Efficient and specific repair of sickle β-globin RNA by trans-splicing ribozymes

RNA

Volumn 9, Issue 10, 2003, Pages 1254-1263

  Byun, Jonghoe ^a   Lan, Ning ^a   Long, Meredith ^a   Sullenger, Bruce A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Efficiency; Ribozyme; RNA repair; Sickle globin; Specificity; Trans splicing

Indexed keywords

BETA GLOBIN; RIBOZYME; RNA;

ARTICLE; BASE PAIRING; EMBRYO; HUMAN; HUMAN CELL; KIDNEY CELL; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA REPAIR; RNA SPLICING;

ANEMIA, SICKLE CELL; BASE SEQUENCE; GLOBINS; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; POLYMERASE CHAIN REACTION; RNA; RNA, CATALYTIC; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANS-SPLICING; TRANSFECTION;

MAMMALIA;

EID: 0141743751     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1261/rna.5450203     Document Type: Article

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