%3D
    • (2001) Physiol. Rev. , vol.81 , pp. 153-208
    • Takai, Y.1    Sasaki, T.2    Matozaki, T.3
  • 165
    • 15044359236 scopus 로고    scopus 로고
    • Linking Rap to cell adhesion
    • DOI 10.1016/j.ceb.2005.02.009, Cell Regulation
    • J. L. Bos 2005 Curr. Opin. Cell. Biol. 17 123 128 15780587 1:CAS:528:DC%2BD2MXisVCqtLk%3D 10.1016/j.ceb.2005.02.009 (Pubitemid 40380934)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.2 , pp. 123-128
    • Bos, J.L.1
  • 167
    • 0037162696 scopus 로고    scopus 로고
    • Ras and Rap control AMPA receptor trafficking during synaptic plasticity
    • DOI 10.1016/S0092-8674(02)00897-8
    • J. Zhu Y. Qin M. Zhao L. van Aelst R. Malinow 2002 Cell 110 443 455 12202034 1:CAS:528:DC%2BD38Xmslyjtrc%3D 10.1016/S0092-8674(02)00897-8 (Pubitemid 35232288)
    • (2002) Cell , vol.110 , Issue.4 , pp. 443-455
    • Zhu J.Julius1    Qin, Y.2    Zhao, M.3    Van Aelst, L.4    Malinow, R.5
  • 168
    • 0037329747 scopus 로고    scopus 로고
    • Cellular functions of the Rap1 GTP-binding protein: A pattern emerges
    • DOI 10.1242/jcs.00238
    • E. Caron 2003 J. Cell Sci. 116 435 440 12508104 1:CAS:528: DC%2BD3sXhtlOgsro%3D 10.1242/jcs.00238 (Pubitemid 36231283)
    • (2003) Journal of Cell Science , vol.116 , Issue.3 , pp. 435-440
    • Caron, E.1
  • 169
    • 0034677894 scopus 로고    scopus 로고
    • Divergent roles for Ras and Rap in the activation of p38 mitogen- activated protein kinase by interleukin-1
    • DOI 10.1074/jbc.275.11.7818
    • E. M. Palsson M. Popoff M. Thelestam L. A. O'Neill 2000 J. Biol. Chem. 275 7818 7825 10713096 1:CAS:528:DC%2BD3cXitVylsbs%3D 10.1074/jbc.275.11.7818 (Pubitemid 30159688)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.11 , pp. 7818-7825
    • Palsson, E.M.1    Popoff, M.2    Thelestam, M.3    O'Neill, L.A.J.4
  • 170
    • 0035793468 scopus 로고    scopus 로고
    • CD98 induces LFA-1-mediated cell adhesion in lymphoid cells via activation of Rap1
    • DOI 10.1016/S0014-5793(00)02222-5, PII S0014579300022225
    • K. Suga K. Katagiri T. Kinashi M. Harazaki T. Iizuka M. Hattori N. Minato 2001 FEBS Lett. 489 249 253 11165259 1:CAS:528:DC%2BD3MXpsF2msQ%3D%3D 10.1016/S0014-5793(00)02222-5 (Pubitemid 32126418)
    • (2001) FEBS Letters , vol.489 , Issue.2-3 , pp. 249-253
    • Suga, K.1    Katagiri, K.2    Kinashi, T.3    Harazaki, M.4    Iizuka, T.5    Hattori, M.6    Minato, N.7
  • 172
    • 35548936992 scopus 로고    scopus 로고
    • KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell-cell junctions
    • DOI 10.1083/jcb.200705175
    • A. Glading J. Han R. A. Stockton M. H. Ginsberg 2007 J. Cell Biol. 179 247 254 17954608 1:CAS:528:DC%2BD2sXht1ekurnK 10.1083/jcb.200705175 (Pubitemid 350004889)
    • (2007) Journal of Cell Biology , vol.179 , Issue.2 , pp. 247-254
    • Glading, A.1    Han, J.2    Stockton, R.A.3    Ginsberg, M.H.4
  • 173
    • 5444230311 scopus 로고    scopus 로고
    • Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors
    • DOI 10.1083/jcb.200404068
    • W. T. Arthur L. A. Quilliam J. A. Cooper 2004 J. Cell Biol. 167 111 122 15479739 1:CAS:528:DC%2BD2cXosVOiu7k%3D 10.1083/jcb.200404068 (Pubitemid 39363419)
    • (2004) Journal of Cell Biology , vol.167 , Issue.1 , pp. 111-122
    • Arthur, W.T.1    Quilliam, L.A.2    Cooper, J.A.3

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