Prostaglandins PGE2 and PGI2 promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation

Experimental Cell Research

Volumn 313, Issue 11, 2007, Pages 2504-2520

  Birukova, Anna A ^a   Zagranichnaya, Tatiana ^a   Fu, Panfeng ^a   Alekseeva, Elena ^a   Chen, Weiguo ^a   Jacobson, Jeffrey R ^a   Birukov, Konstantin G ^a  

^a W410   (United States)

Author keywords

Cytoskeleton; GEFs; Lung endothelium; Permeability; PKA; Small GTPases

Indexed keywords

ACTIN; ANTIPORTER; BERAPROST; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOSKELETON PROTEIN; DEXTRAN; GUANOSINE TRIPHOSPHATASE; LIPID; PROSTACYCLIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROTEIN EPAC1; PROTEIN TIAM1; PROTEIN VAV2; RAC PROTEIN; RAP1 PROTEIN; SMALL INTERFERING RNA; THROMBIN; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; CELL JUNCTION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOSKELETON; ELECTRIC RESISTANCE; ENDOTHELIUM CELL; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LUNG ENDOTHELIUM; MALE; MECHANICAL STRESS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TIDAL VOLUME; WOUND HEALING;

EID: 34250177621     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2007.03.036     Document Type: Article

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