Activation of human γ-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the γ-globin gene 5' flanking region

Gene

Volumn 242, Issue 1-2, 2000, Pages 219-228

  Xu, Xiaoxin S ^a   Glazer, Peter M ^b   Wang, Gan ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

globin gene; Gene activation; Gene therapy; Targeted mutagenesis; Triplex

Indexed keywords

GAMMA GLOBIN; HEMOGLOBIN F; OLIGONUCLEOTIDE; PLASMID DNA;

ARTICLE; BINDING SITE; DNA SEQUENCE; ERYTHROLEUKEMIA CELL; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE MUTATION; GENE THERAPY; HELA CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SICKLE CELL ANEMIA; SITE DIRECTED MUTAGENESIS; TRIPLE HELIX;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GLOBINS; HELA CELLS; HOST CELL FACTOR C1; HUMANS; K562 CELLS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OCTAMER TRANSCRIPTION FACTOR-1; OLIGONUCLEOTIDES; PROTEIN BINDING; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0033977775     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00522-3     Document Type: Article

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