Targeted cross-linking of the human β-globin gene in living cells mediated by a triple helix forming oligonucleotide

Biochemistry

Volumn 45, Issue 6, 2006, Pages 1970-1978

  Shahid, Kazi Abdus ^f   Majumdar, Alokes ^a   Alam, Rowshon ^a   Liu, Su Ting ^a   Kuan, Jean Y ^d   Sui, Xuifen ^a   Cuenoud, Bernard ^b   Glazer, Peter M ^d   Miller, Paul S ^c   Seidman, Michael M ^a,e  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

^f NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL REACTIONS; CROSSLINKING; GENES; PHOSPHATES; SYNTHESIS (CHEMICAL);

DUPLEX PHOSPHATES; LIVING CELLS; OLIGONUCLEOTIDE; TRIPLE HELIX FORMING OLIGONUCLEOTIDES (TFO);

GENETIC ENGINEERING;

2' O METHYLPSEUDOISOCYTIDINE; 8 OXOADENINE; ADENINE DERIVATIVE; BETA GLOBIN; CYTOSINE; CYTOSINE DERIVATIVE; METHYL GROUP; OLIGONUCLEOTIDE; PSORALEN; PURINE; PYRIMIDINE; TRIPLE HELIX FORMING OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; CROSS LINKING; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; GENE THERAPY; PRIORITY JOURNAL; PROTON TRANSPORT; SICKLE CELL ANEMIA; THERMOSTABILITY; TRIPLE HELIX;

ADENINE; ANEMIA, SICKLE CELL; BASE SEQUENCE; CROSS-LINKING REAGENTS; CYTIDINE; CYTOSINE; DNA; FICUSIN; GENE TARGETING; GLOBINS; HUMANS; HYDROGEN-ION CONCENTRATION; K562 CELLS; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PHOSPHATES; PURINES; PYRIMIDINES; TEMPERATURE; TUMOR CELLS, CULTURED;

EID: 32344447218     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0520986     Document Type: Article

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