Changes in bad phosphorylation are correlated with BCR-induced apoptosis of WEHI-231 immature B cells

Biochimie

Volumn 85, Issue 8, 2003, Pages 733-740

  Malissein, E ^a   Verdier, M ^a   Ratinaud, M H ^a   Troutaud, D ^a  

^a CNRS   (France)

Author keywords

Apoptosis; Bad phosphorylation; BCR; Immature B cells; Mitochondria

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M ANTIBODY; LYMPHOCYTE ANTIGEN RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OKADAIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN BAD; PROTEIN BCL 2; PROTEIN KINASE INHIBITOR; SERINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL MATURATION; CONTROLLED STUDY; LYMPHOMA CELL LINE; MITOCHONDRION; NONHUMAN; PROTEIN PHOSPHORYLATION;

MURINAE;

EID: 0242521711     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(03)00140-8     Document Type: Article

References (46)

1. K. Rajewsky, Clonal selection and learning in the antibody system, Nature 381 (1996) 751-758.
2. A.L. DeFranco, The complexity of signaling pathways activated by the BCR, Curr. Opin. Immunol. 9 (1997) 296-308.
3. C.G. Klaus, M.S. Choi, E.W. Lam, C. Johnson-Leger, J. Cliff, CD40: A pivotal receptor in the determination of life/death decisions in B lymphocytes, Int. Rev. Immunol. 15 (1997) 5-31.
4. T. Kurosaki Regulation of B cell fates by BCR signaling components, Curr. Opin. Immunol. 14 (2002) 341-347.
5. G.J.V. Nossal, Negative selection of lymphocytes, Cell 76 (1994) 229-239.
6. D.R. Green, D.W. Scott, Activation-induced apoptosis in lymphocytes, Curr. Opin. Immunol. 6 (1994) 476-487.
7. N.R. Klinman, The "clonal selection hypothesis" and current concepts of B cell tolerance, Immunity 5 (1996) 189-195.
8. L.E. Benhamou, P. Cazenave, P. Sarthou, Anti-immunoglobulins induce death by apoptosis in WEHI-231 B lymphoma cells, Eur. J. Immunol. 20 (1990) 1405-1407.
9. D.W. Scott, Analysis of B cell tolerance in vitro, Adv. Immunol. 54 (1993) 393-425.
10. T. Doi, N. Motoyama, A. Tokunoga, T. Watanabe, Death signals from the B cell antigen receptor target mitochondria, activating necrotic and apoptotic death cascades in a murine B cell line, WEHI-231, Int. Immunol. 11 (1999) 933-941.
11. E. Katz, M.R. Deehan, S. Seatter, C. Lord, R.D. Sturrock, M.M. Harnett, B cell receptor-stimulated mitochondrial phospholipase A2 activation and resultant disruption of mitochondrial membrane potential correlate with the induction of apoptosis in WEHI-231 B cells, J. Immunol. 166 (2001) 137-147.
12. L regulates the membrane potential and volume homeostasis of mitochondria, Cell 91 (1997) 627-637.
13. J.M. Jurgensmeier, Z. Xie, Q. Deveraux, L. Ellerby, D. Bredesen, J.C. Reed, Bax directly induces release of cytochrome c from isolated mitochondria, Proc. Natl. Acad. Sci. USA. 95 (1998) 4997-5002.
14. I. Marzo, C. Brenner, N. Zamzami, S.A. Susin, G. Beutner, D. Brdiczka, R. Remy, Z.H. Xie, J.C. Reed, G. Kroemer, The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins, J. Exp. Med. 187 (1998) 1261-1271.
15. J.C. Reed, Double identity for proteins of the Bcl-2 family, Nature 387 (1997) 773-776.
16. S.R. Datta, H. Dukek, X. Tao, S. Masters, H. Fu, Y. Gotoh, M.E. Greenberg, Akt phosphorylation of Bad couples survival signals to the cell intrinsic death machinery, Cell 91 (1997) 231-241.
17. S.R. Datta, A. Katsov, L. Hu, A. Petros, S.W. Fesik, M.B. Yaffe, M.E. Greenberg, 14-3-3 proteins and survival kinases cooperate to inactivate Bad by BH3 domain phosphorylation, Mol. Cell 6 (2000) 41-51.
18. L by the MAPK/Erk kinase, J. Biol. Chem. 274 (1999) 31108-31113.
19. S. Dramsi, M.P. Scheid, A. Aiti, P. Hojabrpour, X. Chen, K. Schubert, D.R. Goodlett, R. Aebersold, V. Duronio, Identification of a novel phosphorylation site, Ser-170, as a regulator of Bad pro-apoptotic activity, J. Biol. Chem. 277 (2002) 6399-6405.
20. S.R. Datta, A. Brunet, M.E. Greenberg, Cellular survival: A play in three Akts, Genes Dev. 13 (1999) 2905-2927.
21. V. Ayllon, A.C. Martinez, A. Garcia, X. Cayla, A. Rebollo, Protein phosphatase 1α is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosis, EMBO J. 19 (2000) 2237-2246.
22. J. Downward, How bad phosphorylation is good for survival, Nat. Cell Biol. 1 (1999) E33-E35.
