A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin

Journal of Biological Chemistry

Volumn 279, Issue 26, 2004, Pages 27518-27524

  Levasseur, Dana N ^a   Ryan, Thomas M ^a   Reilly, Michael P ^b,c   McCune, Steven L ^a,d   Asakura, Toshio ^b   Townes, Tim M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d Northwest Georgia Oncology Centers   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; DISEASES; HEMOGLOBIN; MONOMERS; POLYPEPTIDES; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

CLINICAL TRIALS; TETRAMERS; TRANGENIC MICE;

BIOCHEMISTRY;

ALANINE; ALPHA GLOBIN; ANTISICKLING AGENT; ASPARTIC ACID; BETA GLOBIN; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HEMOGLOBIN F; HEMOGLOBIN S; MONOMER; OXYGEN; POLYMER; POLYPEPTIDE; PROTEIN SUBUNIT; RECOMBINANT HEMOGLOBIN; THREONINE;

ALPHA THALASSEMIA; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; COMPARATIVE STUDY; CONTROLLED STUDY; DIMERIZATION; ERYTHROCYTE; GENE EXPRESSION; HEMOGLOBIN SYNTHESIS; HUMAN; KNOCKOUT MOUSE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OXYGEN AFFINITY; POLYMERIZATION; PRIORITY JOURNAL; SICKLE CELL ANEMIA; TRANSGENIC MOUSE;

ADULT; ANEMIA, SICKLE CELL; ANIMALS; ANTISICKLING AGENTS; DISEASE MODELS, ANIMAL; ERYTHROCYTES, ABNORMAL; FETAL HEMOGLOBIN; GLOBINS; HEMATOLOGIC TESTS; HEMOGLOBINS; HUMANS; KIDNEY; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; SPLEEN;

ANIMALIA; MUS MUSCULUS;

EID: 3042597832     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402578200     Document Type: Article

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