cAMP Dose-dependently Prevents Palmitate-induced Apoptosis by Both Protein Kinase A- and cAMP-Guanine Nucleotide Exchange Factor-dependent Pathwwys in β-Cells

Journal of Biological Chemistry

Volumn 279, Issue 10, 2004, Pages 8938-8945

  Kwon, Guim ^a   Pappan, Kirk L ^a   Marshall, Connie A ^a   Schaffer, Jean E ^a   McDaniel, Michael L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CHEMICAL ACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; FATTY ACIDS; PROTEINS;

APOPTOSIS; BIOCHEMICAL PATHWAYS;

BIOCHEMISTRY;

BUCLADESINE; CASPASE 3; CASPASE 3 INHIBITOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; EXENDIN 4; FORSKOLIN; GLUCAGON LIKE PEPTIDE 1; GUANINE NUCLEOTIDE EXCHANGE FACTOR; ISOBUTYLMETHYLXANTHINE; LIPOCORTIN 5; PALMITIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; INSULIN RESISTANCE; LIPID METABOLISM; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; TARGET CELL;

1-METHYL-3-ISOBUTYLXANTHINE; ANIMALS; APOPTOSIS; CARBAZOLES; CELL LINE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INDOLES; ISLETS OF LANGERHANS; ISOQUINOLINES; MICE; PALMITATES; PYRROLES; SIGNAL TRANSDUCTION; SULFONAMIDES;

ANIMALIA;

EID: 1542365269     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310330200     Document Type: Article

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