23. M.R. Gold, M.P. Scheid, L. Santos, M. Dang-Lawson, R.A. Roth, L. Matsuuchi, V. Duronio, D.L. Krebs, The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase, J. Immunol. 163 (1999) 1894-1905.
24. Kip1 and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells, Oncogene 20 (2001) 7352-7367.
25. H. Harada, B. Becknell, M. Wilm, M. Mann, L.J. Huang, S.S. Taylor, J.D. Scott, S.J. Korsmeyer, Phosphorylation and inactivation of Bad by mitochondria-anchored protein kinase A, Mol. Cell 3 (1999) 413-422.
26. K. Virdee, P.A. Parone, A.M. Tolkovsky, Phosphorylation of the proapoptotic protein Bad on serine 155, a novel site, contributes to cell survival, Curr. Biol. 10 (2000) 1151-1154
27. H. Rottenberg, S. Wu, Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells, Biochim. Biophys. Acta 1404 (1998) 393-404.
28. J. Zha, H. Harada, E. Yang, J. Jockel, S.J. Korsmeyer, Serine phosphorylation of death agonist Bad in response to survival factor results in binding to 14-3-3 not Bcl-X(L), Cell 87 (1996) 619-628.
29. S.R. Datta, A.M. Ranger, M.Z. Lin, J.F. Sturgill, Y.-C. Ma, C.W. Cowan, P. Dikkes, S.J. Korsmeyer, M.E. Greenberg, Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis, Dev. Cell 3 (2002) 631-643.
30. M.S.K. Choi, L.H. Boise, A.R. Gottschalk, J. Quintans, C.B. Thompson, G.G. Klaus, The role of bcl-XL in CD40-mediated rescue from anti-mu-induced apoptosis in WEHI-231 B lymphoma cells, Eur. J. Immunol. 25 (1995) 1352-1357.
31. A. Bras, A. Ruiz-Vela, G. Gonzalez De Buitrago, A.C. Martinez, Caspase activation by BCR cross-linking in immature B cells: Differential effects on growth arrest and apoptosis, FASEB J. 13 (1999) 931-944.
32. A. Craxton, P.I. Chuang, G. Shu, J.M. Harlan, E.A. Clark, The CD40-inducible Bcl2-family member A1 protects B cells from antigen receptor-mediated apoptosis, Cell. Immunol. 200 (2000) 56-62.
33. A.W. Kuss, M. Knödel, F. Berberich-Siebelt, D. Lindemann, A. Schimpl, I. Berberich, A1 expression is stimulated by CD40 in B cells and rescues WEHI 231 cells from anti-IgM-induced cell death, Eur. J. Immunol. 29 (1999) 3077-3088.
34. S. Haldar, J. Nilamani, C.M. Croce, Inactivation of Bcl-2 by phosphorylation, Proc. Natl. Acad. Sci. USA 92 (1995) 4507-4511.
35. X.M. Zhou, Y. Liu, G. Payne, R. Lutz, R. Chittenden, Growth factors inactivate the cell death promoter Bad phosphorylation of its BH3 domain on serine 155, J. Biol. Chem. 275 (2000) 25046-25051.
36. G.B. Carey, D.W. Scott, Role of phosphatidylinositol 3-kinase in anti-IgM- and anti-IgD-induced apoptosis in B cell lymphomas, J. Immunol. 166 (2001) 1618-1626.
37. E. Malissein, M. Verdier, M.-H. Ratinaud, D. Troutaud, Bcl-2 protein phosphorylation/dephosphorylation and apoptosis induced by B cell antigen receptor ligation, In: S.G. Pandalai (Ed.), Recent Research Developments in Immunology, vol. 4, Research Signpost, Trivandrum, 2003 pp. 669-683.
38. H.J. Hindon, M.J. Welham, Cytokine-induced protein kinase B activation and Bad phosphorylation do not correlate with cell survival of hemopoietic cells, J. Immunol. 162 (1999) 7002-7009.
39. C.J. Jensen, M.-B. Buch, T.O. Krag, B.A. Hemmings, S. Gammeltoft, M. Frödin, 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1, J. Biol. Chem. 274 (1999) 27168-27176.
40. M.G. Gold, R. Aebersold, Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells, J. Immunol. 152 (1994) 42-50.
41. T.M. Yanke, E.A. Clark, Signaling through the B cell antigen receptor in developing B cells, Rev. Immunogenetics 2 (2000) 185-203.
42. V. Ayllon, A. Fleischer, X. Cayla, A. Garcia, A. Rebollo, Segregation of Bad from lipid rafts is implicated in the induction of apoptosis, J. Immunol. 168 (2002) 3387-3393.
43. T.T. Su, D.J. Rawlings, Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development, J. Immunol. 168 (2002) 2101-2110.
44. J.B. Petro, R.M. Gerstein, J. Love, R.S. Carter, N. Schinners, W.N. Khan Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling, J. Biol. Chem. 277 (2002) 48009-48019.
45. S. Klumpp, J. Krieglstein, Serine/threonine protein phosphatases in apoptosis, Curr. Opin. Pharmacol. 2 (2002) 458-462.
46. P. Cohen, C.F. Holmes, Y. Tsukitani, Okadaic acid: A new probe for the study of cellular regulation, Trends Biochem. Sci. 15 (1990) 98-102.