Genetic strategies for the treatment of sickle cell anaemia

British Journal of Haematology

Volumn 154, Issue 6, 2011, Pages 715-727

  Mansilla Soto, Jorge ^a   Rivière, Isabelle ^a   Sadelain, Michel ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Gene therapy; Globin gene; Homologous recombination; Lentiviral vector; Stem cells

Indexed keywords

DNA; GLOBIN; LENTIVIRUS VECTOR; NUCLEASE; OLIGONUCLEOTIDE; PSORALEN; RETROVIRUS VECTOR; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; ZINC FINGER NUCLEASE;

3' UNTRANSLATED REGION; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; BACTERIAL ARTIFICIAL CHROMOSOME; BIODEGRADABILITY; BLOOD VISCOSITY; BONE MARROW TRANSPLANTATION; CELL CYCLE S PHASE; CHIMERA; CORD BLOOD STEM CELL TRANSPLANTATION; ERYTHROPOIESIS; GENE EXPRESSION; GENE INDUCTION; GENE LOCUS; GENE MAPPING; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC TRANSCRIPTION; GRAFT REJECTION; HEMATOPOIESIS; HOMOLOGOUS RECOMBINATION; HOMOZYGOSITY; HUMAN; INTRON; MEAN CORPUSCULAR VOLUME; MURINE LEUKEMIA VIRUS; MUTAGENESIS; NONHUMAN; POLYADENYLATION; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; RETICULOCYTE COUNT; REVIEW; SEVERE COMBINED IMMUNODEFICIENCY; SICKLE CELL ANEMIA; TRANSGENE; WISKOTT ALDRICH SYNDROME;

GENE THERAPY; GLOBIN GENE; HOMOLOGOUS RECOMBINATION; LENTIVIRAL VECTOR; STEM CELLS;

ANEMIA, SICKLE CELL; ANIMALS; DISEASE MODELS, ANIMAL; GENE TARGETING; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; GLOBINS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; LENTIVIRUS; MICE;

EID: 80052273748     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2011.08773.x     Document Type: Review

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